Product References
Antitumor effects of NK cells expanded by activation pre‑processing of autologous feeder cells before irradiation in colorectal cancer.
Oncology letters
Koh EK,Lee HR,Son WC,Park GY,Bae J,Park YS
MA5-13070 was used in Immunocytochemistry to conclude that combined radiotherapy and antibody-based immunotherapy with expanded NK cells may be an effective strategy to enhance the efficiency of treatment against colorectal cancer.
Thu Jun 01 00:00:00 EDT 2023
CMTM5 inhibits the development of prostate cancer via the EGFR/PI3K/AKT signaling pathway.
Molecular medicine reports
Li L,Hu Y,Chen D,Zhu J,Bao W,Xu X,Chen H,Chen W,Feng R
Published figure using EGFR monoclonal antibody (Product # MA5-13070) in Immunohistochemistry
Sat Jan 01 00:00:00 EST 2022
CMTM5 inhibits the development of prostate cancer via the EGFR/PI3K/AKT signaling pathway.
Molecular medicine reports
Li L,Hu Y,Chen D,Zhu J,Bao W,Xu X,Chen H,Chen W,Feng R
Published figure using EGFR monoclonal antibody (Product # MA5-13070) in Immunohistochemistry
Sat Jan 01 00:00:00 EST 2022
Ramucirumab combination with sorafenib enhances the inhibitory effect of sorafenib on HepG2 cancer cells.
Scientific reports
Taha AM,Aboulwafa MM,Zedan H,Helmy OM
Published figure using EGFR monoclonal antibody (Product # MA5-13070) in Western Blot
Tue Oct 25 00:00:00 EDT 2022
EGFR-Targeted Photodynamic Therapy.
Pharmaceutics
Ulfo L,Costantini PE,Di Giosia M,Danielli A,Calvaresi M
MA5-13070 was used in Western Blot to review the recent nanobiotechnological advancements that combine the promise of photodynamic therapy with EGFR-targeted molecular cancer therapy.
Thu Jan 20 00:00:00 EST 2022
Epigenetic silencing and tumor suppressor gene of HAND2 by targeting ERK signaling in colorectal cancer.
Cell communication and signaling : CCS
Yuan Z,Yu X,Chen W,Chen D,Cai J,Jiang Y,Liu X,Wu Z,Wang L,Grady WM,Wang H
MA5-13070 was used in RT-qPCR to identify epigenetic silenced genes and clarify its roles and underlying mechanism in CRC.
Sat Jul 23 00:00:00 EDT 2022
Analysis of Increased EGFR and IGF-1R Signaling and Its Correlation with Socio-Epidemiological Features and Biological Profile in Breast Cancer Patients: A Study in Northern Brazil.
Breast cancer (Dove Medical Press)
Silva Rocha F,da Silva Maués JH,Brito Lins Pereira CM,Moreira-Nunes CA,Rodriguez Burbano RM
MA5-13070 was used in Immunohistochemistry (Paraffin) to to evaluate the prognostic and predictive values of the EGFR and IGF-1R in tumor samples from patients with BC and their correlation with socio-epidemiological features.
Sat Apr 23 00:00:00 EDT 2022
The prognostic and predictive significance of cytokeratin 5/6 and epidermal growth factor receptor in metastatic triple-negative breast cancer treated with maintenance capecitabine.
Translational cancer research
Zhu Y,Li K,Zhang J,Wang L,Sheng L,Yan L
MA5-13070 was used in Immunohistochemistry to investigate the correlation between CK5/6 and EGFR expression and triple-negative breast cancer prognosis, and the efficacy of capecitabine maintenance.
Mon Mar 01 00:00:00 EST 2021
The prognostic and predictive significance of cytokeratin 5/6 and epidermal growth factor receptor in metastatic triple-negative breast cancer treated with maintenance capecitabine.
Translational cancer research
Zhu Y,Li K,Zhang J,Wang L,Sheng L,Yan L
MA5-13070 was used in Immunohistochemistry to investigate the correlation between CK5/6 and EGFR expression and triple-negative breast cancer prognosis, and the efficacy of capecitabine maintenance.
