Product References
Spleen-targeted neoantigen DNA vaccine for personalized immunotherapy of hepatocellular carcinoma.
EMBO molecular medicine
Wu M,Luo Z,Cai Z,Mao Q,Li Z,Li H,Zhang C,Zhang Y,Zhong A,Wu L,Liu X
Published figure using CD45 monoclonal antibody (Product # 12-0451-82) in Flow Cytometry
Wed Oct 11 00:00:00 EDT 2023
Exosomes from umbilical cord-derived mesenchymal stem cells combined with gelatin methacryloyl inhibit vein graft restenosis by enhancing endothelial functions.
Journal of nanobiotechnology
Deng Y,Li Y,Chu Z,Dai C,Ge J
Published figure using CD45 monoclonal antibody (Product # 12-0451-82) in Flow Cytometry
Wed Oct 18 00:00:00 EDT 2023
Fibroblastic reticular cells in lymph node potentiate white adipose tissue beiging through neuro-immune crosstalk in male mice.
Nature communications
Cheong LY,Wang B,Wang Q,Jin L,Kwok KHM,Wu X,Shu L,Lin H,Chung SK,Cheng KKY,Hoo RLC,Xu A
Published figure using CD45 monoclonal antibody (Product # 12-0451-82) in Flow Cytometry
Fri Mar 03 00:00:00 EST 2023
NCR negative group 3 innate lymphoid cell (NCR- ILC3) participates in abnormal pathology of lung in cigarette smoking-induced COPD mice.
Immunity, inflammation and disease
Chu S,Ma L,Yang X,Xiao B,Liang Y,Zheng S,Li L
12-0451-82 was used in Flow cytometry/Cell sorting to investigate the role of Natural Cytotoxicity Receptor negative innate lymphoid cells (NCR- ILC3) in the pathogenesis of chronic obstructive pulmonary disease (COPD) induced by cigarette smoking.
Wed Mar 01 00:00:00 EST 2023
Impaired PPARγ activation by cadmium exacerbates infection-induced lung injury.
JCI insight
Larson-Casey JL,Liu S,Pyles JM,Lapi SE,Saleem K,Antony VB,Gonzalez ML,Crossman DK,Carter AB
12-0451-82 was used in Flow cytometry/Cell sorting to suggest that impaired activation of PPAR? in monocyte-derived macrophages exacerbates lung injury and the severity of LRTIs.
Mon May 08 00:00:00 EDT 2023
Macrophagic AMPKα1 orchestrates regenerative inflammation induced by glucocorticoids.
EMBO reports
Caratti G,Desgeorges T,Juban G,Stifel U,Fessard A,Koenen M,Caratti B,Théret M,Skurk C,Chazaud B,Tuckermann JP,Mounier R
Published figure using CD45 monoclonal antibody (Product # 12-0451-82) in Flow Cytometry
Mon Feb 06 00:00:00 EST 2023
Topical Diacerein Decreases Skin and Splenic CD11c+ Dendritic Cells in Psoriasis.
International journal of molecular sciences
Brunner SM,Ramspacher A,Rieser C,Leitner J,Heil H,Ablinger M,Tevini J,Wimmer M,Koller A,Piñón Hofbauer J,Felder TK,Bauer JW,Kofler B,Lang R,Wally V
Published figure using CD45 monoclonal antibody (Product # 12-0451-82) in Flow Cytometry
Tue Feb 21 00:00:00 EST 2023
Sox11 is enriched in myogenic progenitors but dispensable for development and regeneration of the skeletal muscle.
Skeletal muscle
Oprescu SN,Baumann N,Chen X,Sun Q,Zhao Y,Yue F,Wang H,Kuang S
12-0451-82 was used in Flow cytometry/Cell sorting to identify Sox11 as a novel myogenic differentiation marker with reduced expression in quiescent and aged MuSCs, but the specific function of Sox11 in myogenesis remains to be elucidated.
Wed Sep 13 00:00:00 EDT 2023
BRCA1 deficiency in mature CD8+ T lymphocytes impairs antitumor immunity.
Journal for immunotherapy of cancer
Wu B,Qi L,Chiang HC,Pan H,Zhang X,Greenbaum A,Stark E,Wang LJ,Chen Y,Haddad BR,Clagett D,Isaacs C,Elledge R,Horvath A,Hu Y,Li R
Published figure using CD45 monoclonal antibody (Product # 12-0451-82) in Flow Cytometry
Wed Feb 01 00:00:00 EST 2023
CD11c+ microglia promote white matter repair after ischemic stroke.
Cell death & disease
Jia J,Zheng L,Ye L,Chen J,Shu S,Xu S,Bao X,Xia S,Liu R,Xu Y,Zhang M
Published figure using CD45 monoclonal antibody (Product # 12-0451-82) in Flow Cytometry
Fri Feb 24 00:00:00 EST 2023
Group 2 Innate Lymphoid Cells Protect Mice from Abdominal Aortic Aneurysm Formation via IL5 and Eosinophils.
Advanced science (Weinheim, Baden-Wurttemberg, Germany)
Zhang Y,Liu T,Deng Z,Fang W,Zhang X,Zhang S,Wang M,Luo S,Meng Z,Liu J,Sukhova GK,Li D,McKenzie ANJ,Libby P,Shi GP,Guo J
Published figure using CD45 monoclonal antibody (Product # 12-0451-82) in Flow Cytometry
Wed Mar 01 00:00:00 EST 2023
Heliangin acts as a covalent ligand of RPS2 that disrupts pre-rRNA metabolic processes in NPM1-mutated acute myeloid leukemia.
Acta pharmaceutica Sinica. B
Feng Y,Han Y,Hu A,Qu Y,Hu Y,Wu H,Wang X,He L
12-0451-82 was used in Flow cytometry/Cell sorting to suggest a novel treatment strategy and lead compound for acute myeloid leukemia patients, especially those with NPM1 mutations.
Wed Feb 01 00:00:00 EST 2023
Enteric viruses replicate in salivary glands and infect through saliva.
Nature
Ghosh S,Kumar M,Santiana M,Mishra A,Zhang M,Labayo H,Chibly AM,Nakamura H,Tanaka T,Henderson W,Lewis E,Voss O,Su Y,Belkaid Y,Chiorini JA,Hoffman MP,Altan-Bonnet N
12-0451-82 was used in Flow cytometry/Cell sorting to uncover a new transmission route for enteric viruses with implications for therapeutics, diagnostics and importantly sanitation measures to prevent spread through saliva.
Fri Jul 01 00:00:00 EDT 2022
Enteric viruses replicate in salivary glands and infect through saliva.
Nature
Ghosh S,Kumar M,Santiana M,Mishra A,Zhang M,Labayo H,Chibly AM,Nakamura H,Tanaka T,Henderson W,Lewis E,Voss O,Su Y,Belkaid Y,Chiorini JA,Hoffman MP,Altan-Bonnet N
12-0451-82 was used in Flow cytometry/Cell sorting to uncover a new transmission route for enteric viruses with implications for therapeutics, diagnostics and importantly sanitation measures to prevent spread through saliva.
Fri Jul 01 00:00:00 EDT 2022
The ZIP8/SIRT1 axis regulates alveolar progenitor cell renewal in aging and idiopathic pulmonary fibrosis.
The Journal of clinical investigation
Liang J,Huang G,Liu X,Taghavifar F,Liu N,Wang Y,Deng N,Yao C,Xie T,Kulur V,Dai K,Burman A,Rowan SC,Weigt SS,Belperio J,Stripp B,Parks WC,Jiang D,Noble PW
Published figure using CD45 monoclonal antibody (Product # 12-0451-82) in Flow Cytometry
Wed Jun 01 00:00:00 EDT 2022
Interleukin-10 genetically modified clinical-grade mesenchymal stromal cells markedly reinforced functional recovery after spinal cord injury via directing alternative activation of macrophages.
Cellular & molecular biology letters
Gao T,Huang F,Wang W,Xie Y,Wang B
Published figure using CD45 monoclonal antibody (Product # 12-0451-82) in Flow Cytometry
Thu Mar 17 00:00:00 EDT 2022
BEX1 is a critical determinant of viral myocarditis.
PLoS pathogens
Martens CR,Dorn LE,Kenney AD,Bansal SS,Yount JS,Accornero F
Published figure using CD45 monoclonal antibody (Product # 12-0451-82) in Flow Cytometry
Tue Feb 01 00:00:00 EST 2022
GPR92 activation in islet macrophages controls β cell function in a diet-induced obesity model.
The Journal of clinical investigation
de Souza CO,Paschoal VA,Sun X,Vishvanath L,Zhang Q,Shao M,Onodera T,Chen S,Joffin N,Bueno LM,Gupta RK,Oh DY
Published figure using CD45 monoclonal antibody (Product # 12-0451-82) in Flow Cytometry
Tue Nov 01 00:00:00 EDT 2022
Mineralocorticoid receptor antagonists and glucocorticoids differentially affect skeletal muscle inflammation and pathology in muscular dystrophy.
JCI insight
Howard ZM,Gomatam CK,Rabolli CP,Lowe J,Piepho AB,Bansal SS,Accornero F,Rafael-Fortney JA
Published figure using CD45 monoclonal antibody (Product # 12-0451-82) in Flow Cytometry
Mon Oct 10 00:00:00 EDT 2022
Comparative analysis of thoracic and abdominal aortic aneurysms across the segment and species at the single-cell level.
Frontiers in pharmacology
Wu H,Xie C,Wang R,Cheng J,Xu Q,Zhao H
Published figure using CD45 monoclonal antibody (Product # 12-0451-82) in Flow Cytometry
Thu Feb 02 00:00:00 EST 2023
Microglial angiotensin type 2 receptors mediate sex-specific expression of inflammatory cytokines independently of circulating estrogen.
Glia
Garrido-Gil P,Pedrosa MA,Garcia-Garrote M,Pequeño-Valtierra A,Rodríguez-Castro J,García-Souto D,Rodríguez-Pérez AI,Labandeira-Garcia JL
Published figure using CD45 monoclonal antibody (Product # 12-0451-82) in Flow Cytometry
Thu Dec 01 00:00:00 EST 2022
Hematopoietic-Mesenchymal Signals Regulate the Properties of Mesenchymal Stem Cells.
International journal of molecular sciences
Kanazawa S,Okada H,Riu D,Mabuchi Y,Akazawa C,Iwata J,Hoshi K,Hikita A
Published figure using CD45 monoclonal antibody (Product # 12-0451-82) in Flow Cytometry
Tue Jul 26 00:00:00 EDT 2022
Gene-selective transcription promotes the inhibition of tissue reparative macrophages by TNF.
Life science alliance
Dichtl S,Sanin DE,Koss CK,Willenborg S,Petzold A,Tanzer MC,Dahl A,Kabat AM,Lindenthal L,Zeitler L,Satzinger S,Strasser A,Mann M,Roers A,Eming SA,El Kasmi KC,Pearce EJ,Murray PJ
Published figure using CD45 monoclonal antibody (Product # 12-0451-82) in Flow Cytometry
Fri Apr 01 00:00:00 EDT 2022
Intranasal delivery of a small-molecule ErbB inhibitor promotes recovery from acute and late-stage CNS inflammation.
JCI insight
Linnerbauer M,Lößlein L,Vandrey O,Tsaktanis T,Beer A,Naumann UJ,Panier F,Beyer T,Nirschl L,Kuramatsu JB,Winkler J,Quintana FJ,Rothhammer V
Published figure using CD45 monoclonal antibody (Product # 12-0451-82) in Flow Cytometry
Fri Apr 08 00:00:00 EDT 2022
A nonredundant role for T cell-derived interleukin 22 in antibacterial defense of colonic crypts.
Immunity
Zindl CL,Witte SJ,Laufer VA,Gao M,Yue Z,Janowski KM,Cai B,Frey BF,Silberger DJ,Harbour SN,Singer JR,Turner H,Lund FE,Vallance BA,Rosenberg AF,Schoeb TR,Chen JY,Hatton RD,Weaver CT
12-0451-82 was used in Flow cytometry/Cell sorting to demonstrate spatiotemporal differences in the production and action of IL-22 by ILCs and T cells during infection and reveal an indispensable role for IL-22-producing T cells in the protection of the intestinal crypts.
Tue Mar 08 00:00:00 EST 2022
Tumor collection/processing under physioxia uncovers highly relevant signaling networks and drug sensitivity.
Science advances
Kumar B,Adebayo AK,Prasad M,Capitano ML,Wang R,Bhat-Nakshatri P,Anjanappa M,Simpson E,Chen D,Liu Y,Schilder JM,Colter AB,Maguire C,Temm CJ,Sandusky G,Doud EH,Wijeratne AB,Mosley AL,Broxmeyer HE,Nakshatri H
Published figure using CD45 monoclonal antibody (Product # 12-0451-82) in Flow Cytometry
Fri Jan 14 00:00:00 EST 2022
The RNA-binding protein IMP2 drives a stromal-Th17 cell circuit in autoimmune neuroinflammation.
JCI insight
Bechara R,Amatya N,Majumder S,Zhou C,Li Y,Liu Q,McGeachy MJ,Gaffen SL
Published figure using CD45 monoclonal antibody (Product # 12-0451-82) in Flow Cytometry
Tue Feb 08 00:00:00 EST 2022
Labeling and analyzing lipid droplets in mouse muscle stem cells.
STAR protocols
Chen J,Yue F,Kuang S
12-0451-82 was used in flow cytometry to describe a protocol which includes steps for BODIPY/LipidSpot610 staining of freshly isolated MuSCs, flow cytometry cultured myoblasts, and single myofibers to label lipid droplets and subsequent analysis and quantification of fluorescence signals.
Fri Dec 16 00:00:00 EST 2022
Ultrasound combined with nanobubbles promotes systemic anticancer immunity and augments anti-PD1 efficacy.
Journal for immunotherapy of cancer
Hu J,He J,Wang Y,Zhao Y,Fang K,Dong Y,Chen Y,Zhang Y,Zhang C,Wang H,Tan J,Wang J,Zi R,Liu C,Liang H,Guo Y,Ou J
12-0451-82 was used in Flow cytometry/Cell sorting to provide a promising strategy for sensitizing poorly immunogenic solid tumors to immunotherapy in the clinic.
Tue Mar 01 00:00:00 EST 2022
Tannin coordinated nanozyme composite-based hybrid hydrogel eye drops for prophylactic treatment of multidrug-resistant Pseudomonas aeruginosa keratitis.
Journal of nanobiotechnology
Wang H,Song F,Feng J,Qi X,Ma L,Xie L,Shi W,Zhou Q
12-0451-82 was used in Flow Cytometry to reveal the potential of tannin-coordinated nanozyme composite-based hybrid hydrogel eye drops for treating infectious diseases.
Fri Oct 14 00:00:00 EDT 2022
Integrative analysis of scRNA-seq and scATAC-seq revealed transit-amplifying thymic epithelial cells expressing autoimmune regulator.
eLife
Miyao T,Miyauchi M,Kelly ST,Terooatea TW,Ishikawa T,Oh E,Hirai S,Horie K,Takakura Y,Ohki H,Hayama M,Maruyama Y,Seki T,Ishii H,Yabukami H,Yoshida M,Inoue A,Sakaue-Sawano A,Miyawaki A,Muratani M,Minoda A,Akiyama N,Akiyama T
12-0451-82 was used in Flow cytometry/Cell sorting to provide evidence for the existence of transit-amplifying Aire+mTEC precursors during the Aire+mTEC differentiation process of the postnatal thymus.
Tue May 17 00:00:00 EDT 2022
Induction of alarmin S100A8/A9 mediates activation of aberrant neutrophils in the pathogenesis of COVID-19.
Cell host & microbe
Guo Q,Zhao Y,Li J,Liu J,Yang X,Guo X,Kuang M,Xia H,Zhang Z,Cao L,Luo Y,Bao L,Wang X,Wei X,Deng W,Wang N,Chen L,Chen J,Zhu H,Gao R,Qin C,Wang X,You F
Published figure using CD45 monoclonal antibody (Product # 12-0451-82) in Flow Cytometry
Wed Feb 10 00:00:00 EST 2021
Induction of alarmin S100A8/A9 mediates activation of aberrant neutrophils in the pathogenesis of COVID-19.
Cell host & microbe
Guo Q,Zhao Y,Li J,Liu J,Yang X,Guo X,Kuang M,Xia H,Zhang Z,Cao L,Luo Y,Bao L,Wang X,Wei X,Deng W,Wang N,Chen L,Chen J,Zhu H,Gao R,Qin C,Wang X,You F
Published figure using CD45 monoclonal antibody (Product # 12-0451-82) in Flow Cytometry
Wed Feb 10 00:00:00 EST 2021
Stage-specific action of Runx1 and GATA3 controls silencing of PU.1 expression in mouse pro-T cells.
The Journal of experimental medicine
Hosokawa H,Koizumi M,Masuhara K,Romero-Wolf M,Tanaka T,Nakayama T,Rothenberg EV
Published figure using CD45 monoclonal antibody (Product # 12-0451-82) in Flow Cytometry
Mon Aug 02 00:00:00 EDT 2021
Uptake and trafficking of different sized PLGA nanoparticles by dendritic cells in imiquimod-induced psoriasis-like mice model.
Acta pharmaceutica Sinica. B
Lin Z,Xi L,Chen S,Tao J,Wang Y,Chen X,Li P,Wang Z,Zheng Y
Published figure using CD45 monoclonal antibody (Product # 12-0451-82) in Flow Cytometry
Thu Apr 01 00:00:00 EDT 2021
Mapping the origin and fate of myeloid cells in distinct compartments of the eye by single-cell profiling.
The EMBO journal
Wieghofer P,Hagemeyer N,Sankowski R,Schlecht A,Staszewski O,Amann L,Gruber M,Koch J,Hausmann A,Zhang P,Boneva S,Masuda T,Hilgendorf I,Goldmann T,Böttcher C,Priller J,Rossi FM,Lange C,Prinz M
Published figure using CD45 monoclonal antibody (Product # 12-0451-82) in Flow Cytometry
Mon Mar 15 00:00:00 EDT 2021
Ablation of lysozyme M-positive cells prevents aircraft noise-induced vascular damage without improving cerebral side effects.
Basic research in cardiology
Frenis K,Helmstädter J,Ruan Y,Schramm E,Kalinovic S,Kröller-Schön S,Bayo Jimenez MT,Hahad O,Oelze M,Jiang S,Wenzel P,Sommer CJ,Frauenknecht KBM,Waisman A,Gericke A,Daiber A,Münzel T,Steven S
Published figure using CD45 monoclonal antibody (Product # 12-0451-82) in Flow Cytometry
Fri Apr 30 00:00:00 EDT 2021
Photoreceptor protection by mesenchymal stem cell transplantation identifies exosomal MiR-21 as a therapeutic for retinal degeneration.
