Product References
Effect of Hypertrophic Scar Fibroblast-Derived Exosomes on Keratinocytes of Normal Human Skin.
International journal of molecular sciences
Cui HS,Joo SY,Lee SY,Cho YS,Kim DH,Seo CH
33-3900 was used in Western Blotting to indicate that HTSF-derived exosomes may play a role in the epidermal pathological development of hypertrophic scar.
Fri Mar 24 00:00:00 EDT 2023
Impact of phospholipase C β1 in glioblastoma: a study on the main mechanisms of tumor aggressiveness.
Cellular and molecular life sciences : CMLS
Ratti S,Marvi MV,Mongiorgi S,Obeng EO,Rusciano I,Ramazzotti G,Morandi L,Asioli S,Zoli M,Mazzatenta D,Suh PG,Manzoli L,Cocco L
33-3900 was used in Western Blot to determine the pathological impact of phospholipase C β1 (PLCβ1) in glioblastoma, confirming that PLCβ1 gene expression correlates with glioma's grade.
Fri Mar 18 00:00:00 EDT 2022
A gastruloid model of the interaction between embryonic and extra-embryonic cell types.
Journal of tissue engineering
Bérenger-Currias NM,Mircea M,Adegeest E,van den Berg PR,Feliksik M,Hochane M,Idema T,Tans SJ,Semrau S
33-3900 was used in Immunohistochemistry-immunofluorescence to establish XEGs to explore heterotypic cellular interactions and their developmental consequences in vitro.
Sat Jul 16 00:00:00 EDT 2022
Acquired hydrocephalus is associated with neuroinflammation, progenitor loss, and cellular changes in the subventricular zone and periventricular white matter.
Fluids and barriers of the CNS
Garcia-Bonilla M,Castaneyra-Ruiz L,Zwick S,Talcott M,Otun A,Isaacs AM,Morales DM,Limbrick DD,McAllister JP
33-3900 was used in Immunohistochemistry to characterize the neuropathology in a pig model of acquired hydrocephalus by analyzing the proliferative cells in the subventricular zone, periventricular white matter alterations, and markers of neuroinflammation in the brain parenchyma and cerebrospinal fluid.
Tue Feb 22 00:00:00 EST 2022
The growth and expansion of meningeal lymphatic networks are affected in craniosynostosis.
Development (Cambridge, England)
Ang PS,Matrongolo MJ,Tischfield MA
33-3900 was used in Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot to show that meningeal lymphatic networks are affected in craniosynostosis, suggesting that the clearance of β-amyloid and waste from the central nervous system may be impeded.
Sat Jan 01 00:00:00 EST 2022
Mfsd2b and Spns2 are essential for maintenance of blood vessels during development and in anaphylactic shock.
Cell reports
Le TNU,Nguyen TQ,Kalailingam P,Nguyen YTK,Sukumar VK,Tan CKH,Tukijan F,Couty L,Hasan Z,Del Gaudio I,Wenk MR,Cazenave-Gassiot A,Camerer E,Nguyen LN
33-3900 was used in Immunohistochemistry to show that S1P export from Mfsd2b and Spns2 is essential for developing and mature vasculature.
Tue Aug 16 00:00:00 EDT 2022
Antagonizing STK25 Signaling Suppresses the Development of Hepatocellular Carcinoma Through Targeting Metabolic, Inflammatory, and Pro-Oncogenic Pathways.
Cellular and molecular gastroenterology and hepatology
Kurhe Y,Caputo M,Cansby E,Xia Y,Kumari S,Anand SK,Howell BW,Marschall HU,Mahlapuu M
33-3900 was used in Immunocytochemistry-immunoflourescence to show that antagonizing STK25 signaling hinders the development of NASH-related HCC and provides an impetus for further analysis of STK25 as a therapeutic target for NASH-induced HCC treatment in human beings.
Mon Apr 04 00:00:00 EDT 2022
Pluripotency state regulates cytoneme selectivity and self-organization of embryonic stem cells.
The Journal of cell biology
Junyent S,Reeves J,Gentleman E,Habib SJ
33-3900 was used in Immunocytochemistry to show that ESC transition to an early primed ESC (pESC) state reduces their pairing with TSCs and impairs synthetic embryogenesis.
Mon Apr 05 00:00:00 EDT 2021
Deficiency of C-X-C chemokine receptor type 5 (CXCR5) gene causes dysfunction of retinal pigment epithelium cells.
Laboratory investigation; a journal of technical methods and pathology
Lennikov A,Mukwaya A,Saddala MS,Huang H
33-3900 was used in Immunohistochemistry to suggest that CXCR5 maintains PI3K/AKT signalling, regulating the expression of genes involved in retinal pigment epithelium epithelial-mesenchymal transition and deregulation.
Mon Feb 01 00:00:00 EST 2021
Drebrin, an actin-binding protein, is required for lens morphogenesis and growth.
Developmental dynamics : an official publication of the American Association of Anatomists
Karnam S,Maddala R,Stiber JA,Rao PV
33-3900 was used in Immunohistochemistry to demonstrate the requirement of drebrin in lens development and growth, with drebrin deficiency leading to impaired lens morphogenesis and microphthalmia.
Mon Nov 01 00:00:00 EDT 2021
Pluripotent stem cell-derived corneal endothelial cells as an alternative to donor corneal endothelium in keratoplasty.
Stem cell reports
Ali M,Khan SY,Gottsch JD,Hutchinson EK,Khan A,Riazuddin SA
33-3900 was used in Immunohistochemistry to evaluate the efficacy of cryopreserved human embryonic stem cell (hESC)-derived corneal endothelial cells (CECs) to form a functional monolayer of corneal endothelium (CE) in rabbits and monkeys.
Tue Sep 14 00:00:00 EDT 2021
Pluripotent stem cell-derived corneal endothelial cells as an alternative to donor corneal endothelium in keratoplasty.
Stem cell reports
Ali M,Khan SY,Gottsch JD,Hutchinson EK,Khan A,Riazuddin SA
33-3900 was used in Immunohistochemistry to evaluate the efficacy of cryopreserved human embryonic stem cell (hESC)-derived corneal endothelial cells (CECs) to form a functional monolayer of corneal endothelium (CE) in rabbits and monkeys.
Tue Sep 14 00:00:00 EDT 2021
Impact of Epithelial-Mesenchymal Immunophenotype on Local Aggressiveness in Papillary Thyroid Carcinoma Invading the Airway.
Journal of clinical medicine
Mandarano M,Andolfi M,Colella R,Monacelli M,Polistena A,Moretti S,Bellezza G,Puxeddu E,Sanguinetti A,Sidoni A,Avenia N,Puma F,Vannucci J
33-3900 was used in Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot to evaluate the prognostic role of E-cadherin, N-cadherin, Aryl hydrocarbon receptor (AhR), and CD147 in different biological behaviours.
Fri Sep 24 00:00:00 EDT 2021
P68 RNA Helicase facilitates Breast Cancer progression by promoting Proliferation and Migration via PDGFR-β/AR axis.
Journal of Cancer
Panchbhai N,Turaga RC,Sharma M,Satyanarayana G,Liu ZR
33-3900 was used in Western Blotting to show that p68 promotes breast cancer cell EMT and cell migration by upregulation of PDGF receptor β (PDGFR-β).
Fri Oct 22 00:00:00 EDT 2021
The novel ZEB1-upregulated protein PRTG induced by Helicobacter pylori infection promotes gastric carcinogenesis through the cGMP/PKG signaling pathway.
Cell death & disease
Xiang T,Yuan C,Guo X,Wang H,Cai Q,Xiang Y,Luo W,Liu G
33-3900 was used in Western Blotting to identify Protogenin (PRTG) was upregulated in both gastric cancer tissues and H. pylori-infected tissues by analyzing dysregulated genes in TCGA and GEO databases.
Thu Feb 04 00:00:00 EST 2021
ZO-1 Regulates Intercalated Disc Composition and Atrioventricular Node Conduction.
Circulation research
Dai W,Nadadur RD,Brennan JA,Smith HL,Shen KM,Gadek M,Laforest B,Wang M,Gemel J,Li Y,Zhang J,Ziman BD,Yan J,Ai X,Beyer EC,Lakata EG,Kasthuri N,Efimov IR,Broman MT,Moskowitz IP,Shen L,Weber CR
33-3900 was used in Immunohistochemistry to determine the role of ZO-1 in cardiac function.
Fri Jul 03 00:00:00 EDT 2020
Prevention of connexin-43 remodeling protects against Duchenne muscular dystrophy cardiomyopathy.
The Journal of clinical investigation
Himelman E,Lillo MA,Nouet J,Gonzalez JP,Zhao Q,Xie LH,Li H,Liu T,Wehrens XH,Lampe PD,Fishman GI,Shirokova N,Contreras JE,Fraidenraich D
33-3900 was used in Western Blotting to study connexin-43 in cardiomyocyte remodeling in a mouse model of Duchenne muscular dystrophy.
Wed Apr 01 00:00:00 EDT 2020
Inhibition of Sema4D/PlexinB1 signaling alleviates vascular dysfunction in diabetic retinopathy.
EMBO molecular medicine
Wu JH,Li YN,Chen AQ,Hong CD,Zhang CL,Wang HL,Zhou YF,Li PC,Wang Y,Mao L,Xia YP,He QW,Jin HJ,Yue ZY,Hu B
33-3900 was used in Western Blot to provide evidence for an alternative therapeutic strategy with anti-Sema4D to complement or improve the current treatment of DR.
Fri Feb 07 00:00:00 EST 2020
Metabolic switch and epithelial-mesenchymal transition cooperate to regulate pluripotency.
The EMBO journal
Sun H,Yang X,Liang L,Zhang M,Li Y,Chen J,Wang F,Yang T,Meng F,Lai X,Li C,He J,He M,Xu Q,Li Q,Lin L,Pei D,Zheng H
33-3900 was used in Immunocytochemistry to investigate the connection between metabolic switch and epithelial-mesenchymal transition in promoting cellular reprogramming.
Wed Apr 15 00:00:00 EDT 2020
R-spondin2 signaling is required for oocyte-driven intercellular communication and follicular growth.
Cell death and differentiation
De Cian MC,Gregoire EP,Le Rolle M,Lachambre S,Mondin M,Bell S,Guigon CJ,Chassot AA,Chaboissier MC
33-3900 was used in Immunohistochemistry (Paraffin) to find that RSPO2/Rspo2 expression is restricted to the oocyte of developing follicles in both human and mouse ovaries from the beginning of the follicular growth.
Thu Oct 01 00:00:00 EDT 2020
FGF18-FGFR2 signaling triggers the activation of c-Jun-YAP1 axis to promote carcinogenesis in a subgroup of gastric cancer patients and indicates translational potential.
Oncogene
Zhang J,Wong CC,Leung KT,Wu F,Zhou Y,Tong JHM,Chan RCK,Li H,Wang Y,Yan H,Liu L,Wu WKK,Chan MWY,Cheng ASL,Yu J,Wong N,Lo KW,To KF,Kang W
33-3900 was used in Western Blotting to highlight the translational potential of FGFR2-c-Jun-YAP1 axis, which may serve as a prognostic biomarker and therapeutic target for GC.