Mon Mar 01 00:00:00 EST 2021
Growth and site-specific organization of micron-scale biomolecular devices on living mammalian cells.
Nature communications
Jia S,Phua SC,Nihongaki Y,Li Y,Pacella M,Li Y,Mohammed AM,Sun S,Inoue T,Schulman R
MA5-13070 was used in Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot to integrate synthetic devices, micron-scale DNA nanotubes, with mammalian cells by anchoring them by their ends to specific cell surface receptors.
Thu Sep 30 00:00:00 EDT 2021
Growth and site-specific organization of micron-scale biomolecular devices on living mammalian cells.
Nature communications
Jia S,Phua SC,Nihongaki Y,Li Y,Pacella M,Li Y,Mohammed AM,Sun S,Inoue T,Schulman R
MA5-13070 was used in Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot to integrate synthetic devices, micron-scale DNA nanotubes, with mammalian cells by anchoring them by their ends to specific cell surface receptors.
Thu Sep 30 00:00:00 EDT 2021
Mammalian Expression and In Situ Biotinylation of Extracellular Protein Targets for Directed Evolution.
ACS omega
Grindel BJ,Engel BJ,Hall CG,Kelderhouse LE,Lucci A,Zacharias NM,Takahashi TT,Millward SW
MA5-13070 was used in Western Blotting to allow rapid purification of high-quality targets for directed evolution and selective elution of functional sequences at the conclusion of each selection round.
Tue Oct 06 00:00:00 EDT 2020
Mammalian Expression and In Situ Biotinylation of Extracellular Protein Targets for Directed Evolution.
ACS omega
Grindel BJ,Engel BJ,Hall CG,Kelderhouse LE,Lucci A,Zacharias NM,Takahashi TT,Millward SW
MA5-13070 was used in Western Blotting to allow rapid purification of high-quality targets for directed evolution and selective elution of functional sequences at the conclusion of each selection round.
Tue Oct 06 00:00:00 EDT 2020
Proteomics identifies EGF-like domain multiple 7 as a potential therapeutic target for epidermal growth factor receptor-positive glioma.
Cancer communications (London, England)
Wang FY,Wang-Gou SY,Cao H,Jiang N,Yang Q,Huang Q,Huang CH,Li XJ
MA5-13070 was used in Immunocytochemistry-Immunofluorescence to investigate the role of the EGF-EGFR-angiogenesis axis in tumorgenesis of glioma and access the therapeutic efficacy of selumetinib on glioma using proteomic techniques.
Thu Oct 01 00:00:00 EDT 2020
Multiplexed Targeting of Barrett's Neoplasia with a Heterobivalent Ligand: Imaging Study on Mouse Xenograft in Vivo and Human Specimens ex Vivo.
Journal of medicinal chemistry
Chen J,Zhou J,Gao Z,Li X,Wang F,Duan X,Li G,Joshi BP,Kuick R,Appelman HD,Wang TD
Published figure using EGFR monoclonal antibody (Product # MA5-13070) in Immunohistochemistry
Thu Jun 28 00:00:00 EDT 2018
Distinction Between Active and Passive Targeting of Nanoparticles Dictate Their Overall Therapeutic Efficacy.
Langmuir : the ACS journal of surfaces and colloids
Clemons TD,Singh R,Sorolla A,Chaudhari N,Hubbard A,Iyer KS
MA5-13070 was used in Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot, In Vitro Assay to demonstrate that the intracellular destination of nanoparticles beyond its ability to internalize is an important parameter that has to be accounted for in the design of targeted drug delivery systems.
Tue Dec 18 00:00:00 EST 2018
Distinguishing between irritated seborrheic keratosis and squamous cell carcinoma in situ using BCL-2 and IMP3 immunohistochemistry.
Journal of cutaneous pathology
Richey JD,Deng AC,Dresser K,O'Donnell P,Cornejo KM
MA5-13070 was used in Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot to indicate that the combination of IMP3 and BCL-2 may be of diagnostic utility in distinguishing between ISK and SCCIS in daily clinical practice.
Wed Aug 01 00:00:00 EDT 2018
Sortilin limits EGFR signaling by promoting its internalization in lung cancer.
