Product References
A nonredundant role for T cell-derived interleukin 22 in antibacterial defense of colonic crypts.
Immunity
Zindl CL,Witte SJ,Laufer VA,Gao M,Yue Z,Janowski KM,Cai B,Frey BF,Silberger DJ,Harbour SN,Singer JR,Turner H,Lund FE,Vallance BA,Rosenberg AF,Schoeb TR,Chen JY,Hatton RD,Weaver CT
A-11090 was used in Immunohistochemistry to demonstrate spatiotemporal differences in the production and action of IL-22 by ILCs and T cells during infection and reveal an indispensable role for IL-22-producing T cells in the protection of the intestinal crypts.
Tue Mar 08 00:00:00 EST 2022
Long-term maintenance of lung resident memory T cells is mediated by persistent antigen.
Mucosal immunology
Uddbäck I,Cartwright EK,Schøller AS,Wein AN,Hayward SL,Lobby J,Takamura S,Thomsen AR,Kohlmeier JE,Christensen JP
A-11090 was used in Immunocytochemistry to show persistent antigen is needed to maintain lung resident memory T cells and thus long lived immunity to influenza virus.
Fri Jan 01 00:00:00 EST 2021
Evidence for a functional interaction of WNT10A and EBF1 in male-pattern baldness.
PloS one
Hochfeld LM,Bertolini M,Broadley D,Botchkareva NV,Betz RC,Schoch S,Nöthen MM,Heilmann-Heimbach S
A-11090 was used in Immunohistochemistry to further elucidate the regulatory architecture of the male pattern baldness risk locus on chromosome 2q35.
Thu Nov 18 00:00:00 EST 2021
MRE11-dependent instability in mitochondrial DNA fork protection activates a cGAS immune signaling pathway.
Science advances
Luzwick JW,Dombi E,Boisvert RA,Roy S,Park S,Kunnimalaiyaan S,Goffart S,Schindler D,Schlacher K
A-11090 was used in Immunocytochemistry-immunofluorescence to establish a previously unknown molecular pathway for mtDNA replication stability and reveal a molecular handle to control mtDNA-dependent cGAS activation by inhibiting MRE11 nuclease.
Fri Dec 17 00:00:00 EST 2021
Neuronal excitatory-to-inhibitory balance is altered in cerebral organoid models of genetic neurological diseases.
Molecular brain
Foliaki ST,Schwarz B,Groveman BR,Walters RO,Ferreira NC,Orrù CD,Smith A,Wood A,Schmit OM,Freitag P,Yuan J,Zou W,Bosio CM,Carroll JA,Haigh CL
A-11090 was used in Immunohistochemistry to explore neuro-physiological properties using cerebral organoids derived from fibroblasts of individuals with confirmed genetic mutations including PRNPE200K, trisomy 21 (T21), and LRRK2G2019S, which are associated with Creutzfeldt Jakob disease, Down Syndrome, and Parkinson's disease.
Mon Oct 11 00:00:00 EDT 2021
Neuronal excitatory-to-inhibitory balance is altered in cerebral organoid models of genetic neurological diseases.
Molecular brain
Foliaki ST,Schwarz B,Groveman BR,Walters RO,Ferreira NC,Orrù CD,Smith A,Wood A,Schmit OM,Freitag P,Yuan J,Zou W,Bosio CM,Carroll JA,Haigh CL
A-11090 was used in Immunohistochemistry to explore neuro-physiological properties using cerebral organoids derived from fibroblasts of individuals with confirmed genetic mutations including PRNPE200K, trisomy 21 (T21), and LRRK2G2019S, which are associated with Creutzfeldt Jakob disease, Down Syndrome, and Parkinson's disease.
Mon Oct 11 00:00:00 EDT 2021
Abnormal Eating Patterns Cause Circadian Disruption and Promote Alcohol-Associated Colon Carcinogenesis.
Cellular and molecular gastroenterology and hepatology
Bishehsari F,Engen PA,Voigt RM,Swanson G,Shaikh M,Wilber S,Naqib A,Green SJ,Shetuni B,Forsyth CB,Saadalla A,Osman A,Hamaker BR,Keshavarzian A,Khazaie K
A-11090 was used in Immunohistochemistry to test the hypothesis that eating during or around physiologic rest time, a common habit in modern society, causes circadian rhythm disruption (CRD) and investigate the mechanisms by which it promotes alcohol-associated colon carcinogenesis.