Thu Oct 01 00:00:00 EDT 2020
FDPS promotes glioma growth and macrophage recruitment by regulating CCL20 via Wnt/β-catenin signalling pathway.
Journal of cellular and molecular medicine
Chen Z,Chen G,Zhao H
33-3900 was used in Western Blotting to show that enhancement in FDPS level is observed in glioma tissues and associate with poor prognosis, contributed to tumour growth.
Sat Aug 01 00:00:00 EDT 2020
Promoting roles of long non-coding RNA FAM83H-AS1 in bladder cancer growth, metastasis, and angiogenesis through the c-Myc-mediated ULK3 upregulation.
Cell cycle (Georgetown, Tex.)
Liu B,Gao W,Sun W,Li L,Wang C,Yang X,Liu J,Guo Y
33-3900 was used in Immunohistochemistry (Paraffin), Western Blot to demonstrate that FAM83H-AS1 upregulates ULK3 expression through the transcription factor c-Myc and promotes the progression of BCa.
Tue Dec 01 00:00:00 EST 2020
Promoting roles of long non-coding RNA FAM83H-AS1 in bladder cancer growth, metastasis, and angiogenesis through the c-Myc-mediated ULK3 upregulation.
Cell cycle (Georgetown, Tex.)
Liu B,Gao W,Sun W,Li L,Wang C,Yang X,Liu J,Guo Y
33-3900 was used in Immunohistochemistry (Paraffin), Western Blot to demonstrate that FAM83H-AS1 upregulates ULK3 expression through the transcription factor c-Myc and promotes the progression of BCa.
Tue Dec 01 00:00:00 EST 2020
LncRNA ANCR promotes hepatocellular carcinoma metastasis through upregulating HNRNPA1 expression.
RNA biology
Wen Z,Lian L,Ding H,Hu Y,Xiao Z,Xiong K,Yang Q
33-3900 was used in Western Blotting to show how ANCR promoted HCC metastasis by upregulating HNRNPA1, inhibiting HNRNPA1 degradation and sponging miR-140-3p.
Sun Mar 01 00:00:00 EST 2020
TGF-β1 relieves epithelial-mesenchymal transition reduction in hypospadias induced by DEHP in rats.
Pediatric research
Zhou Y,Huang F,Liu Y,Li D,Zhou Y,Shen L,Long C,Liu X,Wei G
33-3900 was used in Immunohistochemistry (Paraffin) to reveal the preventative effect of TGF-β1 in hypospadias induced by DEHP via the reduction of EMT.
Sun Mar 01 00:00:00 EST 2020
Disabled Homolog 2 (DAB2) Protein in Tumor Microenvironment Correlates with Aggressive Phenotype in Human Urothelial Carcinoma of the Bladder.
Diagnostics (Basel, Switzerland)
Itami Y,Miyake M,Ohnishi S,Tatsumi Y,Gotoh D,Hori S,Morizawa Y,Iida K,Ohnishi K,Nakai Y,Inoue T,Anai S,Tanaka N,Fujii T,Shimada K,Furuya H,Khadka VS,Deng Y,Fujimoto K
33-3900 was used in Western Blotting to investigate the clinical role and biological function of Disabled homolog-2 (DAB2) in human urothelial carcinoma of the bladder (UCB).
Mon Jan 20 00:00:00 EST 2020
Metavinculin modulates force transduction in cell adhesion sites.
Nature communications
Kanoldt V,Kluger C,Barz C,Schweizer AL,Ramanujam D,Windgasse L,Engelhardt S,Chrostek-Grashoff A,Grashoff C
33-3900 was used in Western Blotting to reveal that metavinculin bears higher molecular forces but is less frequently engaged as compared to vinculin, leading to altered force propagation in cell adhesions.
Thu Dec 17 00:00:00 EST 2020
Extracellular vesicles from mast cells induce mesenchymal transition in airway epithelial cells.
Respiratory research
Yin Y,Shelke GV,Lässer C,Brismar H,Lötvall J
33-3900 was used in Western Blotting to find that transforming growth factor beta-1, a well-known EMT inducer, is associated with EVs and mediates the EMT cascade induced in the A549 cells.
Fri May 01 00:00:00 EDT 2020
Connexin-43 reduction prevents muscle defects in a mouse model of manifesting Duchenne muscular dystrophy female carriers.
Scientific reports
Nouet J,Himelman E,Lahey KC,Zhao Q,Fraidenraich D
33-3900 was used in Immunohistochemistry (Frozen) to suggest that Cx43 reduction in symptomatic DMD carrier mice leads to prevention of Cx43 remodeling in the heart and prevention of aberrant Cx43 hemichannel activity in the skeletal muscle macrophages neighboring Cx43 non-expressing fibers.
Mon Mar 30 00:00:00 EDT 2020
Transcriptional downregulation of MHC class I and melanoma de- differentiation in resistance to PD-1 inhibition.
Nature communications
Lee JH,Shklovskaya E,Lim SY,Carlino MS,Menzies AM,Stewart A,Pedersen B,Irvine M,Alavi S,Yang JYH,Strbenac D,Saw RPM,Thompson JF,Wilmott JS,Scolyer RA,Long GV,Kefford RF,Rizos H
33-3900 was used in Western Blotting to demonstrate that TGFß drives the treatment resistant phenotype (MITFlow/AXLhigh) and contributes to MHC class I downregulation in melanoma.
Mon Apr 20 00:00:00 EDT 2020
Differential expression of cell-cell junction proteins in the testis, epididymis, and ductus deferens of domestic turkeys (Meleagris gallopavo) with white and yellow semen.
Poultry science
Pardyak L,Kaminska A,Brzoskwinia M,Hejmej A,Kotula-Balak M,Jankowski J,Ciereszko A,Bilinska B
33-3900 was used in Immunohistochemistry (Paraffin) to provide new information on the localization and expression of cell-cell junction proteins in the testis, epididymis, and ductus deferens of domestic turkeys, and compare expression of junctional protein genes between 2 turkey population, one that produces white normal semen (WNS) and the other that produces yellow abnormal semen.
Wed Jan 01 00:00:00 EST 2020
Ankyrin-B dysfunction predisposes to arrhythmogenic cardiomyopathy and is amenable to therapy.
The Journal of clinical investigation
Roberts JD,Murphy NP,Hamilton RM,Lubbers ER,James CA,Kline CF,Gollob MH,Krahn AD,Sturm AC,Musa H,El-Refaey M,Koenig S,Aneq MÅ,Hoorntje ET,Graw SL,Davies RW,Rafiq MA,Koopmann TT,Aafaqi S,Fatah M,Chiasson DA,Taylor MR,Simmons SL,Han M,van Opbergen CJ,Wold LE,Sinagra G,Mittal K,Tichnell C,Murray B,Codima A,Nazer B,Nguyen DT,Marcus FI,Sobriera N,Lodder EM,van den Berg MP,Spears DA,Robinson JF,Ursell PC,Green AK,Skanes AC,Tang AS,Gardner MJ,Hegele RA,van Veen TA,Wilde AA,Healey JS,Janssen PM,Mestroni L,van Tintelen JP,Calkins H,Judge DP,Hund TJ,Scheinman MM,Mohler PJ
33-3900 was used in Immunohistochemistry-immunofluorescence to evidence for targeted activation of the WNT/Β-catenin pathway as a potential treatment for this disease.
Tue Jul 02 00:00:00 EDT 2019
Ankyrin-B dysfunction predisposes to arrhythmogenic cardiomyopathy and is amenable to therapy.
The Journal of clinical investigation
Roberts JD,Murphy NP,Hamilton RM,Lubbers ER,James CA,Kline CF,Gollob MH,Krahn AD,Sturm AC,Musa H,El-Refaey M,Koenig S,Aneq MÅ,Hoorntje ET,Graw SL,Davies RW,Rafiq MA,Koopmann TT,Aafaqi S,Fatah M,Chiasson DA,Taylor MR,Simmons SL,Han M,van Opbergen CJ,Wold LE,Sinagra G,Mittal K,Tichnell C,Murray B,Codima A,Nazer B,Nguyen DT,Marcus FI,Sobriera N,Lodder EM,van den Berg MP,Spears DA,Robinson JF,Ursell PC,Green AK,Skanes AC,Tang AS,Gardner MJ,Hegele RA,van Veen TA,Wilde AA,Healey JS,Janssen PM,Mestroni L,van Tintelen JP,Calkins H,Judge DP,Hund TJ,Scheinman MM,Mohler PJ
33-3900 was used in Immunohistochemistry-immunofluorescence to evidence for targeted activation of the WNT/Β-catenin pathway as a potential treatment for this disease.
Tue Jul 02 00:00:00 EDT 2019
Elevated endothelial Sox2 causes lumen disruption and cerebral arteriovenous malformations.
The Journal of clinical investigation
Yao J,Wu X,Zhang D,Wang L,Zhang L,Reynolds EX,Hernandez C,Boström KI,Yao Y
33-3900 was used in Western Blotting to show that endothelial-mesenchymal transitions emerged in endothelial cells of cerebral arteriovenous malformation and caused disruption of the lumen.
Mon Jun 24 00:00:00 EDT 2019
Elevated endothelial Sox2 causes lumen disruption and cerebral arteriovenous malformations.
The Journal of clinical investigation
Yao J,Wu X,Zhang D,Wang L,Zhang L,Reynolds EX,Hernandez C,Boström KI,Yao Y
33-3900 was used in Western Blotting to show that endothelial-mesenchymal transitions emerged in endothelial cells of cerebral arteriovenous malformation and caused disruption of the lumen.
Mon Jun 24 00:00:00 EDT 2019
Elevated endothelial Sox2 causes lumen disruption and cerebral arteriovenous malformations.
The Journal of clinical investigation
Yao J,Wu X,Zhang D,Wang L,Zhang L,Reynolds EX,Hernandez C,Boström KI,Yao Y
33-3900 was used in Western Blotting to show that endothelial-mesenchymal transitions emerged in endothelial cells of cerebral arteriovenous malformation and caused disruption of the lumen.
Mon Jun 24 00:00:00 EDT 2019
FGF18, a prominent player in FGF signaling, promotes gastric tumorigenesis through autocrine manner and is negatively regulated by miR-590-5p.
Oncogene
Zhang J,Zhou Y,Huang T,Wu F,Pan Y,Dong Y,Wang Y,Chan AKY,Liu L,Kwan JSH,Cheung AHK,Wong CC,Lo AKF,Cheng ASL,Yu J,Lo KW,Kang W,To KF
33-3900 was used in Western Blotting to investigate the expression and functional role of fibroblast growth factor 18 in gastric cancer and elucidate its regulatory mechanisms.
Tue Jan 01 00:00:00 EST 2019
mTORC1/rpS6 signaling complex modifies BTB transport function: an in vivo study using the adjudin model.
American journal of physiology. Endocrinology and metabolism
Yan M,Li L,Mao B,Li H,Li SYT,Mruk D,Silvestrini B,Lian Q,Ge R,Cheng CY
33-3900 was used in Immunohistochemistry (Paraffin) to demonstrate that combining overexpression of p-rpS6-MT with a male contraceptive (e.g., adjudin) potentiate the drug bioavailability by modifying the blood-testis barrier.
Mon Jul 01 00:00:00 EDT 2019
The N-cadherin interactome in primary cardiomyocytes as defined using quantitative proximity proteomics.