Nature communications
Al-Akhrass H,Naves T,Vincent F,Magnaudeix A,Durand K,Bertin F,Melloni B,Jauberteau MO,Lalloué F
Published figure using EGFR monoclonal antibody (Product # MA5-13070) in Western Blot
Mon Oct 30 00:00:00 EDT 2017
MUC1 stimulates EGFR expression and function in endometrial cancer.
Oncotarget
Engel BJ,Bowser JL,Broaddus RR,Carson DD
MA513070 was used in immunohistochemistry and western blot to determine that MUC1 stimulates epidermal growth factor receptor expression and function in endometrial cancer
Tue May 31 00:00:00 EDT 2016
Multilayered, Hyaluronic Acid-Based Hydrogel Formulations Suitable for Automated 3D High Throughput Drug Screening of Cancer-Stromal Cell Cocultures.
Advanced healthcare materials
Engel BJ,Constantinou PE,Sablatura LK,Doty NJ,Carson DD,Farach-Carson MC,Harrington DA,Zarembinski TI
MA5-13070 was used in immunocytochemistry to use a high-throughput 3D hyaluronic acid hydrogel coculture of cancer cells with stromal cells to evaluate chemotherapeutics
Wed Aug 05 00:00:00 EDT 2015
Efficacy and mechanism of action of Proellex, an antiprogestin in aromatase overexpressing and Letrozole resistant T47D breast cancer cells.
The Journal of steroid biochemistry and molecular biology
Gupta A,Mehta R,Alimirah F,Peng X,Murillo G,Wiehle R,Mehta RG
MA5-13070 was used in immunocytochemistry to study the efficacy and anti-prolifferative mechanism of Proellex in breast cancer cells overexpressing aromatase and resistant to Letrozole
Tue Jan 01 00:00:00 EST 2013
Trastuzumab induces antibody-dependent cell-mediated cytotoxicity (ADCC) in HER-2-non-amplified breast cancer cell lines.
Annals of oncology : official journal of the European Society for Medical Oncology
Collins DM,O'Donovan N,McGowan PM,O'Sullivan F,Duffy MJ,Crown J
MA5-13070 was used in western blot to study the induction of antibody-dependent cell-mediated cytotoxicity in HER-2-non-amplified breast cancer cells by trastuzumab
Sun Jul 01 00:00:00 EDT 2012
Triepitopic antibody fusions inhibit cetuximab-resistant BRAF and KRAS mutant tumors via EGFR signal repression.
Journal of molecular biology
Spangler JB,Manzari MT,Rosalia EK,Chen TF,Wittrup KD
MA5-13070 was used in blocking or activating experiment to study the therapeutic effects against cetuximab-resistant BRAF and KRAS mutant tumors of an antibody fusion protein that recognizes three EGFR epitopes
Fri Sep 28 00:00:00 EDT 2012
Coexpression of SGLT1 and EGFR is associated with tumor differentiation in oral squamous cell carcinoma.
Odontology
Hanabata Y,Nakajima Y,Morita K,Kayamori K,Omura K
MA5-13070 was used in western blot to investigate the relationship between SGLT1 and EGFR gene expression and tumor differetiation in oral squamous cell carcinoma
Sun Jul 01 00:00:00 EDT 2012
Quantitative assays for the measurement of HER1-HER2 heterodimerization and phosphorylation in cell lines and breast tumors: applications for diagnostics and targeted drug mechanism of action.
Breast cancer research : BCR
DeFazio-Eli L,Strommen K,Dao-Pick T,Parry G,Goodman L,Winslow J
MA5-13070 was used in immunoprecipitation to investigate the state of HER1-HER2 interaction and modification in cell lines and tumors
Fri Apr 15 00:00:00 EDT 2011
Enrichment of circulating tumor cells from a large blood volume using leukapheresis and elutriation: proof of concept.
Cytometry. Part B, Clinical cytometry
Eifler RL,Lind J,Falkenhagen D,Weber V,Fischer MB,Zeillinger R
MA5-13070 was used in immunocytochemistry to develop a process involving leukapheresis, elutriation and FACS to isolate circulating tumor cells from large volumes
Tue Mar 01 00:00:00 EST 2011
Determination of the minimal melatonin exposure required to induce osteoblast differentiation from human mesenchymal stem cells and these effects on downstream signaling pathways.
