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Invitrogen
Human PIK3CB/PIK3R1 (p110 beta/p85 alpha), His Tag Recombinant Protein
Product Details
PV6455
Species
Expression System
Amino acid sequence
Tag
Molecular weight
Class
Type
Conjugate
Form
Concentration
Purification
Storage buffer
Contains
Storage conditions
Shipping conditions
Product Specific Information
For maximum recovery please spin prior to use. Unless noted below, aliquots of the 5 µg, 10 µg and 20 µg sizes of kinase are not recommended as materials can be used in original packaging until exhausted. For larger sizes, the number of freeze/thaws may be reduced by preparing aliquots, aliquots below 20 µL are not recommended. Please never store a kinase diluted. If properly stored at -80C, this product is guaranteed for 6 months from date of purchase.
PIK3CB/PIK3R1 (p110β/p85α) Recombinant Human Protein is:
• Available in 3 convenient sizes
• Validated in our Adapta™ and Kinase Binding assays
• A full-length protein that can help advance your research when used in validated assays
Related assay platforms:
LanthaScreen™ Kinase Binding Assay
Adapta™ Kinase Activity Assay
Protein Form: Full Length, Recombinant, Active
Target Information
PIK3CB/PIK3R1 (p110β/p85α) is a phosphoinositide-3-kinase (PI3K) comprised of a catalytic subunit, p110β, and a regulatory subunit, p85α, encoded by the PIK3CB and PIK3R1 genes respectively. As with other members of the PI3K family, p110β has important regulatory roles in cellular processes including cell survival, proliferation, and differentiation. It affects growth factor signaling and survival by phosphorylating inositol lipids. PTEN-deficient cancer cells have been observed to depend on p110β signaling.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Bioinformatics
Protein Aliases: Phosphatidylinositol 3-kinase 85 kDa regulatory subunit alpha; Phosphatidylinositol 3-kinase regulatory subunit alpha; phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 1 (p85 alpha); phosphatidylinositol 3-kinase-associated p-85 alpha; Phosphatidylinositol 4,5-bisphosphate 3-kinase 110 kDa catalytic subunit beta; Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform; phosphatidylinositol-4,5-bisphosphate 3-kinase 110 kDa catalytic subunit beta; phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta; phosphoinositide-3-kinase regulatory subunit; phosphoinositide-3-kinase regulatory subunit alpha; phosphoinositide-3-kinase, catalytic, beta polypeptide; phosphoinositide-3-kinase, regulatory subunit 1 (alpha); PI3-kinase p110 subunit beta; PI3-kinase regulatory subunit alpha; PI3-kinase subunit beta; PI3-kinase subunit p85-alpha; PI3K regulatory subunit alpha; PI3K-beta; PIK3CB; PIK3R1; PtdIns-3-kinase p110; ptdIns-3-kinase regulatory subunit alpha; ptdIns-3-kinase subunit beta; PtdIns-3-kinase subunit p110-beta; Serine/threonine protein kinase PIK3CB
Gene Aliases: AGM7; GRB1; IMD36; P110BETA; p85; p85-ALPHA; PI3K; PI3KBETA; PIK3C1; PIK3CB; PIK3R1
UniProt ID: (Human) P42338, (Human) P27986
Entrez Gene ID: (Human) 5291, (Human) 5295
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