Journal of cell science
Li Y,Merkel CD,Zeng X,Heier JA,Cantrell PS,Sun M,Stolz DB,Watkins SC,Yates NA,Kwiatkowski AV
33-3900 was used in Immunocytochemistry-immunoflourescence to define the architecture, dynamics and proteome of the cardiomyocyte adherens junctions.
Mon Feb 11 00:00:00 EST 2019
Ankyrin-G regulated epithelial phenotype is required for mouse lens morphogenesis and growth.
Developmental biology
Rasiah PK,Maddala R,Bennett V,Rao PV
33-3900 was used in Immunohistochemistry-immunofluorescence to study the function of scaffolding protein ankyrin-G (AnkG) in lens development of mice.
Fri Feb 01 00:00:00 EST 2019
Secreted protein acidic and rich in cysteine (SPARC) induces epithelial-mesenchymal transition, enhancing migration and invasion, and is associated with high Gleason score in prostate cancer.
Asian journal of andrology
López-Moncada F,Torres MJ,Castellón EA,Contreras HR
33-3900 was used in Western Blotting to show that secreted protein acidic and rich in cysteine (SPARC) is highly expressed in PCa tissues with a higher Gleason score.
Mon Aug 17 00:00:00 EDT 2020
New Insights into the Role of Polybromo-1 in Prostate Cancer.
International journal of molecular sciences
Mota STS,Vecchi L,Zóia MAP,Oliveira FM,Alves DA,Dornelas BC,Bezerra SM,Andrade VP,Maia YCP,Neves AF,Goulart LR,Araújo TG
33-3900 was used in Flow cytometry/Cell sorting to study the role of Polybromo-1 in prostate cancer.
Wed Jun 12 00:00:00 EDT 2019
Visco-Node-Pore Sensing: A Microfluidic Rheology Platform to Characterize Viscoelastic Properties of Epithelial Cells.
iScience
Kim J,Li B,Scheideler OJ,Kim Y,Sohn LL
33-3900 was used in Immunocytochemistry-immunoflourescence to show Visco-NPS identifies viscoelastic characteristics of cell populations, providing a biophysical understanding of cellular behavior and a potential for clinical applications.
Fri Mar 29 00:00:00 EDT 2019
YBX-1 mediated sorting of miR-133 into hypoxia/reoxygenation-induced EPC-derived exosomes to increase fibroblast angiogenesis and MEndoT.
Stem cell research & therapy
Lin F,Zeng Z,Song Y,Li L,Wu Z,Zhang X,Li Z,Ke X,Hu X
33-3900 was used in Western Blotting to show that H/R treatment promoted miR-133 expression in EPCs and EPC-derived exosomes.
Fri Aug 23 00:00:00 EDT 2019
Pannexin1 Is Associated with Enhanced Epithelial-To-Mesenchymal Transition in Human Patient Breast Cancer Tissues and in Breast Cancer Cell Lines.
Cancers
Jalaleddine N,El-Hajjar L,Dakik H,Shaito A,Saliba J,Safi R,Zibara K,El-Sabban M
33-3900 was used in Immunocytochemistry to suggest that pannexin1 overexpression in breast cancer is associated with a shift towards an epithelial-to-mesenchymal transition phenotype that initiates a tumour-promoting effect.
Sat Dec 07 00:00:00 EST 2019
Cdc42 is involved in NC1 peptide-regulated BTB dynamics through actin and microtubule cytoskeletal reorganization.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Su W,Cheng CY
33-3900 was used in Immunocytochemistry to show that this NC1 peptide regulates testis function by inducing Sertoli cell blood-testis barrier (BTB) remodeling and is also capable of inducing elongate spermatid exfoliation through its disruptive effects on the organization of actin- and microtubule (MT)-based cytoskeletons at these cell adhesion sites.
Sun Dec 01 00:00:00 EST 2019
Planar cell polarity protein Dishevelled 3 (Dvl3) regulates ectoplasmic specialization (ES) dynamics in the testis through changes in cytoskeletal organization.
Cell death & disease
Li L,Mao B,Yan M,Wu S,Ge R,Lian Q,Cheng CY
33-3900 was used in Immunohistochemistry-immunofluorescence to study the role of Dishevelled 3 in supporting Sertoli cell tight junction-permeability barrier function.
Tue Feb 26 00:00:00 EST 2019
Defining new mechanistic roles for αII spectrin in cardiac function.
The Journal of biological chemistry
Lubbers ER,Murphy NP,Musa H,Huang CY,Gupta R,Price MV,Han M,Daoud E,Gratz D,El Refaey M,Xu X,Hoeflinger NK,Friel EL,Lancione P,Wallace MJ,Cavus O,Simmons SL,Williams JL,Skaf M,Koenig SN,Janssen PML,Rasband MN,Hund TJ,Mohler PJ
33-3900 was used in Immunohistochemistry-immunofluorescence to study the mechanistic role of aII spectrin in the vertebrate heart.
Fri Jun 14 00:00:00 EDT 2019
Dynein 1 supports spermatid transport and spermiation during spermatogenesis in the rat testis.
American journal of physiology. Endocrinology and metabolism
Wen Q,Tang EI,Lui WY,Lee WM,Wong CKC,Silvestrini B,Cheng CY
33-3900 was used in Immunohistochemistry to investigate the role of dynein 1 in supporting the transport of spermatids and organelles across the seminiferous epithelium during spermatogenesis.
Thu Nov 01 00:00:00 EDT 2018
Differential Wnt-mediated programming and arrhythmogenesis in right versus left ventricles.
Journal of molecular and cellular cardiology
Li G,Khandekar A,Yin T,Hicks SC,Guo Q,Takahashi K,Lipovsky CE,Brumback BD,Rao PK,Weinheimer CJ,Rentschler SL
33-3900 was used in Immunohistochemistry (Paraffin) to propose that embryonic perturbation of Wnt signalling in cardiomyocytes leads to right ventricular arrhythmic susceptibility in the adult heart through chamber-specific regulation of genes regulating cellular electrophysiology.
Mon Oct 01 00:00:00 EDT 2018
Intercalated cushion cells within the cardiac outflow tract are derived from the myocardial troponin T type 2 (Tnnt2) Cre lineage.
Developmental dynamics : an official publication of the American Association of Anatomists
Mifflin JJ,Dupuis LE,Alcala NE,Russell LG,Kern CB
33-3900 was used in Immunohistochemistry to generate three-dimensional lineage mapping of AV and PV cusps during intercalated cushion development.
Wed Aug 01 00:00:00 EDT 2018
Actin nucleator Spire 1 is a regulator of ectoplasmic specialization in the testis.
Cell death & disease
Wen Q,Li N,Xiao X,Lui WY,Chu DS,Wong CKC,Lian Q,Ge R,Lee WM,Silvestrini B,Cheng CY
33-3900 was used in Immunohistochemistry to demonstrate that Spire 1 is an ectoplasmic specialization regulator to support germ cell development during spermatogenesis.
Mon Feb 12 00:00:00 EST 2018
Nitric oxide-sensitive guanylyl cyclase stimulation improves experimental heart failure with preserved ejection fraction.
JCI insight
Wilck N,Markó L,Balogh A,Kräker K,Herse F,Bartolomaeus H,Szijártó IA,Gollasch M,Reichhart N,Strauss O,Heuser A,Brockschnieder D,Kretschmer A,Lesche R,Sohler F,Stasch JP,Sandner P,Luft FC,Müller DN,Dechend R,Haase N
33-3900 was used in Immunohistochemistry to demonstrate that nitric oxide-sensitive soluble guanylyl cyclase stimulation is effective in improving several heart failure with preserved ejection fraction facets.
Thu Feb 22 00:00:00 EST 2018
Activation of hepatocyte growth factor/MET signaling initiates oncogenic transformation and enhances tumor aggressiveness in the murine prostate.
The Journal of biological chemistry
Mi J,Hooker E,Balog S,Zeng H,Johnson DT,He Y,Yu EJ,Wu H,Le V,Lee DH,Aldahl J,Gonzalgo ML,Sun Z
33-3900 was used in Immunohistochemistry to indicate a role for MET in hastening tumorigenesis and metastasis when combined with the loss of tumor suppressors.
Fri Dec 28 00:00:00 EST 2018
Inhibition of soluble epoxide hydrolase prevents diabetic retinopathy.
Nature
Hu J,Dziumbla S,Lin J,Bibli SI,Zukunft S,de Mos J,Awwad K,Frömel T,Jungmann A,Devraj K,Cheng Z,Wang L,Fauser S,Eberhart CG,Sodhi A,Hammock BD,Liebner S,Müller OJ,Glaubitz C,Hammes HP,Popp R,Fleming I
33-3900 was used in Immunohistochemistry-wholemount to identify soluble epoxide hydrolase as a key enzyme that initiates pericyte loss and breakdown of endothelial barrier function.
Thu Dec 14 00:00:00 EST 2017
Neurons secrete miR-132-containing exosomes to regulate brain vascular integrity.
Cell research
Xu B,Zhang Y,Du XF,Li J,Zi HX,Bu JW,Yan Y,Han H,Du JL
33-3900 was used in Western Blotting to indicate that miR-132 acts as an intercellular signal mediating neural regulation of the brain vascular integrity.
Sat Jul 01 00:00:00 EDT 2017
Neurons secrete miR-132-containing exosomes to regulate brain vascular integrity.
Cell research
Xu B,Zhang Y,Du XF,Li J,Zi HX,Bu JW,Yan Y,Han H,Du JL
33-3900 was used in Western Blotting to indicate that miR-132 acts as an intercellular signal mediating neural regulation of the brain vascular integrity.
Sat Jul 01 00:00:00 EDT 2017
Mosaic Analysis with Double Markers Reveals Distinct Sequential Functions of Lgl1 in Neural Stem Cells.
Neuron
Beattie R,Postiglione MP,Burnett LE,Laukoter S,Streicher C,Pauler FM,Xiao G,Klezovitch O,Vasioukhin V,Ghashghaei TH,Hippenmeyer S
33-3900 was used in Immunohistochemistry to suggest that NSC-mediated neuron and glia production is regulated through the interplay of sequential Lgl1-dependent global and cell intrinsic mechanisms.
Wed May 03 00:00:00 EDT 2017
A Critical Role of Presynaptic Cadherin/Catenin/p140Cap Complexes in Stabilizing Spines and Functional Synapses in the Neocortex.
Neuron
Li MY,Miao WY,Wu QZ,He SJ,Yan G,Yang Y,Liu JJ,Taketo MM,Yu X
33-3900 was used in Western Blot to demonstrate a critical role of presynaptic cadherin/catenin cell adhesion complexes in stabilising functional synapses and spines in the developing neocortex.
Wed Jun 21 00:00:00 EDT 2017
Amplification of R-spondin1 signaling induces granulosa cell fate defects and cancers in mouse adult ovary.
Oncogene
De Cian MC,Pauper E,Bandiera R,Vidal VP,Sacco S,Gregoire EP,Chassot AA,Panzolini C,Wilhelm D,Pailhoux E,Youssef SA,de Bruin A,Teerds K,Schedl A,Gillot I,Chaboissier MC
33-3900 was used in immunohistochemistry - frozen section to study induction of granulosa cell fate and defects and cancers in mouse adult ovary by amplification of R-spondin1 signaling
Thu Jan 12 00:00:00 EST 2017
MicroRNA-661 modulates redox and metabolic homeostasis in colon cancer.