Journal of pineal research
Sethi S,Radio NM,Kotlarczyk MP,Chen CT,Wei YH,Jockers R,Witt-Enderby PA
MA5-13070 was used in western blot to determine the minimal period of melatonin treatment required to induce the differentiation of human mesenchymal stem cells into osteoblasts
Fri Oct 01 00:00:00 EDT 2010
Design of surfaces for liquid crystal-based bioanalytical assays.
ACS applied materials & interfaces
Lowe AM,Ozer BH,Bai Y,Bertics PJ,Abbott NL
MA5-13070 was used in blocking or activating experiment to investigate the liquid crystal-based bioanalytical assays
Mon Mar 01 00:00:00 EST 2010
Activity and cellular localization of an oncogenic glioblastoma multiforme-associated EGF receptor mutant possessing a duplicated kinase domain.
Oncogene
Ozer BH,Wiepz GJ,Bertics PJ
MA5-13070 was used in immunohistochemistry to describe an EGF receptor mutant with tandem kinase domain duplication in glioblastoma multiforme biopsies and cell lines
Thu Feb 11 00:00:00 EST 2010
Evaluation of PTEN and Mcl-1 expressions in NSCLC expressing wild-type or mutated EGFR.
Medical oncology (Northwood, London, England)
Cetin Z,Ozbilim G,Erdogan A,Luleci G,Karauzum SB
MA5-13070 was used in western blot to study the expression of PTEN, Mcl-1 and EGFR in non-small cell lung cancer
Wed Sep 01 00:00:00 EDT 2010
Overexpression of cortactin increases invasion potential in oral squamous cell carcinoma.
Pathology oncology research : POR
Yamada S,Yanamoto S,Kawasaki G,Mizuno A,Nemoto TK
MA5-13070 was used in western blot to study the role of cortactin overexpression in increasing invasion potential in oral squamous cell carcinoma
Wed Dec 01 00:00:00 EST 2010
Erlotinib and bevacizumab have synergistic activity against melanoma.
Clinical cancer research : an official journal of the American Association for Cancer Research
Schicher N,Paulitschke V,Swoboda A,Kunstfeld R,Loewe R,Pilarski P,Pehamberger H,Hoeller C
MA5-13070 was used in western blot to study the effect of combined treatment with erlotinib and bevacizumab against melanoma
Fri May 15 00:00:00 EDT 2009
miR-200 expression regulates epithelial-to-mesenchymal transition in bladder cancer cells and reverses resistance to epidermal growth factor receptor therapy.
Clinical cancer research : an official journal of the American Association for Cancer Research
Adam L,Zhong M,Choi W,Qi W,Nicoloso M,Arora A,Calin G,Wang H,Siefker-Radtke A,McConkey D,Bar-Eli M,Dinney C
MA5-13070 was used in western blot to study the effect of miR-200 expression on the epithelial-to-mesenchymal transition and resistance to EGFR therapy in bladder cancer cells
Sat Aug 15 00:00:00 EDT 2009
Sennoside B inhibits PDGF receptor signaling and cell proliferation induced by PDGF-BB in human osteosarcoma cells.
Life sciences
Chen YC,Chang CN,Hsu HC,Chiou SJ,Lee LT,Hseu TH
MA5-13070 was used in western blot to study the role of PDGF signaling in the inhibition of osteosarcoma cell proliferation by sennoside B
Fri Jun 19 00:00:00 EDT 2009
Proteomic and immunologic analyses of brain tumor exosomes.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Graner MW,Alzate O,Dechkovskaia AM,Keene JD,Sampson JH,Mitchell DA,Bigner DD
MA5-13070 was used in western blot to investigate brain tumor exosomes by biochemical, proteomic, and immunological approaches
Fri May 01 00:00:00 EDT 2009
Sensitivity to epidermal growth factor receptor inhibitor requires E-cadherin expression in urothelial carcinoma cells.
