Product References
Electroacupuncture Attenuates Fibromyalgia Pain via Toll-like Receptor 4 in the Mouse Brain.
Life (Basel, Switzerland)
Lai PC,Yen CM,Lin MC,Chen YH,Liao HY,Huang YW,Lin YW
44-684G was used in Western Blotting to show that inflammation can activate the TLR4 pathway and provided new possible therapeutic targets for FM pain.
Thu May 11 00:00:00 EDT 2023
EphA3 targeted by miR-3666 contributes to melanoma malignancy via activating ERK1/2 and p38 MAPK pathways.
Open medicine (Warsaw, Poland)
Ming D,Ma J
44-684G was used in Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot to conclude that miR-3666 downregulated EphA3 expression and retarded melanoma malignancy via inactivating ERK1/2 and p38 MAPK pathways.
Tue Jan 03 00:00:00 EST 2023
CoQ10 augments candesartan protective effect against tourniquet-induced hind limb ischemia-reperfusion: Involvement of non-classical RAS and ROS pathways.
Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society
Awad AS,Nour El-Din M,Kamel R
44-684G was used in Western Blotting to show the impact of CoQ10 on skeletal muscle renin-angiotensin system in rats.
Thu Jul 01 00:00:00 EDT 2021
CoQ10 augments candesartan protective effect against tourniquet-induced hind limb ischemia-reperfusion: Involvement of non-classical RAS and ROS pathways.
Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society
Awad AS,Nour El-Din M,Kamel R
44-684G was used in Western Blotting to show the impact of CoQ10 on skeletal muscle renin-angiotensin system in rats.
Thu Jul 01 00:00:00 EDT 2021
Downregulation of FPR1 abates lipopolysaccharide-induced inflammatory injury and apoptosis by upregulating MAPK signaling pathway in murine chondrogenic ATDC5 cells.
Allergologia et immunopathologia
Chen H,Zhang L
44-684G was used in Western Blot to reveal that FPR1 was highly expressed in LPS-induced chondrocytes ATDC5, and the downregulation of FPR1 abated the inflammatory response and apoptosis of LPS-ATDC5 cells by regulating the MAPK signaling pathway.
Wed Feb 09 00:00:00 EST 2022
Lotus leaf flavonoids induce apoptosis of human lung cancer A549 cells through the ROS/p38 MAPK pathway.
Biological research
Jia XB,Zhang Q,Xu L,Yao WJ,Wei L
44-684G was used in Western Blotting to verify the effect of LLF on apoptosis in these cells through the ROS/p38 MAPK pathway.
Tue Mar 02 00:00:00 EST 2021
Evidence for acupoint catgut embedding treatment and TRPV1 gene deletion increasing weight control in murine model.
International journal of molecular medicine
Inprasit C,Huang YC,Lin YW
44-684G was used in Western Blotting to show body weight maintenance may be modulated by calcium ion channel TRPV1.
Sun Mar 01 00:00:00 EST 2020
Evidence for acupoint catgut embedding treatment and TRPV1 gene deletion increasing weight control in murine model.
International journal of molecular medicine
Inprasit C,Huang YC,Lin YW
44-684G was used in Western Blotting to show body weight maintenance may be modulated by calcium ion channel TRPV1.
Sun Mar 01 00:00:00 EST 2020
A novel protective role of sacubitril/valsartan in cyclophosphamide induced lung injury in rats: impact of miRNA-150-3p on NF-κB/MAPK signaling trajectories.
Scientific reports
Abdel-Latif GA,Elwahab AHA,Hasan RA,ElMongy NF,Ramzy MM,Louka ML,Schaalan MF
44-684G was used in Western Blotting to conclude that sacubitril/valsartan effectively abrogated the CP induced lung inflammation and fibrosis, providing a potential promising protection that could be linked to their ability to inhibit miR-150-3p via inhibition of NF-κB and MAPK signaling pathways.
