CellSensor™ NFKB-bla Freestyle™ HEK293F Cell Line
Product Image
Thermo Scientific™

CellSensor™ NFKB-bla Freestyle™ HEK293F Cell Line

Nuclear Factor kappaB (NFκB) signaling regulates genes involved in apoptosis, viral defense, cancer, inflammation, and autoimmune disease. The CellSensor™ NFκB-bla  Read more
Have Questions?
Catalog number K1663
Price (USD)/ 1 vial
10,580.00
-
Add to cart
Price (USD)/ 1 vial
10,580.00
Add to cart
CellSensor™ NFKB-bla Freestyle™ HEK293F Cell Line
Catalog numberK1663
Price (USD)/ 1 vial
10,580.00
-
Add to cart

Nuclear Factor kappaB (NFκB) signaling regulates genes involved in apoptosis, viral defense, cancer, inflammation, and autoimmune disease. The CellSensor™ NFκB-bla FreeStyle™ 293F Cell Line is responsive to tumor necrosis factor alpha (TNFα) and can be used to probe the NFκB signaling pathway. This cell line was validated for DMSO tolerance, incubation time with stimulant and substrate loading conditions. The CellSensor™ NFκB-bla FreeStyle™ 293F Cell Line contains a beta-lactamase reporter gene under the control of NFκB response element. The construct was transduced into FreeStyle™ 293F cells by lentivirus. This cell line is a pool isolated for response to TNFα by flow cytometry. It responds to agonist treatment as expected from literature. Academic and non-profit customers, please inquire for special pricing.

For Research Use Only. Not for use in diagnostic procedures.
Specifications
Assay EntryCell-based beta lactamase reporter gene
Cell StateDividing Cells
Product LineCellSensor™
Quantity1 Vial
Target EntryTNF alpha, NIK, TLR, I kappa B, IRAK, IKK, NF-kappa B pathway
System TypeCellSensor™
Druggable TargetSignaling Pathway
Unit Size1 vial
Contents & Storage
CellSensor™ Cell Lines are shipped on dry ice. Store in liquid nitrogen immediately upon receipt, or thaw for immediate use.