Clinical cancer research : an official journal of the American Association for Cancer Research
Black PC,Brown GA,Inamoto T,Shrader M,Arora A,Siefker-Radtke AO,Adam L,Theodorescu D,Wu X,Munsell MF,Bar-Eli M,McConkey DJ,Dinney CP
MA5-13070 was used in western blot to study molecular markers of the response to cetuximab therapy in a panel of urothelial carcinoma cell lines
Sat Mar 01 00:00:00 EST 2008
Engineering of PDMS surfaces for use in microsystems for capture and isolation of complex and biomedically important proteins: epidermal growth factor receptor as a model system.
Lab on a chip
Lowe AM,Ozer BH,Wiepz GJ,Bertics PJ,Abbott NL
MA5-13070 was used in immunoprecipitation to develop a novel system for capture and isolation of biomedically important proteins
Fri Aug 01 00:00:00 EDT 2008
Overexpression of JKTBP1 induces androgen-independent LNCaP cell proliferation through activation of epidermal growth factor-receptor (EGF-R).
Cell biochemistry and function
Wu YY,Li H,Lv XY,Wei Q,Li X,Liu XY,Zhou Q,Wei YQ
MA5-13070 was used in western blot to investigate the effect of heterogenous nuclear ribonucleoprotein D-like protein on androgen-independent LNCaP cell proliferation
Sun Jun 01 00:00:00 EDT 2008
Structure-guided development of affinity probes for tyrosine kinases using chemical genetics.
Nature chemical biology
Blair JA,Rauh D,Kung C,Yun CH,Fan QW,Rode H,Zhang C,Eck MJ,Weiss WA,Shokat KM
MA5-13070 was used in western blot to develop tyrosine kinase affinity probes using chemical genetics
Sun Apr 01 00:00:00 EDT 2007
EGF-independent activation of cell-surface EGF receptors harboring mutations found in gefitinib-sensitive lung cancer.
Oncogene
Choi SH,Mendrola JM,Lemmon MA
MA5-13070 was used in immunocytochemistry to study EGF-independent activation of mutant cell-surface EGF receptors in gefitinib-sensitive lung cancer
Thu Mar 08 00:00:00 EST 2007
Radiotherapy response in oral squamous carcinoma cell lines: evaluation of apoptotic proteins as prognostic factors.
Head & neck
Roberg K,Jonsson AC,Grénman R,Norberg-Spaak L
MA5-13070 was used in western blot to investigate the effect of apoptotic proteins on the radiosensitivity of oral squamous carcinoma cell line
Sun Apr 01 00:00:00 EDT 2007
Type II combi-molecules: design and binary targeting properties of the novel triazolinium-containing molecules JDD36 and JDE05.
Anti-cancer drugs
Qiu Q,Domarkas J,Banerjee R,Katsoulas A,McNamee JP,Jean-Claude BJ
MA5-13070 was used in western blot to study the EGFR-targeting potential of novel triazolinium-containing "combi-molecules
Thu Feb 01 00:00:00 EST 2007
A dual PI3 kinase/mTOR inhibitor reveals emergent efficacy in glioma.
Cancer cell
Fan QW,Knight ZA,Goldenberg DD,Yu W,Mostov KE,Stokoe D,Shokat KM,Weiss WA
MA5-13070 was used in western blot to study the efficacy of a dual PI3 kinase/mTOR inhibitor in glioma
Mon May 01 00:00:00 EDT 2006
Novel toll-like receptor 9 agonist induces epidermal growth factor receptor (EGFR) inhibition and synergistic antitumor activity with EGFR inhibitors.
Clinical cancer research : an official journal of the American Association for Cancer Research
Damiano V,Caputo R,Bianco R,D'Armiento FP,Leonardi A,De Placido S,Bianco AR,Agrawal S,Ciardiello F,Tortora G
MA5-13070 was used in western blot to investigate the effect of a novel toll-like receptor 9 agonist on epidermal growth factor receptor inhibition and on tumor growth
Sun Jan 15 00:00:00 EST 2006
Multiple acquired renal carcinoma tumor capabilities abolished upon silencing of ADAM17.
Cancer research
Franovic A,Robert I,Smith K,Kurban G,Pause A,Gunaratnam L,Lee S
MA5-13070 was used in western blot to study the effect of ADAM17 silencing on multiple acquired renal carcinoma tumor capabilities
Tue Aug 15 00:00:00 EDT 2006
Estrogen receptors in membrane lipid rafts and signal transduction in breast cancer.