Wed May 05 00:00:00 EDT 2021
Pgc suppresses the zygotically acting RNA decay pathway to protect germ plasm RNAs in the Drosophila embryo.
Development (Cambridge, England)
Hanyu-Nakamura K,Matsuda K,Cohen SM,Nakamura A
A-11090 was used in Immunohistochemistry-wholemount to investigate if independently evolved mechanisms are used to silence miRNAs during germ cell specification.
Thu Apr 04 00:00:00 EDT 2019
Curcumin reduces renal damage associated with rhabdomyolysis by decreasing ferroptosis-mediated cell death.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Guerrero-Hue M,García-Caballero C,Palomino-Antolín A,Rubio-Navarro A,Vázquez-Carballo C,Herencia C,Martín-Sanchez D,Farré-Alins V,Egea J,Cannata P,Praga M,Ortiz A,Egido J,Sanz AB,Moreno JA
A-11090 was used in Immunohistochemistry-immunofluorescence to investigate whether ferroptosis is associated with rhabdomyolysis-mediated renal damage.
Thu Aug 01 00:00:00 EDT 2019
LSD1 Cooperates with Noncanonical NF-κB Signaling to Regulate Marginal Zone B Cell Development.
Journal of immunology (Baltimore, Md. : 1950)
Haines RR,Scharer CD,Lobby JL,Boss JM
A-11090 was used in Immunohistochemistry to show that during the developing of marginal zone B cells, LSD1-mediated epigenetic modulation of the noncanonical NF-κB signaling pathway is an essential process.
Tue Oct 01 00:00:00 EDT 2019
B cell activation and plasma cell differentiation are inhibited by de novo DNA methylation.
Nature communications
Barwick BG,Scharer CD,Martinez RJ,Price MJ,Wein AN,Haines RR,Bally APR,Kohlmeier JE,Boss JM
A-11090 was used in Immunohistochemistry-immunofluorescence to show that de novo DNA methylation limits B cell activation, represses the plasma cell chromatin state, and regulates plasma cell differentiation.
Tue May 15 00:00:00 EDT 2018
Differential requirement of kindlin-3 for T cell progenitor homing to the non-vascularized and vascularized thymus.
eLife
Moretti FA,Klapproth S,Ruppert R,Margraf A,Weber J,Pick R,Scheiermann C,Sperandio M,Fässler R,Moser M
A-11090 was used in Immunohistochemistry-immunofluorescence to demonstrate that kindlin-3 is dispensable for integrin-mediated T-cell progenitor adhesion and signalling at low and indispensable at high shear forces.
Thu Sep 06 00:00:00 EDT 2018
Orexinergic Modulation of Spinal Motor Activity in the Neonatal Mouse Spinal Cord.
eNeuro
Biswabharati S,Jean-Xavier C,Eaton SEA,Lognon AP,Brett R,Hardjasa L,Whelan PJ
A-11090 was used in Immunohistochemistry-immunofluorescence to study the network actions of orexin during the first week of development.
Fri Apr 19 00:00:00 EDT 2019
Pallidin protein in neurodevelopment and its relation to the pathogenesis of schizophrenia.
Molecular medicine reports
Shi Q,Li C,Li K,Liu Q
A11090 was used in immunocytochemistry to test whether pallidin and p38 play a role in neural system development and the pathogenesis of schizophrenia
Wed Feb 01 00:00:00 EST 2017
Interleukin-17 limits hypoxia-inducible factor 1α and development of hypoxic granulomas during tuberculosis.
JCI insight
Domingo-Gonzalez R,Das S,Griffiths KL,Ahmed M,Bambouskova M,Gopal R,Gondi S,Muñoz-Torrico M,Salazar-Lezama MA,Cruz-Lagunas A,Jiménez-Álvarez L,Ramirez-Martinez G,Espinosa-Soto R,Sultana T,Lyons-Weiler J,Reinhart TA,Arcos J,de la Luz Garcia-Hernandez M,Mastrangelo MA,Al-Hammadi N,Townsend R,Balada-Llasat JM,Torrelles JB,Kaplan G,Horne W,Kolls JK,Artyomov MN,Rangel-Moreno J,Zúñiga J,Khader SA
A-11090 was used in Immunohistochemistry to highlight a potentially novel role for IL-17 in limiting the development of hypoxic necrotic granulomas and reducing disease severity in tuberculosis.