Molecular oncology
Gómez de Cedrón M,Acín Pérez R,Sánchez-Martínez R,Molina S,Herranz J,Feliu J,Reglero G,Enríquez JA,Ramírez de Molina A
33-3900 was used in Western Blotting to describe the role of microRNA-661 as an epigenetic regulator of colon cancer cell metabolism.
Fri Dec 01 00:00:00 EST 2017
Identification of a Novel Human E-Cadherin Splice Variant and Assessment of Its Effects Upon EMT-Related Events.
Journal of cellular physiology
Matos ML,Lapyckyj L,Rosso M,Besso MJ,Mencucci MV,Briggiler CI,Giustina S,Furlong LI,Vazquez-Levin MH
333900 was used in immunocytochemistry and western blot to investigate the alternative splicing of E-cadherin mRNA
Thu Jun 01 00:00:00 EDT 2017
Regulation of the blood-testis barrier by a local axis in the testis: role of laminin α2 in the basement membrane.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Gao Y,Mruk D,Chen H,Lui WY,Lee WM,Cheng CY
333900 was used in immunocytochemistry and western blot to explore how laminin2 in the basement membrane modulates the blood testis barrier dynamics during spermatogenesis
Wed Feb 01 00:00:00 EST 2017
Regulation of spermatogenesis by a local functional axis in the testis: role of the basement membrane-derived noncollagenous 1 domain peptide.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Chen H,Mruk DD,Lee WM,Cheng CY
33-3900 was used in Immunocytochemistry to report that NC1 domain derived from collagen α3(IV) chain-a major structural component of the BM-was capable of inducing BTB remodeling.
Tue Aug 01 00:00:00 EDT 2017
Regulation of spermatogenesis by a local functional axis in the testis: role of the basement membrane-derived noncollagenous 1 domain peptide.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Chen H,Mruk DD,Lee WM,Cheng CY
33-3900 was used in Immunocytochemistry to report that NC1 domain derived from collagen α3(IV) chain-a major structural component of the BM-was capable of inducing BTB remodeling.
Tue Aug 01 00:00:00 EDT 2017
Regulation of spermatogenesis by a local functional axis in the testis: role of the basement membrane-derived noncollagenous 1 domain peptide.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Chen H,Mruk DD,Lee WM,Cheng CY
33-3900 was used in Immunocytochemistry to report that NC1 domain derived from collagen α3(IV) chain-a major structural component of the BM-was capable of inducing BTB remodeling.
Tue Aug 01 00:00:00 EDT 2017
TGF-β1 affects cell-cell adhesion in the heart in an NCAM1-dependent mechanism.
Journal of molecular and cellular cardiology
Ackermann MA,Petrosino JM,Manring HR,Wright P,Shettigar V,Kilic A,Janssen PML,Ziolo MT,Accornero F
33-3900 was used in Western Blotting to investigate the molecular function of Transforming Growth Factor beta 1 in controlling cell-cell adhesion in the heart.
Wed Nov 01 00:00:00 EDT 2017
Mild hypothermia preserves myocardial conduction during ischemia by maintaining gap junction intracellular communication and Na+ channel function.
American journal of physiology. Heart and circulatory physiology
Nassal MMJ,Wan X,Dale Z,Deschênes I,Wilson LD,Piktel JS
33-3900 was used in Western Blotting to study the effect of hypothermia on gap junction coupling and Na+ channel function in acute cardiac ischemia.
Mon May 01 00:00:00 EDT 2017
Mild hypothermia preserves myocardial conduction during ischemia by maintaining gap junction intracellular communication and Na+ channel function.
American journal of physiology. Heart and circulatory physiology
Nassal MMJ,Wan X,Dale Z,Deschênes I,Wilson LD,Piktel JS
33-3900 was used in Western Blotting to study the effect of hypothermia on gap junction coupling and Na+ channel function in acute cardiac ischemia.
Mon May 01 00:00:00 EDT 2017
Decreased WNT/β-catenin signalling contributes to the pathogenesis of dilated cardiomyopathy caused by mutations in the lamin a/C gene.
Human molecular genetics
Le Dour C,Macquart C,Sera F,Homma S,Bonne G,Morrow JP,Worman HJ,Muchir A
333900 was used in immunocytochemistry to show that decreased WNT/beta-catenin contributes to the pathophysiology of lamin A/C gene cardiomyopathy
Sun Jan 15 00:00:00 EST 2017
Basement Membrane Laminin α2 Regulation of BTB Dynamics via Its Effects on F-Actin and Microtubule Cytoskeletons Is Mediated Through mTORC1 Signaling.
Endocrinology
Gao Y,Chen H,Lui WY,Lee WM,Cheng CY
33-3900 was used in Immunocytochemistry to study the mechanism of laminin α2-mediated regulation in Sertoli cell blood-testes barrier dynamics.
Sat Apr 01 00:00:00 EDT 2017
Basement Membrane Laminin α2 Regulation of BTB Dynamics via Its Effects on F-Actin and Microtubule Cytoskeletons Is Mediated Through mTORC1 Signaling.
Endocrinology
Gao Y,Chen H,Lui WY,Lee WM,Cheng CY
33-3900 was used in Immunocytochemistry to study the mechanism of laminin α2-mediated regulation in Sertoli cell blood-testes barrier dynamics.
Sat Apr 01 00:00:00 EDT 2017
Spontaneous acquisition of infinite proliferative capacity by a rabbit corneal endothelial cell line with maintenance of phenotypic and physiological characteristics.
Journal of tissue engineering and regenerative medicine
Kageyama T,Hayashi R,Hara S,Yoshikawa K,Ishikawa Y,Yamato M,Nishida K
33-3900 was used in immunohistochemistry and western blot to generate and characterize a novel rabbit corneal endothelial cell line.
Sat Apr 01 00:00:00 EDT 2017
Spontaneous acquisition of infinite proliferative capacity by a rabbit corneal endothelial cell line with maintenance of phenotypic and physiological characteristics.
Journal of tissue engineering and regenerative medicine
Kageyama T,Hayashi R,Hara S,Yoshikawa K,Ishikawa Y,Yamato M,Nishida K
33-3900 was used in immunohistochemistry and western blot to generate and characterize a novel rabbit corneal endothelial cell line.
Sat Apr 01 00:00:00 EDT 2017
Proteomic analysis of ovarian cancer cells during epithelial-mesenchymal transition (EMT) induced by epidermal growth factor (EGF) reveals mechanisms of cell cycle control.
Journal of proteomics
Grassi ML,Palma CS,Thomé CH,Lanfredi GP,Poersch A,Faça VM
333900 was used in immunohistochemistry to identify signaling pathways that mediate the EGF-induced epithelial to mesenchymal transition
Mon Jan 16 00:00:00 EST 2017
Perfluorooctanesulfonate (PFOS)-induced Sertoli cell injury through a disruption of F-actin and microtubule organization is mediated by Akt1/2.
Scientific reports
Gao Y,Chen H,Xiao X,Lui WY,Lee WM,Mruk DD,Cheng CY
33-3900 was used in Immunofluorescence-cell culture cells to investigate the effect of PFOS on Setoli cell blood-testis barrier, showing that injury occurs via Akt1/2 and disrupts F-actin and microtubule organization.
Mon Apr 24 00:00:00 EDT 2017
Perfluorooctanesulfonate (PFOS)-induced Sertoli cell injury through a disruption of F-actin and microtubule organization is mediated by Akt1/2.
Scientific reports
Gao Y,Chen H,Xiao X,Lui WY,Lee WM,Mruk DD,Cheng CY
33-3900 was used in Immunofluorescence-cell culture cells to investigate the effect of PFOS on Setoli cell blood-testis barrier, showing that injury occurs via Akt1/2 and disrupts F-actin and microtubule organization.
Mon Apr 24 00:00:00 EDT 2017
Intermittent hypoxia causes NOX2-dependent remodeling of atrial connexins.
BMC cell biology
Gemel J,Su Z,Gileles-Hillel A,Khalyfa A,Gozal D,Beyer EC
33-3900 was used in immunohistochemistry to examine connexin40 and connexin43 expression in mouse models of hypoxia and sleep apnea
Tue Jan 17 00:00:00 EST 2017
Cellular inhibitor of apoptosis protein 2 promotes the epithelial-mesenchymal transition in triple-negative breast cancer cells through activation of the AKT signaling pathway.
Oncotarget
Jo SJ,Park PG,Cha HR,Ahn SG,Kim MJ,Kim H,Koo JS,Jeong J,Park JH,Dong SM,Lee JM
33-3900 was used in Western Blotting to investigate the mechanism by which cIAP2 regulates the epithelial-mesenchymal transition in triple negative breast cancer cells.
Tue Oct 03 00:00:00 EDT 2017
Direct Cardiac Reprogramming as a Novel Therapeutic Strategy for Treatment of Myocardial Infarction.
Methods in molecular biology (Clifton, N.J.)
Ma H,Wang L,Liu J,Qian L
33-3900 was used in Immunohistochemistry to develop a detailed protocol for both in vitro and in vivo induced cardiomyocyte generation.
Mon Jan 15 00:00:00 EST 2018
Electronic Cigarette Smoke Impairs Normal Mesenchymal Stem Cell Differentiation.
Scientific reports
Shaito A,Saliba J,Husari A,El-Harakeh M,Chhouri H,Hashem Y,Shihadeh A,El-Sabban M
33-3900 was used in Western Blotting to examine the effects of chronic inhalation of potential toxicants emitted by ecigarettes, and compare the risks with combustible cigarettes.
Fri Oct 27 00:00:00 EDT 2017
Biased Expression of the FOXP3Δ3 Isoform in Aggressive Bladder Cancer Mediates Differentiation and Cisplatin Chemotherapy Resistance.
Clinical cancer research : an official journal of the American Association for Cancer Research
Zhang H,Prado K,Zhang KX,Peek EM,Lee J,Wang X,Huang J,Li G,Pellegrini M,Chin AI
33-3900 was used in immunohistochemistry - paraffin section to determine mediation of differentiation and cisplatin chemotherapy resistance by biased expression of the FOXP3delta3 isoform in aggressive bladder cancer
Tue Nov 01 00:00:00 EDT 2016
An epithelial to mesenchymal transition programme does not usually drive the phenotype of invasive lobular carcinomas.
The Journal of pathology
McCart Reed AE,Kutasovic JR,Vargas AC,Jayanthan J,Al-Murrani A,Reid LE,Chambers R,Da Silva L,Melville L,Evans E,Porter A,Papadimos D,Thompson EW,Lakhani SR,Simpson PT
333900 was used in immunohistochemistry - paraffin section to study markers of the epithelial to mesenchymal transition using invasive lobular carcinoma samples
Tue Mar 01 00:00:00 EST 2016
The CaSm (LSm1) oncogene promotes transformation, chemoresistance and metastasis of pancreatic cancer cells.
Oncogenesis
Little EC,Camp ER,Wang C,Watson PM,Watson DK,Cole DJ
33-3900 was used in western blot to investigate how CaSm promotes pancreatic cancer
Mon Jan 11 00:00:00 EST 2016
Cell coupling mediated by connexin 26 selectively contributes to reduced adhesivity and increased migration.
