Product References
The Alpha Isoform of Heat Shock Protein 90 and the Co-chaperones p23 and Cdc37 Promote Opioid Anti-nociception in the Brain.
Frontiers in molecular neuroscience
Lei W,Duron DI,Stine C,Mishra S,Blagg BSJ,Streicher JM
MA3-414 was used in Immunohistochemistry to provide insight into the molecular mechanisms by which Hsp90 promotes opioid anti-nociception.
Fri Oct 20 00:00:00 EDT 2023
In silico identification and biochemical characterization of the human dicarboxylate clamp TPR protein interaction network.
FEBS open bio
Bernadotte A,Kumar R,Winblad B,Pavlov PF
MA3-414 was used in Immunocytochemistry-immunoflourescence to identify and characterise the human dicarboxylate clamp tetratricopeptide repeat protein interaction network.
Thu Nov 01 00:00:00 EDT 2018
In silico identification and biochemical characterization of the human dicarboxylate clamp TPR protein interaction network.
FEBS open bio
Bernadotte A,Kumar R,Winblad B,Pavlov PF
MA3-414 was used in Immunocytochemistry-immunoflourescence to identify and characterise the human dicarboxylate clamp tetratricopeptide repeat protein interaction network.
Thu Nov 01 00:00:00 EDT 2018
Hsp70 cochaperones HspBP1 and BAG-1M differentially regulate steroid hormone receptor function.
PloS one
Knapp RT,Wong MJ,Kollmannsberger LK,Gassen NC,Kretzschmar A,Zschocke J,Hafner K,Young JC,Rein T
MA3-414 was used in western blot to study the functional regulation of steroid hormone receptors by the Hsp70 co-chaperones HspBP1 and GAG-1M
Wed Sep 17 00:00:00 EDT 2014
Hsp90 cochaperones p23 and FKBP4 physically interact with hAgo2 and activate RNA interference-mediated silencing in mammalian cells.
Molecular biology of the cell
Pare JM,LaPointe P,Hobman TC
MA3-414 was used in western blot to study the interaction of p23 and FKBP4 with hAgo2 and their roles in the mechanism of mammalian cell RNAi silencing
Thu Aug 01 00:00:00 EDT 2013
pRb controls estrogen receptor alpha protein stability and activity.
Oncotarget
Caligiuri I,Toffoli G,Giordano A,Rizzolio F
MA3-414 was used in western blot to investigate cross talk between the estrogen receptor and the retinoblastoma pathway
Sat Jun 01 00:00:00 EDT 2013
Hsp70 and Hsp90 multichaperone complexes sequentially regulate thiazide-sensitive cotransporter endoplasmic reticulum-associated degradation and biogenesis.
The Journal of biological chemistry
Donnelly BF,Needham PG,Snyder AC,Roy A,Khadem S,Brodsky JL,Subramanya AR
MA3-414 was used in western blot to study the role of Hsp70 and Hsp90 in the endoplasmic reticulum quality control of the thiazide-sensitive NaCl co-transporter
Fri May 03 00:00:00 EDT 2013
p23 co-chaperone protects the aryl hydrocarbon receptor from degradation in mouse and human cell lines.
Biochemical pharmacology
Nguyen PM,Wang D,Wang Y,Li Y,Uchizono JA,Chan WK
MA3-414 was used in western blot to study the role of p23 in protecting the aryl hydrocarbon receptor against degradation
Sat Sep 15 00:00:00 EDT 2012
Type 1 inositol-1,4,5-trisphosphate receptor is a late substrate of caspases during apoptosis.
Journal of cellular biochemistry
Elkoreh G,Blais V,Béliveau E,Guillemette G,Denault JB
MA3-414 was used in western blot to study role of the type 1 inositol-1,4,5-trisphosphate receptor as an apoptotic substrate of caspases
Wed Aug 01 00:00:00 EDT 2012
Molecular determinants involved in activation of caspase 7.
Bioscience reports
Boucher D,Blais V,Drag M,Denault JB
MA3-414 was used in western blot to investigate the caspase activation pathway during apoptosis
Mon Aug 01 00:00:00 EDT 2011
Caspase-1 promiscuity is counterbalanced by rapid inactivation of processed enzyme.
The Journal of biological chemistry
Walsh JG,Logue SE,Lüthi AU,Martin SJ
MA3-414 was used in western blot to investigate the substrate specificity of caspase-1
Fri Sep 16 00:00:00 EDT 2011
High levels of Hsp90 cochaperone p23 promote tumor progression and poor prognosis in breast cancer by increasing lymph node metastases and drug resistance.