Molecular and cellular endocrinology
Márquez DC,Chen HW,Curran EM,Welshons WV,Pietras RJ
MA5-13070 was used in western blot to study the role of estrogen receptors in membrane lipid rafts in breast cancer signal transduction
Sun Feb 26 00:00:00 EST 2006
Uncoupling between epidermal growth factor receptor and downstream signals defines resistance to the antiproliferative effect of Gefitinib in bladder cancer cells.
Cancer research
Kassouf W,Dinney CP,Brown G,McConkey DJ,Diehl AJ,Bar-Eli M,Adam L
MA5-13070 was used in western blot to study the mechanism of resistance to the EGFR tyrosine kinase inhibitor Gefitinib in bladder cancer cells
Tue Nov 15 00:00:00 EST 2005
Herpes simplex virus 1 amplicon vector-mediated siRNA targeting epidermal growth factor receptor inhibits growth of human glioma cells in vivo.
Molecular therapy : the journal of the American Society of Gene Therapy
Saydam O,Glauser DL,Heid I,Turkeri G,Hilbe M,Jacobs AH,Ackermann M,Fraefel C
MA5-13070 was used in western blot to study whether gene silencing by vector-mediated RNAi inhibition of EGFR expression can reduce the growth of cultured human glioma cells
Tue Nov 01 00:00:00 EST 2005
In vivo antitumor activity of NVP-AEW541-A novel, potent, and selective inhibitor of the IGF-IR kinase.
Cancer cell
García-Echeverría C,Pearson MA,Marti A,Meyer T,Mestan J,Zimmermann J,Gao J,Brueggen J,Capraro HG,Cozens R,Evans DB,Fabbro D,Furet P,Porta DG,Liebetanz J,Martiny-Baron G,Ruetz S,Hofmann F
MA5-13070 was used in ELISA to study the in vivo antitumor activity of a potent and selective IGF-1 receptor kinase inhibitor
Mon Mar 01 00:00:00 EST 2004
Inhibition of the type III epidermal growth factor receptor variant mutant receptor by dominant-negative EGFR-CD533 enhances malignant glioma cell radiosensitivity.
Clinical cancer research : an official journal of the American Association for Cancer Research
Lammering G,Hewit TH,Holmes M,Valerie K,Hawkins W,Lin PS,Mikkelsen RB,Schmidt-Ullrich RK
MA5-13070 was used in immunoprecipitation to study the role and therapuetic potential of the EGFR type III in modulating cellular responses to ionizing radiation
Fri Oct 01 00:00:00 EDT 2004
AEE788: a dual family epidermal growth factor receptor/ErbB2 and vascular endothelial growth factor receptor tyrosine kinase inhibitor with antitumor and antiangiogenic activity.
Cancer research
Traxler P,Allegrini PR,Brandt R,Brueggen J,Cozens R,Fabbro D,Grosios K,Lane HA,McSheehy P,Mestan J,Meyer T,Tang C,Wartmann M,Wood J,Caravatti G
MA5-13070 was used in ELISA to suggest that AEE788 is an anticancer agent that deregulates tumor cell proliferation and angiogenic parameters
Thu Jul 15 00:00:00 EDT 2004
Expression of a naturally occurring constitutively active variant of the epidermal growth factor receptor in mouse fibroblasts increases motility.
International journal of cancer
Pedersen MW,Tkach V,Pedersen N,Berezin V,Poulsen HS
MA5-13070 was used in western blot to study the role of a constitutively active variant of the EGFR in increasing mouse fibroblast motility
Fri Feb 20 00:00:00 EST 2004
HER-2/neu overexpression increases the viable hypoxic cell population within solid tumors without causing changes in tumor vascularization.
Molecular cancer research : MCR
Dragowska WH,Warburton C,Yapp DT,Minchinton AI,Hu Y,Waterhouse DN,Gelmon K,Skov K,Woo J,Masin D,Huxham LA,Kyle AH,Bally MB
MA5-13070 was used in flow cytometry to study the role of HER-2/neu overexpression in increasing the viable hypoxic cell population within solid tumors
Mon Nov 01 00:00:00 EST 2004
The combi-targeting concept: dissection of the binary mechanism of action of the combi-triazene SMA41 in vitro and antitumor activity in vivo.