Cell death and differentiation
Deng CL,Hu CB,Ling ST,Zhao N,Bao LH,Zhou F,Xiong YC,Chen T,Sui BD,Yu XR,Hu CH
12-0451 was used in Flow cytometry/Cell sorting to discover that intravitreal MSCT counteracted photoreceptor apoptosis and alleviate retinal morphological and functional degeneration in a mouse model of photoreceptor loss induced by N-methyl-N-nitrosourea (MNU).
Mon Mar 01 00:00:00 EST 2021
Photoreceptor protection by mesenchymal stem cell transplantation identifies exosomal MiR-21 as a therapeutic for retinal degeneration.
Cell death and differentiation
Deng CL,Hu CB,Ling ST,Zhao N,Bao LH,Zhou F,Xiong YC,Chen T,Sui BD,Yu XR,Hu CH
12-0451 was used in Flow cytometry/Cell sorting to discover that intravitreal MSCT counteracted photoreceptor apoptosis and alleviate retinal morphological and functional degeneration in a mouse model of photoreceptor loss induced by N-methyl-N-nitrosourea (MNU).
Mon Mar 01 00:00:00 EST 2021
Loss of p53 in mesenchymal stem cells promotes alteration of bone remodeling through negative regulation of osteoprotegerin.
Cell death and differentiation
Velletri T,Huang Y,Wang Y,Li Q,Hu M,Xie N,Yang Q,Chen X,Chen Q,Shou P,Gan Y,Candi E,Annicchiarico-Petruzzelli M,Agostini M,Yang H,Melino G,Shi Y,Wang Y
12-0451 was used in Flow cytometry/Cell sorting to show by microCT that mice with p53 deletion systemically or specifically in mesenchymal cells possess significantly higher bone density than their respective littermate controls.
Fri Jan 01 00:00:00 EST 2021
Loss of p53 in mesenchymal stem cells promotes alteration of bone remodeling through negative regulation of osteoprotegerin.
Cell death and differentiation
Velletri T,Huang Y,Wang Y,Li Q,Hu M,Xie N,Yang Q,Chen X,Chen Q,Shou P,Gan Y,Candi E,Annicchiarico-Petruzzelli M,Agostini M,Yang H,Melino G,Shi Y,Wang Y
12-0451 was used in Flow cytometry/Cell sorting to show by microCT that mice with p53 deletion systemically or specifically in mesenchymal cells possess significantly higher bone density than their respective littermate controls.
Fri Jan 01 00:00:00 EST 2021
Decreased antiviral immune response within the central nervous system of aged mice is associated with increased lethality of West Nile virus encephalitis.
Aging cell
Funk KE,Arutyunov AD,Desai P,White JP,Soung AL,Rosen SF,Diamond MS,Klein RS
Published figure using CD45 monoclonal antibody (Product # 12-0451-82) in Flow Cytometry
Sun Aug 01 00:00:00 EDT 2021
Anti-adipogenic signals at the onset of obesity-related inflammation in white adipose tissue.
Cellular and molecular life sciences : CMLS
Caputo T,Tran VDT,Bararpour N,Winkler C,Aguileta G,Trang KB,Giordano Attianese GMP,Wilson A,Thomas A,Pagni M,Guex N,Desvergne B,Gilardi F
Published figure using CD45 monoclonal antibody (Product # 12-0451-82) in Flow Cytometry
Fri Jan 01 00:00:00 EST 2021
RANKL from bone marrow adipose lineage cells promotes osteoclast formation and bone loss.
EMBO reports
Hu Y,Li X,Zhi X,Cong W,Huang B,Chen H,Wang Y,Li Y,Wang L,Fang C,Guo J,Liu Y,Cui J,Cao L,Weng W,Zhou Q,Wang S,Chen X,Su J
Published figure using CD45 monoclonal antibody (Product # 12-0451-82) in Flow Cytometry
Mon Jul 05 00:00:00 EDT 2021
Macrophage polarization by MSC-derived CXCL12 determines tumor growth.
Cellular & molecular biology letters
Babazadeh S,Nassiri SM,Siavashi V,Sahlabadi M,Hajinasrollah M,Zamani-Ahmadmahmudi M
Published figure using CD45 monoclonal antibody (Product # 12-0451-82) in Flow Cytometry
Sat Jun 26 00:00:00 EDT 2021
The effects of postmortem delay on mouse and human microglia gene expression.
Glia
Heng Y,Dubbelaar ML,Marie SKN,Boddeke EWGM,Eggen BJL
Published figure using CD45 monoclonal antibody (Product # 12-0451-82) in Flow Cytometry
Thu Apr 01 00:00:00 EDT 2021
Intrinsic DNA damage repair deficiency results in progressive microglia loss and replacement.
Glia
Zhang X,Heng Y,Kooistra SM,van Weering HRJ,Brummer ML,Gerrits E,Wesseling EM,Brouwer N,Nijboer TW,Dubbelaar ML,Boddeke EWGM,Eggen BJL
Published figure using CD45 monoclonal antibody (Product # 12-0451-82) in Flow Cytometry
Mon Mar 01 00:00:00 EST 2021
Intercellular Interactions of an Adipogenic CXCL12-Expressing Stromal Cell Subset in Murine Bone Marrow.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research
Matsushita Y,Chu AKY,Ono W,Welch JD,Ono N
Published figure using CD45 monoclonal antibody (Product # 12-0451-82) in Flow Cytometry
Tue Jun 01 00:00:00 EDT 2021
Macrophage LAMTOR1 Deficiency Prevents Dietary Obesity and Insulin Resistance Through Inflammation-Induced Energy Expenditure.
Frontiers in cell and developmental biology
Ying L,Zhang M,Ma X,Si Y,Li X,Su J,Yin J,Bao Y
Published figure using CD45 monoclonal antibody (Product # 12-0451-82) in Flow Cytometry
Tue Jun 08 00:00:00 EDT 2021
Single-Cell Transcriptome Profiles Reveal Fibrocytes as Potential Targets of Cell Therapies for Abdominal Aortic Aneurysm.
Frontiers in cardiovascular medicine
Li B,Song X,Guo W,Hou Y,Hu H,Ge W,Fan T,Han Z,Li Z,Yang P,Gao R,Zhao H,Wang J
12-0451-82 was used in Flow Cytometry to determine the roles of different vascular and immune cells in abdominal aortic aneurysm formation and pathogenesis.
Wed Dec 15 00:00:00 EST 2021
Alterations of macrophage and neutrophil content in skeletal muscle of aged versus young mice.
Muscle & nerve
Kawanishi N,Machida S
Published figure using CD45 monoclonal antibody (Product # 12-0451-82) in Flow Cytometry
Thu Apr 01 00:00:00 EDT 2021
Differential activation of Ca2+ influx channels modulate stem cell potency, their proliferation/viability and tissue regeneration.
NPJ Regenerative medicine
Ahamad N,Sun Y,Nascimento Da Conceicao V,Xavier Paul Ezhilan CRD,Natarajan M,Singh BB
Published figure using CD45 monoclonal antibody (Product # 12-0451-82) in Flow Cytometry
Wed Oct 20 00:00:00 EDT 2021
Suppression of mucosal Th17 memory responses by acellular pertussis vaccines enhances nasal Bordetella pertussis carriage.
NPJ vaccines
Dubois V,Chatagnon J,Thiriard A,Bauderlique-Le Roy H,Debrie AS,Coutte L,Locht C
Published figure using CD45 monoclonal antibody (Product # 12-0451-82) in Flow Cytometry
Fri Jan 08 00:00:00 EST 2021
Suppression of mucosal Th17 memory responses by acellular pertussis vaccines enhances nasal Bordetella pertussis carriage.
NPJ vaccines
Dubois V,Chatagnon J,Thiriard A,Bauderlique-Le Roy H,Debrie AS,Coutte L,Locht C
Published figure using CD45 monoclonal antibody (Product # 12-0451-82) in Flow Cytometry
Fri Jan 08 00:00:00 EST 2021
Synergistic immunotherapy of glioblastoma by dual targeting of IL-6 and CD40.
Nature communications
Yang F,He Z,Duan H,Zhang D,Li J,Yang H,Dorsey JF,Zou W,Nabavizadeh SA,Bagley SJ,Abdullah K,Brem S,Zhang L,Xu X,Byrne KT,Vonderheide RH,Gong Y,Fan Y
Published figure using CD45 monoclonal antibody (Product # 12-0451-82) in Flow Cytometry
Tue Jun 08 00:00:00 EDT 2021
The effect of fingolimod on regulatory T cells in a mouse model of brain ischaemia.
Journal of neuroinflammation
Malone K,Diaz Diaz AC,Shearer JA,Moore AC,Waeber C
Published figure using CD45 monoclonal antibody (Product # 12-0451-82) in Flow Cytometry
Sat Jan 30 00:00:00 EST 2021
NOX4 regulates macrophage apoptosis resistance to induce fibrotic progression.
The Journal of biological chemistry
Larson-Casey JL,Gu L,Kang J,Dhyani A,Carter AB
Published figure using CD45 monoclonal antibody (Product # 12-0451-82) in Flow Cytometry
Thu Jul 01 00:00:00 EDT 2021
The IRE1/XBP1 signaling axis promotes skeletal muscle regeneration through a cell non-autonomous mechanism.
eLife
Roy A,Tomaz da Silva M,Bhat R,Bohnert KR,Iwawaki T,Kumar A
Published figure using CD45 monoclonal antibody (Product # 12-0451-82) in Flow Cytometry
Tue Nov 23 00:00:00 EST 2021
A decrease in NAD+ contributes to the loss of osteoprogenitors and bone mass with aging.
NPJ aging and mechanisms of disease
Kim HN,Ponte F,Warren A,Ring R,Iyer S,Han L,Almeida M
Published figure using CD45 monoclonal antibody (Product # 12-0451-82) in Flow Cytometry
Thu Apr 01 00:00:00 EDT 2021
Therapeutic Potential of Mesenchymal Stem Cells in a Pre-Clinical Model of Diabetic Kidney Disease and Obesity.
International journal of molecular sciences
Sávio-Silva C,Soinski-Sousa PE,Simplício-Filho A,Bastos RMC,Beyerstedt S,Rangel ÉB
Published figure using CD45 monoclonal antibody (Product # 12-0451-82) in Flow Cytometry
Thu Feb 04 00:00:00 EST 2021
G-protein-coupled receptor P2Y10 facilitates chemokine-induced CD4 T cell migration through autocrine/paracrine mediators.
Nature communications
Gurusamy M,Tischner D,Shao J,Klatt S,Zukunft S,Bonnavion R,Günther S,Siebenbrodt K,Kestner RI,Kuhlmann T,Fleming I,Offermanns S,Wettschureck N
12-0451-82 was used in Flow cytometry/Cell sorting to show that in mice lacking P2Y10 in the CD4 T cell compartment, the severity of experimental autoimmune encephalomyelitis and cutaneous contact hypersensitivity is reduced.
Tue Nov 23 00:00:00 EST 2021
G-protein-coupled receptor P2Y10 facilitates chemokine-induced CD4 T cell migration through autocrine/paracrine mediators.
Nature communications
Gurusamy M,Tischner D,Shao J,Klatt S,Zukunft S,Bonnavion R,Günther S,Siebenbrodt K,Kestner RI,Kuhlmann T,Fleming I,Offermanns S,Wettschureck N
12-0451-82 was used in Flow cytometry/Cell sorting to show that in mice lacking P2Y10 in the CD4 T cell compartment, the severity of experimental autoimmune encephalomyelitis and cutaneous contact hypersensitivity is reduced.
Tue Nov 23 00:00:00 EST 2021
Use of a Self-Delivering Anti-CCL3 FANA Oligonucleotide as an Innovative Approach to Target Inflammation after Spinal Cord Injury.
eNeuro
Pelisch N,Rosas Almanza J,Stehlik KE,Aperi BV,Kroner A
Published figure using CD45 monoclonal antibody (Product # 12-0451-82) in Flow Cytometry
Fri Jun 18 00:00:00 EDT 2021
T cell-depleting nanoparticles ameliorate bone loss by reducing activated T cells and regulating the Treg/Th17 balance.
Bioactive materials
Yang X,Zhou F,Yuan P,Dou G,Liu X,Liu S,Wang X,Jin R,Dong Y,Zhou J,Lv Y,Deng Z,Liu S,Chen X,Han Y,Jin Y
Published figure using CD45 monoclonal antibody (Product # 12-0451-82) in Flow Cytometry
Fri Oct 01 00:00:00 EDT 2021
T cell-depleting nanoparticles ameliorate bone loss by reducing activated T cells and regulating the Treg/Th17 balance.
Bioactive materials
Yang X,Zhou F,Yuan P,Dou G,Liu X,Liu S,Wang X,Jin R,Dong Y,Zhou J,Lv Y,Deng Z,Liu S,Chen X,Han Y,Jin Y
Published figure using CD45 monoclonal antibody (Product # 12-0451-82) in Flow Cytometry
Fri Oct 01 00:00:00 EDT 2021
Placenta-Expanded Stromal Cell Therapy in a Rodent Model of Simulated Weightlessness.
Cells
Rubinstein L,Paul AM,Houseman C,Abegaz M,Tabares Ruiz S,O'Neil N,Kunis G,Ofir R,Cohen J,Ronca AE,Globus RK,Tahimic CGT
Published figure using CD45 monoclonal antibody (Product # 12-0451-82) in Flow Cytometry
Mon Apr 19 00:00:00 EDT 2021
Apoptotic vesicles restore liver macrophage homeostasis to counteract type 2 diabetes.
Journal of extracellular vesicles
Zheng C,Sui B,Zhang X,Hu J,Chen J,Liu J,Wu D,Ye Q,Xiang L,Qiu X,Liu S,Deng Z,Zhou J,Liu S,Shi S,Jin Y
Published figure using CD45 monoclonal antibody (Product # 12-0451-82) in Flow Cytometry
Sat May 01 00:00:00 EDT 2021
Apoptotic vesicles restore liver macrophage homeostasis to counteract type 2 diabetes.
Journal of extracellular vesicles
Zheng C,Sui B,Zhang X,Hu J,Chen J,Liu J,Wu D,Ye Q,Xiang L,Qiu X,Liu S,Deng Z,Zhou J,Liu S,Shi S,Jin Y
Published figure using CD45 monoclonal antibody (Product # 12-0451-82) in Flow Cytometry
Sat May 01 00:00:00 EDT 2021
Distinct skeletal stem cell types orchestrate long bone skeletogenesis.
eLife
Ambrosi TH,Sinha R,Steininger HM,Hoover MY,Murphy MP,Koepke LS,Wang Y,Lu WJ,Morri M,Neff NF,Weissman IL,Longaker MT,Chan CK
Published figure using CD45 monoclonal antibody (Product # 12-0451-82) in Flow Cytometry
Mon Jul 19 00:00:00 EDT 2021
Integrated OMICs unveil the bone-marrow microenvironment in human leukemia.
Cell reports
Passaro D,Garcia-Albornoz M,Diana G,Chakravarty P,Ariza-McNaughton L,Batsivari A,Borràs-Eroles C,Abarrategi A,Waclawiczek A,Ombrato L,Malanchi I,Gribben J,Bonnet D
Published figure using CD45 monoclonal antibody (Product # 12-0451-82) in Flow Cytometry
Tue May 11 00:00:00 EDT 2021
PTENα functions as an immune suppressor and promotes immune resistance in PTEN-mutant cancer.
Nature communications
Sun Y,Lu D,Yin Y,Song J,Liu Y,Hao W,Qi F,Zhang G,Zhang X,Liu L,Lin Z,Liang H,Zhao X,Jin Y,Yin Y
Published figure using CD45 monoclonal antibody (Product # 12-0451-82) in Flow Cytometry
Thu Aug 26 00:00:00 EDT 2021
Cardiac-derived TGF-β1 confers resistance to diet-induced obesity through the regulation of adipocyte size and function.
Molecular metabolism
Longenecker JZ,Petrosino JM,Martens CR,Hinger SA,Royer CJ,Dorn LE,Branch DA,Serrano J,Stanford KI,Kyriazis GA,Baskin KK,Accornero F
Published figure using CD45 monoclonal antibody (Product # 12-0451-82) in Flow Cytometry
Wed Dec 01 00:00:00 EST 2021
Determining the effect of aging, recovery time, and post-stroke memantine treatment on delayed thalamic gliosis after cortical infarct.
Scientific reports
Kim GS,Stephenson JM,Al Mamun A,Wu T,Goss MG,Min JW,Li J,Liu F,Marrelli SP
Published figure using CD45 monoclonal antibody (Product # 12-0451-82) in Flow Cytometry
Tue Jun 15 00:00:00 EDT 2021
Cytochrome P450 26A1 Modulates the Polarization of Uterine Macrophages During the Peri-Implantation Period.
Frontiers in immunology
Ji WH,Li DD,Wei DP,Gu AQ,Yang Y,Peng JP
Published figure using CD45 monoclonal antibody (Product # 12-0451-82) in Flow Cytometry
Thu Feb 10 00:00:00 EST 2022
A molybdenum oxide-based degradable nanosheet for combined chemo-photothermal therapy to improve tumor immunosuppression and suppress distant tumors and lung metastases.
Journal of nanobiotechnology
Qiu N,Yang X,Zhang Y,Zhang J,Ji J,Zhang Y,Kong X,Xi Y,Liu D,Ye L,Zhai G
Published figure using CD45 monoclonal antibody (Product # 12-0451-82) in Flow Cytometry
Sun Dec 19 00:00:00 EST 2021
Visceral adipose tissue imparts peripheral macrophage influx into the hypothalamus.
Journal of neuroinflammation
Chen KE,Lainez NM,Nair MG,Coss D
Published figure using CD45 monoclonal antibody (Product # 12-0451-82) in Flow Cytometry
Mon Jun 21 00:00:00 EDT 2021
Quantitative in vivo assessment of amyloid-beta phagocytic capacity in an Alzheimer's disease mouse model.
STAR protocols
Lau SF,Wu W,Seo H,Fu AKY,Ip NY
Published figure using CD45 monoclonal antibody (Product # 12-0451-82) in Flow Cytometry
Fri Mar 19 00:00:00 EDT 2021
Mice with induced pulmonary morbidities display severe lung inflammation and mortality following exposure to SARS-CoV-2.
JCI insight
Falach R,Bar-On L,Lazar S,Kadar T,Mazor O,Aftalion M,Gur D,Evgy Y,Shifman O,Aminov T,Israeli O,Cohen-Gihon I,Zaide G,Gutman H,Vagima Y,Makdasi E,Stein D,Rosenfeld R,Alcalay R,Zahavy E,Levy H,Glinert I,Ben-Shmuel A,Israely T,Melamed S,Politi B,Achdout H,Yitzhaki S,Kronman C,Sabo T
Published figure using CD45 monoclonal antibody (Product # 12-0451-82) in Flow Cytometry
Tue Jun 22 00:00:00 EDT 2021
The AP-1 Transcription Factor Fosl-2 Regulates Autophagy in Cardiac Fibroblasts during Myocardial Fibrogenesis.