Cancer research
Simpson NE,Lambert WM,Watkins R,Giashuddin S,Huang SJ,Oxelmark E,Arju R,Hochman T,Goldberg JD,Schneider RJ,Reiz LF,Soares FA,Logan SK,Garabedian MJ
MA3-414 was used in immunohistochemistry to investigate the mechanism of Hsp90 cochaperone p23 in tumor progression and poor prognosis in breast cancer
Mon Nov 01 00:00:00 EDT 2010
High levels of Hsp90 cochaperone p23 promote tumor progression and poor prognosis in breast cancer by increasing lymph node metastases and drug resistance.
Cancer research
Simpson NE,Lambert WM,Watkins R,Giashuddin S,Huang SJ,Oxelmark E,Arju R,Hochman T,Goldberg JD,Schneider RJ,Reiz LF,Soares FA,Logan SK,Garabedian MJ
MA3-414 was used in immunohistochemistry to investigate the mechanism of Hsp90 cochaperone p23 in tumor progression and poor prognosis in breast cancer
Mon Nov 01 00:00:00 EDT 2010
Glucose deprivation induces an atypical form of apoptosis mediated by caspase-8 in Bax-, Bak-deficient cells.
Cell death and differentiation
Caro-Maldonado A,Tait SW,Ramírez-Peinado S,Ricci JE,Fabregat I,Green DR,Muñoz-Pinedo C
MA3-414 was used in western blot to investigate the mechanism of apoptosis induced by glucose deprivation in Bax- and Bak-deficient cells
Sun Aug 01 00:00:00 EDT 2010
Calpain and caspase processing of caspase-12 contribute to the ER stress-induced cell death pathway in differentiated PC12 cells.
Apoptosis : an international journal on programmed cell death
Martinez JA,Zhang Z,Svetlov SI,Hayes RL,Wang KK,Larner SF
MA3-414 was used in western blot to investigate the involvement of calpain and caspase 12 in the cell death induced by endoplasmic reticulum stress
Wed Dec 01 00:00:00 EST 2010
Subcellular rearrangement of hsp90-binding immunophilins accompanies neuronal differentiation and neurite outgrowth.
Journal of neurochemistry
Quintá HR,Maschi D,Gomez-Sanchez C,Piwien-Pilipuk G,Galigniana MD
Published figure using p23 monoclonal antibody (Product # MA3-414) in Immunocytochemistry
Mon Nov 01 00:00:00 EDT 2010
Subcellular rearrangement of hsp90-binding immunophilins accompanies neuronal differentiation and neurite outgrowth.
Journal of neurochemistry
Quintá HR,Maschi D,Gomez-Sanchez C,Piwien-Pilipuk G,Galigniana MD
Published figure using p23 monoclonal antibody (Product # MA3-414) in Immunocytochemistry
Mon Nov 01 00:00:00 EDT 2010
The hsp90-FKBP52 complex links the mineralocorticoid receptor to motor proteins and persists bound to the receptor in early nuclear events.
Molecular and cellular biology
Galigniana MD,Erlejman AG,Monte M,Gomez-Sanchez C,Piwien-Pilipuk G
MA3-414 was used in western blot to investigate the role of the heat shock protein 90-FKBP52 complex in the nucleus
Mon Mar 01 00:00:00 EST 2010
ATP binding to Hsp90 is sufficient for effective chaperoning of p53 protein.
The Journal of biological chemistry
Walerych D,Gutkowska M,Klejman MP,Wawrzynow B,Tracz Z,Wiech M,Zylicz M,Zylicz A
MA3-414 was used in western blot to study the mechanistic role of ATP in the Hsp90-p53 interaction.
Fri Oct 15 00:00:00 EDT 2010
Ordering of caspases in cells undergoing apoptosis by the intrinsic pathway.
Cell death and differentiation
Inoue S,Browne G,Melino G,Cohen GM
MA3-414 was used in western blot to investigate the hierarchical ordering of caspases in a more relevant physiological scenario
Wed Jul 01 00:00:00 EDT 2009
Expression of Hsp90 chaperone [corrected] proteins in human tumor tissue.
International journal of biological macromolecules
McDowell CL,Bryan Sutton R,Obermann WM
MA3-414 was used in immunohistochemistry to study the expression profiling of chaperone proteins in human tumor tissue samples
Thu Oct 01 00:00:00 EDT 2009
17-DMAG ameliorates polyglutamine-mediated motor neuron degeneration through well-preserved proteasome function in an SBMA model mouse.
Human molecular genetics
Tokui K,Adachi H,Waza M,Katsuno M,Minamiyama M,Doi H,Tanaka K,Hamazaki J,Murata S,Tanaka F,Sobue G
MA3-414 was used in western blot to study the effect of 17-(dimethylaminoethylamino)-17-demethoxygeldanamycin on polyglutamine-mediated motor neuron degeneration.
Sun Mar 01 00:00:00 EST 2009
Nuclear import of the glucocorticoid receptor-hsp90 complex through the nuclear pore complex is mediated by its interaction with Nup62 and importin beta.
