Thermo Scientific™
Tango™ GPR44 (CRTH2)-bla U2OS Cells
Tango™ GPR44-bla U2OS cells contain the human G protein coupled receptor 44 (GPR44) linked to a TEV protease site and Read more
Catalog number K1859
Price (USD)/ 1 vial
10,580.00
-
Price (USD)/ 1 vial
10,580.00
Tango™ GPR44 (CRTH2)-bla U2OS Cells
Catalog numberK1859
Price (USD)/ 1 vial
10,580.00
-
Tango™ GPR44-bla U2OS cells contain the human G protein coupled receptor 44 (GPR44) linked to a TEV protease site and a Gal4-VP16 transcription factor stably integrated into the Tango™ GPCR-bla U2OS parental cell line. This parental cell line stably expresses a beta-arrestin/TEV protease fusion protein and the beta-lactamase reporter gene under the control of a UAS response element. The Tango™ GPR44-bla U2OS cells have been functionally validated for Z' factor and EC50 concentrations of Indomethacin. In addition, Tango™ GPR44-bla U2OS cells have been tested for assay performance under variable conditions.
For Research Use Only. Not for use in diagnostic procedures.
Specifications
Accession NumberNM_004778
Assay EntryCell-based beta-arrestin recruitment
Cell StateDividing Cells
Cytoplasmic TailTail from GRPR GPCR
Detection MethodFluorescence
For Use With (Application)FRET
Human Protein ClassG-Protein Coupled Receptor (GPCR)
Population StatusSingle Cell Clone Origin
Product LineTango™
Quantity1 Vial
ReadoutEnd Point
Target EntryCRTH2, GPR44
Cell LineU2OS
System TypeTango™
Druggable TargetGPCR
Unit Size1 vial
Contents & Storage
Tango™ GPR44 (CRTH2)-bla U2OS cells are shipped on dry ice, 8 x 106 cells/vial. Store in liquid nitrogen immediately upon receipt, or thaw for immediate use.