GeneBLAzer™ ENDRB-NFAT-bla HEK 293T Cells
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Thermo Scientific™

GeneBLAzer™ ENDRB-NFAT-bla HEK 293T Cells

GeneBLAzer™ EDNRB-NFAT-bla HEK293T cells contain the human Endothelin Type B Recpetor (EDNRB) stably integrated into the CellSensor™ NFAT-bla HEK293T cell  Read more
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Catalog number K1727
Price (USD)/ 2 x 106 cells
10,580.00
-
Add to cart
Price (USD)/ 2 x 106 cells
10,580.00
Add to cart
GeneBLAzer™ ENDRB-NFAT-bla HEK 293T Cells
Catalog numberK1727
Price (USD)/ 2 x 106 cells
10,580.00
-
Add to cart

GeneBLAzer™ EDNRB-NFAT-bla HEK293T cells contain the human Endothelin Type B Recpetor (EDNRB) stably integrated into the CellSensor™ NFAT-bla HEK293T cell line. CellSensor™ NFAT-bla HEK293T cells (Cat. No. K1538) contain a beta-lactamase reporter gene under control of the Nuclear Factor of Activated T-cells (NFAT) response element.

The GeneBLAzer™ EDNRB-NFAT-bla HEK293T cells are functionally validated for Z' and EC50 concentrations of ET-1. In addition, GeneBLAzer™ EDNRB-NFAT-bla HEK293T cells have been tested for assay performance under variable conditions. These data are found in the Validation & Assay Performance Summary.

The ENDRB receptor mediates signaling of endothelin proteins that regulate several critical biological processes, including the development and function of blood vessels, the production of certain hormones, and the stimulation of cell growth and division. Defects in EDNRB mediated signaling have been implicated in a wide range of diseases, including cancer, hypertension and cardiovascular disorders.

For Academic pricing please login or contact us at discoverysciences@invitrogen.com.

For Research Use Only. Not for use in diagnostic procedures.
Specifications
Accession NumberNM_000115.1
Assay EntryCell-based beta lactamase reporter gene
Cell StateDividing Cells
Detection MethodFluorescence
For Use With (Application)FRET
Gene SymbolEDNRB
Population StatusSingle Cell Clone Origin
Product LineGeneBLAzer™
Quantity2 x 106 Cells
Reporter GeneBLA (Beta-Lactamase)
Target EntryEDNRB
TypeCell Line
Cell Line293T (HEK)
System TypeGeneBLAzer™
Druggable TargetGPCR
Unit Size2 x 106 cells
Contents & Storage
LiveBLAzer™-FRET B/G Loading Kit, Solution D and other materials are required separately; please refer to the protocol.

Includes:
• GeneBLAzer™ EDNRB-NFAT-bla HEK293T cells
• GeneBLAzer™ EDNRB-NFAT-bla HEK293T Assay Protocol
• Certificate of Analysis

The GeneBLAzer™ GeneBLAzer™ EDNRB-NFAT-bla HEK293T cells are shipped on dry ice and should be stored in liquid nitrogen immediately upon receipt.