Mon Aug 03 00:00:00 EDT 2020
A novel protective role of sacubitril/valsartan in cyclophosphamide induced lung injury in rats: impact of miRNA-150-3p on NF-κB/MAPK signaling trajectories.
Scientific reports
Abdel-Latif GA,Elwahab AHA,Hasan RA,ElMongy NF,Ramzy MM,Louka ML,Schaalan MF
44-684G was used in Western Blotting to conclude that sacubitril/valsartan effectively abrogated the CP induced lung inflammation and fibrosis, providing a potential promising protection that could be linked to their ability to inhibit miR-150-3p via inhibition of NF-κB and MAPK signaling pathways.
Mon Aug 03 00:00:00 EDT 2020
Hypo-phosphorylated CD147 promotes migration and invasion of hepatocellular carcinoma cells and predicts a poor prognosis.
Cellular oncology (Dordrecht)
Jin J,Wang SJ,Cui J,Li L,Li JY,Liu FL,Sun XX,Jiang JL,Cui HY,Chen ZN
44-684G was used in Western Blotting to determine the role of deregulation of CD147 phosphorylation during cancer progression.
Thu Aug 01 00:00:00 EDT 2019
Whole Genome Microarray Analysis of DUSP4-Deletion Reveals A Novel Role for MAP Kinase Phosphatase-2 (MKP-2) in Macrophage Gene Expression and Function.
International journal of molecular sciences
Neamatallah T,Jabbar S,Tate R,Schroeder J,Shweash M,Alexander J,Plevin R
Published figure using Phospho-p38 MAPK (Thr180, Tyr182) polyclonal antibody (Product # 44-684G) in Western Blot
Fri Jul 12 00:00:00 EDT 2019
12-Lipoxygenase Inhibitor Improves Functions of Cytokine-Treated Human Islets and Type 2 Diabetic Islets.
The Journal of clinical endocrinology and metabolism
Ma K,Xiao A,Park SH,Glenn L,Jackson L,Barot T,Weaver JR,Taylor-Fishwick DA,Luci DK,Maloney DJ,Mirmira RG,Imai Y,Nadler JL
44-684G was used in Western Blotting to test the efficacy of ML355, a highly selective, small molecule inhibitor of 12-lipoxygenase, for the preservation of islet function.
Tue Aug 01 00:00:00 EDT 2017
RARβ2-dependent signaling represses neuronal differentiation in mouse ES cells.
Differentiation; research in biological diversity
Kona SL,Shrestha A,Yi X,Joseph S,Barona HM,Martinez-Ceballos E
44-684G was used in Western Blotting to study the role played by specific retinoic acid receptor types on embryonic stem cell differentiation.
Wed Aug 08 00:00:00 EDT 2018
Exosomal miR-141-3p regulates osteoblast activity to promote the osteoblastic metastasis of prostate cancer.
Oncotarget
Ye Y,Li SL,Ma YY,Diao YJ,Yang L,Su MQ,Li Z,Ji Y,Wang J,Lei L,Fan WX,Li LX,Xu Y,Hao XK
44-684G was used in Western Blotting to discover that exosomal miR-141-3p from MDA prostate cancer 2b cells promoted osteoblast activity and regulated the microenvironment of bone metastases.
Tue Nov 07 00:00:00 EST 2017
Cathepsin S attenuates endosomal EGFR signalling: A mechanical rationale for the combination of cathepsin S and EGFR tyrosine kinase inhibitors.
Scientific reports
Huang CC,Lee CC,Lin HH,Chang JY
44-684G was used in western blot to characterize attenuation of endosomal EGFR signaling by cathepsin S as a mechanical rationale for the combination of EGFR tyrosine kinase and cathepsin S inhibitors
Fri Jul 08 00:00:00 EDT 2016
The genomic landscape of diffuse intrinsic pontine glioma and pediatric non-brainstem high-grade glioma.
