Thermo Scientific™
Tango™ CXCR3-bla U2OS Cells
The Tango™ CXCR3-bla U2OS cells contain the human chemokine (C-X-C motif) receptor 3 (CXCR3) linked to a TEV protease site Read more
Catalog number K1829
Price (USD)/ 8 x 106 cells
10,580.00
-
Price (USD)/ 8 x 106 cells
10,580.00
Tango™ CXCR3-bla U2OS Cells
Catalog numberK1829
Price (USD)/ 8 x 106 cells
10,580.00
-
The Tango™ CXCR3-bla U2OS cells contain the human chemokine (C-X-C motif) receptor 3 (CXCR3) linked to a TEV protease site and a Gal4-VP16 transcription factor stably integrated into the Tango™ GPCR-bla U2OS parental cell line. This parental cell line stably expresses a beta-arrestin/TEV protease fusion protein and the beta-lactamase (bla) reporter gene under the control of a UAS response element.
The Tango™ CXCR3-bla U2OS cells are functionally validated for Z' and EC50 concentrations of I-TAC (CXCL11). In addition, Tango™ CXCR3-bla U2OS cells have been tested for assay performance under variable conditions. This data are found in the Validation & Assay Performance Summary.
For Research Use Only. Not for use in diagnostic procedures.
Specifications
Accession NumberNM_001504
Assay EntryCell-based beta-arrestin recruitment
Cell StateDividing Cells
Cytoplasmic TailNative Tail
Detection MethodFluorescence
For Use With (Application)FRET
Gene SymbolCXCR3
Human Protein ClassG-Protein Coupled Receptor (GPCR)
Population StatusSingle Cell Clone Origin
Product LineGeneBLAzer™, Tango™
Quantity8 x 106 Cells
ReadoutEnd Point
Target EntryCXCR3
TypeU2OS Cell
Cell LineU2OS
System TypeTango™
Druggable TargetGPCR
Unit Size8 x 106 cells
Contents & Storage
Contents:
K1829 Tango™ CXCR3-bla U2OS cells
(LiveBLAzer™-FRET B/G Loading Kit, Solution D and other materials are required separately; please refer to the protocol).
Includes:
• Tango™ CXCR3-bla U2OS cells
• Tango™ CXCR3-bla U2OS Assay Protocol
• Certificate of Analysis
Storage:
The Tango™ CXCR3-bla U2OS cells are shipped on dry ice and should be stored in liquid nitrogen immediately upon receipt.
K1829 Tango™ CXCR3-bla U2OS cells
(LiveBLAzer™-FRET B/G Loading Kit, Solution D and other materials are required separately; please refer to the protocol).
Includes:
• Tango™ CXCR3-bla U2OS cells
• Tango™ CXCR3-bla U2OS Assay Protocol
• Certificate of Analysis
Storage:
The Tango™ CXCR3-bla U2OS cells are shipped on dry ice and should be stored in liquid nitrogen immediately upon receipt.