Journal of cell science
Polusani SR,Kalmykov EA,Chandrasekhar A,Zucker SN,Nicholson BJ
33-3900 was used in Western Blotting to show that expression of Cx26 in HeLa cells specifically enhances cell motility in scrape wounding and sparse culture models.
Thu Dec 01 00:00:00 EST 2016
Isolation of an ES-Derived Cardiovascular Multipotent Cell Population Based on VE-Cadherin Promoter Activity.
Stem cells international
Maltabe VA,Barka E,Kontonika M,Florou D,Kouvara-Pritsouli M,Roumpi M,Agathopoulos S,Kolettis TM,Kouklis P
333900 was used in immunohistochemistry to describe a cardiovascular progenitor population derived during embryonic stem cell differentiation
Thu Oct 01 00:00:00 EDT 2020
Planar Cell Polarity (PCP) Protein Vangl2 Regulates Ectoplasmic Specialization Dynamics via Its Effects on Actin Microfilaments in the Testes of Male Rats.
Endocrinology
Chen H,Mruk DD,Lee WM,Cheng CY
33-3900 was used in immunocytochemistry, immunoprecipitation, and western blot to determine regulation of ectoplasmic specialization dynamics via its effects on actin microfilaments in the testes of male rats by planar cell polarity (PCP) protein Vangl2
Sun May 01 00:00:00 EDT 2016
Interleukin 1alpha-induced disruption of the Sertoli cell cytoskeleton affects gap junctional communication.
Cellular signalling
Chojnacka K,Bilinska B,Mruk DD
33-3900 was used in immunocytochemistry to characterize disruption of the sertolic cell cytoskeleton by interleukin 1alpha and its affect on gap junctional communication
Sun May 01 00:00:00 EDT 2016
Specific deletion of AMP-activated protein kinase (α1AMPK) in mouse Sertoli cells modifies germ cell quality.
Molecular and cellular endocrinology
Bertoldo MJ,Guibert E,Faure M,Guillou F,Ramé C,Nadal-Desbarats L,Foretz M,Viollet B,Dupont J,Froment P
33-3900 was used in western blot to elucidate a deletion of AMP-activated protein kinase in mouse Sertoli cells that modify germ cell quality
Sat Mar 05 00:00:00 EST 2016
Phosphorylation at Connexin43 Serine-368 Is Necessary for Myocardial Conduction During Metabolic Stress.
Journal of cardiovascular electrophysiology
Nassal MM,Werdich AA,Wan X,Hoshi M,Deschênes I,Rosenbaum DS,Donahue JK
33-3900 was used in western blot to determine the functional effects of S368 phosphorylation of connexin 43.
Fri Jan 01 00:00:00 EST 2016
Polarity protein Crumbs homolog-3 (CRB3) regulates ectoplasmic specialization dynamics through its action on F-actin organization in Sertoli cells.
Scientific reports
Gao Y,Lui WY,Lee WM,Cheng CY
33-3900 was used in immunocytochemistry, immunohistochemistry - frozen section, and western blot report that crumbs homolog 3 is an actin microfilament regulator
Thu Jun 30 00:00:00 EDT 2016
Overexpression of plastin 3 in Sertoli cells disrupts actin microfilament bundle homeostasis and perturbs the tight junction barrier.
Spermatogenesis
Li N,Lee WM,Cheng CY
333900 was used in immunocytochemistry and western blot to examine the organization of actin microfilaments in Sertoli cell at the blood testis barrier
Fri Apr 01 00:00:00 EDT 2016
Two-Pore K+ Channel TREK-1 Regulates Sinoatrial Node Membrane Excitability.
Journal of the American Heart Association
Unudurthi SD,Wu X,Qian L,Amari F,Onal B,Li N,Makara MA,Smith SA,Snyder J,Fedorov VV,Coppola V,Anderson ME,Mohler PJ,Hund TJ
33-3900 was used in Western Blotting to study the role of the mechanosensitive 2-pore K(+) channel family member, TREK-1, in the control of cardiac excitability.
Wed Apr 20 00:00:00 EDT 2016
Serine Protease Activation Essential for Endothelial-Mesenchymal Transition in Vascular Calcification.
Circulation research
Yao J,Guihard PJ,Blazquez-Medela AM,Guo Y,Moon JH,Jumabay M,Boström KI,Yao Y
33-3900 was used in Immunohistochemistry-immunofluorescence to determine the role of specific serine proteases and sex determining region Y-box 2 in the initiation of endothelial-mesenchymal transitions.
Fri Oct 09 00:00:00 EDT 2015
Expression of miR-200c in claudin-low breast cancer alters stem cell functionality, enhances chemosensitivity and reduces metastatic potential.
Oncogene
Knezevic J,Pfefferle AD,Petrovic I,Greene SB,Perou CM,Rosen JM
33-3900 was used in immunohistochemistry - paraffin section and western blot to investigate the effect of miR-200c on claudin-low breast cancer.
Thu Dec 03 00:00:00 EST 2015
Flutamide alters the distribution of c-Src and affects the N-cadherin-β-catenin complex in the seminiferous epithelium of adult rat.
Andrology
Zarzycka M,Chojnacka K,Mruk DD,Gorowska E,Hejmej A,Kotula-Balak M,Pardyak L,Bilinska B
33-3900 was used in immunohistochemistry - paraffin section, immunoprecipitation, and western blot to study the effect of flutamide on the distribution of c-Src and the N-cadherin-beta-catenin complex in the seminiferous epithelium of adult rat
Fri May 01 00:00:00 EDT 2015
Heterogeneity between triple negative breast cancer cells due to differential activation of Wnt and PI3K/AKT pathways.
Experimental cell research
Martínez-Revollar G,Garay E,Martin-Tapia D,Nava P,Huerta M,Lopez-Bayghen E,Meraz-Cruz N,Segovia J,González-Mariscal L
33-3900 was used in western blot to characterize two clones from triple negative breast MDA-MB-231 cancer cells
Sun Nov 15 00:00:00 EST 2015
Characterization of the equine blood-testis barrier during tubular development in normal and cryptorchid stallions.
Theriogenology
Rode K,Sieme H,Richterich P,Brehm R
33-3900 was used in immunohistochemistry - paraffin section and western blot to characterize the equine blood-testis barrier during tubular development in normal and cryptorchid stallions
Tue Sep 15 00:00:00 EDT 2015
Loss of ATM accelerates pancreatic cancer formation and epithelial-mesenchymal transition.
Nature communications
Russell R,Perkhofer L,Liebau S,Lin Q,Lechel A,Feld FM,Hessmann E,Gaedcke J,Güthle M,Zenke M,Hartmann D,von Figura G,Weissinger SE,Rudolph KL,Möller P,Lennerz JK,Seufferlein T,Wagner M,Kleger A
33-3900 was used in immunohistochemistry - paraffin section to characterize a conditional knock out of ataxia telangiectasia-mutated as a mouse model of pancreatic ductal adenocarcinoma
Wed Jul 29 00:00:00 EDT 2015
VEGF-mediated angiogenesis links EMT-induced cancer stemness to tumor initiation.
Cancer research
Fantozzi A,Gruber DC,Pisarsky L,Heck C,Kunita A,Yilmaz M,Meyer-Schaller N,Cornille K,Hopfer U,Bentires-Alj M,Christofori G
33-3900 was used in immunohistochemistry - paraffin section to evaluate the role of VEGF-mediated angiogenesis in EMT-induced cancer stemness and tumorigenesis
Sat Mar 01 00:00:00 EST 2014
rpS6 regulates blood-testis barrier dynamics through Akt-mediated effects on MMP-9.
Journal of cell science
Mok KW,Mruk DD,Cheng CY
Sat Nov 15 00:00:00 EST 2014
14-3-3γ-Mediated transport of plakoglobin to the cell border is required for the initiation of desmosome assembly in vitro and in vivo.
Journal of cell science
Sehgal L,Mukhopadhyay A,Rajan A,Khapare N,Sawant M,Vishal SS,Bhatt K,Ambatipudi S,Antao N,Alam H,Gurjar M,Basu S,Mathur R,Borde L,Hosing AS,Vaidya MM,Thorat R,Samaniego F,Kolthur-Seetharam U,Dalal SN
33-3900 was used in immunohistochemistry to study the contribution of 4-3-3γ to testis organization and spermatogenesis.
Thu May 15 00:00:00 EDT 2014
Perfluorooctanesulfonate (PFOS) perturbs male rat Sertoli cell blood-testis barrier function by affecting F-actin organization via p-FAK-Tyr(407): an in vitro study.
Endocrinology
Wan HT,Mruk DD,Wong CK,Cheng CY
33-3900 was used in Western Blotting to study how PFOS-induced BTB disruption is mediated by down-regulating phosphorylated FAK-Tyr(407) and connexin-43.
Wed Jan 01 00:00:00 EST 2014
HNF4α induced chemosensitivity to oxaliplatin and 5-FU mediated by OCT1 and CNT3 in renal cell carcinoma.
Journal of pharmaceutical sciences
Hagos Y,Wegner W,Kuehne A,Floerl S,Marada VV,Burckhardt G,Henjakovic M
33-3900 was used in Immunofluorescence to show that HNF4α increases the expression of OCT1 and CNT3 in RCCNG1 cells, thereby increasing the chemosensitivity of tumor cells to oxaliplatin and 5-FU.
Wed Oct 01 00:00:00 EDT 2014
Novel three-dimensional in vitro models of ovarian endometriosis.
Journal of ovarian research
Brueggmann D,Templeman C,Starzinski-Powitz A,Rao NP,Gayther SA,Lawrenson K
33-3900 was used in western blot to develop and characterize a novel three-dimensional cell culture model of ovarian endometriosis.
Thu Feb 06 00:00:00 EST 2014
Cdk5-mediated phosphorylation of RapGEF2 controls neuronal migration in the developing cerebral cortex.
Nature communications
Ye T,Ip JP,Fu AK,Ip NY
33-3900 was used in immunohistochemistry - frozen section to study the initiation and regulation of radial migration.
Fri Sep 05 00:00:00 EDT 2014
TRPV2 is critical for the maintenance of cardiac structure and function in mice.
Nature communications
Katanosaka Y,Iwasaki K,Ujihara Y,Takatsu S,Nishitsuji K,Kanagawa M,Sudo A,Toda T,Katanosaka K,Mohri S,Naruse K
33-3900 was used in immunohistochemistry - frozen section to elucidate the critical role of TRPV2 in maintenance of cardiac function and structure in mice
Thu May 29 00:00:00 EDT 2014
Further evidence that E-cadherin is not a tumour suppressor gene in invasive ductal carcinoma of the breast: an immunohistochemical study.
Histopathology
Rakha EA,Teoh TK,Lee AH,Nolan CC,Ellis IO,Green AR
33-3900 was used in immunohistochemistry to examine E-cadherin-negative ductal carcinoma.
