Tango™ M4-bla U2OS Cells
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Thermo Scientific™

Tango™ M4-bla U2OS Cells

The Tango™ M4-bla U2OS cells contain the human Acetycholine (muscarinic) subtype 4 receptor (M4) linked to a TEV protease site  Read more
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Catalog number K1818
Price (USD)/ 8 x 106 cells
10,580.00
-
Add to cart
Price (USD)/ 8 x 106 cells
10,580.00
Add to cart
Tango™ M4-bla U2OS Cells
Catalog numberK1818
Price (USD)/ 8 x 106 cells
10,580.00
-
Add to cart

The Tango™ M4-bla U2OS cells contain the human Acetycholine (muscarinic) subtype 4 receptor (M4) linked to a TEV protease site and a Gal4-VP16 transcription factor stably integrated into the Tango™ GPCR-bla U2OS parental cell line. This parental cell line stably expresses a beta-arrestin/TEV protease fusion protein and the beta-lactamase (bla) reporter gene under the control of a UAS response element.

The Tango™ M4-bla U2OS cells are functionally validated for Z' and EC50 concentrations of Carbachol. In addition, Tango™ M4-bla U2OS cells have been tested for assay performance under variable conditions. These data are found in the Validation & Assay Performance Summary.

For Academic pricing please login or contact us at discoverysciences@invitrogen.com.

For Research Use Only. Not for use in diagnostic procedures.
Specifications
Accession NumberNM_000741
Assay EntryCell-based beta-arrestin recruitment
Cell StateDividing Cells
Cytoplasmic TailNative Tail
Detection MethodFluorescence
For Use With (Application)FRET
Gene SymbolM4
Human Protein ClassG-Protein Coupled Receptor (GPCR)
Population StatusSingle Cell Clone Origin
Product LineGeneBLAzer™, Tango™
Quantity8 x 106 Cells
ReadoutEnd Point
Target EntryM4
TypeU2OS Cell
Cell LineU2OS
System TypeTango™
Druggable TargetGPCR
Unit Size8 x 106 cells
Contents & Storage
LiveBLAzer™-FRET B/G Loading Kit, Solution D and other materials are required separately; please refer to the protocol.

Includes:
• Tango™ M4-bla U2OS cells
• Tango™ M4-bla U2OS Assay Protocol
• Certificate of Analysis

The Tango™ M4-bla U2OS cells are shipped on dry ice and should be stored in liquid nitrogen immediately upon receipt.