International journal of molecular sciences
Seidenberg J,Stellato M,Hukara A,Ludewig B,Klingel K,Distler O,Błyszczuk P,Kania G
12-0451-82 was used in Flow Cytometry to demonstrate that Fosl-2 regulates autophagocytosis and the TGF-β-Fosl-2-autophagy axis controls differentiation of cardiac fibroblasts.
Sat Feb 13 00:00:00 EST 2021
A two-adjuvant multiantigen candidate vaccine induces superior protective immune responses against SARS-CoV-2 challenge.
Cell reports
Jiang W,Shi L,Cai L,Wang X,Li J,Li H,Liang J,Gu Q,Ji G,Li J,Liu L,Sun M
12-0451-82 was used in Flow cytometry/Cell sorting to suggest that the developed vaccine can elicit a multifaceted immune response and induce robust viral clearance in the URT, which makes it a potential vaccine for preventing disease and infection of SARS-CoV-2.
Tue Dec 14 00:00:00 EST 2021
Chronic stress physically spares but functionally impairs innate-like invariant T cells.
Cell reports
Rudak PT,Choi J,Parkins KM,Summers KL,Jackson DN,Foster PJ,Skaro AI,Leslie K,McAlister VC,Kuchroo VK,Inoue W,Lantz O,Haeryfar SMM
12-0451-82 was used in Flow Cytometry to report that long-term stress surprisingly abrogates both T helper 1 (TH1)- and TH2-type responses orchestrated by invariant natural killer T (iNKT) cells.
Tue Apr 13 00:00:00 EDT 2021
The ESCRT-0 subcomplex component Hrs/Hgs is a master regulator of myogenesis via modulation of signaling and degradation pathways.
BMC biology
Coudert L,Osseni A,Gangloff YG,Schaeffer L,Leblanc P
12-0451-82 was used in Flow Cytometry to show for the first time that Hrs/Hgs is a master regulator that modulates myogenesis at different levels through the control of trafficking, signaling, and degradation pathways.
Fri Jul 30 00:00:00 EDT 2021
CCR2 deficiency alters activation of microglia subsets in traumatic brain injury.
Cell reports
Somebang K,Rudolph J,Imhof I,Li L,Niemi EC,Shigenaga J,Tran H,Gill TM,Lo I,Zabel BA,Schmajuk G,Wipke BT,Gyoneva S,Jandreski L,Craft M,Benedetto G,Plowey ED,Charo I,Campbell J,Ye CJ,Panter SS,Nakamura MC,Eckalbar W,Hsieh CL
12-0451-82 was used in Flow cytometry/Cell sorting to define the heterogeneity of microglia and macrophage phenotypes during TBI in wild-type (WT) mice and Ccr2-/- mice, which lack macrophage influx following TBI and are resistant to brain damage.
Tue Sep 21 00:00:00 EDT 2021
Inhibition of the Inflammasome Activity of NLRP3 Attenuates HDM-Induced Allergic Asthma.
Frontiers in immunology
Ma M,Li G,Qi M,Jiang W,Zhou R
12-0451-82 was used in Flow Cytometry to show that NLRP3 in myeloid cells promoted the development and progression of allergic asthma in an inflammasome-dependent manner.
Fri Dec 17 00:00:00 EST 2021
Epinephrine Production in Th17 Cells and Experimental Autoimmune Encephalitis.
Frontiers in immunology
Yang P,Tian H,Zou YR,Chambon P,Ichinose H,Honig G,Diamond B,Kim SJ
Published figure using CD45 monoclonal antibody (Product # 12-0451-82) in Flow Cytometry
Mon Jul 05 00:00:00 EDT 2021
Targeting aberrant DNA methylation in mesenchymal stromal cells as a treatment for myeloma bone disease.
Nature communications
Garcia-Gomez A,Li T,de la Calle-Fabregat C,Rodríguez-Ubreva J,Ciudad L,Català-Moll F,Godoy-Tena G,Martín-Sánchez M,San-Segundo L,Muntión S,Morales X,Ortiz-de-Solórzano C,Oyarzabal J,San José-Enériz E,Esteller M,Agirre X,Prosper F,Garayoa M,Ballestar E
12-0451-82 was used in Flow Cytometry to study the efficacy of targeting methylation in myeloma bone disease.
Mon Jan 18 00:00:00 EST 2021
Systemic administration of β-glucan induces immune training in microglia.
Journal of neuroinflammation
Heng Y,Zhang X,Borggrewe M,van Weering HRJ,Brummer ML,Nijboer TW,Joosten LAB,Netea MG,Boddeke EWGM,Laman JD,Eggen BJL
Published figure using CD45 monoclonal antibody (Product # 12-0451-82) in Flow Cytometry
Mon Feb 22 00:00:00 EST 2021
Loss of microglial SIRPα promotes synaptic pruning in preclinical models of neurodegeneration.
Nature communications
Ding X,Wang J,Huang M,Chen Z,Liu J,Zhang Q,Zhang C,Xiang Y,Zen K,Li L
12-0451-82 was used in Flow cytometry/Cell sorting to investigate the role of SIRPα in neurodegeneration.
Thu Apr 01 00:00:00 EDT 2021
Inducible T-Cell Costimulator Mediates Lymphocyte/Macrophage Interactions During Liver Repair.
Frontiers in immunology
Ramavath NN,Gadipudi LL,Provera A,Gigliotti LC,Boggio E,Bozzola C,Albano E,Dianzani U,Sutti S
12-0451-82 was used in Flow cytometry/Cell sorting to demonstrated that CD8+ T-lymphocytes play a key role in supporting the survival of reparative MoMFs during liver healing trough ICOS/ICOSL-mediated signaling.
Mon Feb 14 00:00:00 EST 2022
Microglia Require CD4 T Cells to Complete the Fetal-to-Adult Transition.
Cell
Pasciuto E,Burton OT,Roca CP,Lagou V,Rajan WD,Theys T,Mancuso R,Tito RY,Kouser L,Callaerts-Vegh Z,de la Fuente AG,Prezzemolo T,Mascali LG,Brajic A,Whyte CE,Yshii L,Martinez-Muriana A,Naughton M,Young A,Moudra A,Lemaitre P,Poovathingal S,Raes J,De Strooper B,Fitzgerald DC,Dooley J,Liston A
12-0451 was used in Flow cytometry/Cell sorting to investigate the function of brain-resident CD4 T cells.
Thu Aug 06 00:00:00 EDT 2020
Macrophages Maintain Epithelium Integrity by Limiting Fungal Product Absorption.
Cell
Chikina AS,Nadalin F,Maurin M,San-Roman M,Thomas-Bonafos T,Li XV,Lameiras S,Baulande S,Henri S,Malissen B,Lacerda Mariano L,Barbazan J,Blander JM,Iliev ID,Matic Vignjevic D,Lennon-Duménil AM
Published figure using CD45 monoclonal antibody (Product # 12-0451-82) in Flow Cytometry
Thu Oct 15 00:00:00 EDT 2020
CD81 Controls Beige Fat Progenitor Cell Growth and Energy Balance via FAK Signaling.
Cell
Oguri Y,Shinoda K,Kim H,Alba DL,Bolus WR,Wang Q,Brown Z,Pradhan RN,Tajima K,Yoneshiro T,Ikeda K,Chen Y,Cheang RT,Tsujino K,Kim CR,Greiner VJ,Datta R,Yang CD,Atabai K,McManus MT,Koliwad SK,Spiegelman BM,Kajimura S
12-0451-82 was used in Flow Cytometry to investigate if CD81 functions as a key sensor of external inputs and if it controls beige adipocyte progenitor cells proliferation and whole-body energy homeostasis.
Thu Aug 06 00:00:00 EDT 2020
The Cytokine TGF-β Induces Interleukin-31 Expression from Dermal Dendritic Cells to Activate Sensory Neurons and Stimulate Wound Itching.
Immunity
Xu J,Zanvit P,Hu L,Tseng PY,Liu N,Wang F,Liu O,Zhang D,Jin W,Guo N,Han Y,Yin J,Cain A,Hoon MA,Wang S,Chen W
Published figure using CD45 monoclonal antibody (Product # 12-0451-82) in Flow Cytometry
Tue Aug 18 00:00:00 EDT 2020
STAT3-BDNF-TrkB signalling promotes alveolar epithelial regeneration after lung injury.
Nature cell biology
Paris AJ,Hayer KE,Oved JH,Avgousti DC,Toulmin SA,Zepp JA,Zacharias WJ,Katzen JB,Basil MC,Kremp MM,Slamowitz AR,Jayachandran S,Sivakumar A,Dai N,Wang P,Frank DB,Eisenlohr LC,Cantu E,Beers MF,Weitzman MD,Morrisey EE,Worthen GS
12-0451 was used in Flow cytometry/Cell sorting to elucidate repair mechanisms of proliferation and trandifferentiation of type II alveolar pneumocytes (AT2 cells) into type I alveolar pneumocytes (AT1 cells) after acute lung injury.
Thu Oct 01 00:00:00 EDT 2020
Peripherally derived angiotensin converting enzyme-enhanced macrophages alleviate Alzheimer-related disease.
Brain : a journal of neurology
Koronyo-Hamaoui M,Sheyn J,Hayden EY,Li S,Fuchs DT,Regis GC,Lopes DHJ,Black KL,Bernstein KE,Teplow DB,Fuchs S,Koronyo Y,Rentsendorj A
12-0451 was used in Flow cytometry/Cell sorting to explore the impact of selective and transient angiotensin-converting enzyme overexpression on macrophage behaviour and the relative contribution of bone marrow-derived ACE10 macrophages, but not microglia, in attenuating disease progression.
Wed Jan 01 00:00:00 EST 2020
Exposure to diesel exhaust particles increases susceptibility to invasive pneumococcal disease.
The Journal of allergy and clinical immunology
Shears RK,Jacques LC,Naylor G,Miyashita L,Khandaker S,Lebre F,Lavelle EC,Grigg J,French N,Neill DR,Kadioglu A
Published figure using CD45 monoclonal antibody (Product # 12-0451-82) in Flow Cytometry
Wed Apr 01 00:00:00 EDT 2020
Autophagic Degradation of NBR1 Restricts Metastatic Outgrowth during Mammary Tumor Progression.
Developmental cell
Marsh T,Kenific CM,Suresh D,Gonzalez H,Shamir ER,Mei W,Tankka A,Leidal AM,Kalavacherla S,Woo K,Werb Z,Debnath J
12-0451 was used in Flow cytometry/Cell sorting to reveal that autophagy gene expression inversely correlates with pro-metastatic differentiation signatures and predicts overall and distant metastasis-free survival.
Mon Mar 09 00:00:00 EDT 2020
Modulation of the functions of myeloid-derived suppressor cells : a new strategy of hydrogen sulfide anti-cancer effects.
British journal of pharmacology
De Cicco P,Ercolano G,Rubino V,Terrazzano G,Ruggiero G,Cirino G,Ianaro A
Published figure using CD45 monoclonal antibody (Product # 12-0451-82) in Flow Cytometry
Sat Feb 01 00:00:00 EST 2020
Murine Epidermal Ceramide Synthase 4 Is a Key Regulator of Skin Barrier Homeostasis.
The Journal of investigative dermatology
Peters F,Tellkamp F,Brodesser S,Wachsmuth E,Tosetti B,Karow U,Bloch W,Utermöhlen O,Krönke M,Niessen CM
12-0451-82 was used in Flow Cytometry to show that epidermal loss of ceramide synthase 4 first disturbs epidermal lipid metabolism and adult epidermal barrier function, ultimately resulting in chronic skin barrier disease characterized by acanthosis, hyperkeratosis, and immune cell accumulation.
Thu Oct 01 00:00:00 EDT 2020
Membrane expression of the estrogen receptor ERα is required for intercellular communications in the mammary epithelium.
Development (Cambridge, England)
Gagniac L,Rusidzé M,Boudou F,Cagnet S,Adlanmerini M,Jeannot P,Gaide N,Giton F,Besson A,Weyl A,Gourdy P,Raymond-Letron I,Arnal JF,Brisken C,Lenfant F
Published figure using CD45 monoclonal antibody (Product # 12-0451-82) in Flow Cytometry
Wed Mar 11 00:00:00 EDT 2020
Dysfunction of B Cell Leading to Failure of Immunoglobulin Response Is Ameliorated by Dietary Silk Peptide in 14-Month-Old C57BL/6 Mice.
Frontiers in nutrition
Chei S,Oh HJ,Lee K,Jin H,Lee JY,Lee BY
12-0451 was used in Flow cytometry/Cell sorting to study the deleterious roles of immunosenescent cells in the immune system.
Fri Dec 18 00:00:00 EST 2020
Dysfunction of B Cell Leading to Failure of Immunoglobulin Response Is Ameliorated by Dietary Silk Peptide in 14-Month-Old C57BL/6 Mice.
Frontiers in nutrition
Chei S,Oh HJ,Lee K,Jin H,Lee JY,Lee BY
12-0451 was used in Flow cytometry/Cell sorting to study the deleterious roles of immunosenescent cells in the immune system.
Fri Dec 18 00:00:00 EST 2020
Sema3A and HIF1α co-overexpressed iPSC-MSCs/HA scaffold facilitates the repair of calvarial defect in a mouse model.
Journal of cellular physiology
Li J,Wang T,Li C,Wang Z,Wang P,Zheng L
Published figure using CD45 monoclonal antibody (Product # 12-0451-82) in Flow Cytometry
Thu Oct 01 00:00:00 EDT 2020
Sema3A and HIF1α co-overexpressed iPSC-MSCs/HA scaffold facilitates the repair of calvarial defect in a mouse model.
Journal of cellular physiology
Li J,Wang T,Li C,Wang Z,Wang P,Zheng L
Published figure using CD45 monoclonal antibody (Product # 12-0451-82) in Flow Cytometry
Thu Oct 01 00:00:00 EDT 2020
Detection of Synaptic Proteins in Microglia by Flow Cytometry.
Frontiers in molecular neuroscience
Brioschi S,d'Errico P,Amann LS,Janova H,Wojcik SM,Meyer-Luehmann M,Rajendran L,Wieghofer P,Paolicelli RC,Biber K
Published figure using CD45 monoclonal antibody (Product # 12-0451-82) in Flow Cytometry
Tue Nov 03 00:00:00 EST 2020
Extracellular HMGB-1 activates inflammatory signaling in tendon cells and tissues.
Therapeutic advances in chronic disease
Zhang C,Gu X,Zhao G,Wang W,Shao J,Zhu J,Yuan T,Sun J,Nie D,Zhou Y
Published figure using CD45 monoclonal antibody (Product # 12-0451-82) in Flow Cytometry
Sun Apr 17 00:00:00 EDT 2022
Resveratrol rescues TNF‑α‑induced inhibition of osteogenesis in human periodontal ligament stem cells via the ERK1/2 pathway.
Molecular medicine reports
Yuan J,Wang X,Ma D,Gao H,Zheng D,Zhang J
Published figure using CD45 monoclonal antibody (Product # 12-0451-82) in Flow Cytometry
Fri May 01 00:00:00 EDT 2020
Enhancer remodeling promotes tumor-initiating activity in NRF2-activated non-small cell lung cancers.
Nature communications
Okazaki K,Anzawa H,Liu Z,Ota N,Kitamura H,Onodera Y,Alam MM,Matsumaru D,Suzuki T,Katsuoka F,Tadaka S,Motoike I,Watanabe M,Hayasaka K,Sakurada A,Okada Y,Yamamoto M,Suzuki T,Kinoshita K,Sekine H,Motohashi H
Published figure using CD45 monoclonal antibody (Product # 12-0451-82) in Flow Cytometry
Fri Nov 20 00:00:00 EST 2020
Eosinophils improve cardiac function after myocardial infarction.
Nature communications
Liu J,Yang C,Liu T,Deng Z,Fang W,Zhang X,Li J,Huang Q,Liu C,Wang Y,Yang D,Sukhova GK,Lindholt JS,Diederichsen A,Rasmussen LM,Li D,Newton G,Luscinskas FW,Liu L,Libby P,Wang J,Guo J,Shi GP
Published figure using CD45 monoclonal antibody (Product # 12-0451-82) in Flow Cytometry
Wed Dec 16 00:00:00 EST 2020
Ly6cLo non-classical monocytes promote resolution of rhesus rotavirus-mediated perinatal hepatic inflammation.
Scientific reports
Alkhani A,Levy CS,Tsui M,Rosenberg KA,Polovina K,Mattis AN,Mack M,Van Dyken S,Wang BM,Maher JJ,Nijagal A
Published figure using CD45 monoclonal antibody (Product # 12-0451-82) in Flow Cytometry
Tue Apr 28 00:00:00 EDT 2020
Stromal CCL2 Signaling Promotes Mammary Tumor Fibrosis through Recruitment of Myeloid-Lineage Cells.
Cancers
Kuziel G,Thompson V,D'Amato JV,Arendt LM
12-0451 was used in Flow cytometry/Cell sorting to suggest that chronic inflammation induced by CCL2 significantly enhances tumor growth and promotes the formation of a desmoplastic stroma through early recruitment of macrophages and fibrocytes into the tumor microenvironment.
Tue Jul 28 00:00:00 EDT 2020
Stromal CCL2 Signaling Promotes Mammary Tumor Fibrosis through Recruitment of Myeloid-Lineage Cells.
Cancers
Kuziel G,Thompson V,D'Amato JV,Arendt LM
12-0451 was used in Flow cytometry/Cell sorting to suggest that chronic inflammation induced by CCL2 significantly enhances tumor growth and promotes the formation of a desmoplastic stroma through early recruitment of macrophages and fibrocytes into the tumor microenvironment.
Tue Jul 28 00:00:00 EDT 2020
Small GTPase RAB6 deficiency promotes alveolar progenitor cell renewal and attenuates PM2.5-induced lung injury and fibrosis.
Cell death & disease
Yang L,Liu G,Li X,Xia Z,Wang Y,Lin W,Zhang W,Zhang W,Li X
Published figure using CD45 monoclonal antibody (Product # 12-0451-82) in Flow Cytometry
Sun Oct 04 00:00:00 EDT 2020
A RUNX2 stabilization pathway mediates physiologic and pathologic bone formation.