Mon Apr 01 00:00:00 EDT 2013
Cardiovascular dysregulation of miR-17-92 causes a lethal hypertrophic cardiomyopathy and arrhythmogenesis.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Danielson LS,Park DS,Rotllan N,Chamorro-Jorganes A,Guijarro MV,Fernandez-Hernando C,Fishman GI,Phoon CK,Hernando E
33-3900 was used in immunohistochemistry to study the development of fatal cardiac hypertrophy and arrrhythmia in mice overexpressing miRNA-17-92 in heart and smooth muscle
Mon Apr 01 00:00:00 EDT 2013
Toward a molecular pathologic classification of urothelial carcinoma.
The American journal of pathology
Sjödahl G,Lövgren K,Lauss M,Patschan O,Gudjonsson S,Chebil G,Aine M,Eriksson P,Månsson W,Lindgren D,Fernö M,Liedberg F,Höglund M
33-3900 was used in immunohistochemistry (paraffin) to describe the molecular pathologic characteristics of urothelial carcinomas subtypes.
Sun Sep 01 00:00:00 EDT 2013
A three-dimensional microenvironment alters protein expression and chemosensitivity of epithelial ovarian cancer cells in vitro.
Laboratory investigation; a journal of technical methods and pathology
Lee JM,Mhawech-Fauceglia P,Lee N,Parsanian LC,Lin YG,Gayther SA,Lawrenson K
33-3900 was used in western blot to compare the histological, biological, and molecular features of 2D and 3D epithelial ovarian cancer cultures.
Wed May 01 00:00:00 EDT 2013
The Xin repeat-containing protein, mXinβ, initiates the maturation of the intercalated discs during postnatal heart development.
Developmental biology
Wang Q,Lin JL,Chan SY,Lin JJ
33-3900 was used in western blot to study the intercalated disc of the heart.
Fri Feb 15 00:00:00 EST 2013
Isolation and characterization of a primary proximal tubular epithelial cell model from human kidney by CD10/CD13 double labeling.
PloS one
Van der Hauwaert C,Savary G,Gnemmi V,Glowacki F,Pottier N,Bouillez A,Maboudou P,Zini L,Leroy X,Cauffiez C,Perrais M,Aubert S
33-3900 was used in Western Blotting to describe a method for establishing a robust renal proximal tubular epithelial cell model suitable for further experimentation.
Thu Jan 30 00:00:00 EST 2014
Three-dimensional cell culturing by magnetic levitation.
Nature protocols
Haisler WL,Timm DM,Gage JA,Tseng H,Killian TC,Souza GR
33-3900 was used in immunohistochemistry to describe the magnetic levitation method of 3D cell culturing.
Tue Oct 01 00:00:00 EDT 2013
Cadherin-11 contributes to pulmonary fibrosis: potential role in TGF-β production and epithelial to mesenchymal transition.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Schneider DJ,Wu M,Le TT,Cho SH,Brenner MB,Blackburn MR,Agarwal SK
Wed Feb 01 00:00:00 EST 2012
Cadherin-11 contributes to pulmonary fibrosis: potential role in TGF-β production and epithelial to mesenchymal transition.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Schneider DJ,Wu M,Le TT,Cho SH,Brenner MB,Blackburn MR,Agarwal SK
Wed Feb 01 00:00:00 EST 2012
Immunohistochemical study of the epithelial-mesenchymal transition phenotype in cancer of unknown primary: incidence, correlations and prognostic utility.
Anticancer research
Stoyianni A,Goussia A,Pentheroudakis G,Siozopoulou V,Ioachim E,Krikelis D,Golfinopoulos V,Cervantes A,Bobos M,Fotsis T,Bellou S,Fountzilas G,Malamou-Mitsi V,Pavlidis N
33-3900 was used in immunohistochemistry (paraffin) to assess the incidence and prognostic significance of the epithelial to mesenchymal transition in cancer of unknown primary.
Sun Apr 01 00:00:00 EDT 2012
Analysis of a Jup hypomorphic allele reveals a critical threshold for postnatal viability.
Genesis (New York, N.Y. : 2000)
Swope D,Li J,Muller EJ,Radice GL
33-3900 was used in western blot to study plakoglobin using hypomorphic mice.
Mon Oct 01 00:00:00 EDT 2012
N-cadherin in neuroblastoma disease: expression and clinical significance.
PloS one
Lammens T,Swerts K,Derycke L,De Craemer A,De Brouwer S,De Preter K,Van Roy N,Vandesompele J,Speleman F,Philippé J,Benoit Y,Beiske K,Bracke M,Laureys G
33-3900 was used in Immunocytochemistry to study the expression of N-cadherin in neuroblastoma tumours and cell lines.
Mon Jun 18 00:00:00 EDT 2012
E/N-cadherin switch mediates cancer progression via TGF-β-induced epithelial-to-mesenchymal transition in extrahepatic cholangiocarcinoma.
British journal of cancer
Araki K,Shimura T,Suzuki H,Tsutsumi S,Wada W,Yajima T,Kobayahi T,Kubo N,Kuwano H
33-3900 was used in Immunohistochemistry on paraffin embedded tissues to show cadherin switch promotes cancer progression via TGF-Β-induced EMT in extrahepatic CC, suggesting a target for elucidating the mechanisms of invasion and metastasis in extrahepatic CC.
Tue Dec 06 00:00:00 EST 2011
Adipose tissue-derived stem cell in vitro differentiation in a three-dimensional dental bud structure.
The American journal of pathology
Ferro F,Spelat R,Falini G,Gallelli A,D'Aurizio F,Puppato E,Pandolfi M,Beltrami AP,Cesselli D,Beltrami CA,Ambesi-Impiombato FS,Curcio F
33-3900 was used in immunohistochemistry - paraffin section to use adipose tissue-derived stem cells to generate dental buds.
Sun May 01 00:00:00 EDT 2011
ZO-1 determines adherens and gap junction localization at intercalated disks.
American journal of physiology. Heart and circulatory physiology
Palatinus JA,O'Quinn MP,Barker RJ,Harris BS,Jourdan J,Gourdie RG
33-3900 was used in immunoprecipitation to study the contribution of ZO-1 to cell-cell junction localization
Tue Feb 01 00:00:00 EST 2011
A novel gelatin hydrogel carrier sheet for corneal endothelial transplantation.
Tissue engineering. Part A
Watanabe R,Hayashi R,Kimura Y,Tanaka Y,Kageyama T,Hara S,Tabata Y,Nishida K
33-3900 was used in immunocytochemistry to describe a method to cultivate corneal endothelial cells for transplantation.
Thu Sep 01 00:00:00 EDT 2011
Rac1 GTPase-deficient mouse lens exhibits defects in shape, suture formation, fiber cell migration and survival.
Developmental biology
Maddala R,Chauhan BK,Walker C,Zheng Y,Robinson ML,Lang RA,Rao PV
33-3900 was used in immunohistochemistry - paraffin section and western blot to study the role of the Rac1 GTPase the shaping of the ocular lens
Thu Dec 01 00:00:00 EST 2011
Alterations of epithelial stem cell marker patterns in human diabetic corneas and effects of c-met gene therapy.
Molecular vision
Saghizadeh M,Soleymani S,Harounian A,Bhakta B,Troyanovsky SM,Brunken WJ,Pellegrini G,Ljubimov AV
33-3900 was used in immunohistochemistry to test is c-met normalizes altered limbal stem cell marker patterns in diabetic corneas
Tue Jan 10 00:00:00 EST 2012
Monoclonal antibody targeting of N-cadherin inhibits prostate cancer growth, metastasis and castration resistance.
Nature medicine
Tanaka H,Kono E,Tran CP,Miyazaki H,Yamashiro J,Shimomura T,Fazli L,Wada R,Huang J,Vessella RL,An J,Horvath S,Gleave M,Rettig MB,Wainberg ZA,Reiter RE
Wed Dec 01 00:00:00 EST 2010
The canonical NF-kappaB pathway governs mammary tumorigenesis in transgenic mice and tumor stem cell expansion.
Cancer research
Liu M,Sakamaki T,Casimiro MC,Willmarth NE,Quong AA,Ju X,Ojeifo J,Jiao X,Yeow WS,Katiyar S,Shirley LA,Joyce D,Lisanti MP,Albanese C,Pestell RG
33-3900 was used in western blot to determine the role of mammary epithelial cell NF-kapaB signaling in tumor progression in vivo.
Wed Dec 15 00:00:00 EST 2010
Granzyme B is expressed in urothelial carcinoma and promotes cancer cell invasion.
International journal of cancer
D'Eliseo D,Pisu P,Romano C,Tubaro A,De Nunzio C,Morrone S,Santoni A,Stoppacciaro A,Velotti F
33-3900 was used in immunohistochemistry to examine granzyme B and perforin expression in bladder cancer cell lines and in urothelial carcinoma tissues
Wed Sep 01 00:00:00 EDT 2010
Expression analysis of epithelial cadherin and related proteins in IBH-6 and IBH-4 human breast cancer cell lines.
Journal of cellular physiology
Lapyckyj L,Castillo LF,Matos ML,Gabrielli NM,Lüthy IA,Vazquez-Levin MH
33-3900 was used in western blot to measure expression of E-cadherin and related proteins in breast cancer cell lines
Mon Mar 01 00:00:00 EST 2010
Differential effects of testosterone and TGF-β3 on endocytic vesicle-mediated protein trafficking events at the blood-testis barrier.
Experimental cell research
Su L,Mruk DD,Lee WM,Cheng CY
33-3900 was used in immunocytochemistry and western blot to study protein trafficking in Sertoli cells
Fri Oct 15 00:00:00 EDT 2010
Exploring the peritoneal surface malignancy phenotype--a pilot immunohistochemical study of human pseudomyxoma peritonei and derived animal models.
Human pathology
Flatmark K,Davidson B,Kristian A,Stavnes HT,Førsund M,Reed W
33-3900 was used in immunohistochemistry to characterize the expression of a number of proteins in tissues from pseudomyxoma peritonei patients.
Sun Aug 01 00:00:00 EDT 2010
Variable expression of tenascin-C, osteopontin and fibronectin in inflammatory myofibroblastic tumour of the lung.
APMIS : acta pathologica, microbiologica, et immunologica Scandinavica
Kaarteenaho R,Sormunen R,Pääkkö P
33-3900 was used in immunohistochemistry - paraffin section to measure the expression of tenascin-C, osteopontin, and fibronectin in inflammatory myofibroblastic tumor of the lung
Mon Feb 01 00:00:00 EST 2010
Neural cadherin is expressed in human gametes and participates in sperm-oocyte interaction events.
International journal of andrology
Marín-Briggiler CI,Lapyckyj L,González Echeverría MF,Rawe VY,Alvarez Sedó C,Vazquez-Levin MH
33-3900 was used in western blot to determine the localization and function of N-cadherin in human spermatozoa and oocytes
Mon Feb 01 00:00:00 EST 2010
N-cadherin serves as diagnostic biomarker in intrahepatic and perihilar cholangiocarcinomas.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc
Mosnier JF,Kandel C,Cazals-Hatem D,Bou-Hanna C,Gournay J,Jarry A,Laboisse CL
33-3900 was used in immunohistochemistry - paraffin section and western blot to assess if E- and N-cadherin expression has diagnostic value for intrahepatic cholangiocarcinoma
Sun Feb 01 00:00:00 EST 2009
N-cadherin in the maintenance of human corneal limbal epithelial progenitor cells in vitro.