Thu Oct 05 00:00:00 EDT 2017
Live imaging reveals the dynamics and regulation of mitochondrial nucleoids during the cell cycle in Fucci2-HeLa cells.
Scientific reports
Sasaki T,Sato Y,Higashiyama T,Sasaki N
A-11090 was used in Immunocytochemistry-immunoflourescence to analyse the regulation of maintaining mitochondrial nucleoids in the cell cycle.
Tue Sep 12 00:00:00 EDT 2017
Pneumocystis-Driven Inducible Bronchus-Associated Lymphoid Tissue Formation Requires Th2 and Th17 Immunity.
Cell reports
Eddens T,Elsegeiny W,Garcia-Hernadez ML,Castillo P,Trevejo-Nunez G,Serody K,Campfield BT,Khader SA,Chen K,Rangel-Moreno J,Kolls JK
A-11090 was used in immunohistochemistry (paraffin) to develop a model for fungal-mediated inducible bronchus-associated lymphoid tissue.
Tue Mar 28 00:00:00 EDT 2017
Epithelial Transforming Growth Factor-β Signaling Does Not Contribute to Liver Fibrosis but Protects Mice From Cholangiocarcinoma.
Gastroenterology
Mu X,Pradere JP,Affò S,Dapito DH,Friedman R,Lefkovitch JH,Schwabe RF
A-11090 was used in Immunohistochemistry to determine the contribution of epithelial transforming growth factor-Β signalling to hepatic fibrogenesis and carcinogenesis.
Tue Mar 01 00:00:00 EST 2016
The Residual Innate Lymphoid Cells in NFIL3-Deficient Mice Support Suboptimal Maternal Adaptations to Pregnancy.
Frontiers in immunology
Boulenouar S,Doisne JM,Sferruzzi-Perri A,Gaynor LM,Kieckbusch J,Balmas E,Yung HW,Javadzadeh S,Volmer L,Hawkes DA,Phillips K,Brady HJ,Fowden AL,Burton GJ,Moffett A,Colucci F
A-11090 was used in immunohistochemistry - paraffin section to characterize the support of suboptimal maternal adpatations to pregnancy due to residual innate lymphoid cells in NFIL3-deficient mice
Mon Feb 29 00:00:00 EST 2016
CD163-Macrophages Are Involved in Rhabdomyolysis-Induced Kidney Injury and May Be Detected by MRI with Targeted Gold-Coated Iron Oxide Nanoparticles.
Theranostics
Rubio-Navarro A,Carril M,Padro D,Guerrero-Hue M,Tarín C,Samaniego R,Cannata P,Cano A,Villalobos JM,Sevillano ÁM,Yuste C,Gutiérrez E,Praga M,Egido J,Moreno JA
A-11090 was used in Immunohistochemistry to demonstrate that CD163 is present in both human and experimental rhabdomyolysis-induced acute kidney injury.
Mon Oct 16 00:00:00 EDT 2017
Mechanisms of Amplified Arteriogenesis in Collateral Artery Segments Exposed to Reversed Flow Direction.
Arteriosclerosis, thrombosis, and vascular biology
Heuslein JL,Meisner JK,Li X,Song J,Vincentelli H,Leiphart RJ,Ames EG,Blackman BR,Blackman BR,Price RJ
A-11090 was used in Immunohistochemistry-immunofluorescence to determine if reversed flow direction in collateral artery segments differentially regulates endothelial cell signalling and arteriogenesis.
Sun Nov 01 00:00:00 EDT 2015
Human enteric neurons: morphological, electrophysiological, and neurochemical identification.
Neurogastroenterology and motility
Carbone SE,Jovanovska V,Nurgali K,Brookes SJ
A-11090 was used in Immunohistochemistry to report a method to combine intracellular recording with simultaneous morphological identification of neurons in the intact myenteric plexus of human colon ex vivo.
Mon Dec 01 00:00:00 EST 2014
Nanoparticles that sense thrombin activity as synthetic urinary biomarkers of thrombosis.
ACS nano
Lin KY,Kwong GA,Warren AD,Wood DK,Bhatia SN
A-11090 was used in immunohistochemistry to describe a method to detect thrombi in living animals
Tue Oct 22 00:00:00 EDT 2013
Epiblast integrity requires CLASP and Dystroglycan-mediated microtubule anchoring to the basal cortex.
