For maximum recovery please spin prior to use. Unless noted below, aliquots of the 5 µg, 10 µg and 20 µg sizes of kinase are not recommended as materials can be used in original packaging until exhausted. For larger sizes, the number of freeze/thaws may be reduced by preparing aliquots, aliquots below 20 µL are not recommended. Please never store a kinase diluted. If properly stored at -80C, this product is guaranteed for 6 months from date of purchase.
Recombinant human KIT Y823D (544-end) was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.
• Validated in LanthaScreen™ Kinase Binding Assay
• Protocols available for simple use and optimized performance
• Multiple pack sizes available for convenient use
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Protein Form: Recombinant
KIT (c-KIT) Y823D encodes the ligand-binding chain (alpha) of the gamma interferon receptor which is a heterodimer of IFNGR1 and IFNGR2. KIT Y823D is a regulator of hematopoietic stem cells during homeostasis and under conditions of infectious stress. A genetic variation in KIT Y823D is associated with susceptibility to Helicobacter pylori infection. In addition, defects in KIT Y823D are a cause of mendelian susceptibility to mycobacterial disease, also known as familial disseminated atypical mycobacterial infection. KIT Y823D is also associated with the clinical outcome of HBV infection in Chinese adults.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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