Nature communications
Kim JM,Yang YS,Park KH,Ge X,Xu R,Li N,Song M,Chun H,Bok S,Charles JF,Filhol-Cochet O,Boldyreff B,Dinter T,Yu PB,Kon N,Gu W,Takarada T,Greenblatt MB,Shim JH
Published figure using CD45 monoclonal antibody (Product # 12-0451-82) in Flow Cytometry
Fri May 08 00:00:00 EDT 2020
Analysis of the immune response to sciatic nerve injury identifies efferocytosis as a key mechanism of nerve debridement.
eLife
Kalinski AL,Yoon C,Huffman LD,Duncker PC,Kohen R,Passino R,Hafner H,Johnson C,Kawaguchi R,Carbajal KS,Jara JS,Hollis E,Geschwind DH,Segal BM,Giger RJ
Published figure using CD45 monoclonal antibody (Product # 12-0451-82) in Flow Cytometry
Wed Dec 02 00:00:00 EST 2020
Resolvin D1 supports skeletal myofiber regeneration via actions on myeloid and muscle stem cells.
JCI insight
Markworth JF,Brown LA,Lim E,Floyd C,Larouche J,Castor-Macias JA,Sugg KB,Sarver DC,Macpherson PC,Davis C,Aguilar CA,Maddipati KR,Brooks SV
Published figure using CD45 monoclonal antibody (Product # 12-0451-82) in Flow Cytometry
Thu Sep 17 00:00:00 EDT 2020
Resolvin D1 supports skeletal myofiber regeneration via actions on myeloid and muscle stem cells.
JCI insight
Markworth JF,Brown LA,Lim E,Floyd C,Larouche J,Castor-Macias JA,Sugg KB,Sarver DC,Macpherson PC,Davis C,Aguilar CA,Maddipati KR,Brooks SV
Published figure using CD45 monoclonal antibody (Product # 12-0451-82) in Flow Cytometry
Thu Sep 17 00:00:00 EDT 2020
Chronic alcohol-induced neuroinflammation involves CCR2/5-dependent peripheral macrophage infiltration and microglia alterations.
Journal of neuroinflammation
Lowe PP,Morel C,Ambade A,Iracheta-Vellve A,Kwiatkowski E,Satishchandran A,Furi I,Cho Y,Gyongyosi B,Catalano D,Lefebvre E,Fischer L,Seyedkazemi S,Schafer DP,Szabo G
Published figure using CD45 monoclonal antibody (Product # 12-0451-82) in Flow Cytometry
Fri Oct 09 00:00:00 EDT 2020
Delayed microglial depletion after spinal cord injury reduces chronic inflammation and neurodegeneration in the brain and improves neurological recovery in male mice.
Theranostics
Li Y,Ritzel RM,Khan N,Cao T,He J,Lei Z,Matyas JJ,Sabirzhanov B,Liu S,Li H,Stoica BA,Loane DJ,Faden AI,Wu J
Published figure using CD45 monoclonal antibody (Product # 12-0451-82) in Flow Cytometry
Tue Jun 01 00:00:00 EDT 2021
Inhibition of formyl peptide receptors improves the outcome in a mouse model of Alzheimer disease.
Journal of neuroinflammation
Schröder N,Schaffrath A,Welter JA,Putzka T,Griep A,Ziegler P,Brandt E,Samer S,Heneka MT,Kaddatz H,Zhan J,Kipp E,Pufe T,Tauber SC,Kipp M,Brandenburg LO
Published figure using CD45 monoclonal antibody (Product # 12-0451-82) in Flow Cytometry
Fri Apr 24 00:00:00 EDT 2020
Ovarian granulosa cell tumor characterization identifies FOXL2 as an immunotherapeutic target.
JCI insight
Pierini S,Tanyi JL,Simpkins F,George E,Uribe-Herranz M,Drapkin R,Burger R,Morgan MA,Facciabene A
Published figure using CD45 monoclonal antibody (Product # 12-0451-82) in Flow Cytometry
Thu Aug 20 00:00:00 EDT 2020
Butyrophilin-like proteins display combinatorial diversity in selecting and maintaining signature intraepithelial γδ T cell compartments.
Nature communications
Jandke A,Melandri D,Monin L,Ushakov DS,Laing AG,Vantourout P,East P,Nitta T,Narita T,Takayanagi H,Feederle R,Hayday A
Published figure using CD45 monoclonal antibody (Product # 12-0451-82) in Flow Cytometry
Tue Jul 28 00:00:00 EDT 2020
Tankyrase inhibition sensitizes melanoma to PD-1 immune checkpoint blockade in syngeneic mouse models.
Communications biology
Waaler J,Mygland L,Tveita A,Strand MF,Solberg NT,Olsen PA,Aizenshtadt A,Fauskanger M,Lund K,Brinch SA,Lycke M,Dybing E,Nygaard V,Bøe SL,Heintz KM,Hovig E,Hammarström C,Corthay A,Krauss S
Published figure using CD45 monoclonal antibody (Product # 12-0451-82) in Flow Cytometry
Fri Apr 24 00:00:00 EDT 2020
PPARγ inhibition boosts efficacy of PD-L1 Checkpoint Blockade Immunotherapy against Murine Melanoma in a sexually dimorphic manner.
International journal of biological sciences
Wu B,Sun X,Yuan B,Ge F,Gupta HB,Chiang HC,Li J,Hu Y,Curiel TJ,Li R
Published figure using CD45 monoclonal antibody (Product # 12-0451-82) in Flow Cytometry
Mon Aug 23 00:00:00 EDT 2021
A Synthetic Small Molecule F240B Decreases NLRP3 Inflammasome Activation by Autophagy Induction.
Frontiers in immunology
Wu CH,Gan CH,Li LH,Chang JC,Chen ST,Menon MP,Cheng SM,Yang SP,Ho CL,Chernikov OV,Lin CH,Lam Y,Hua KF
Published figure using CD45 monoclonal antibody (Product # 12-0451-82) in Flow Cytometry
Wed Jun 23 00:00:00 EDT 2021
CNS Immune Profiling in a Dengue Virus-Infected Immunocompetent Outbred ICR Mice Strain.
Frontiers in cellular and infection microbiology
Shen TJ,Chen CL,Jhan MK,Tseng PC,Lin CF
Published figure using CD45 monoclonal antibody (Product # 12-0451-82) in Flow Cytometry
Thu Jun 17 00:00:00 EDT 2021
Apoptotic bodies derived from mesenchymal stem cells promote cutaneous wound healing via regulating the functions of macrophages.
Stem cell research & therapy
Liu J,Qiu X,Lv Y,Zheng C,Dong Y,Dou G,Zhu B,Liu A,Wang W,Zhou J,Liu S,Liu S,Gao B,Jin Y
Published figure using CD45 monoclonal antibody (Product # 12-0451-82) in Flow Cytometry
Fri Nov 27 00:00:00 EST 2020
Phosphatase SHP1 impedes mesenchymal stromal cell immunosuppressive capacity modulated by JAK1/STAT3 and P38 signals.
Cell & bioscience
Jiang M,Ye J,Wang X,Li N,Wang Y,Shi Y
Published figure using CD45 monoclonal antibody (Product # 12-0451-82) in Flow Cytometry
Thu Apr 14 00:00:00 EDT 2022
Interferon Regulatory Factor-5 in Resident Macrophage Promotes Polycystic Kidney Disease.
Kidney360
Zimmerman KA,Huang J,He L,Revell DZ,Li Z,Hsu JS,Fitzgibbon WR,Hazard ES,Hardiman G,Mrug M,Bell PD,Yoder BK,Saigusa T
12-0451 was used in Flow cytometry/Cell sorting to suggest that Irf5 promotes inflammatory cytokine production in resident macrophages resulting in accelerated cystogenesis.
Sun Mar 01 00:00:00 EST 2020
Metastasis-initiating cells induce and exploit a fibroblast niche to fuel malignant colonization of the lungs.
Nature communications
Pein M,Insua-Rodríguez J,Hongu T,Riedel A,Meier J,Wiedmann L,Decker K,Essers MAG,Sinn HP,Spaich S,Sütterlin M,Schneeweiss A,Trumpp A,Oskarsson T
12-0451-82 was used in Flow Cytometry to show that disseminated breast cancer cells evoke phenotypic changes in lung fibroblasts, forming a supportive metastatic niche.
Fri Mar 20 00:00:00 EDT 2020
Platelets Fuel the Inflammasome Activation of Innate Immune Cells.
Cell reports
Rolfes V,Ribeiro LS,Hawwari I,Böttcher L,Rosero N,Maasewerd S,Santos MLS,Próchnicki T,Silva CMS,Wanderley CWS,Rothe M,Schmidt SV,Stunden HJ,Bertheloot D,Rivas MN,Fontes CJ,Carvalho LH,Cunha FQ,Latz E,Arditi M,Franklin BS
12-0451-82 was used in Flow Cytometry to conclude that platelets provide an additional layer of regulation of inflammasomes and IL-1-driven inflammation.
Tue May 12 00:00:00 EDT 2020
Sustained treatment of retinal vascular diseases with self-aggregating sunitinib microparticles.
Nature communications
Tsujinaka H,Fu J,Shen J,Yu Y,Hafiz Z,Kays J,McKenzie D,Cardona D,Culp D,Peterson W,Gilger BC,Crean CS,Zhang JZ,Kanan Y,Yu W,Cleland JL,Yang M,Hanes J,Campochiaro PA
12-0451-82 was used in Immunohistochemistry to report incorporation of sunitinib, a tyrosine kinase inhibitor that blocks VEGF receptors, into a non-inflammatory biodegradable polymer to generate sunitinib microparticles specially formulated to self-aggregate into a depot.
Tue Feb 04 00:00:00 EST 2020
Lung Adenocarcinoma Mouse Models Based on Orthotopic Transplantation of Syngeneic Tumor-Initiating Cells Expressing EpCAM, SCA-1, and Ly6d.
Cancers
Semba T,Sato R,Kasuga A,Suina K,Shibata T,Kohno T,Suzuki M,Saya H,Arima Y
12-0451-82 was used in Flow Cytometry to develop organoid-based orthotopic and syngeneic mouse models for studies of the pathogenesis and treatment of lung adenocarcinoma.
Thu Dec 17 00:00:00 EST 2020
Glucocorticoids Promote the Onset of Acute Experimental Colitis and Cancer by Upregulating mTOR Signaling in Intestinal Epithelial Cells.
Cancers
Zhang Z,Dong L,Jia A,Chen X,Yang Q,Wang Y,Wang Y,Liu R,Cao Y,He Y,Bi Y,Liu G
12-0451 was used in Flow cytometry/Cell sorting to indicate that glucocorticoid-induced mTOR signaling in epithelial cells is required in the early stages of acute ulcerative colitis by modulating the dynamics of innate immune cell recruitment and activation.
Sat Apr 11 00:00:00 EDT 2020
Mesenchymal Stromal Cell-Derived Exosomes Contribute to Epithelial Regeneration in Experimental Inflammatory Bowel Disease.
Cellular and molecular gastroenterology and hepatology
Barnhoorn MC,Plug L,Jonge ESMM,Molenkamp D,Bos E,Schoonderwoerd MJA,Corver WE,van der Meulen-de Jong AE,Verspaget HW,Hawinkels LJAC
Published figure using CD45 monoclonal antibody (Product # 12-0451-82) in Flow Cytometry
Mon May 10 00:00:00 EDT 2021
GDF15 Is an Inflammation-Induced Central Mediator of Tissue Tolerance.
Cell
Luan HH,Wang A,Hilliard BK,Carvalho F,Rosen CE,Ahasic AM,Herzog EL,Kang I,Pisani MA,Yu S,Zhang C,Ring AM,Young LH,Medzhitov R
12-0451 was used in Flow cytometry/Cell sorting to show that GDF15 coordinates tolerance to inflammatory damage through regulation of triglyceride metabolism.
Thu Aug 22 00:00:00 EDT 2019
Increased flux through the mevalonate pathway mediates fibrotic repair without injury.
The Journal of clinical investigation
Larson-Casey JL,Vaid M,Gu L,He C,Cai GQ,Ding Q,Davis D,Berryhill TF,Wilson LS,Barnes S,Neighbors JD,Hohl RJ,Zimmerman KA,Yoder BK,Longhini ALF,Hanumanthu VS,Surolia R,Antony VB,Carter AB
12-0451-82 was used in Flow Cytometry to increased activation of the small GTPase Rac1.
Fri Nov 01 00:00:00 EDT 2019
Single-Cell RNA Sequencing Identifies Candidate Renal Resident Macrophage Gene Expression Signatures across Species.
Journal of the American Society of Nephrology : JASN
Zimmerman KA,Bentley MR,Lever JM,Li Z,Crossman DK,Song CJ,Liu S,Crowley MR,George JF,Mrug M,Yoder BK
12-0451 was used in Flow cytometry/Cell sorting to indicate that there is a conserved population of innate immune cells across multiple species that have been defined as resident macrophages in the mouse.
Wed May 01 00:00:00 EDT 2019
The IL-6 signaling complex is a critical driver, negative prognostic factor, and therapeutic target in diffuse large B-cell lymphoma.
EMBO molecular medicine
Hashwah H,Bertram K,Stirm K,Stelling A,Wu CT,Kasser S,Manz MG,Theocharides AP,Tzankov A,Müller A
12-0451 was used in Flow cytometry/Cell sorting to show that a subset of diffuse large B-cell lymphoma(DLBCL) cases have evolved mechanisms that ensure constitutive activation of the IL-6 signaling pathway, i.e., the expression of both chains of the IL-6R, the expression of the cytokine itself, and the mutational inactivation of a negative regulator of IL-6 signaling, SOCS1.
Tue Oct 01 00:00:00 EDT 2019
The ROP16III-dependent early immune response determines the subacute CNS immune response and type III Toxoplasma gondii survival.
PLoS pathogens
Tuladhar S,Kochanowsky JA,Bhaskara A,Ghotmi Y,Chandrasekaran S,Koshy AA
Published figure using CD45 monoclonal antibody (Product # 12-0451-82) in Flow Cytometry
Tue Oct 01 00:00:00 EDT 2019
Distinct Tie2 tyrosine phosphorylation sites dictate phenotypic switching in endothelial progenitor cells.
Journal of cellular physiology
Siavashi V,Nassiri SM,Rahbarghazi R,Mohseni Z,Sharifi AM
Published figure using CD45 monoclonal antibody (Product # 12-0451-82) in Flow Cytometry
Wed May 01 00:00:00 EDT 2019
Protumoral bone marrow-derived cells migrate via Gβγ-dependent signaling pathways and exhibit a complex repertoire of RhoGEFs.
Journal of cell communication and signaling
Cervantes-Villagrana RD,Color-Aparicio VM,Reyes-Cruz G,Vázquez-Prado J
Published figure using CD45 monoclonal antibody (Product # 12-0451-82) in Flow Cytometry
Sat Jun 01 00:00:00 EDT 2019
Altered expression of leptin and leptin receptor in the development of immune-mediated aplastic anemia in mice.
Experimental and therapeutic medicine
Yin X,Yang J,Liu Y,Zhang J,Xin C,Zhao H,Wang W,Shi X,Cui Z,Li G,Zhao C,Liu X
12-0451 was used in Flow cytometry/Cell sorting to develop an aplastic anemia mouse model in order to study the role of leptin and leptin receptor in the differentiation of mesenchymal stem cells into adipocytes.
Thu Aug 01 00:00:00 EDT 2019
Antiallodynic Effects of Cannabinoid Receptor 2 (CB2R) Agonists on Retrovirus Infection-Induced Neuropathic Pain.
Pain research & management
Sheng WS,Chauhan P,Hu S,Prasad S,Lokensgard JR
Published figure using CD45 monoclonal antibody (Product # 12-0451-82) in Flow Cytometry
Mon Dec 16 00:00:00 EST 2019
Antitumor and immunomodulatory effects of a novel multitarget inhibitor, CS2164, in mouse hepatocellular carcinoma models.
Anti-cancer drugs
Zhou Y,Fu C,Kong Y,Pan D,Wang Y,Huang S,Li Z,Ning Z,Lu X,Shan S,Xin L
Published figure using CD45 monoclonal antibody (Product # 12-0451-82) in Flow Cytometry
Tue Oct 01 00:00:00 EDT 2019
Antitumor and immunomodulatory effects of a novel multitarget inhibitor, CS2164, in mouse hepatocellular carcinoma models.
Anti-cancer drugs
Zhou Y,Fu C,Kong Y,Pan D,Wang Y,Huang S,Li Z,Ning Z,Lu X,Shan S,Xin L
Published figure using CD45 monoclonal antibody (Product # 12-0451-82) in Flow Cytometry
Tue Oct 01 00:00:00 EDT 2019
CSF1R antagonism limits local restimulation of antiviral CD8+ T cells during viral encephalitis.
Journal of neuroinflammation
Funk KE,Klein RS
Published figure using CD45 monoclonal antibody (Product # 12-0451-82) in Flow Cytometry
Thu Jan 31 00:00:00 EST 2019
Autophagy regulates inflammatory programmed cell death via turnover of RHIM-domain proteins.
eLife
Lim J,Park H,Heisler J,Maculins T,Roose-Girma M,Xu M,Mckenzie B,van Lookeren Campagne M,Newton K,Murthy A
Published figure using CD45 monoclonal antibody (Product # 12-0451-82) in Flow Cytometry
Tue Jul 09 00:00:00 EDT 2019
The microRNAs miR-204 and miR-211 maintain joint homeostasis and protect against osteoarthritis progression.
Nature communications
Huang J,Zhao L,Fan Y,Liao L,Ma PX,Xiao G,Chen D
Published figure using CD45 monoclonal antibody (Product # 12-0451-82) in Flow Cytometry
Fri Jun 28 00:00:00 EDT 2019
The Sympathetic Nervous System Mitigates CNS Autoimmunity via β2-Adrenergic Receptor Signaling in Immune Cells.
Cell reports
Araujo LP,Maricato JT,Guereschi MG,Takenaka MC,Nascimento VM,de Melo FM,Quintana FJ,Brum PC,Basso AS
12-0451-82 was used in Flow Cytometry to uncover a suppressive role for the SNS in CNS autoimmunity while they identify potential targets for therapeutic intervention.
Tue Sep 17 00:00:00 EDT 2019
Lifelong n-3 Polyunsaturated Fatty Acid Exposure Modulates Size of Mammary Epithelial Cell Populations and Expression of Caveolae Resident Proteins in Fat-1 Mice.
Nutrients
Hillyer LM,Kang JX,Ma DWL
12-0451-82 was used in Flow cytometry/Cell sorting to provide mechanistic evidence by which omega-3 polyunsaturated fatty acids modifies early mammary gland development that may potentially reduce breast cancer risk later in life.
Tue Oct 15 00:00:00 EDT 2019
MDM2 inhibitor APG-115 synergizes with PD-1 blockade through enhancing antitumor immunity in the tumor microenvironment.