The Journal of cell biology
Nakaya Y,Sukowati EW,Sheng G
A-11090 was used in immunohistochemistry to study how integrity of epiblasts requires dystroglycan-mediated mictrotubule anchoring to the basal cortex and CLASP
Mon Aug 19 00:00:00 EDT 2013
SDF-1α in glycan nanoparticles exhibits full activity and reduces pulmonary hypertension in rats.
Biomacromolecules
Yin T,Bader AR,Hou TK,Maron BA,Kao DD,Qian R,Kohane DS,Handy DE,Loscalzo J,Zhang YY
Published figure using Fluorescein/Oregon Green polyclonal antibody (Product # A-11090) in Immunocytochemistry
Mon Nov 11 00:00:00 EST 2013
Exosome-like nanoparticles from intestinal mucosal cells carry prostaglandin E2 and suppress activation of liver NKT cells.
Journal of immunology (Baltimore, Md. : 1950)
Deng ZB,Zhuang X,Ju S,Xiang X,Mu J,Liu Y,Jiang H,Zhang L,Mobley J,McClain C,Feng W,Grizzle W,Yan J,Miller D,Kronenberg M,Zhang HG
A-11090 was used in Immunocytochemistry-immunoflourescence to demonstrate that intestinal, mucus-derived, exosome-like nanoparticles migrate to the liver where they induce NKT cell anergy.
Mon Apr 01 00:00:00 EDT 2013
Immunofluorescence protects RNA signals in simultaneous RNA-DNA FISH.
Experimental cell research
Lai LT,Lee PJ,Zhang LF
A-11090 was used in Immunohistochemistry to show that the improved method of simultaneous RNA-DNA FISH is reliable and time-efficient.
Fri Feb 01 00:00:00 EST 2013
Neonatal irradiation sensitizes mice to delayed pulmonary challenge.
Radiation research
Johnston CJ,Manning CM,Rangel-Moreno J,Randall TD,Hernady E,Finkelstein JN,Williams JP
A-11090 was used in Immunohistochemistry on paraffin embedded tissues to suggest that radiation injury during early life may affect the lung's response to a subsequent pathogenic aerial challenge.
Mon Apr 01 00:00:00 EDT 2013
Inducible tertiary lymphoid structures, autoimmunity, and exocrine dysfunction in a novel model of salivary gland inflammation in C57BL/6 mice.
Journal of immunology (Baltimore, Md. : 1950)
Bombardieri M,Barone F,Lucchesi D,Nayar S,van den Berg WB,Proctor G,Buckley CD,Pitzalis C
A-11090 was used in Immunocytochemistry-immunoflourescence to develop a novel murine model of inducible ectopic lymphoid tissue formation, breach of humoural self-tolerance, and salivary hypofunction.
Mon Oct 01 00:00:00 EDT 2012
Tumor necrosis factor receptor-associated factor (TRAF) 2 controls homeostasis of the colon to prevent spontaneous development of murine inflammatory bowel disease.
The Journal of biological chemistry
Piao JH,Hasegawa M,Heissig B,Hattori K,Takeda K,Iwakura Y,Okumura K,Inohara N,Nakano H
A-11090 was used in Immunofluorescence in immunohistochemistry on frozen tissues to demonstrate that tumour necrosis factor receptor-associated factor (Traf)2(-/-) mice spontaneously developed severe colitis and succumbed within 3 weeks after birth.
Fri May 20 00:00:00 EDT 2011
Soluble forms of VEGF receptor-1 and -2 promote vascular maturation via mural cell recruitment.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Lorquet S,Berndt S,Blacher S,Gengoux E,Peulen O,Maquoi E,Noël A,Foidart JM,Munaut C,Péqueux C
A-11090 was used in Immunocytochemistry to study the mechanisms regulating physiological and pathological angiogenesis and vessel stabilisation.
Fri Oct 01 00:00:00 EDT 2010
Alkylation damage causes MMR-dependent chromosomal instability in vertebrate embryos.
Nucleic acids research
Feitsma H,Akay A,Cuppen E
A-11090 was used in immunocytochemistry to analyze the cause of MMR-dependent chromosomal instability in vertebrate embryos due to alkylation damage
Tue Jul 01 00:00:00 EDT 2008
In vivo imaging of germinal centres reveals a dynamic open structure.
