These specialty Wide Bore Tips are designed for researchers dealing with macromolecules like genomic DNA and are especially critical when transferring fragile cellular samples such as macrophages, hybridomas and hepatocytes. When these types of samples are forced through the narrow tip orifice of conventional tips, they are subjected to mechanical shearing forces that can cause trauma and fragmentation to the cells being transferred. The result is often a decrease in plating capability and compromised cell viability. Our wide bore blunt end tip orifice eliminates cell shearing and flow resistance, making this tip ideal for very viscous material.