Thermo Scientific™
Tango™ EDG3-bla U2OS Cells
Tango™ EDG3-bla U2OS cells contain the human Endothelial Differentiation Gene 3 (EDG3) linked to a TEV protease site and a Read more
Catalog number K1848
Price (USD)/ 8 x 106 cells⁄vial
10,580.00
-
Price (USD)/ 8 x 106 cells⁄vial
10,580.00
Tango™ EDG3-bla U2OS Cells
Catalog numberK1848
Price (USD)/ 8 x 106 cells⁄vial
10,580.00
-
Tango™ EDG3-bla U2OS cells contain the human Endothelial Differentiation Gene 3 (EDG3) linked to a TEV protease site and a Gal4-VP16 transcription factor stably integrated into the Tango™ GPCR-bla U2OS parental cell line. This parental cell line stably expresses a beta-arrestin/TEV protease fusion protein and the beta-lactamase reporter gene under the control of a UAS response element. The Tango™ EDG3-bla U2OS cells have been functionally validated for Z' factor and EC50 concentrations of S1P. In addition, Tango™ EDG3-bla U2OS cells have been tested for assay performance under variable conditions.
For Research Use Only. Not for use in diagnostic procedures.
Specifications
Accession NumberNM_005226.2
Assay EntryCell-based beta-arrestin recruitment
Cell StateDividing Cells
Cytoplasmic TailNative Tail
Detection MethodFluorescence
For Use With (Application)FRET
Human Protein ClassG-Protein Coupled Receptor (GPCR)
Population StatusPool of Stable Cells
Product LineTango™
Quantity8 x 106 Cells
ReadoutEnd Point
Reporter GeneBLA (Beta-Lactamase)
Target EntryEDG3
Cell LineU2OS
System TypeTango™
Druggable TargetGPCR
Unit Size8 x 106 cells⁄vial
Contents & Storage
Tango™ cell lines are shipped on dry ice. Store in liquid nitrogen immediately upon receipt, or thaw for immediate use.