Nature
Schwickert TA,Lindquist RL,Shakhar G,Livshits G,Skokos D,Kosco-Vilbois MH,Dustin ML,Nussenzweig MC
A-11090 was used in immunohistochemistry - frozen section to visualize B cells in lymph node germinal centers in vivo
Thu Mar 01 00:00:00 EST 2007
Pancreatic acinar cells express vesicle-associated membrane protein 2- and 8-specific populations of zymogen granules with distinct and overlapping roles in secretion.
The Journal of biological chemistry
Weng N,Thomas DDH,Groblewski GE
A-11090 was used in immunocytochemistry to investigate the involvement of vesicle-associated membrane protein 2 and 8 in the secretory pathway
Fri Mar 30 00:00:00 EDT 2007
Immature dendritic cell-derived exosomes can mediate HIV-1 trans infection.
Proceedings of the National Academy of Sciences of the United States of America
Wiley RD,Gummuluru S
A-11090 was used in immunocytochemistry to report that HIV-1 particles captured by dendritic cells are transmitted to T cells by exocytosis without de novo infection
Tue Jan 17 00:00:00 EST 2006
Functional human telomeres are recognized as DNA damage in G2 of the cell cycle.
Molecular cell
Verdun RE,Crabbe L,Haggblom C,Karlseder J
A-11090 was used in Immunocytochemistry-immunoflourescence to study the importance of proteins involved in the DNA damage response, for telomere function.
Wed Nov 23 00:00:00 EST 2005
Kinesin I-dependent cortical exclusion restricts pole plasm to the oocyte posterior.
Nature cell biology
Cha BJ,Serbus LR,Koppetsch BS,Theurkauf WE
A-11090 was used in immunohistochemistry to study how oskar mRNA associates with the posterior pole
Thu Aug 01 00:00:00 EDT 2002
Analysis of minimal sample volumes from head and neck cancer by laser scanning cytometry.
Onkologie
Gerstner AO,Machlitt J,Laffers W,Tárnok A,Bootz F
A-11090 was used in Sample Preparation to suggest that the analysis of hypocellular specimens by LSC may have a role in routine clinical work, especially in tumours that are not accessible for open biopsy such as those of the parotid gland or the larynx.
Fri Feb 01 00:00:00 EST 2002
In vivo analysis of Drosophila bicoid mRNA localization reveals a novel microtubule-dependent axis specification pathway.
Cell
Cha BJ,Koppetsch BS,Theurkauf WE
A-11090 was used in immunohistochemistry to assess the revelation of a novel microtubule-dependent axis specification pathway by in vivo analysis of Drosophila bicoid mRNA localization
Fri Jul 13 00:00:00 EDT 2001
The CRE/CREB pathway is transiently expressed in thalamic circuit development and contributes to refinement of retinogeniculate axons.
Neuron
Pham TA,Rubenstein JL,Silva AJ,Storm DR,Stryker MP
A-11090 was used in immunohistochemistry to analyze transient expression in thalamic circuit development and contribution to refinement of retinogeniculate axons of the CRE/CREB pathway
Thu Aug 16 00:00:00 EDT 2001
A bead-based method for multiplexed identification and quantitation of DNA sequences using flow cytometry.
Applied and environmental microbiology
Spiro A,Lowe M,Brown D
A-11090 was used to develop a new multiplexed bead-based method to identify specific sequences in heterogeneous mixtures of DNA sequences
Sun Oct 01 00:00:00 EDT 2000
Molecular and biochemical characterization of a serine proteinase predominantly expressed in the medulla oblongata and cerebellar white matter of mouse brain.
The Journal of biological chemistry
Matsui H,Kimura A,Yamashiki N,Moriyama A,Kaya M,Yoshida I,Takagi N,Takahashi T
A-11090 was used in immunocytochemistry to isolate and characterize mouse brain serine proteinase
Fri Apr 14 00:00:00 EDT 2000
Assembly of the nuclear transcription and processing machinery: Cajal bodies (coiled bodies) and transcriptosomes.
Molecular biology of the cell
Gall JG,Bellini M,Wu Z,Murphy C
A-11090 was used in immunocytochemistry to determine the distribution of RNA transcription and processing factors in the amphibian oocyte nucleus or germinal vesicle
Wed Dec 01 00:00:00 EST 1999