Investigative ophthalmology & visual science
Higa K,Shimmura S,Miyashita H,Kato N,Ogawa Y,Kawakita T,Shimazaki J,Tsubota K
33-3900 was used in Western Blotting to demonstrate the role of N-cadherin in maintaining the progenitor status of primary human limbal epithelial cells in vitro.
Thu Oct 01 00:00:00 EDT 2009
RAB13 participates in ectoplasmic specialization dynamics in the rat testis.
Biology of reproduction
Mruk DD,Lau AS
33-3900 was used in Western Blotting to demonstrate the participation of RAB-13 in the dynamics of ectoplasmic specialisation in the testis.
Sun Mar 01 00:00:00 EST 2009
The expression of Twist has an impact on survival in human bladder cancer and is influenced by the smoking status.
Urologic oncology
Fondrevelle ME,Kantelip B,Reiter RE,Chopin DK,Thiery JP,Monnien F,Bittard H,Wallerand H
33-3900 was used in immunohistochemistry - paraffin section to measure Twist and E- and N-cadherin expression in human primary bladder tumor from tobacco and non-tobacco users and evaluate their prognostic value
Thu Jul 09 00:00:00 EDT 2009
Blood-testis barrier dynamics are regulated by testosterone and cytokines via their differential effects on the kinetics of protein endocytosis and recycling in Sertoli cells.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Yan HH,Mruk DD,Lee WM,Cheng CY
Sun Jun 01 00:00:00 EDT 2008
Blood-testis barrier dynamics are regulated by testosterone and cytokines via their differential effects on the kinetics of protein endocytosis and recycling in Sertoli cells.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Yan HH,Mruk DD,Lee WM,Cheng CY
Sun Jun 01 00:00:00 EDT 2008
N-cadherin haploinsufficiency affects cardiac gap junctions and arrhythmic susceptibility.
Journal of molecular and cellular cardiology
Li J,Levin MD,Xiong Y,Petrenko N,Patel VV,Radice GL
33-3900 was used in immunohistochemistry to explore the relationship between N-cadherin and connexin43 in the heart
Sat Mar 01 00:00:00 EST 2008
JNK signaling pathway is required for bFGF-mediated surface cadherin downregulation on HUVEC.
Experimental cell research
Wu JC,Yan HC,Chen WT,Chen WH,Wang CJ,Chi YC,Kao WY
33-3900 was used in western blot to find that basic fibroblast growth factor downregulates typical cadherin expression on the surface of human umbilical vein endothelial cells via FGF receptor 1 signaling
Fri Feb 01 00:00:00 EST 2008
Coexpression of two mesenchymal cadherins, cadherin 11 and N-cadherin, on murine fibroblast-like synoviocytes.
Arthritis and rheumatism
Agarwal SK,Lee DM,Kiener HP,Brenner MB
33-3900 was used in immunocytochemistry and western blot to examine cadherin expression in mouse fibroblast-like synoviocytes
Tue Apr 01 00:00:00 EDT 2008
Bin1 ablation in mammary gland delays tissue remodeling and drives cancer progression.
Cancer research
Chang MY,Boulden J,Sutanto-Ward E,Duhadaway JB,Soler AP,Muller AJ,Prendergast GC
33-3900 was used in western blot to examine the effects of mammary gland-specific deletion of Bin1 on initiation and progression of breast cancer in mice
Mon Jan 01 00:00:00 EST 2007
Paucity of pericytes in germinal matrix vasculature of premature infants.
The Journal of neuroscience : the official journal of the Society for Neuroscience
Braun A,Xu H,Hu F,Kocherlakota P,Siegel D,Chander P,Ungvari Z,Csiszar A,Nedergaard M,Ballabh P
33-3900 was used in western blot to propose that a paucity of pericytes in the germinal matrix vasculature contributes to its propensity to hemorrhage
Wed Oct 31 00:00:00 EDT 2007
Coxsackie and adenovirus receptor (CAR) is a product of Sertoli and germ cells in rat testes which is localized at the Sertoli-Sertoli and Sertoli-germ cell interface.
Experimental cell research
Wang CQ,Mruk DD,Lee WM,Cheng CY
33-3900 was used in immunohistochemistry - frozen section to determine the distribution pattern and physiological function of coxsackie and adenovirus receptor in the testis
Sun Apr 15 00:00:00 EDT 2007
Aconitine alters connexin43 phosphorylation status and [Ca2+] oscillation patterns in cultured ventricular myocytes of neonatal rats.
Toxicology in vitro : an international journal published in association with BIBRA
Zhang SW,Liu Y,Huang GZ,Liu L
33-3900 was used in western blot to test if aconitine affects connexin43 phosphorylation and intracellular calcium oscillation patterns in cultured ventricular myocytes of neonatal rats
Sat Dec 01 00:00:00 EST 2007
Foxe3 is required for morphogenesis and differentiation of the anterior segment of the eye and is sensitive to Pax6 gene dosage.
Developmental biology
Blixt A,Landgren H,Johansson BR,Carlsson P
33-3900 was used in immunohistochemistry to compare the eye defects of dyl and Foxe3 mutant mice
Thu Feb 01 00:00:00 EST 2007
Rab4A GTPase catenin interactions are involved in cell junction dynamics in the testis.
Journal of andrology
Mruk DD,Lau AS,Sarkar O,Xia W
33-3900 was used in Western Blotting to suggest that Rab4A participates in adherens junction dynamics in the testis.
Thu Dec 27 00:00:00 EST 2007
IQ-domain GTPase-activating protein 1 regulates beta-catenin at membrane ruffles and its role in macropinocytosis of N-cadherin and adenomatous polyposis coli.
The Journal of biological chemistry
Sharma M,Henderson BR
33-3900 was used in immunocytochemistry to identify the membrane ruffle-targeting region of beta-catenin
Fri Mar 16 00:00:00 EDT 2007
N-cadherin as a novel prognostic marker of progression in superficial urothelial tumors.
Clinical cancer research : an official journal of the American Association for Cancer Research
Lascombe I,Clairotte A,Fauconnet S,Bernardini S,Wallerand H,Kantelip B,Bittard H
33-3900 was used in immunohistochemistry - paraffin section to discover if N-cadherin expression is associated with the bladder tumor progression
Mon May 01 00:00:00 EDT 2006
Notch1 signaling promotes primary melanoma progression by activating mitogen-activated protein kinase/phosphatidylinositol 3-kinase-Akt pathways and up-regulating N-cadherin expression.
Cancer research
Liu ZJ,Xiao M,Balint K,Smalley KS,Brafford P,Qiu R,Pinnix CC,Li X,Herlyn M
33-3900 was used in western blot to report that Notch1 signaling drives the vertical growth phase of primary melanoma
Sat Apr 15 00:00:00 EDT 2006
Genetic profiling of epithelial cells expressing E-cadherin repressors reveals a distinct role for Snail, Slug, and E47 factors in epithelial-mesenchymal transition.
Cancer research
Moreno-Bueno G,Cubillo E,Sarrió D,Peinado H,Rodríguez-Pinilla SM,Villa S,Bolós V,Jordá M,Fabra A,Portillo F,Palacios J,Cano A
33-3900 was used in immunohistochemistry to investigate genes regulated by Snail, Slug, and E47 transcription factors
Sun Oct 01 00:00:00 EDT 2006
Dynamin II interacts with the cadherin- and occludin-based protein complexes at the blood-testis barrier in adult rat testes.
The Journal of endocrinology
Lie PP,Xia W,Wang CQ,Mruk DD,Yan HH,Wong CH,Lee WM,Cheng CY
33-3900 was used in Immunocytochemistry-immunoflourescence to identify the interactions of dynamin II, cadherin- and occludin-based protein complexes, at the blood-testis barrier in adult rats.
Fri Dec 01 00:00:00 EST 2006
Laminin alpha 3 forms a complex with beta3 and gamma3 chains that serves as the ligand for alpha 6beta1-integrin at the apical ectoplasmic specialization in adult rat testes.
The Journal of biological chemistry
Yan HHN,Cheng CY
33-3900 was used in Immunohistochemistry-immunofluorescence to characterise the laminin chains expressed in cells of the seminiferous epithelium in the rat testes.
Fri Jun 23 00:00:00 EDT 2006
P-cadherin overexpression is an indicator of clinical outcome in invasive breast carcinomas and is associated with CDH3 promoter hypomethylation.
Clinical cancer research : an official journal of the American Association for Cancer Research
Paredes J,Albergaria A,Oliveira JT,Jerónimo C,Milanezi F,Schmitt FC
33-3900 was used in Immunohistochemistry to demonstrate that P-cadherin expression showed a strong correlation with high histologic grade, increased proliferation, c-erbB-2 and p53 expression, lack of estrogen receptor, and poor patient survival.
Mon Aug 15 00:00:00 EDT 2005
Gene expression in thyroid autonomous adenomas provides insight into their physiopathology.
Oncogene
Wattel S,Mircescu H,Venet D,Burniat A,Franc B,Frank S,Andry G,Van Sande J,Rocmans P,Dumont JE,Detours V,Maenhaut C
Thu Oct 20 00:00:00 EDT 2005
Gene expression in thyroid autonomous adenomas provides insight into their physiopathology.
Oncogene
Wattel S,Mircescu H,Venet D,Burniat A,Franc B,Frank S,Andry G,Van Sande J,Rocmans P,Dumont JE,Detours V,Maenhaut C
Thu Oct 20 00:00:00 EDT 2005
N-cadherin acts upstream of VE-cadherin in controlling vascular morphogenesis.
The Journal of cell biology
Luo Y,Radice GL
Mon Apr 11 00:00:00 EDT 2005
Disruption of Sertoli-germ cell adhesion function in the seminiferous epithelium of the rat testis can be limited to adherens junctions without affecting the blood-testis barrier integrity: an in vivo study using an androgen suppression model.
Journal of cellular physiology
Xia W,Wong CH,Lee NP,Lee WM,Cheng CY
33-3900 was used in immunohistochemistry - frozen section to study regulation of the blood-testis barrier
Sat Oct 01 00:00:00 EDT 2005
Modulating the strength of cadherin adhesion: evidence for a novel adhesion complex.
Journal of cell science
Kim YJ,Sauer C,Testa K,Wahl JK,Svoboda RA,Johnson KR,Wheelock MJ,Knudsen KA
33-3900 was used in immunocytochemistry and western blot to identify and characterize a novel classical cadherin adhesion system
Thu Sep 01 00:00:00 EDT 2005
Blood-testis barrier dynamics are regulated by {alpha}2-macroglobulin via the c-Jun N-terminal protein kinase pathway.
Endocrinology
Wong CH,Mruk DD,Siu MK,Cheng CY
33-3900 was used in Western Blotting and IHC/IF to elucidate the regulation of blood-testis barrier dynamics by alpha(2)-macroglobulin.
Fri Apr 01 00:00:00 EST 2005
Blood-testis barrier dynamics are regulated by {alpha}2-macroglobulin via the c-Jun N-terminal protein kinase pathway.
Endocrinology
Wong CH,Mruk DD,Siu MK,Cheng CY
33-3900 was used in Western Blotting and IHC/IF to elucidate the regulation of blood-testis barrier dynamics by alpha(2)-macroglobulin.
Fri Apr 01 00:00:00 EST 2005
Effect of N-cadherin misexpression by the mammary epithelium in mice.
