GeneBLAzer™ BDKRB1-NFAT-bla CHO-K1 Cells
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Thermo Scientific™

GeneBLAzer™ BDKRB1-NFAT-bla CHO-K1 Cells

GeneBLAzer™ BDKRB1-NFAT-bla CHO-K1 cells contain the human Bradykinin Receptor 1 (BDKBR1) stably integrated into the CellSensor™ NFAT-bla CHO-K1 cell line.  Read more
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Catalog number K1734
Price (USD)/ 2 × 10^6 cells
10,580.00
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Add to cart
Price (USD)/ 2 × 10^6 cells
10,580.00
Add to cart
GeneBLAzer™ BDKRB1-NFAT-bla CHO-K1 Cells
Catalog numberK1734
Price (USD)/ 2 × 10^6 cells
10,580.00
-
Add to cart

GeneBLAzer™ BDKRB1-NFAT-bla CHO-K1 cells contain the human Bradykinin Receptor 1 (BDKBR1) stably integrated into the CellSensor™ NFAT-bla CHO-K1 cell line. CellSensor™ NFAT-bla CHO-K1 cells (Cat. No. K1534) contain a beta-lactamase reporter gene under control of the Nuclear Factor of Activated T-cells (NFAT) response element.

The GeneBLAzer™ BDKRB1-NFAT-bla CHO-K1 cells are functionally validated for Z' and EC50 concentrations of [Lys-des-Arg9]-Bradykinin. In addition, GeneBLAzer™ BDKRB1-NFAT-bla CHO-K1 cells have been tested for assay performance under variable conditions. These data are found in the Validation & Assay Performance Summary.

The Bradykinin-BDKRB1 receptor has been implicated in inflammation and pain. Preclinical evidence demonstrates that interruption of BDKRB1 receptor function causes analgesia under a variety of conditions and has been well established using selective antagonists and genetically modified mice.

For Academic pricing please login or contact us at discoverysciences@invitrogen.com.

For Research Use Only. Not for use in diagnostic procedures.
Specifications
Accession NumberNM_000710
Assay EntryCell-based beta lactamase reporter gene
Cell StateDividing Cells
Detection MethodFluorescence
For Use With (Application)FRET
Gene SymbolBDKRB1
Population StatusSingle Cell Clone Origin
Product LineGeneBLAzer™
Quantity2 x 106 Cells
Reporter GeneBLA (Beta-Lactamase)
Target EntryBDKRB1
Cell LineCHO-K1
System TypeGeneBLAzer™
Druggable TargetGPCR
Unit Size2 × 10^6 cells
Contents & Storage
LiveBLAzer™-FRET B/G Loading Kit, Solution D and other materials are required separately; please refer to the protocol.

Includes:
• GeneBLAzer™ BDKRB1-NFAT-bla CHO-K1 cells
• GeneBLAzer™ BDKRB1-NFAT-bla CHO-K1 Assay Protocol
• Certificate of Analysis

The GeneBLAzer™ BDKRB1-NFAT-bla CHO-K1 cells are shipped on dry ice and should be stored in liquid nitrogen immediately upon receipt.