Journal for immunotherapy of cancer
Fang DD,Tang Q,Kong Y,Wang Q,Gu J,Fang X,Zou P,Rong T,Wang J,Yang D,Zhai Y
Published figure using CD45 monoclonal antibody (Product # 12-0451-82) in Flow Cytometry
Thu Nov 28 00:00:00 EST 2019
Muscularis Propria Macrophages Alter the Proportion of Nitrergic but Not Cholinergic Gastric Myenteric Neurons.
Cellular and molecular gastroenterology and hepatology
Cipriani G,Terhaar ML,Eisenman ST,Ji S,Linden DR,Wright AM,Sha L,Ordog T,Szurszewski JH,Gibbons SJ,Farrugia G
Published figure using CD45 monoclonal antibody (Product # 12-0451-82) in Flow Cytometry
Tue Jun 04 00:00:00 EDT 2019
Neutrophils promote CXCR3-dependent itch in the development of atopic dermatitis.
eLife
Walsh CM,Hill RZ,Schwendinger-Schreck J,Deguine J,Brock EC,Kucirek N,Rifi Z,Wei J,Gronert K,Brem RB,Barton GM,Bautista DM
Published figure using CD45 monoclonal antibody (Product # 12-0451-82) in Flow Cytometry
Mon Oct 21 00:00:00 EDT 2019
Exposure to Cigarette Smoke Augments Post-ischemic Brain Injury and Inflammation via Mobilization of Neutrophils and Monocytes.
Frontiers in immunology
Li H,Li X,Gao S,Wang D,Gao X,Li Y,Wang X,Cui Z,Ma H,Liu Q,Li M
12-0451 was used in Flow cytometry/Cell sorting to suggest that cigarette smoke-induced mobilization of peripheral neutrophils and monocytes augments ischemic brain injury.
Mon Sep 28 00:00:00 EDT 2020
Inducing cancer indolence by targeting mitochondrial Complex I is potentiated by blocking macrophage-mediated adaptive responses.
Nature communications
Kurelac I,Iommarini L,Vatrinet R,Amato LB,De Luise M,Leone G,Girolimetti G,Umesh Ganesh N,Bridgeman VL,Ombrato L,Columbaro M,Ragazzi M,Gibellini L,Sollazzo M,Feichtinger RG,Vidali S,Baldassarre M,Foriel S,Vidone M,Cossarizza A,Grifoni D,Kofler B,Malanchi I,Porcelli AM,Gasparre G
12-0451-82 was used in Flow Cytometry to demonstrate that respiratory complex I-deficient tumours survive and carry out angiogenesis, despite their inability to stabilise Hypoxia Inducible Factor-1 alpha.
Fri Feb 22 00:00:00 EST 2019
Establishing a Link between Endothelial Cell Metabolism and Vascular Behaviour in a Type 1 Diabetes Mouse Model.
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology
Silva C,Sampaio-Pinto V,Andrade S,Rodrigues I,Costa R,Guerreiro S,Carvalho E,Pinto-do-Ó P,Nascimento DS,Soares R
12-0451 was used in Flow cytometry/Cell sorting to study the angiogenic and metabolic gene expression profile of endothelial cells from a diabetes model.
Wed Apr 03 00:00:00 EDT 2019
FAK activity sustains intrinsic and acquired ovarian cancer resistance to platinum chemotherapy.
eLife
Diaz Osterman CJ,Ozmadenci D,Kleinschmidt EG,Taylor KN,Barrie AM,Jiang S,Bean LM,Sulzmaier FJ,Jean C,Tancioni I,Anderson K,Uryu S,Cordasco EA,Li J,Chen XL,Fu G,Ojalill M,Rappu P,Heino J,Mark AM,Xu G,Fisch KM,Kolev VN,Weaver DT,Pachter JA,Győrffy B,McHale MT,Connolly DC,Molinolo A,Stupack DG,Schlaepfer DD
Published figure using CD45 monoclonal antibody (Product # 12-0451-82) in Flow Cytometry
Tue Sep 03 00:00:00 EDT 2019
Expression of the Phosphatase Ppef2 Controls Survival and Function of CD8+ Dendritic Cells.
Frontiers in immunology
Zwick M,Ulas T,Cho YL,Ried C,Grosse L,Simon C,Bernhard C,Busch DH,Schultze JL,Buchholz VR,Stutte S,Brocker T
12-0451-82 was used in Flow Cytometry to suggest that Ppef2 is crucial to support survival of immature CD8+ DCs, while Ppef2 down-regulation during DC-maturation limits T cell responses.
Tue Oct 27 00:00:00 EDT 2020
Aryl hydrocarbon receptor activation modulates γδ intestinal intraepithelial lymphocytes and protects against ischemia/reperfusion injury in the murine small intestine.
Molecular medicine reports
Zhang Z,Pu A,Yu M,Xiao W,Sun L,Cai Y,Yang H
12-0451-82 was used in Flow cytometry/Cell sorting to suggest that the AhR plays an important role in protecting the small intestine from I/R and increasing the γδIEL population by decreasing apoptosis of γδIELs.
Fri Mar 01 00:00:00 EST 2019
PDGFRα+ stromal adipocyte progenitors transition into epithelial cells during lobulo-alveologenesis in the murine mammary gland.
Nature communications
Joshi PA,Waterhouse PD,Kasaian K,Fang H,Gulyaeva O,Sul HS,Boutros PC,Khokha R
Published figure using CD45 monoclonal antibody (Product # 12-0451-82) in Flow Cytometry
Mon Apr 15 00:00:00 EDT 2019
Growth Factor Screening in Dystrophic Muscles Reveals PDGFB/PDGFRB-Mediated Migration of Interstitial Stem Cells.
International journal of molecular sciences
Camps J,Grosemans H,Gijsbers R,Maes C,Sampaolesi M
Published figure using CD45 monoclonal antibody (Product # 12-0451-82) in Flow Cytometry
Tue Mar 05 00:00:00 EST 2019
Metastatic cancers promote cachexia through ZIP14 upregulation in skeletal muscle.
Nature medicine
Wang G,Biswas AK,Ma W,Kandpal M,Coker C,Grandgenett PM,Hollingsworth MA,Jain R,Tanji K,Lόpez-Pintado S,Borczuk A,Hebert D,Jenkitkasemwong S,Hojyo S,Davuluri RV,Knutson MD,Fukada T,Acharyya S
12-0451 was used in Magnetic cell separation to identify the metal-ion transporter ZRT- and IRT-like protein 14 as a critical mediator of cancer-induced cachexia.
Fri Jun 01 00:00:00 EDT 2018
A revised airway epithelial hierarchy includes CFTR-expressing ionocytes.
Nature
Montoro DT,Haber AL,Biton M,Vinarsky V,Lin B,Birket SE,Yuan F,Chen S,Leung HM,Villoria J,Rogel N,Burgin G,Tsankov AM,Waghray A,Slyper M,Waldman J,Nguyen L,Dionne D,Rozenblatt-Rosen O,Tata PR,Mou H,Shivaraju M,Bihler H,Mense M,Tearney GJ,Rowe SM,Engelhardt JF,Regev A,Rajagopal J
12-0451-82 was used in Flow Cytometry to study the cellular composition and hierarchy of the murine tracheal epithelium.
Wed Aug 01 00:00:00 EDT 2018
Mitophagy in Intestinal Epithelial Cells Triggers Adaptive Immunity during Tumorigenesis.
Cell
Ziegler PK,Bollrath J,Pallangyo CK,Matsutani T,Canli Ö,De Oliveira T,Diamanti MA,Müller N,Gamrekelashvili J,Putoczki T,Horst D,Mankan AK,Öner MG,Müller S,Müller-Höcker J,Kirchner T,Slotta-Huspenina J,Taketo MM,Reinheckel T,Dröse S,Larner AC,Wels WS,Ernst M,Greten TF,Arkan MC,Korn T,Wirth D,Greten FR
Published figure using CD45 monoclonal antibody (Product # 12-0451-82) in Flow Cytometry
Thu Jun 28 00:00:00 EDT 2018
Chanzyme TRPM7 Mediates the Ca2+ Influx Essential for Lipopolysaccharide-Induced Toll-Like Receptor 4 Endocytosis and Macrophage Activation.
Immunity
Schappe MS,Szteyn K,Stremska ME,Mendu SK,Downs TK,Seegren PV,Mahoney MA,Dixit S,Krupa JK,Stipes EJ,Rogers JS,Adamson SE,Leitinger N,Desai BN
Published figure using CD45 monoclonal antibody (Product # 12-0451-82) in Flow Cytometry
Tue Jan 16 00:00:00 EST 2018
Transformation of Accessible Chromatin and 3D Nucleome Underlies Lineage Commitment of Early T Cells.
Immunity
Hu G,Cui K,Fang D,Hirose S,Wang X,Wangsa D,Jin W,Ried T,Liu P,Zhu J,Rothenberg EV,Zhao K
12-0451 was used in Flow cytometry/Cell sorting to find that abrupt genome-wide changes at all three levels of chromatin organization occur during the transition from double-negative stage 2 (DN2) to DN3, accompanying the T lineage commitment.
Tue Feb 20 00:00:00 EST 2018
E3 Ligase VHL Promotes Group 2 Innate Lymphoid Cell Maturation and Function via Glycolysis Inhibition and Induction of Interleukin-33 Receptor.
Immunity
Li Q,Li D,Zhang X,Wan Q,Zhang W,Zheng M,Zou L,Elly C,Lee JH,Liu YC
Published figure using CD45 monoclonal antibody (Product # 12-0451-82) in Flow Cytometry
Tue Feb 20 00:00:00 EST 2018
The Lineage-Defining Transcription Factors SOX2 and NKX2-1 Determine Lung Cancer Cell Fate and Shape the Tumor Immune Microenvironment.
Immunity
Mollaoglu G,Jones A,Wait SJ,Mukhopadhyay A,Jeong S,Arya R,Camolotto SA,Mosbruger TL,Stubben CJ,Conley CJ,Bhutkar A,Vahrenkamp JM,Berrett KC,Cessna MH,Lane TE,Witt BL,Salama ME,Gertz J,Jones KB,Snyder EL,Oliver TG
12-0451 was used in Flow cytometry/Cell sorting to identify that SOX2 and NKX2-1 lineage-defining transcription factors regulate tumour immune microenvironment and determine lung cancer cell fate.
Tue Oct 16 00:00:00 EDT 2018
Early lineage segregation of multipotent embryonic mammary gland progenitors.
Nature cell biology
Wuidart A,Sifrim A,Fioramonti M,Matsumura S,Brisebarre A,Brown D,Centonze A,Dannau A,Dubois C,Van Keymeulen A,Voet T,Blanpain C
12-0451 was used in Flow cytometry/Cell sorting to study the timing and mechanisms mediating early lineage segregation of multipotent progenitors during mammary gland development.
Fri Jun 01 00:00:00 EDT 2018
Muscle Satellite Cell Cross-Talk with a Vascular Niche Maintains Quiescence via VEGF and Notch Signaling.
Cell stem cell
Verma M,Asakura Y,Murakonda BSR,Pengo T,Latroche C,Chazaud B,McLoon LK,Asakura A
Published figure using CD45 monoclonal antibody (Product # 12-0451-82) in Flow Cytometry
Thu Oct 04 00:00:00 EDT 2018
Defective germline reprogramming rewires the spermatogonial transcriptome.
Nature structural & molecular biology
Vasiliauskaitė L,Berrens RV,Ivanova I,Carrieri C,Reik W,Enright AJ,O'Carroll D
Published figure using CD45 monoclonal antibody (Product # 12-0451-82) in Flow Cytometry
Tue May 01 00:00:00 EDT 2018
11 Beta-hydroxysteroid dehydrogenase type 1 regulates synovitis, joint destruction, and systemic bone loss in chronic polyarthritis.
Journal of autoimmunity
Hardy RS,Fenton C,Croft AP,Naylor AJ,Begum R,Desanti G,Buckley CD,Lavery G,Cooper MS,Raza K
Published figure using CD45 monoclonal antibody (Product # 12-0451-82) in Flow Cytometry
Wed Aug 01 00:00:00 EDT 2018
Inhibition of the JNK/MAPK signaling pathway by myogenesis-associated miRNAs is required for skeletal muscle development.
Cell death and differentiation
Xie SJ,Li JH,Chen HF,Tan YY,Liu SR,Zhang Y,Xu H,Yang JH,Liu S,Zheng LL,Huang MB,Guo YH,Zhang Q,Zhou H,Qu LH
Published figure using CD45 monoclonal antibody (Product # 12-0451-82) in Flow Cytometry
Sat Sep 01 00:00:00 EDT 2018
Shared and independent functions of aPKCλ and Par3 in skin tumorigenesis.
Oncogene
Vorhagen S,Kleefisch D,Persa OD,Graband A,Schwickert A,Saynisch M,Leitges M,Niessen CM,Iden S
12-0451 was used in Immunohistochemistry to demonstrate that Par3 and aPKCλ cooperate to promote skin tumor initiation and progression, likely through sustaining growth, survival, and inflammatory signaling.
Sat Sep 01 00:00:00 EDT 2018
VISTA expression by microglia decreases during inflammation and is differentially regulated in CNS diseases.
Glia
Borggrewe M,Grit C,Den Dunnen WFA,Burm SM,Bajramovic JJ,Noelle RJ,Eggen BJL,Laman JD
Published figure using CD45 monoclonal antibody (Product # 12-0451-82) in Flow Cytometry
Sat Dec 01 00:00:00 EST 2018
Protease-activated receptor-2 signaling through β-arrestin-2 mediates Alternaria alkaline serine protease-induced airway inflammation.
American journal of physiology. Lung cellular and molecular physiology
Yee MC,Nichols HL,Polley D,Saifeddine M,Pal K,Lee K,Wilson EH,Daines MO,Hollenberg MD,Boitano S,DeFea KA
Published figure using CD45 monoclonal antibody (Product # 12-0451-82) in Flow Cytometry
Sat Dec 01 00:00:00 EST 2018
MyD88 is required for satellite cell-mediated myofiber regeneration in dystrophin-deficient mdx mice.
Human molecular genetics
Gallot YS,Straughn AR,Bohnert KR,Xiong G,Hindi SM,Kumar A
Published figure using CD45 monoclonal antibody (Product # 12-0451-82) in Flow Cytometry
Mon Oct 01 00:00:00 EDT 2018
High fish oil diet promotes liver inflammation and activates the complement system.
Molecular medicine reports
Jin H,Yan C,Xiao T,Yan N,Xu J,Zhou L,Zhou X,Shao Q,Xia S
12-0451 was used in Flow cytometry/Cell sorting to study the effects of a high fish oil diet in mice, thus revealing induced inflammation and activation of the complement system in the liver.
Tue May 01 00:00:00 EDT 2018
mTOR Modulates CD8+ T Cell Differentiation in Mice with Invasive Pulmonary Aspergillosis.
Open life sciences
Wang H,Xiao Y,Su L,Cui N,Liu D
Published figure using CD45 monoclonal antibody (Product # 12-0451-82) in Flow Cytometry
Mon Jan 01 00:00:00 EST 2018
MT4-MMP deficiency increases patrolling monocyte recruitment to early lesions and accelerates atherosclerosis.
Nature communications
Clemente C,Rius C,Alonso-Herranz L,Martín-Alonso M,Pollán Á,Camafeita E,Martínez F,Mota RA,Núñez V,Rodríguez C,Seiki M,Martínez-González J,Andrés V,Ricote M,Arroyo AG
Published figure using CD45 monoclonal antibody (Product # 12-0451-82) in Flow Cytometry
Fri Mar 02 00:00:00 EST 2018
Lsd1 regulates skeletal muscle regeneration and directs the fate of satellite cells.
Nature communications
Tosic M,Allen A,Willmann D,Lepper C,Kim J,Duteil D,Schüle R
Published figure using CD45 monoclonal antibody (Product # 12-0451-82) in Flow Cytometry
Thu Jan 25 00:00:00 EST 2018
Promotion of Myoblast Differentiation by Fkbp5 via Cdk4 Isomerization.
Cell reports
Ruiz-Estevez M,Staats J,Paatela E,Munson D,Katoku-Kikyo N,Yuan C,Asakura Y,Hostager R,Kobayashi H,Asakura A,Kikyo N
12-0451-82 was used in Magnetic cell separation to study the role of Fkbp5 in myogenesis.
Tue Nov 27 00:00:00 EST 2018
Diet-Induced Obesity Elicits Macrophage Infiltration and Reduction in Spine Density in the Hypothalami of Male but Not Female Mice.
Frontiers in immunology
Lainez NM,Jonak CR,Nair MG,Ethell IM,Wilson EH,Carson MJ,Coss D
Published figure using CD45 monoclonal antibody (Product # 12-0451-82) in Flow Cytometry
Wed Sep 25 00:00:00 EDT 2019
Adipocyte hypertrophy and lipid dynamics underlie mammary gland remodeling after lactation.
Nature communications
Zwick RK,Rudolph MC,Shook BA,Holtrup B,Roth E,Lei V,Van Keymeulen A,Seewaldt V,Kwei S,Wysolmerski J,Rodeheffer MS,Horsley V
Published figure using CD45 monoclonal antibody (Product # 12-0451-82) in Flow Cytometry
Tue Sep 04 00:00:00 EDT 2018
ATF3 Sustains IL-22-Induced STAT3 Phosphorylation to Maintain Mucosal Immunity Through Inhibiting Phosphatases.
Frontiers in immunology
Glal D,Sudhakar JN,Lu HH,Liu MC,Chiang HY,Liu YC,Cheng CF,Shui JW
Published figure using CD45 monoclonal antibody (Product # 12-0451-82) in Flow Cytometry
Thu Sep 26 00:00:00 EDT 2019
Stem cell factor is selectively secreted by arterial endothelial cells in bone marrow.
Nature communications
Xu C,Gao X,Wei Q,Nakahara F,Zimmerman SE,Mar J,Frenette PS
Published figure using CD45 monoclonal antibody (Product # 12-0451-82) in Flow Cytometry
Fri Jun 22 00:00:00 EDT 2018
Colorectal cancer liver metastatic growth depends on PAD4-driven citrullination of the extracellular matrix.
Nature communications
Yuzhalin AE,Gordon-Weeks AN,Tognoli ML,Jones K,Markelc B,Konietzny R,Fischer R,Muth A,O'Neill E,Thompson PR,Venables PJ,Kessler BM,Lim SY,Muschel RJ
12-0451 was used in Flow cytometry/Cell sorting to examine the potential for peptidylarginine deiminase 4-dependant citrullination to drive the progression of colorectal cancer liver metastasis.
Wed Nov 14 00:00:00 EST 2018
Rap1 deficiency-provoked paracrine dysfunction impairs immunosuppressive potency of mesenchymal stem cells in allograft rejection of heart transplantation.