Journal of cellular biochemistry
Knudsen KA,Sauer C,Johnson KR,Wheelock MJ
33-3900 was used in immunohistochemistry - paraffin section to investigate the effect of N-cadherin misexpression in mice
Mon Aug 15 00:00:00 EDT 2005
TGF-beta3 regulates anchoring junction dynamics in the seminiferous epithelium of the rat testis via the Ras/ERK signaling pathway: An in vivo study.
Developmental biology
Xia W,Cheng CY
33-3900 was used in immunohistochemistry - frozen section to test if TGF-beta3 regulates anchoring junction dynamics in the blood-testis barrier
Fri Apr 15 00:00:00 EDT 2005
The duality of beta-catenin function: a requirement in lens morphogenesis and signaling suppression of lens fate in periocular ectoderm.
Developmental biology
Smith AN,Miller LA,Song N,Taketo MM,Lang RA
33-3900 was used in Immunohistochemistry-immunofluorescence to investigate the cytoskeletal and signalling roles of beta-catenin during the early phases of lens development.
Thu Sep 15 00:00:00 EDT 2005
Simultaneous bilateral breast carcinoma: Histopathological characteristics and CD44/catenin-cadherin profile.
Histology and histopathology
Bassarova AV,Torlakovic E,Sedloev T,Hristova SL,Trifonov DV,Nesland JM
33-3900 was used in immunohistochemistry - paraffin section to compare clinicopathological characteristics and immunohistochemical profiles of simultaneous bilateral breast cancer and corresponding lymph node metastases
Fri Jul 01 00:00:00 EDT 2005
Connexin43 associated with an N-cadherin-containing multiprotein complex is required for gap junction formation in NIH3T3 cells.
The Journal of biological chemistry
Wei CJ,Francis R,Xu X,Lo CW
Fri May 20 00:00:00 EDT 2005
Connexin43 associated with an N-cadherin-containing multiprotein complex is required for gap junction formation in NIH3T3 cells.
The Journal of biological chemistry
Wei CJ,Francis R,Xu X,Lo CW
Fri May 20 00:00:00 EDT 2005
Connexin43 associated with an N-cadherin-containing multiprotein complex is required for gap junction formation in NIH3T3 cells.
The Journal of biological chemistry
Wei CJ,Francis R,Xu X,Lo CW
Fri May 20 00:00:00 EDT 2005
Connexin43 associated with an N-cadherin-containing multiprotein complex is required for gap junction formation in NIH3T3 cells.
The Journal of biological chemistry
Wei CJ,Francis R,Xu X,Lo CW
Fri May 20 00:00:00 EDT 2005
Sertoli-Sertoli and Sertoli-germ cell interactions and their significance in germ cell movement in the seminiferous epithelium during spermatogenesis.
Endocrine reviews
Mruk DD,Cheng CY
33-3900 was used in Immunohistochemistry-immunofluorescence to study the signalling responsible for inducing Sertoli cell tight junction disassembly, which allows for germ cell movement.
Fri Oct 01 00:00:00 EDT 2004
Immunohistochemical patterns for alpha- and beta-catenin, E- and N-cadherin expression in ovarian epithelial tumors.
Gynecologic oncology
Marques FR,Fonsechi-Carvasan GA,De Angelo Andrade LA,Böttcher-Luiz F
33-3900 was used in immunohistochemistry - paraffin section to measure the E- and N-cadherin and beta- and alpha-catenin expression in benign and malignant epithelial neoplasms of the ovary and correlate expression with tumor staging, histological grade,
Thu Jul 01 00:00:00 EDT 2004
Interactions of proteases, protease inhibitors, and the beta1 integrin/laminin gamma3 protein complex in the regulation of ectoplasmic specialization dynamics in the rat testis.
Biology of reproduction
Siu MK,Cheng CY
33-3900 was used in western blot to investigate the beta-integrin/laminin gamma3 complex, MMP-2, MT-MMP and TIMP-2 at the apical ectoplasmic specialization.
Thu Apr 01 00:00:00 EST 2004
Pilomatrix carcinoma with lymph node metastases.
Journal of cutaneous pathology
Bassarova A,Nesland JM,Sedloev T,Danielsen H,Christova S
33-3900 was used in immunohistochemistry to report on a case of pilomatrix carcinoma with lymph node metastases
Thu Apr 01 00:00:00 EST 2004
Zyxin, axin, and Wiskott-Aldrich syndrome protein are adaptors that link the cadherin/catenin protein complex to the cytoskeleton at adherens junctions in the seminiferous epithelium of the rat testis.
Journal of andrology
Lee NP,Mruk DD,Conway AM,Cheng CY
33-3900 was used in immunohistochemistry - paraffin section to investigate zyxin, axin, and Wiskott-Aldrich syndrome protein in the seminiferous epithelium
Thu Sep 30 00:00:00 EDT 2004
Alpha5beta1 integrin mediates strong tissue cohesion.
Journal of cell science
Robinson EE,Zazzali KM,Corbett SA,Foty RA
Wed Jan 15 00:00:00 EST 2003
Cadherin-mediated adhesion is essential for myofibril continuity across the plasma membrane but not for assembly of the contractile apparatus.
Journal of cell science
Luo Y,Radice GL
Tue Apr 15 00:00:00 EDT 2003
Oncoprotein profiles of primary peritoneal malignant mixed müllerian tumors.
International journal of gynecological cancer : official journal of the International Gynecological Cancer Society
Ng JS,Han AC,Edelson MI,Rosenblum NG
33-3900 was used in immunohistochemistry - paraffin section to present three cases of primary peritoneal malignant mixed mullerian tumors
Tue Mar 30 00:00:00 EST 2004
Is the cadherin/catenin complex a functional unit of cell-cell actin-based adherens junctions in the rat testis?
Biology of reproduction
Lee NP,Mruk D,Lee WM,Cheng CY
33-3900 was used in immunohistochemistry - frozen section to show that the cadherin/catenin complex is present between Sertoli and germ cells and is used for the assembly of functional adheren junctions.
Sat Feb 01 00:00:00 EST 2003
Value of E-cadherin and N-cadherin immunostaining in the diagnosis of mesothelioma.
Human pathology
Ordóñez NG
33-3900 was used in immunohistochemistry to study expression of E- and N-cadherin in mesotheliomas and adenocarcinomas.
Fri Aug 01 00:00:00 EDT 2003
Epithelial-type and neural-type cadherin expression in malignant noncarcinomatous neoplasms with epithelioid features that involve the soft tissues.
Archives of pathology & laboratory medicine
Laskin WB,Miettinen M
33-3900 was used in immunohistochemistry (paraffin) to examine epithelial-type cadherin and neural-type cadherin as diagnostic markers of malignant noncarcinomatous neoplasms.
Mon Apr 01 00:00:00 EST 2002
Remodeling the intercalated disc leads to cardiomyopathy in mice misexpressing cadherins in the heart.
Journal of cell science
Ferreira-Cornwell MC,Luo Y,Narula N,Lenox JM,Lieberman M,Radice GL
33-3900 was used in immunohistochemistry - paraffin section and western blot to explore the effect of cadherin specificity on cardiac structure and function.
Mon Apr 15 00:00:00 EDT 2002
P-cadherin expression is associated with high-grade ductal carcinoma in situ of the breast.
Virchows Archiv : an international journal of pathology
Paredes J,Milanezi F,Viegas L,Amendoeira I,Schmitt F
33-3900 was used in immunohistochemistry - paraffin section to investigate the expression of E-, N-, and P-cadherin in ductal carcinoma in situ of the breast
Tue Jan 01 00:00:00 EST 2002
Mucoepidermoid carcinoma of the thyroid: a tumour histotype characterised by P-cadherin neoexpression and marked abnormalities of E-cadherin/catenins complex.
Virchows Archiv : an international journal of pathology
Rocha AS,Soares P,Machado JC,Máximo V,Fonseca E,Franssila K,Sobrinho-Simões M
33-3900 was used in immunohistochemistry - paraffin section to investigate the relationship between primary mucoepidermoid carcinoma of the thyroid and papillary thyroid carcinoma
Wed May 01 00:00:00 EDT 2002
The Erbin PDZ domain binds with high affinity and specificity to the carboxyl termini of delta-catenin and ARVCF.
The Journal of biological chemistry
Laura RP,Witt AS,Held HA,Gerstner R,Deshayes K,Koehler MF,Kosik KS,Sidhu SS,Lasky LA
Fri Apr 12 00:00:00 EDT 2002
N-cadherin-mediated intercellular interactions promote survival and migration of melanoma cells.
Cancer research
Li G,Satyamoorthy K,Herlyn M
33-3900 was used in immunoprecipitation and western blot to assess the functional significance of N-cadherin in melanoma cells.
Tue May 01 00:00:00 EDT 2001
Abnormalities of the E-cadherin/catenin adhesion complex in classical papillary thyroid carcinoma and in its diffuse sclerosing variant.
The Journal of pathology
Rocha AS,Soares P,Seruca R,Máximo V,Matias-Guiu X,Cameselle-Teijeiro J,Sobrinho-Simões M
33-3900 was used in immunohistochemistry to describe the clinicopathological features of papillary thyroid carcinoma.
Sun Jul 01 00:00:00 EDT 2001
E-cadherin suppresses cellular transformation by inhibiting beta-catenin signaling in an adhesion-independent manner.
The Journal of cell biology
Gottardi CJ,Wong E,Gumbiner BM
33-3900 was used in western blot to examine adhesion- versus a beta-catenin signaling-dependent mechanisms of E-cadherin tumor suppressor activity.
Mon May 28 00:00:00 EDT 2001
Rescuing the N-cadherin knockout by cardiac-specific expression of N- or E-cadherin.
Development (Cambridge, England)
Luo Y,Ferreira-Cornwell M,Baldwin H,Kostetskii I,Lenox J,Lieberman M,Radice G
33-3900 was used in immunohistochemistry (paraffin) to investigate the role of N-cadherin in cardiogenesis.
Thu Feb 01 00:00:00 EST 2001
Cadherin junctions in mammary tumors.
Journal of mammary gland biology and neoplasia
Wheelock MJ,Soler AP,Knudsen KA
33-3900 was used in immunohistochemistry (paraffin) to discuss using expression of cadherins and catenins as prognosis markers for cancer.
Sun Jul 01 00:00:00 EDT 2001
Dosage requirement and allelic expression of PAX6 during lens placode formation.
Development (Cambridge, England)
van Raamsdonk CD,Tilghman SM
33-3900 was used in immunohistochemistry - paraffin section to study lens development in Pax6(Sey)(-Neu)/+ mouse embryos.
Fri Dec 01 00:00:00 EST 2000
The differential expression of N-cadherin and E-cadherin distinguishes pleural mesotheliomas from lung adenocarcinomas.
Human pathology
Peralta Soler A,Knudsen KA,Jaurand MC,Johnson KR,Wheelock MJ,Klein-Szanto AJ,Salazar H
Fri Dec 01 00:00:00 EST 1995
The differential expression of N-cadherin and E-cadherin distinguishes pleural mesotheliomas from lung adenocarcinomas.
Human pathology
Peralta Soler A,Knudsen KA,Jaurand MC,Johnson KR,Wheelock MJ,Klein-Szanto AJ,Salazar H
Fri Dec 01 00:00:00 EST 1995