The Journal of pharmacology and experimental therapeutics
Matheson SL,McNamee JP,Wang T,Alaoui-Jamali MA,Tari AM,Jean-Claude BJ
MA5-13070 was used in western blot to study the anti-tumor mechanism of a unimolecular combination of an EGFR tyrosine kinase inhibitor and a DNA damaging triazine
Wed Dec 01 00:00:00 EST 2004
Domain-level antibody epitope mapping through yeast surface display of epidermal growth factor receptor fragments.
Journal of immunological methods
Cochran JR,Kim YS,Olsen MJ,Bhandari R,Wittrup KD
MA5-13070 was used in flow cytometry to study the use of yeast surface display for identifying stable folded protein domains and characterizing antibody binding epitopes
Thu Apr 01 00:00:00 EST 2004
Broadly distributed chemical reactivity of natural antibodies expressed in coordination with specific antigen binding activity.
The Journal of biological chemistry
Planque S,Taguchi H,Burr G,Bhatia G,Karle S,Zhou YX,Nishiyama Y,Paul S
MA5-13070 was used in EMSA to investigate the nucleophilic reactivity of natural antibodies
Fri May 30 00:00:00 EDT 2003
Neuregulin expression, function, and signaling in human ovarian cancer cells.
Clinical cancer research : an official journal of the American Association for Cancer Research
Gilmour LM,Macleod KG,McCaig A,Sewell JM,Gullick WJ,Smyth JF,Langdon SP
MA5-13070 was used in western blot to investigate the characteristics of neuregulin in human ovarian cancer cells
Sun Dec 01 00:00:00 EST 2002
Epidermal growth factor receptor mutation type III transfected into a small cell lung cancer cell line is predominantly localized at the cell surface and enhances the malignant phenotype.
International journal of cancer
Damstrup L,Wandahl Pedersen M,Bastholm L,Elling F,Skovgaard Poulsen H
MA5-13070 was used in immunohistochemistry and western blot to study the role of EGFR mutation type III in enhancing the malignant phenotype in a small cell lung cancer cell line
Tue Jan 01 00:00:00 EST 2002
Inhibition of epidermal growth factor receptor-mediated signaling by "Combi-triazene" BJ2000, a new probe for Combi-Targeting postulates.
The Journal of pharmacology and experimental therapeutics
Brahimi F,Matheson SL,Dudouit F,McNamee JP,Tari AM,Jean-Claude BJ
MA5-13070 was used in western blot to study the inhibition of EGFR-mediated signaling by a "Combi-triazene" molecule with binary EGFR targeting/DNA-damaging properties
Tue Oct 01 00:00:00 EDT 2002
Adenovirus-mediated overexpression of dominant negative epidermal growth factor receptor-CD533 as a gene therapeutic approach radiosensitizes human carcinoma and malignant glioma cells.
International journal of radiation oncology, biology, physics
Lammering G,Lin PS,Contessa JN,Hampton JL,Valerie K,Schmidt-Ullrich RK
MA5-13070 was used in western blot to study the use of adenovirus-mediated overexpression of dominant negative EGFR to radiosensitize human carcinoma and malignant glioma cells
Thu Nov 01 00:00:00 EST 2001
Cell migration and MMP-9 secretion are increased by epidermal growth factor in HaCaT-ras transfected cells.
Experimental dermatology
Charvat S,Chignol MC,Souchier C,Le Griel C,Schmitt D,Serres M
MA5-13070 was used in flow cytometry to study the effect of epidermal growth factor and HaCaT-ras on MMP-9 expression and cell migration
Sat Aug 01 00:00:00 EDT 1998
Physical interaction between epidermal growth factor receptor and DNA-dependent protein kinase in mammalian cells.
The Journal of biological chemistry
Bandyopadhyay D,Mandal M,Adam L,Mendelsohn J,Kumar R
MA5-13070 was used in western blot to study the biological functions of the epidermal growth factor receptor and DNA-dependent protein kinase interaction
Fri Jan 16 00:00:00 EST 1998