Cell death & disease
Ding Y,Liang X,Zhang Y,Yi L,Shum HC,Chen Q,Chan BP,Fan H,Liu Z,Tergaonkar V,Qi Z,Tse HF,Lian Q
12-0451 was used in Flow cytometry/Cell sorting to indicate that Rap1 is essential to maintain the immunomodulatory function of MSCs.
Wed Mar 07 00:00:00 EST 2018
Borrelia burgdorferi adhere to blood vessels in the dura mater and are associated with increased meningeal T cells during murine disseminated borreliosis.
PloS one
Divan A,Casselli T,Narayanan SA,Mukherjee S,Zawieja DC,Watt JA,Brissette CA,Newell-Rogers MK
12-0451 was used in Flow cytometry/Cell sorting to demonstrate that there are aspects of Borrelia burgdorferi meningeal infection that can be modelled in laboratory mice.
Mon Aug 06 00:00:00 EDT 2018
Partial depletion of CD206-positive M2-like macrophages induces proliferation of beige progenitors and enhances browning after cold stimulation.
Scientific reports
Igarashi Y,Nawaz A,Kado T,Bilal M,Kuwano T,Yamamoto S,Sasahara M,Jiuxiang X,Inujima A,Koizumi K,Imura J,Shibahara N,Usui I,Fujisaka S,Tobe K
Published figure using CD45 monoclonal antibody (Product # 12-0451-82) in Flow Cytometry
Mon Oct 01 00:00:00 EDT 2018
A patient derived xenograft model of cervical cancer and cervical dysplasia.
PloS one
Larmour LI,Cousins FL,Teague JA,Deane JA,Jobling TW,Gargett CE
12-0451 was used in Immunohistochemistry to develop a patient derived xenograft model of cervical cancer and cervical dysplasia using the subrenal capsule.
Fri Mar 29 00:00:00 EDT 2019
Dual role of HDAC10 in lysosomal exocytosis and DNA repair promotes neuroblastoma chemoresistance.
Scientific reports
Ridinger J,Koeneke E,Kolbinger FR,Koerholz K,Mahboobi S,Hellweg L,Gunkel N,Miller AK,Peterziel H,Schmezer P,Hamacher-Brady A,Witt O,Oehme I
12-0451 was used in Flow cytometry/Cell sorting to study the role of HDAC10 in lysosomal exocytosis and DNA repair.
Tue Jul 03 00:00:00 EDT 2018
CD157 Marks Tissue-Resident Endothelial Stem Cells with Homeostatic and Regenerative Properties.
Cell stem cell
Wakabayashi T,Naito H,Suehiro JI,Lin Y,Kawaji H,Iba T,Kouno T,Ishikawa-Kato S,Furuno M,Takara K,Muramatsu F,Weizhen J,Kidoya H,Ishihara K,Hayashizaki Y,Nishida K,Yoder MC,Takakura N
12-0451-82 was used in Flow cytometry/Cell sorting to show that tissue-resident VESCs display self-renewal capacity and that vascular regeneration potential exists in peripheral blood vessels.
Thu Mar 01 00:00:00 EST 2018
Direct Activation of BAX by BTSA1 Overcomes Apoptosis Resistance in Acute Myeloid Leukemia.
Cancer cell
Reyna DE,Garner TP,Lopez A,Kopp F,Choudhary GS,Sridharan A,Narayanagari SR,Mitchell K,Dong B,Bartholdy BA,Walensky LD,Verma A,Steidl U,Gavathiotis E
12-0451 was used in Flow cytometry/Cell sorting to identify BTSA1, a pharmacologically optimised BAX activator that binds with high affinity and specificity to the N-terminal activation site and induces conformational changes to BAX leading to BAX-mediated apoptosis.
Mon Oct 09 00:00:00 EDT 2017
Differential cytokine contributions of perivascular haematopoietic stem cell niches.
Nature cell biology
Asada N,Kunisaki Y,Pierce H,Wang Z,Fernandez NF,Birbrair A,Ma'ayan A,Frenette PS
Published figure using CD45 monoclonal antibody (Product # 12-0451-82) in Flow Cytometry
Wed Mar 01 00:00:00 EST 2017
Cell-Type-Specific Chromatin States Differentially Prime Squamous Cell Carcinoma Tumor-Initiating Cells for Epithelial to Mesenchymal Transition.
Cell stem cell
Latil M,Nassar D,Beck B,Boumahdi S,Wang L,Brisebarre A,Dubois C,Nkusi E,Lenglez S,Checinska A,Vercauteren Drubbel A,Devos M,Declercq W,Yi R,Blanpain C
12-0451 was used in Flow cytometry/Cell sorting to investigate the importance of specific chromatin and transcriptional states in differentially priming tumours to epithelial-to-mesenchymal transition.
Thu Feb 02 00:00:00 EST 2017
Adipocyte Accumulation in the Bone Marrow during Obesity and Aging Impairs Stem Cell-Based Hematopoietic and Bone Regeneration.
Cell stem cell
Ambrosi TH,Scialdone A,Graja A,Gohlke S,Jank AM,Bocian C,Woelk L,Fan H,Logan DW,Schürmann A,Saraiva LR,Schulz TJ
12-0451 was used in Flow cytometry/Cell sorting to specify the cellular identities of the adipogenic and osteogenic lineages of the bone.
Thu Jun 01 00:00:00 EDT 2017
A CCR4 antagonist reverses the tumor-promoting microenvironment of renal cancer.
The Journal of clinical investigation
Berlato C,Khan MN,Schioppa T,Thompson R,Maniati E,Montfort A,Jangani M,Canosa M,Kulbe H,Hagemann UB,Duncan AR,Fletcher L,Wilkinson RW,Powles T,Quezada SA,Balkwill FR
Published figure using CD45 monoclonal antibody (Product # 12-0451-82) in Flow Cytometry
Wed Mar 01 00:00:00 EST 2017
PTEN drives Th17 cell differentiation by preventing IL-2 production.
The Journal of experimental medicine
Kim HS,Jang SW,Lee W,Kim K,Sohn H,Hwang SS,Lee GR
12-0451 was used in Flow cytometry/Cell sorting to show that PTEN plays a key role in Th17 cell differentiation by blocking IL-2 expression.
Mon Nov 06 00:00:00 EST 2017
Oncolytic Adenovirus and Tumor-Targeting Immune Modulatory Therapy Improve Autologous Cancer Vaccination.
Cancer research
Jiang H,Rivera-Molina Y,Gomez-Manzano C,Clise-Dwyer K,Bover L,Vence LM,Yuan Y,Lang FF,Toniatti C,Hossain MB,Fueyo J
Published figure using CD45 monoclonal antibody (Product # 12-0451-82) in Flow Cytometry
Sat Jul 15 00:00:00 EDT 2017
Virus-induced inflammasome activation is suppressed by prostaglandin D2/DP1 signaling.
Proceedings of the National Academy of Sciences of the United States of America
Vijay R,Fehr AR,Janowski AM,Athmer J,Wheeler DL,Grunewald M,Sompallae R,Kurup SP,Meyerholz DK,Sutterwala FS,Narumiya S,Perlman S
12-0451 was used in Flow cytometry/Cell sorting to study the role of Prostaglandin D2 signalling in optimal microglia/macrophage activation and interferon expression after infection with a neurotropic coronavirus.
Mon Jul 03 00:00:00 EDT 2017
Sigma-1 receptors control immune-driven peripheral opioid analgesia during inflammation in mice.
Proceedings of the National Academy of Sciences of the United States of America
Tejada MA,Montilla-García A,Cronin SJ,Cikes D,Sánchez-Fernández C,González-Cano R,Ruiz-Cantero MC,Penninger JM,Vela JM,Baeyens JM,Cobos EJ
Published figure using CD45 monoclonal antibody (Product # 12-0451-82) in Flow Cytometry
Tue Aug 01 00:00:00 EDT 2017
Obesity reversibly depletes the basal cell population and enhances mammary epithelial cell estrogen receptor alpha expression and progenitor activity.
Breast cancer research : BCR
Chamberlin T,D'Amato JV,Arendt LM
Wed Nov 29 00:00:00 EST 2017
Depletion of microglia exacerbates postischemic inflammation and brain injury.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism
Jin WN,Shi SX,Li Z,Li M,Wood K,Gonzales RJ,Liu Q
Published figure using CD45 monoclonal antibody (Product # 12-0451-82) in Flow Cytometry
Thu Jun 01 00:00:00 EDT 2017
An atypical role for the myeloid receptor Mincle in central nervous system injury.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism
Arumugam TV,Manzanero S,Furtado M,Biggins PJ,Hsieh YH,Gelderblom M,MacDonald KP,Salimova E,Li YI,Korn O,Dewar D,Macrae IM,Ashman RB,Tang SC,Rosenthal NA,Ruitenberg MJ,Magnus T,Wells CA
Published figure using CD45 monoclonal antibody (Product # 12-0451-82) in Flow Cytometry
Thu Jun 01 00:00:00 EDT 2017
Chemokine Receptor Ccr7 Restricts Fatal West Nile Virus Encephalitis.
Journal of virology
Bardina SV,Brown JA,Michlmayr D,Hoffman KW,Sum J,Pletnev AG,Lira SA,Lim JK
12-0451 was used in Flow cytometry/Cell sorting to point to Ccr7 as a critical host defense restriction factor limiting neuroinflammation during acute viral infection.
Mon May 15 00:00:00 EDT 2017
Role of Triggering Receptor Expressed on Myeloid Cell-1 Expression in Mammalian Target of Rapamycin Modulation of CD8+ T-cell Differentiation during the Immune Response to Invasive Pulmonary Aspergillosis.
Chinese medical journal
Cui N,Wang H,Su LX,Zhang JH,Long Y,Liu DW
Published figure using CD45 monoclonal antibody (Product # 12-0451-82) in Flow Cytometry
Sat May 20 00:00:00 EDT 2017
Cornea lymphatics drive the CD8+ T-cell response to herpes simplex virus-1.
Immunology and cell biology
Gurung HR,Carr MM,Carr DJ
Published figure using CD45 monoclonal antibody (Product # 12-0451-82) in Flow Cytometry
Sun Jan 01 00:00:00 EST 2017
Cytochrome P450 26A1 modulates natural killer cells in mouse early pregnancy.
Journal of cellular and molecular medicine
Meng CY,Li ZY,Fang WN,Song ZH,Yang DD,Li DD,Yang Y,Peng JP
Published figure using CD45 monoclonal antibody (Product # 12-0451-82) in Flow Cytometry
Sat Apr 01 00:00:00 EDT 2017
β3-Adrenergic Regulation of EPC Features Through Manipulation of the Bone Marrow MSC Niche.
Journal of cellular biochemistry
Vafaei R,Nassiri SM,Siavashi V
Published figure using CD45 monoclonal antibody (Product # 12-0451-82) in Flow Cytometry
Fri Dec 01 00:00:00 EST 2017
The common parasite Toxoplasma gondii induces prostatic inflammation and microglandular hyperplasia in a mouse model.
The Prostate
Colinot DL,Garbuz T,Bosland MC,Wang L,Rice SE,Sullivan WJ,Arrizabalaga G,Jerde TJ
Published figure using CD45 monoclonal antibody (Product # 12-0451-82) in Flow Cytometry
Sat Jul 01 00:00:00 EDT 2017
Estrogen protection against EAE modulates the microbiota and mucosal-associated regulatory cells.
Journal of neuroimmunology
Benedek G,Zhang J,Nguyen H,Kent G,Seifert HA,Davin S,Stauffer P,Vandenbark AA,Karstens L,Asquith M,Offner H
Fri Sep 15 00:00:00 EDT 2017
Fractional Laser Releases Tumor-Associated Antigens in Poorly Immunogenic Tumor and Induces Systemic Immunity.
Scientific reports
Kawakubo M,Cunningham TJ,Demehri S,Manstein D
12-0451 was used in Flow cytometry/Cell sorting to assess the utility of ablative fractional photothermolysis for treating oncological indications.
Fri Oct 06 00:00:00 EDT 2017
The PERK arm of the unfolded protein response regulates satellite cell-mediated skeletal muscle regeneration.
eLife
Xiong G,Hindi SM,Mann AK,Gallot YS,Bohnert KR,Cavener DR,Whittemore SR,Kumar A
Published figure using CD45 monoclonal antibody (Product # 12-0451-82) in Flow Cytometry
Thu Mar 23 00:00:00 EDT 2017
Flow cytometric single cell analysis reveals heterogeneity between adipose depots.
Adipocyte
Boumelhem BB,Assinder SJ,Bell-Anderson KS,Fraser ST
12-0451-82 was used in Flow cytometry/Cell sorting to report a system for analyzing live adipocytes from different adipose depots in the adult mouse.
Mon Apr 03 00:00:00 EDT 2017
IL-12 Influence mTOR to Modulate CD8+ T Cells Differentiation through T-bet and Eomesodermin in Response to Invasive Pulmonary Aspergillosis.
International journal of medical sciences
Wang H,Li J,Han Q,Yang F,Xiao Y,Xiao M,Xu Y,Su L,Cui N,Liu D
12-0451 was used in Flow cytometry/Cell sorting to investigate whether the mTOR signalling pathway regulates the proliferation and differentiation of CD8+ T cells in an invasive pulmonary aspergillosis mouse model.
Mon May 21 00:00:00 EDT 2018
microRNA-449a modulates medullary thymic epithelial cell differentiation.
Scientific reports
Chen P,Zhang H,Sun X,Hu Y,Jiang W,Liu Z,Liu S,Zhang X
Published figure using CD45 monoclonal antibody (Product # 12-0451-82) in Flow Cytometry
Tue Nov 21 00:00:00 EST 2017
Tristetraprolin expression by keratinocytes controls local and systemic inflammation.
JCI insight
Andrianne M,Assabban A,La C,Mogilenko D,Salle DS,Fleury S,Doumont G,Van Simaeys G,Nedospasov SA,Blackshear PJ,Dombrowicz D,Goriely S,Van Maele L
Published figure using CD45 monoclonal antibody (Product # 12-0451-82) in Flow Cytometry
Fri Jun 02 00:00:00 EDT 2017
Three-dimensional tumor cell growth stimulates autophagic flux and recapitulates chemotherapy resistance.
Cell death & disease
Bingel C,Koeneke E,Ridinger J,Bittmann A,Sill M,Peterziel H,Wrobel JK,Rettig I,Milde T,Fernekorn U,Weise F,Schober A,Witt O,Oehme I
12-0451-82 was used in Flow Cytometry to show that 3D growth within a bioreactor system modulates key hallmarks of cancer cells.
Thu Aug 24 00:00:00 EDT 2017
Single-cell profiling reveals GPCR heterogeneity and functional patterning during neuroinflammation.
JCI insight
Tischner D,Grimm M,Kaur H,Staudenraus D,Carvalho J,Looso M,Günther S,Wanke F,Moos S,Siller N,Breuer J,Schwab N,Zipp F,Waisman A,Kurschus FC,Offermanns S,Wettschureck N
12-0451 was used in Flow cytometry/Cell sorting to identify functionally distinct adaptive GPCR heterogeneity patternation in mice.
Thu Aug 03 00:00:00 EDT 2017
CCDC88B is required for pathogenesis of inflammatory bowel disease.
Nature communications
Fodil N,Moradin N,Leung V,Olivier JF,Radovanovic I,Jeyakumar T,Flores Molina M,McFarquhar A,Cayrol R,Bozec D,Shoukry NH,Kubo M,Dimitrieva J,Louis E,Theatre E,Dahan S,Momozawa Y,Georges M,Yeretssian G,Gros P
12-0451 was used in Immunofluorescence to suggest that CCDC88B has a critical function in colon inflammation and the pathogenesis of inflammatory bowel disease.
Fri Oct 13 00:00:00 EDT 2017
The Interleukin (IL)-1R1 pathway is a critical negative regulator of PyMT-mediated mammary tumorigenesis and pulmonary metastasis.
Oncoimmunology
Dagenais M,Dupaul-Chicoine J,Douglas T,Champagne C,Morizot A,Saleh M
Published figure using CD45 monoclonal antibody (Product # 12-0451-82) in Flow Cytometry
Tue Jan 12 00:00:00 EST 2021
Zoledronate suppressed angiogenesis and osteogenesis by inhibiting osteoclasts formation and secretion of PDGF-BB.
PloS one
Gao SY,Zheng GS,Wang L,Liang YJ,Zhang SE,Lao XM,Li K,Liao GQ
Published figure using CD45 monoclonal antibody (Product # 12-0451-82) in Flow Cytometry
Mon Sep 18 00:00:00 EDT 2017
Irgm1 coordinately regulates autoimmunity and host defense at select mucosal surfaces.
JCI insight
Azzam KM,Madenspacher JH,Cain DW,Lai L,Gowdy KM,Rai P,Janardhan K,Clayton N,Cunningham W,Jensen H,Patel PS,Kearney JF,Taylor GA,Fessler MB
Published figure using CD45 monoclonal antibody (Product # 12-0451-82) in Flow Cytometry
Thu Aug 17 00:00:00 EDT 2017
Cardiosphere-Derived Cells Require Endoglin for Paracrine-Mediated Angiogenesis.
Stem cell reports
Redgrave RE,Tual-Chalot S,Davison BJ,Singh E,Hall D,Amirrasouli MM,Gilchrist D,Medvinsky A,Arthur HM
Published figure using CD45 monoclonal antibody (Product # 12-0451-82) in Flow Cytometry
Tue May 09 00:00:00 EDT 2017
Heavy Chain-Hyaluronan/Pentraxin 3 from Amniotic Membrane Suppresses Inflammation and Scarring in Murine Lacrimal Gland and Conjunctiva of Chronic Graft-versus-Host Disease.
Scientific reports
Ogawa Y,He H,Mukai S,Imada T,Nakamura S,Su CW,Mahabole M,Tseng SC,Tsubota K
12-0451 was used in Western Blotting to help prove the concept that subcutaneous and subconjunctival injection of HC-HA/PTX3 is a novel approach to prevent dry eye disease caused by cGVHD.
Mon Feb 06 00:00:00 EST 2017
High-fat diet enhances stemness and tumorigenicity of intestinal progenitors.
Nature
Beyaz S,Mana MD,Roper J,Kedrin D,Saadatpour A,Hong SJ,Bauer-Rowe KE,Xifaras ME,Akkad A,Arias E,Pinello L,Katz Y,Shinagare S,Abu-Remaileh M,Mihaylova MM,Lamming DW,Dogum R,Guo G,Bell GW,Selig M,Nielsen GP,Gupta N,Ferrone CR,Deshpande V,Yuan GC,Orkin SH,Sabatini DM,Yilmaz ÖH
12-0451 was used in Flow cytometry/Cell sorting to demonstrate that a high-fat diet augments the numbers and proliferation of intestinal stem-cells.
