The GeneScan™ 120 LIZ™ Size Standard is a five dye-labeled size standard that is designed for reproducible sizing of small fragment analysis data.
GeneScan™ 120 LIZ™ Size Standard is designed for sizing DNA fragments in the 15-120 nucleotides range and provides nine single-stranded labeled fragment of: 15, 20, 25, 35, 50, 62, 80, 110 and 120 nucleotides. The sizing curve generated from these short fragments make the GeneScan™ 120 LIZ™ Size Standard ideal for use with the ABI Prism SNaPshot™ Multiplex Kit as well as other short fragment analysis applications. Each of the DNA fragments is labeled with the LIZ™ fluorophore which results in a single peak when run under denaturing conditions. With the 5th dye LIZ™ your marker fragments can be labeled with the dyes FAM™, VIC™, NED™ or PET™.
Since the standard is labeled with the fifth dye, you can genotype a greater number of markers in a given lane, compared to the four-dye system.