Nature genetics
Wu G,Diaz AK,Paugh BS,Rankin SL,Ju B,Li Y,Zhu X,Qu C,Chen X,Zhang J,Easton J,Edmonson M,Ma X,Lu C,Nagahawatte P,Hedlund E,Rusch M,Pounds S,Lin T,Onar-Thomas A,Huether R,Kriwacki R,Parker M,Gupta P,Becksfort J,Wei L,Mulder HL,Boggs K,Vadodaria B,Yergeau D,Russell JC,Ochoa K,Fulton RS,Fulton LL,Jones C,Boop FA,Broniscer A,Wetmore C,Gajjar A,Ding L,Mardis ER,Wilson RK,Taylor MR,Downing JR,Ellison DW,Zhang J,Baker SJ
44-684G was used in western blot to identify signaling pathways that contribute to pediatric high-grade glioma
Thu May 01 00:00:00 EDT 2014
MAPK14/p38α-dependent modulation of glucose metabolism affects ROS levels and autophagy during starvation.
Autophagy
Desideri E,Vegliante R,Cardaci S,Nepravishta R,Paci M,Ciriolo MR
Published figure using Phospho-p38 MAPK (Thr180, Tyr182) polyclonal antibody (Product # 44-684G) in Western Blot
Mon Sep 01 00:00:00 EDT 2014
MAPK14/p38α-dependent modulation of glucose metabolism affects ROS levels and autophagy during starvation.
Autophagy
Desideri E,Vegliante R,Cardaci S,Nepravishta R,Paci M,Ciriolo MR
Published figure using Phospho-p38 MAPK (Thr180, Tyr182) polyclonal antibody (Product # 44-684G) in Western Blot
Mon Sep 01 00:00:00 EDT 2014
Expansion of oligodendrocyte progenitor cells following SIRT1 inactivation in the adult brain.
Nature cell biology
Rafalski VA,Ho PP,Brett JO,Ucar D,Dugas JC,Pollina EA,Chow LM,Ibrahim A,Baker SJ,Barres BA,Steinman L,Brunet A
44-684G was used in western blot to elucidate factors that regulate the generation of adult oligodendrocytes.
Sat Jun 01 00:00:00 EDT 2013
Molecular pathway profiling of T lymphocyte signal transduction pathways; Th1 and Th2 genomic fingerprints are defined by TCR and CD28-mediated signaling.
BMC immunology
Smeets RL,Fleuren WW,He X,Vink PM,Wijnands F,Gorecka M,Klop H,Bauerschmidt S,Garritsen A,Koenen HJ,Joosten I,Boots AM,Alkema W
Wed Mar 14 00:00:00 EDT 2012
T-cell receptor ligation induces distinct signaling pathways in naive vs. antigen-experienced T cells.
Proceedings of the National Academy of Sciences of the United States of America
Adachi K,Davis MM
Tue Jan 25 00:00:00 EST 2011
T-cell receptor ligation induces distinct signaling pathways in naive vs. antigen-experienced T cells.
Proceedings of the National Academy of Sciences of the United States of America
Adachi K,Davis MM
Tue Jan 25 00:00:00 EST 2011
Growth-factor receptor-bound protein-2 (Grb2) signaling in B cells controls lymphoid follicle organization and germinal center reaction.
Proceedings of the National Academy of Sciences of the United States of America
Jang IK,Cronshaw DG,Xie LK,Fang G,Zhang J,Oh H,Fu YX,Gu H,Zou Y
Tue May 10 00:00:00 EDT 2011
Differential modulation of TLR3- and TLR4-mediated dendritic cell maturation and function by progesterone.
Journal of immunology (Baltimore, Md. : 1950)
Jones LA,Kreem S,Shweash M,Paul A,Alexander J,Roberts CW
44-684G was used in western blot to study how progesterone and TLR agonists affect dendritic cell function
Fri Oct 15 00:00:00 EDT 2010
TGFbeta1 antagonistic peptides inhibit TGFbeta1-dependent angiogenesis.