Thu Mar 03 00:00:00 EST 2016
The Hippo Pathway Kinases LATS1/2 Suppress Cancer Immunity.
Cell
Moroishi T,Hayashi T,Pan WW,Fujita Y,Holt MV,Qin J,Carson DA,Guan KL
12-0451 was used in Immunohistochemistry-immunofluorescence to observe the role played by the Hippo pathway in suppressing anti-tumour immunity.
Thu Dec 01 00:00:00 EST 2016
Classical dendritic cells are required for dietary antigen-mediated induction of peripheral T(reg) cells and tolerance.
Nature immunology
Esterházy D,Loschko J,London M,Jove V,Oliveira TY,Mucida D
Published figure using CD45 monoclonal antibody (Product # 12-0451-82) in Flow Cytometry
Sun May 01 00:00:00 EDT 2016
Oligodendrocyte death results in immune-mediated CNS demyelination.
Nature neuroscience
Traka M,Podojil JR,McCarthy DP,Miller SD,Popko B
Published figure using CD45 monoclonal antibody (Product # 12-0451-82) in Flow Cytometry
Fri Jan 01 00:00:00 EST 2016
The breast tumor microenvironment alters the phenotype and function of natural killer cells.
Cellular & molecular immunology
Krneta T,Gillgrass A,Chew M,Ashkar AA
Published figure using CD45 monoclonal antibody (Product # 12-0451-82) in Flow Cytometry
Thu Sep 01 00:00:00 EDT 2016
Non-Cell-Autonomous Regulation of Prostate Epithelial Homeostasis by Androgen Receptor.
Molecular cell
Zhang B,Kwon OJ,Henry G,Malewska A,Wei X,Zhang L,Brinkley W,Zhang Y,Castro PD,Titus M,Chen R,Sayeeduddin M,Raj GV,Mauck R,Roehrborn C,Creighton CJ,Strand DW,Ittmann MM,Xin L
Published figure using CD45 monoclonal antibody (Product # 12-0451-82) in Flow Cytometry
Thu Sep 15 00:00:00 EDT 2016
Lymphatic Contribution to the Cellular Niche in Heterotopic Ossification.
Annals of surgery
Loder S,Agarwal S,Sorkin M,Breuler C,Li J,Peterson J,Gardenier J,Hsieh HH,Wang SC,Mehrara BJ,Levi B
Published figure using CD45 monoclonal antibody (Product # 12-0451-82) in Flow Cytometry
Thu Dec 01 00:00:00 EST 2016
An Effective Immuno-PET Imaging Method to Monitor CD8-Dependent Responses to Immunotherapy.
Cancer research
Tavaré R,Escuin-Ordinas H,Mok S,McCracken MN,Zettlitz KA,Salazar FB,Witte ON,Ribas A,Wu AM
12-0451 was used in Flow cytometry/Cell sorting to investigate anti-CD8 immuno-PET as a sensitive tool for tracking systemic and tumour-infiltrating CD8+ T cell expression in tumour immunotherapy models.
Fri Jan 01 00:00:00 EST 2016
Dysregulated YAP1/TAZ and TGF-β signaling mediate hepatocarcinogenesis in Mob1a/1b-deficient mice.
Proceedings of the National Academy of Sciences of the United States of America
Nishio M,Sugimachi K,Goto H,Wang J,Morikawa T,Miyachi Y,Takano Y,Hikasa H,Itoh T,Suzuki SO,Kurihara H,Aishima S,Leask A,Sasaki T,Nakano T,Nishina H,Nishikawa Y,Sekido Y,Nakao K,Shin-Ya K,Mimori K,Suzuki A
12-0451 was used in Immunofluorescence to study the molecular mechanisms underpinning the pathology of Mob1a/1b-deficient mice.
Tue Jan 05 00:00:00 EST 2016
Analysis of Bone-Cartilage-Stromal Progenitor Populations in Trauma Induced and Genetic Models of Heterotopic Ossification.
Stem cells (Dayton, Ohio)
Agarwal S,Loder SJ,Sorkin M,Li S,Shrestha S,Zhao B,Mishina Y,James AW,Levi B
Published figure using CD45 monoclonal antibody (Product # 12-0451-82) in Flow Cytometry
Wed Jun 01 00:00:00 EDT 2016
Resident T Cells Are Unable To Control Herpes Simplex Virus-1 Activity in the Brain Ependymal Region during Latency.
Journal of immunology (Baltimore, Md. : 1950)
Menendez CM,Jinkins JK,Carr DJ
Published figure using CD45 monoclonal antibody (Product # 12-0451-82) in Flow Cytometry
Mon Aug 15 00:00:00 EDT 2016
Protein Translation Activity: A New Measure of Host Immune Cell Activation.
Journal of immunology (Baltimore, Md. : 1950)
Seedhom MO,Hickman HD,Wei J,David A,Yewdell JW
12-0451 was used in Flow cytometry/Cell sorting to describe the in vivo ribopuromycylation method.
Mon Aug 15 00:00:00 EDT 2016
ECM-Dependence of Endothelial Progenitor Cell Features.
Journal of cellular biochemistry
Siavashi V,Nassiri SM,Rahbarghazi R,Vafaei R,Sariri R
Published figure using CD45 monoclonal antibody (Product # 12-0451-82) in Flow Cytometry
Mon Aug 01 00:00:00 EDT 2016
Effects of nerve growth factor and basic fibroblast growth factor dual gene modification on rat bone marrow mesenchymal stem cell differentiation into neuron-like cells in vitro.
Molecular medicine reports
Hu Y,Zhang Y,Tian K,Xun C,Wang S,Lv D
Published figure using CD45 monoclonal antibody (Product # 12-0451-82) in Flow Cytometry
Fri Jan 01 00:00:00 EST 2016
A flow cytometric approach to analyzing mature and progenitor endothelial cells following traumatic brain injury.
Journal of neuroscience methods
Assis-Nascimento P,Umland O,Cepero ML,Liebl DJ
Published figure using CD45 monoclonal antibody (Product # 12-0451-82) in Flow Cytometry
Fri Apr 01 00:00:00 EDT 2016
A cell-autonomous tumour suppressor role of RAF1 in hepatocarcinogenesis.
Nature communications
Jeric I,Maurer G,Cavallo AL,Raguz J,Desideri E,Tarkowski B,Parrini M,Fischer I,Zatloukal K,Baccarini M
Published figure using CD45 monoclonal antibody (Product # 12-0451-82) in Flow Cytometry
Wed Dec 21 00:00:00 EST 2016
Stromal senescence establishes an immunosuppressive microenvironment that drives tumorigenesis.
Nature communications
Ruhland MK,Loza AJ,Capietto AH,Luo X,Knolhoff BL,Flanagan KC,Belt BA,Alspach E,Leahy K,Luo J,Schaffer A,Edwards JR,Longmore G,Faccio R,DeNardo DG,Stewart SA
Published figure using CD45 monoclonal antibody (Product # 12-0451-82) in Flow Cytometry
Wed Jun 08 00:00:00 EDT 2016
Targeting VEGF-A in myeloid cells enhances natural killer cell responses to chemotherapy and ameliorates cachexia.
Nature communications
Klose R,Krzywinska E,Castells M,Gotthardt D,Putz EM,Kantari-Mimoun C,Chikdene N,Meinecke AK,Schrödter K,Helfrich I,Fandrey J,Sexl V,Stockmann C
Published figure using CD45 monoclonal antibody (Product # 12-0451-82) in Flow Cytometry
Fri Aug 19 00:00:00 EDT 2016
Protein Kinase D2 Protects against Acute Colitis Induced by Dextran Sulfate Sodium in Mice.
Scientific reports
Xiong J,Zhou MF,Wang YD,Chen LP,Xu WF,Wang YD,Deng F,Liu SD
Published figure using CD45 monoclonal antibody (Product # 12-0451-82) in Flow Cytometry
Fri Sep 23 00:00:00 EDT 2016
MHC-compatible bone marrow stromal/stem cells trigger fibrosis by activating host T cells in a scleroderma mouse model.
eLife
Ogawa Y,Morikawa S,Okano H,Mabuchi Y,Suzuki S,Yaguchi T,Sato Y,Mukai S,Yaguchi S,Inaba T,Okamoto S,Kawakami Y,Tsubota K,Matsuzaki Y,Shimmura S
12-0451 was used in Flow cytometry/Cell sorting to investigate the fibrosis in a scleroderma mouse model which is triggered by antigen mismatched bone marrow stromal/stem cells.
Tue Jan 26 00:00:00 EST 2016
Reprogramming mouse fibroblasts into engraftable myeloerythroid and lymphoid progenitors.
Nature communications
Cheng H,Ang HY,A El Farran C,Li P,Fang HT,Liu TM,Kong SL,Chin ML,Ling WY,Lim EK,Li H,Huber T,Loh KM,Loh YH,Lim B
12-0451 was used in Flow cytometry/Cell sorting to demonstrate how it is possible to reprogram mouse embryonic fibroblasts into engraftable blood progenitors.
Mon Nov 21 00:00:00 EST 2016
Preparation of Single Cell Suspensions from Mouse Aorta.
Bio-protocol
Hu D,Yin C,Mohanta SK,Weber C,Habenicht AJ
Published figure using CD45 monoclonal antibody (Product # 12-0451-82) in Flow Cytometry
Sun Jun 05 00:00:00 EDT 2016
NFAT restricts osteochondroma formation from entheseal progenitors.
JCI insight
Ge X,Tsang K,He L,Garcia RA,Ermann J,Mizoguchi F,Zhang M,Zhou B,Zhou B,Aliprantis AO
12-0451 was used in Flow cytometry/Cell sorting to demonstrate that nuclear factor of activated T cells c1 and c2 suppress osteochondromagenesis through individual and combinatorial mechanisms in mice.
Fri Apr 01 00:00:00 EDT 2016
Irradiation of necrotic cancer cells, employed for pulsing dendritic cells (DCs), potentiates DC vaccine-induced antitumor immunity against high-grade glioma.
Oncoimmunology
Vandenberk L,Garg AD,Verschuere T,Koks C,Belmans J,Beullens M,Agostinis P,De Vleeschouwer S,Van Gool SW
Published figure using CD45 monoclonal antibody (Product # 12-0451-82) in Flow Cytometry
Mon Feb 01 00:00:00 EST 2016
Diet-dependent, microbiota-independent regulation of IL-10-producing lamina propria macrophages in the small intestine.
Scientific reports
Ochi T,Feng Y,Kitamoto S,Nagao-Kitamoto H,Kuffa P,Atarashi K,Honda K,Teitelbaum DH,Kamada N
Published figure using CD45 monoclonal antibody (Product # 12-0451-82) in Flow Cytometry
Wed Jun 15 00:00:00 EDT 2016
LTβR controls thymic portal endothelial cells for haematopoietic progenitor cell homing and T-cell regeneration.
Nature communications
Shi Y,Wu W,Chai Q,Li Q,Hou Y,Xia H,Ren B,Xu H,Guo X,Jin C,Lv M,Wang Z,Fu YX,Zhu M
Published figure using CD45 monoclonal antibody (Product # 12-0451-82) in Flow Cytometry
Fri Aug 05 00:00:00 EDT 2016
KLF4-dependent phenotypic modulation of smooth muscle cells has a key role in atherosclerotic plaque pathogenesis.
Nature medicine
Shankman LS,Gomez D,Cherepanova OA,Salmon M,Alencar GF,Haskins RM,Swiatlowska P,Newman AA,Greene ES,Straub AC,Isakson B,Randolph GJ,Owens GK
12-0451 was used in Flow cytometry/Cell sorting to show how KLF4-dependent phenotypic modulation of smooth muscle cells has a key role in atherosclerotic plaque pathogenesis.
Mon Jun 01 00:00:00 EDT 2015
Host microbiota constantly control maturation and function of microglia in the CNS.
Nature neuroscience
Erny D,Hrabě de Angelis AL,Jaitin D,Wieghofer P,Staszewski O,David E,Keren-Shaul H,Mahlakoiv T,Jakobshagen K,Buch T,Schwierzeck V,Utermöhlen O,Chun E,Garrett WS,McCoy KD,Diefenbach A,Staeheli P,Stecher B,Amit I,Prinz M
Published figure using CD45 monoclonal antibody (Product # 12-0451-82) in Flow Cytometry
Wed Jul 01 00:00:00 EDT 2015
Vascular niche promotes hematopoietic multipotent progenitor formation from pluripotent stem cells.
The Journal of clinical investigation
Gori JL,Butler JM,Chan YY,Chandrasekaran D,Poulos MG,Ginsberg M,Nolan DJ,Elemento O,Wood BL,Adair JE,Rafii S,Kiem HP
Published figure using CD45 monoclonal antibody (Product # 12-0451-82) in Flow Cytometry
Mon Mar 02 00:00:00 EST 2015
Phagocytosis-dependent activation of a TLR9-BTK-calcineurin-NFAT pathway co-ordinates innate immunity to Aspergillus fumigatus.
EMBO molecular medicine
Herbst S,Shah A,Mazon Moya M,Marzola V,Jensen B,Reed A,Birrell MA,Saijo S,Mostowy S,Shaunak S,Armstrong-James D
Published figure using CD45 monoclonal antibody (Product # 12-0451-82) in Flow Cytometry
Sun Mar 01 00:00:00 EST 2015
Tracking and Functional Characterization of Epithelial-Mesenchymal Transition and Mesenchymal Tumor Cells during Prostate Cancer Metastasis.
Cancer research
Ruscetti M,Quach B,Dadashian EL,Mulholland DJ,Wu H
Published figure using CD45 monoclonal antibody (Product # 12-0451-82) in Flow Cytometry
Wed Jul 01 00:00:00 EDT 2015
Atypical chemokine receptor 1 deficiency reduces atherogenesis in ApoE-knockout mice.
Cardiovascular research
Wan W,Liu Q,Lionakis MS,Marino AP,Anderson SA,Swamydas M,Murphy PM
Published figure using CD45 monoclonal antibody (Product # 12-0451-82) in Flow Cytometry
Mon Jun 01 00:00:00 EDT 2015
Differential Roles of Chemokines CCL2 and CCL7 in Monocytosis and Leukocyte Migration during West Nile Virus Infection.
Journal of immunology (Baltimore, Md. : 1950)
Bardina SV,Michlmayr D,Hoffman KW,Obara CJ,Sum J,Charo IF,Lu W,Pletnev AG,Lim JK
12-0451 was used in Flow cytometry/Cell sorting to investigate the molecular mechanisms of inflammatory monocyte migration in West Nile Virus encephalitis, showing differential roles of CCL2 and CCL7 in monocytosis and leukocyte migration.
Sun Nov 01 00:00:00 EDT 2015
Does FACS perturb gene expression?
Cytometry. Part A : the journal of the International Society for Analytical Cytology
Richardson GM,Lannigan J,Macara IG
12-0451 was used in Flow cytometry/Cell sorting to examine the effects of fluorescence activated cell sorting separation on short-term transcriptional profiles.
Sun Feb 01 00:00:00 EST 2015
Conditional immortalization of primary adipocyte precursor cells.
Adipocyte
Church C,Brown M,Rodeheffer MS
Published figure using CD45 monoclonal antibody (Product # 12-0451-82) in Flow Cytometry
Mon Aug 10 00:00:00 EDT 2015
Nonadherent culture method downregulates stem cell antigen-1 expression in mouse bone marrow mesenchymal stem cells.
Experimental and therapeutic medicine
Deng B,Deng W,Xiao P,Zeng K,Zhang S,Zhang H,Deng DY,Yang Y
Published figure using CD45 monoclonal antibody (Product # 12-0451-82) in Flow Cytometry
Wed Jul 01 00:00:00 EDT 2015
High-level Gpr56 expression is dispensable for the maintenance and function of hematopoietic stem and progenitor cells in mice.
Stem cell research
Rao TN,Marks-Bluth J,Sullivan J,Gupta MK,Chandrakanthan V,Fitch SR,Ottersbach K,Jang YC,Piao X,Kulkarni RN,Serwold T,Pimanda JE,Wagers AJ
12-0451 was used in Flow cytometry/Cell sorting to indicate that high-level expression of GPR56 by primitive HSPCs is largely dispensable for steady-state and regenerative hematopoiesis.
Fri May 01 00:00:00 EDT 2015
Favorable alteration of tumor microenvironment by immunomodulatory cytokines for efficient T-cell therapy in solid tumors.
PloS one
Tähtinen S,Kaikkonen S,Merisalo-Soikkeli M,Grönberg-Vähä-Koskela S,Kanerva A,Parviainen S,Vähä-Koskela M,Hemminki A
Published figure using CD45 monoclonal antibody (Product # 12-0451-82) in Flow Cytometry
Thu Apr 28 00:00:00 EDT 2016
Distinct in vitro properties of embryonic and extraembryonic fibroblast-like cells are reflected in their in vivo behavior following grafting in the adult mouse brain.
Cell transplantation
Costa R,Bergwerf I,Santermans E,De Vocht N,Praet J,Daans J,Le Blon D,Hoornaert C,Reekmans K,Hens N,Goossens H,Berneman Z,Parolini O,Alviano F,Ponsaerts P
Published figure using CD45 monoclonal antibody (Product # 12-0451-82) in Flow Cytometry
Mon Nov 16 00:00:00 EST 2015
The Nuclear Orphan Receptor NR2F6 Is a Central Checkpoint for Cancer Immune Surveillance.
Cell reports
Hermann-Kleiter N,Klepsch V,Wallner S,Siegmund K,Klepsch S,Tuzlak S,Villunger A,Kaminski S,Pfeifhofer-Obermair C,Gruber T,Wolf D,Baier G
Published figure using CD45 monoclonal antibody (Product # 12-0451-82) in Flow Cytometry
Tue Sep 29 00:00:00 EDT 2015
Glioma-associated microglia/macrophages display an expression profile different from M1 and M2 polarization and highly express Gpnmb and Spp1.
PloS one
Szulzewsky F,Pelz A,Feng X,Synowitz M,Markovic D,Langmann T,Holtman IR,Wang X,Eggen BJ,Boddeke HW,Hambardzumyan D,Wolf SA,Kettenmann H
Published figure using CD45 monoclonal antibody (Product # 12-0451-82) in Flow Cytometry
Tue Jan 12 00:00:00 EST 2016
TH2 cells and their cytokines regulate formation and function of lymphatic vessels.
Nature communications
Shin K,Kataru RP,Park HJ,Kwon BI,Kim TW,Hong YK,Lee SH
12-0451 was used in Flow cytometry/Cell sorting to demonstrate an anti-lymphangiogenic function of Th2 cells and their cytokines IL-4 and IL-13, and show that blockade of these cytokines improves lymphatic function in an asthma model.
