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Invitrogen
NFkB p100 Polyclonal Antibody
This Antibody was verified by Knockout to ensure that the antibody binds to the antigen stated.
Product Details
PA5-27340
Species Reactivity
Published species
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Type
Immunogen
Conjugate
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Product Specific Information
Recommended positive controls: A431, HeLa, HepG2, NIH-3T3 , YY-8103.
Predicted reactivity: Mouse (91%), Rat (90%), Bovine (85%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
This gene encodes a subunit of the transcription factor complex nuclear factor-kappa-B (NFkB). The NFkB complex is expressed in numerous cell types and functions as a central activator of genes involved in inflammation and immune function. The protein encoded by this gene can function as both a transcriptional activator or repressor depending on its dimerization partner. The p100 full-length protein is co-translationally processed into a p52 active form. Chromosomal rearrangements and translocations of this locus have been observed in B cell lymphomas, some of which may result in the formation of fusion proteins. There is a pseudogene for this gene on chromosome 18. Alternative splicing results in multiple transcript variants.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: DNA-binding factor KBF2; H2TF1; Lymphocyte translocation chromosome 10 protein; Lyt10; NF kappaB2; NF-kB p100; NFKB, p52/p100 subunit; nuclear factor Kappa-B, subunit 2; Nuclear factor NF-kappa-B p100 subunit; nuclear factor NF-kappa-B p52 subunit; nuclear factor of Kappa light chain gene enhancer in B cells 2; Nuclear factor of kappa light polypeptide gene enhancer in B-cells 2; nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100); nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p100; Oncogene Lyt-10; transcription factor NFKB2
Gene Aliases: CVID10; H2TF1; lyt; LYT-10; LYT10; NF-kappaB2; NF-kB2; NFKB2; p100; p49; p49/p100; p50B; p52
UniProt ID: (Human) Q00653, (Mouse) Q9WTK5
Entrez Gene ID: (Human) 4791, (Mouse) 18034
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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