Biochemical pharmacology
Serratì S,Margheri F,Pucci M,Cantelmo AR,Cammarota R,Dotor J,Borràs-Cuesta F,Fibbi G,Albini A,Del Rosso M
44-684G was used in western blot to investigate the cancer blocking activity of TGFbeta antagonist peptides
Sun Mar 01 00:00:00 EST 2009
Critical role of c-jun (NH2) terminal kinase in paracetamol- induced acute liver failure.
Gut
Henderson NC,Pollock KJ,Frew J,Mackinnon AC,Flavell RA,Davis RJ,Sethi T,Simpson KJ
Sun Jul 01 00:00:00 EDT 2007
Critical role of c-jun (NH2) terminal kinase in paracetamol- induced acute liver failure.
Gut
Henderson NC,Pollock KJ,Frew J,Mackinnon AC,Flavell RA,Davis RJ,Sethi T,Simpson KJ
Sun Jul 01 00:00:00 EDT 2007
Chemotherapeutic agents up-regulate the cytomegalovirus promoter: implications for bioluminescence imaging of tumor response to therapy.
Cancer research
Svensson RU,Barnes JM,Rokhlin OW,Cohen MB,Henry MD
44-684G was used in western blot to study the promoter-dependent increase in bioluminescence intensity from CMV-driven luciferase
Thu Nov 01 00:00:00 EDT 2007
Molecular mechanisms involved in interleukin-4-induced human neutrophils: expression and regulation of suppressor of cytokine signaling.
Journal of leukocyte biology
Ratthé C,Pelletier M,Chiasson S,Girard D
Tue May 01 00:00:00 EDT 2007
The peroxisome proliferator-activated receptor gamma agonist pioglitazone reduces the development of cartilage lesions in an experimental dog model of osteoarthritis: in vivo protective effects mediated through the inhibition of key signaling and catabolic pathways.
Arthritis and rheumatism
Boileau C,Martel-Pelletier J,Fahmi H,Mineau F,Boily M,Pelletier JP
44-684G was used in immunohistochemistry - paraffin section to assess the effects of pioglitazone treatment on the development of lesions in a canine model of osteoarthritis
Sun Jul 01 00:00:00 EDT 2007
The mitogen-activated protein kinases (MAPK) p38 and JNK are markers of tumor progression in breast carcinoma.
Gynecologic oncology
Davidson B,Konstantinovsky S,Kleinberg L,Nguyen MT,Bassarova A,Kvalheim G,Nesland JM,Reich R
Fri Sep 01 00:00:00 EDT 2006
Protein synthesis persists during necrotic cell death.
The Journal of cell biology
Saelens X,Festjens N,Parthoens E,Vanoverberghe I,Kalai M,van Kuppeveld F,Vandenabeele P
Mon Feb 14 00:00:00 EST 2005
TNF-alpha promotes a stop signal that inhibits neutrophil polarization and migration via a p38 MAPK pathway.
Journal of leukocyte biology
Lokuta MA,Huttenlocher A
Fri Jul 01 00:00:00 EDT 2005
Urokinase-induced smooth muscle cell responses require distinct signaling pathways: a role for the epidermal growth factor receptor.
Journal of vascular surgery
Nicholl SM,Roztocil E,Davies MG
Fri Apr 01 00:00:00 EST 2005
Plasmin induces smooth muscle cell proliferation.
The Journal of surgical research
Nicholl SM,Roztocil E,Galaria II,Davies MG
Fri Jul 01 00:00:00 EDT 2005
Chemokine receptor CCR2 expression by systemic sclerosis fibroblasts: evidence for autocrine regulation of myofibroblast differentiation.
Arthritis and rheumatism
Carulli MT,Ong VH,Ponticos M,Shiwen X,Abraham DJ,Black CM,Denton CP
44-684G was used in western blot to assess the contribution of CCL2/CCR2 signaling to systemic sclerosis
Thu Dec 01 00:00:00 EST 2005
