Invitrogen

CD38 Monoclonal Antibody (HIT2), Qdot™ 800

FIGURE: 1 / 1

CD38 Antibody (Q22152) in Flow

Histogram overlay plot of gated human monocytes, the black line represents cells labeled with CD38 Mouse Anti-Human mAb (clone HIT2) Qdot® 800 Conjugate and the gray line represents unstained cells. Samples were acquired and analyzed using 405 nm excitation and a 780/60 band pass emission filter using the Attune® Acoustic Cytometer Blue/Violet option (Life Technologies, Carlsbad CA).

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Product Details

Q22152

Applications

Tested Dilution

Publications

Flow Cytometry (Flow)

Assay-dependent

Product Specifications

Host/Isotype

Mouse / IgG1

Class

Monoclonal

Type

Antibody

Clone

Immunogen

Human CD38

Conjugate

Qdot™ 800 Qdot™ 800 Qdot™ 800

Excitation/Emission Max

300/792 nm View spectra

Form

Liquid

Storage conditions

4° C

Target Information

CD38 (NAD+ glycohydrolase) is a type II transmembrane glycoprotein able to induce activation, proliferation and differentiation of mature lymphocytes and mediate apoptosis of myeloid and lymphoid progenitor cells. CD38 functions as a multi-catalytic ectoenzyme serving as ADP-ribosyl cyclase, cyclic ADP-ribose hydrolase and possibly NAD+ glycohydrolase or as a cell surface receptor. Antibodies to CD38 are useful in subtyping of lymphomas and leukemias, detection of plasma cells (i.e. identification of myelomas), and as a marker for activated B and T cells. CD38 participates in cell adhesion, signal transduction and calcium signaling. Further, CD38 is expressed at high levels in the pancreas, liver, kidney, malignant lymphoma and neuroblastoma. Diseases associated with CD38 dysfunction include chronic lymphocytic leukemia and Richter's Syndrome.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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