GeneBLAzer™ P2RY11-NFAT-bla CHO-K1 Cells
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Thermo Scientific™

GeneBLAzer™ P2RY11-NFAT-bla CHO-K1 Cells

GeneBLAzer™ P2RY11-NFAT-bla CHO-K1 cells contain the human Purinergic receptor P2, G protein-coupled, 11 (P2RY11) stably integrated into the CellSensor™ NFAT-bla  Read more
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Catalog number K1729
Price (USD)/ 2 x 106 cells
10,580.00
-
Add to cart
Price (USD)/ 2 x 106 cells
10,580.00
Add to cart
GeneBLAzer™ P2RY11-NFAT-bla CHO-K1 Cells
Catalog numberK1729
Price (USD)/ 2 x 106 cells
10,580.00
-
Add to cart

GeneBLAzer™ P2RY11-NFAT-bla CHO-K1 cells contain the human Purinergic receptor P2, G protein-coupled, 11 (P2RY11) stably integrated into the CellSensor™ NFAT-bla CHO-K1 cell line. CellSensor™ NFAT-bla CHO-K1 cells (Cat. No. K1534) contain a beta-lactamase reporter gene under control of the Nuclear Factor of Activated T-cells (NFAT) response element.

The GeneBLAzer™ P2RY11-NFAT-bla CHO-K1 cells are functionally validated for Z' and EC50 concentrations of ATP. In addition, GeneBLAzer™ P2RY11-NFAT-bla CHO-K1 cells have been tested for assay performance under variable conditions. These data are found in the Validation & Assay Performance Summary.

P2RY11 expression is broadly distributed and has been found in the brain, pituitary, lymphocytes, spleen, intestines, macrophages, lung, stomach, adipose tissue, pancreas, kidney, prostate, heart, placenta, liver, and skeletal muscle. Differentiation of human promyelocytic HL60 cells and maturation of monocyte-derived dendritic cells have been shown to be mediated by ATP activation of P2RY11.

For Academic pricing please login or contact us at discoverysciences@invitrogen.com.

For Research Use Only. Not for use in diagnostic procedures.
Specifications
Accession NumberNM_002566.4
Assay EntryCell-based beta lactamase reporter gene
Cell StateDividing Cells
Detection MethodFluorescence
For Use With (Application)FRET
Gene SymbolP2RY11
Population StatusSingle Cell Clone Origin
Product LineGeneBLAzer™
Quantity2 x 106 Cells
Reporter GeneBLA (Beta-Lactamase)
Target EntryP2RY11
Cell LineCHO-K1
System TypeGeneBLAzer™
Druggable TargetGPCR
Unit Size2 x 106 cells
Contents & Storage
LiveBLAzer™-FRET B/G Loading Kit, Solution D and other materials are required separately; please refer to the protocol.

Includes:
• GeneBLAzer™ P2RY11-NFAT-bla CHO-K1 cells
• GeneBLAzer™ P2RY11-NFAT-bla CHO-K1 Assay Protocol
• Certificate of Analysis

The GeneBLAzer™ P2RY11-NFAT-bla CHO-K1 cells are shipped on dry ice and should be stored in liquid nitrogen immediately upon receipt.