Molecular and cellular biology
Echeverría PC,Mazaira G,Erlejman A,Gomez-Sanchez C,Piwien Pilipuk G,Galigniana MD
MA3-414 was used in immunoprecipitation to study the mechanism of nuclear import of the glucocorticoid receptor-hsp90 complex through the nuclear pore complex
Tue Sep 01 00:00:00 EDT 2009
Hsp90 regulates the Fanconi anemia DNA damage response pathway.
Blood
Oda T,Hayano T,Miyaso H,Takahashi N,Yamashita T
MA3-414 was used in immunoprecipitation to study the role of Hsp90 in regulating the Fanconi anemia DNA damage response pathway
Fri Jun 01 00:00:00 EDT 2007
Multiple 40-kDa heat-shock protein chaperones function in Tom70-dependent mitochondrial import.
Molecular biology of the cell
Bhangoo MK,Tzankov S,Fan AC,Dejgaard K,Thomas DY,Young JC
MA3-414 was used in western blot to investigate the roles of multiple 40-kDa heat-shock protein chaperones during the Tom70-dependent mitochondrial import.
Sat Sep 01 00:00:00 EDT 2007
Cytosolic prostaglandin E2 synthase (cPGES) expression is decreased in discrete cortical regions in psychiatric disease.
Brain research
Maida ME,Hurley SD,Daeschner JA,Moore AH,O'Banion MK
MA3-414 was used in western blot to investigate the change of expression of cytosolic prostaglandin E2 synthase in psychiatric patients
Fri Aug 04 00:00:00 EDT 2006
17-AAG, an Hsp90 inhibitor, ameliorates polyglutamine-mediated motor neuron degeneration.
Nature medicine
Waza M,Adachi H,Katsuno M,Minamiyama M,Sang C,Tanaka F,Inukai A,Doyu M,Sobue G
MA3-414 was used in western blot to investigate the role of 17-AAG in curing spinal and bulbar muscular atrophy as well as degradation of polyglutamine-expanded mutant AR
Sat Oct 01 00:00:00 EDT 2005
Expression and localization of adipophilin and perilipin in human fetal membranes: association with lipid bodies and enzymes involved in prostaglandin synthesis.
The Journal of clinical endocrinology and metabolism
Meadows JW,Pitzer B,Brockman DE,Myatt L
MA3-414 was used in immunohistochemistry to study the expression of adipophilin and perilipin in human fetal membranes at preterm and term.
Fri Apr 01 00:00:00 EST 2005
Rapid glucocorticoid receptor exchange at a promoter is coupled to transcription and regulated by chaperones and proteasomes.
Molecular and cellular biology
Stavreva DA,Müller WG,Hager GL,Smith CL,McNally JG
MA3-414 was used in immunocytochemistry to investigate the role of chaperones and proteasomes during glucocorticoid receptor exchange.
Thu Apr 01 00:00:00 EST 2004
Microsomal prostaglandin E synthase-1 is overexpressed in inflammatory bowel disease. Evidence for involvement of the transcription factor Egr-1.
The Journal of biological chemistry
Subbaramaiah K,Yoshimatsu K,Scherl E,Das KM,Glazier KD,Golijanin D,Soslow RA,Tanabe T,Naraba H,Dannenberg AJ
MA3-414 was used in western blot to study the effect of Egr-1-mediated transcription activation on mPGES-1 expression in inflammatory bowel disease .
Fri Mar 26 00:00:00 EST 2004
FK506 requires stimulation of the extracellular signal-regulated kinase 1/2 and the steroid receptor chaperone protein p23 for neurite elongation.
Neuro-Signals
Gold BG,Zhong YP
MA3-414 was used in immunocytochemistry to study the role of the ERK and steroid receptor chaperone protein p23 in the neurite elongation activity of FK506
Tue Jul 06 00:00:00 EDT 2004
Progesterone receptor deficient in chromatin binding has an altered cellular state.
The Journal of biological chemistry
Botos J,Xian W,Smith DF,Smith CL
MA3-414 was used in immunoprecipitation to analyze the altered cellular processing by comparing the composition and distribution of tPR and sPR complexes
Fri Apr 09 00:00:00 EDT 2004
The hsp90-related protein TRAP1 is a mitochondrial protein with distinct functional properties.
The Journal of biological chemistry
Felts SJ,Owen BA,Nguyen P,Trepel J,Donner DB,Toft DO
MA3-414 was used in immunoprecipitation to investigate the functional properties HSP90-related protein TRAP1 in mitochondria
Fri Feb 04 00:00:00 EST 2000
Active participation of Hsp90 in the biogenesis of the trimeric reovirus cell attachment protein sigma1.
The Journal of biological chemistry
Gilmore R,Coffey MC,Lee PW
MA3-414 was used in immunoprecipitation to demonstrate that chaperones play an important role in the regulation of general protein folding and of steroid receptor activation
Fri Jun 12 00:00:00 EDT 1998