Wed Feb 04 00:00:00 EST 2015
Targeted Gene Correction in Osteopetrotic-Induced Pluripotent Stem Cells for the Generation of Functional Osteoclasts.
Stem cell reports
Neri T,Muggeo S,Paulis M,Caldana ME,Crisafulli L,Strina D,Focarelli ML,Faggioli F,Recordati C,Scaramuzza S,Scanziani E,Mantero S,Buracchi C,Sobacchi C,Lombardo A,Naldini L,Vezzoni P,Villa A,Ficara F
Published figure using CD45 monoclonal antibody (Product # 12-0451-82) in Flow Cytometry
Tue Oct 13 00:00:00 EDT 2015
The Transcriptional Repressor ZNF503/Zeppo2 Promotes Mammary Epithelial Cell Proliferation and Enhances Cell Invasion.
The Journal of biological chemistry
Shahi P,Slorach EM,Wang CY,Chou J,Lu A,Ruderisch A,Werb Z
12-0451 was used in Flow cytometry/Cell sorting to demonstrate the significant role of Zpo2 in mammary gland homeostasis, and that Zpo2 deregulation may promote breast cancer development.
Fri Feb 06 00:00:00 EST 2015
Cardiac telocytes and fibroblasts in primary culture: different morphologies and immunophenotypes.
PloS one
Bei Y,Zhou Q,Fu S,Lv D,Chen P,Chen Y,Wang F,Xiao J
Published figure using CD45 monoclonal antibody (Product # 12-0451-82) in Flow Cytometry
Wed Nov 11 00:00:00 EST 2015
Galectin-3 deficiency exacerbates hyperglycemia and the endothelial response to diabetes.
Cardiovascular diabetology
Darrow AL,Shohet RV
Published figure using CD45 monoclonal antibody (Product # 12-0451-82) in Flow Cytometry
Sat Jun 06 00:00:00 EDT 2015
Endothelial Gata5 transcription factor regulates blood pressure.
Nature communications
Messaoudi S,He Y,Gutsol A,Wight A,Hébert RL,Vilmundarson RO,Makrigiannis AP,Chalmers J,Hamet P,Tremblay J,McPherson R,Stewart AFR,Touyz RM,Nemer M
Published figure using CD45 monoclonal antibody (Product # 12-0451-82) in Flow Cytometry
Mon Nov 30 00:00:00 EST 2015
Intronic regulation of Aire expression by Jmjd6 for self-tolerance induction in the thymus.
Nature communications
Yanagihara T,Sanematsu F,Sato T,Uruno T,Duan X,Tomino T,Harada Y,Watanabe M,Wang Y,Tanaka Y,Nakanishi Y,Suyama M,Yoshinori F
12-0451 was used in Flow cytometry/Cell sorting to study the regulation of Aire expression in medullary thymic epithelial cells.
Wed Nov 04 00:00:00 EST 2015
Reprogramming human endothelial cells to haematopoietic cells requires vascular induction.
Nature
Sandler VM,Lis R,Liu Y,Kedem A,James D,Elemento O,Butler JM,Scandura JM,Rafii S
Published figure using CD45 monoclonal antibody (Product # 12-0451-82) in Flow Cytometry
Thu Jul 17 00:00:00 EDT 2014
Sex disparity in colonic adenomagenesis involves promotion by male hormones, not protection by female hormones.
Proceedings of the National Academy of Sciences of the United States of America
Amos-Landgraf JM,Heijmans J,Wielenga MC,Dunkin E,Krentz KJ,Clipson L,Ederveen AG,Groothuis PG,Mosselman S,Muncan V,Hommes DW,Shedlovsky A,Dove WF,van den Brink GR
12-0451 was used in Flow cytometry/Cell sorting to suggest that indirect tumour-promoting effects of testosterone likely explain the disparity between the sexes in the development of colonic adenomas.
Tue Nov 18 00:00:00 EST 2014
Cell-autonomous heparanase modulates self-renewal and migration in bone marrow-derived mesenchymal stem cells.
Journal of biomedical science
Cheng CC,Lee YH,Lin SP,Huangfu WC,Liu IH
12-0451 was used in Flow cytometry/Cell sorting to inhibit the enzymatic activity of cell-autonomous HPSE1 in BM-MSCs to clarify the physiological role of HPSE1 in BM-MSCs.
Thu Mar 13 00:00:00 EDT 2014
Astrocytic transforming growth factor-beta signaling reduces subacute neuroinflammation after stroke in mice.
Glia
Cekanaviciute E,Fathali N,Doyle KP,Williams AM,Han J,Buckwalter MS
Published figure using CD45 monoclonal antibody (Product # 12-0451-82) in Flow Cytometry
Fri Aug 01 00:00:00 EDT 2014
Age-dependent enterocyte invasion and microcolony formation by Salmonella.
PLoS pathogens
Zhang K,Dupont A,Torow N,Gohde F,Leschner S,Lienenklaus S,Weiss S,Brinkmann MM,Kühnel M,Hensel M,Fulde M,Hornef MW
12-0451 was used in Flow cytometry/Cell sorting to provide important insight in the early steps of Salmonella infection in vivo.
Mon Sep 01 00:00:00 EDT 2014
Bacterial superantigens promote acute nasopharyngeal infection by Streptococcus pyogenes in a human MHC Class II-dependent manner.
PLoS pathogens
Kasper KJ,Zeppa JJ,Wakabayashi AT,Xu SX,Mazzuca DM,Welch I,Baroja ML,Kotb M,Cairns E,Cleary PP,Haeryfar SM,McCormick JK
12-0451 was used in Flow cytometry/Cell sorting to study how secreted superantigens contribute to the fitness and evolution of S. pyogenes.
Thu May 01 00:00:00 EDT 2014
Targeted GAS6 delivery to the CNS protects axons from damage during experimental autoimmune encephalomyelitis.
The Journal of neuroscience : the official journal of the Society for Neuroscience
Gruber RC,Ray AK,Johndrow CT,Guzik H,Burek D,de Frutos PG,Shafit-Zagardo B
12-0451 was used in Flow cytometry/Cell sorting to test whether intracerebroventricular delivery of growth arrest-specific protein 6 during EAE in mice improves the clinical course of disease.
Wed Dec 03 00:00:00 EST 2014
Distinct spatial distribution of microglia and macrophages following mesenchymal stem cell implantation in mouse brain.
Immunology and cell biology
Le Blon D,Hoornaert C,Daans J,Santermans E,Hens N,Goossens H,Berneman Z,Ponsaerts P
12-0451 was used in Flow cytometry/Cell sorting to characterise the distribution of microglia and macrophages in the mouse brain following mesenchymal stem cell implantation, showing that resident immune cells surround the graft site while peripheral immune cells invade the graft.
Mon Sep 01 00:00:00 EDT 2014
Tracking the elusive fibrocyte: identification and characterization of collagen-producing hematopoietic lineage cells during murine wound healing.
Stem cells (Dayton, Ohio)
Suga H,Rennert RC,Rodrigues M,Sorkin M,Glotzbach JP,Januszyk M,Fujiwara T,Longaker MT,Gurtner GC
Published figure using CD45 monoclonal antibody (Product # 12-0451-82) in Flow Cytometry
Thu May 01 00:00:00 EDT 2014
Bone marrow mesenchymal stem cells provide an antibiotic-protective niche for persistent viable Mycobacterium tuberculosis that survive antibiotic treatment.
The American journal of pathology
Beamer G,Major S,Das B,Campos-Neto A
Published figure using CD45 monoclonal antibody (Product # 12-0451-82) in Flow Cytometry
Mon Dec 01 00:00:00 EST 2014
Sox17-mediated maintenance of fetal intra-aortic hematopoietic cell clusters.
Molecular and cellular biology
Nobuhisa I,Osawa M,Uemura M,Kishikawa Y,Anani M,Harada K,Takagi H,Saito K,Kanai-Azuma M,Kanai Y,Iwama A,Taga T
12-0451 was used in Flow cytometry/Cell sorting to investigate how cells in intra-aortic clusters maintain their HSC phenotype, showing that they are maintained by Sox17.
Sun Jun 01 00:00:00 EDT 2014
Identification of hematopoietic-specific regulatory elements from the CD45 gene and use for lentiviral tracking of transplanted cells.
Experimental hematology
Duong KL,Das S,Yu S,Barr JY,Jena S,Kim E,Zavazava N,Colgan JD,Xue HH,Levasseur DN
Published figure using CD45 monoclonal antibody (Product # 12-0451-82) in Flow Cytometry
Mon Sep 01 00:00:00 EDT 2014
Dual modulation of the mitochondrial permeability transition pore and redox signaling synergistically promotes cardiomyocyte differentiation from pluripotent stem cells.
Journal of the American Heart Association
Cho SW,Park JS,Heo HJ,Park SW,Song S,Kim I,Han YM,Yamashita JK,Youm JB,Han J,Koh GY
12-0451 was used in Flow cytometry/Cell sorting to show that mPTP inhibition by CsA alters mitochondrial oxidative metabolism and redox signaling.
Thu Mar 13 00:00:00 EDT 2014
Dual modulation of the mitochondrial permeability transition pore and redox signaling synergistically promotes cardiomyocyte differentiation from pluripotent stem cells.
Journal of the American Heart Association
Cho SW,Park JS,Heo HJ,Park SW,Song S,Kim I,Han YM,Yamashita JK,Youm JB,Han J,Koh GY
12-0451 was used in Flow cytometry/Cell sorting to show that mPTP inhibition by CsA alters mitochondrial oxidative metabolism and redox signaling.
Thu Mar 13 00:00:00 EDT 2014
A new animal model of spontaneous autoimmune peripheral polyneuropathy: implications for Guillain-Barré syndrome.
Acta neuropathologica communications
Yang M,Rainone A,Shi XQ,Fournier S,Zhang J
Published figure using CD45 monoclonal antibody (Product # 12-0451-82) in Flow Cytometry
Wed Jan 08 00:00:00 EST 2014
Histological characterization and quantification of cellular events following neural and fibroblast(-like) stem cell grafting in healthy and demyelinated CNS tissue.
Methods in molecular biology (Clifton, N.J.)
Praet J,Santermans E,Reekmans K,de Vocht N,Le Blon D,Hoornaert C,Daans J,Goossens H,Berneman Z,Hens N,Van der Linden A,Ponsaerts P
12-0451-82 was used in Flow cytometry/Cell sorting to provide protocols to isolate eGFP(+) neural and fibroblast (-like) stem cells from embryonic mouse tissue, determine cell viability, and induce reproducible demyelination in the CNS of mice by means of cuprizone administration.
Fri May 22 00:00:00 EDT 2015
Amniotic fluid stem cells prevent follicle atresia and rescue fertility of mice with premature ovarian failure induced by chemotherapy.
PloS one
Xiao GY,Liu IH,Cheng CC,Chang CC,Lee YH,Cheng WT,Wu SC
Published figure using CD45 monoclonal antibody (Product # 12-0451-82) in Flow Cytometry
Thu May 28 00:00:00 EDT 2015
Identification of novel thymic epithelial cell subsets whose differentiation is regulated by RANKL and Traf6.
PloS one
Danzl NM,Jeong S,Choi Y,Alexandropoulos K
12-0451 was used in Immunocytochemistry to examine the developmental stages of thymic epithelial cells, identifying novel thymic epithelial cell subsets whose differentiation is regulated by RANKL and Traf6.
Wed Oct 29 00:00:00 EDT 2014
Activation of NLRP3 inflammasome by crystalline structures via cell surface contact.
Scientific reports
Hari A,Zhang Y,Tu Z,Detampel P,Stenner M,Ganguly A,Shi Y
Published figure using CD45 monoclonal antibody (Product # 12-0451-82) in Flow Cytometry
Tue Dec 02 00:00:00 EST 2014
The nucleotide-binding leucine-rich repeat (NLR) family member NLRX1 mediates protection against experimental autoimmune encephalomyelitis and represses macrophage/microglia-induced inflammation.
The Journal of biological chemistry
Eitas TK,Chou WC,Wen H,Gris D,Robbins GR,Brickey J,Oyama Y,Ting JP
Published figure using CD45 monoclonal antibody (Product # 12-0451-82) in Flow Cytometry
Fri Feb 14 00:00:00 EST 2014
γδT cells are prevalent in the proximal aorta and drive nascent atherosclerotic lesion progression and neutrophilia in hypercholesterolemic mice.
PloS one
Vu DM,Tai A,Tatro JB,Karas RH,Huber BT,Beasley D
12-0451 was used in Flow cytometry/Cell sorting to reveal a pathogenic role of γδT cells in early atherogenesis in ApoE KO mice, by mechanisms likely to involve their IL-17 production and induction of neutrophilia.
Tue Jun 16 00:00:00 EDT 2015
Distinct fibroblast lineages determine dermal architecture in skin development and repair.
Nature
Driskell RR,Lichtenberger BM,Hoste E,Kretzschmar K,Simons BD,Charalambous M,Ferron SR,Herault Y,Pavlovic G,Ferguson-Smith AC,Watt FM
12-0451 was used in Immunohistochemistry to explain why wounding is linked to formation of ECM-rich scar tissue that lacks hair follicles.
Thu Dec 12 00:00:00 EST 2013
GATA3 suppresses metastasis and modulates the tumour microenvironment by regulating microRNA-29b expression.
Nature cell biology
Chou J,Lin JH,Brenot A,Kim JW,Provot S,Werb Z
12-0451 was used in Flow cytometry/Cell sorting to study how the GATA3-miR-29b axis regulates the tumour microenvironment, and inhibits metastasis to open up possibilities for therapeutic intervention in breast cancer.
Fri Feb 01 00:00:00 EST 2013
Medullary thymic epithelial cell depletion leads to autoimmune hepatitis.
The Journal of clinical investigation
Bonito AJ,Aloman C,Fiel MI,Danzl NM,Cha S,Weinstein EG,Jeong S,Choi Y,Walsh MC,Alexandropoulos K
12-0451 was used in Flow cytometry/Cell sorting to investigate the role of TRAF6 and medullary thymic epithelial cells (mETCs) in autoimmunity, showing that mETC depletion leads to autoimmune hepatitis.
Thu Aug 01 00:00:00 EDT 2013
PDGFRα and CD51 mark human nestin+ sphere-forming mesenchymal stem cells capable of hematopoietic progenitor cell expansion.
The Journal of experimental medicine
Pinho S,Lacombe J,Hanoun M,Mizoguchi T,Bruns I,Kunisaki Y,Frenette PS
12-0451 was used in Immunofluorescence to evaluate putative cell surface mesenchymal stem cell markers to identify Nestin+ cells in the mouse and human bone marrow.
Mon Jul 01 00:00:00 EDT 2013
Genetic deletion of chemokine receptor Ccr7 exacerbates atherogenesis in ApoE-deficient mice.
Cardiovascular research
Wan W,Lionakis MS,Liu Q,Roffê E,Murphy PM
12-0451 was used in Flow cytometry/Cell sorting to study exacerbation of atherogenesis with genetic deletion of chemokine receptor Ccr7 in ApoE-deficient mice.
Fri Mar 01 00:00:00 EST 2013
Wt1-expressing progenitors contribute to multiple tissues in the developing lung.
American journal of physiology. Lung cellular and molecular physiology
Cano E,Carmona R,Muñoz-Chápuli R
12-0451 was used in Immunofluorescence to report a novel role for embryonic mesothelium-derived cells in lung morphogenesis.
Thu Aug 15 00:00:00 EDT 2013
Ganciclovir prophylaxis improves late murine cytomegalovirus-induced renal allograft damage.
Transplantation
Shimamura M,Seleme MC,Guo L,Saunders U,Schoeb TR,George JF,Britt WJ
12-0451 was used in Flow cytometry/Cell sorting to examine the lasting effect of Ganciclovir treatment on renal allografts after the discontinuation of prophylaxis.
Tue Jan 15 00:00:00 EST 2013
Proximal tubule PPARα attenuates renal fibrosis and inflammation caused by unilateral ureteral obstruction.
American journal of physiology. Renal physiology
Li S,Mariappan N,Megyesi J,Shank B,Kannan K,Theus S,Price PM,Duffield JS,Portilla D
12-0451 was used in Flow cytometry/Cell sorting to study how proximal tubule PPARα attenuates renal fibrosis and inflammation caused by unilateral ureteral obstruction.
Sun Sep 01 00:00:00 EDT 2013
Gli1 deletion prevents Helicobacter-induced gastric metaplasia and expansion of myeloid cell subsets.
PloS one
El-Zaatari M,Kao JY,Tessier A,Bai L,Hayes MM,Fontaine C,Eaton KA,Merchant JL
Published figure using CD45 monoclonal antibody (Product # 12-0451-82) in Flow Cytometry
Tue Sep 10 00:00:00 EDT 2013
Gli1 deletion prevents Helicobacter-induced gastric metaplasia and expansion of myeloid cell subsets.
PloS one
El-Zaatari M,Kao JY,Tessier A,Bai L,Hayes MM,Fontaine C,Eaton KA,Merchant JL
Published figure using CD45 monoclonal antibody (Product # 12-0451-82) in Flow Cytometry
Tue Sep 10 00:00:00 EDT 2013
mTORC1 in the Paneth cell niche couples intestinal stem-cell function to calorie intake.
Nature
Yilmaz ÖH,Katajisto P,Lamming DW,Gültekin Y,Bauer-Rowe KE,Sengupta S,Birsoy K,Dursun A,Yilmaz VO,Selig M,Nielsen GP,Mino-Kenudson M,Zukerberg LR,Bhan AK,Deshpande V,Sabatini DM
12-0451 was used in Flow cytometry/Cell sorting to explore how Paneth cells augment stem-cell function in response to calorie restriction.
Thu Jun 28 00:00:00 EDT 2012
Microparticles bearing encephalitogenic peptides induce T-cell tolerance and ameliorate experimental autoimmune encephalomyelitis.
Nature biotechnology
Getts DR,Martin AJ,McCarthy DP,Terry RL,Hunter ZN,Yap WT,Getts MT,Pleiss M,Luo X,King NJ,Shea LD,Miller SD
12-0451 was used in Flow cytometry/Cell sorting to highlight the potential for using microparticles to target natural apoptotic clearance pathways to inactivate pathogenic T cells in autoimmunity.
Sat Dec 01 00:00:00 EST 2012
Tumorigenic cells are common in mouse MPNSTs but their frequency depends upon tumor genotype and assay conditions.
Cancer cell
Buchstaller J,McKeever PE,Morrison SJ
Published figure using CD45 monoclonal antibody (Product # 12-0451-82) in Flow Cytometry
Tue Feb 14 00:00:00 EST 2012
Etv2 is expressed in the yolk sac hematopoietic and endothelial progenitors and regulates Lmo2 gene expression.
Stem cells (Dayton, Ohio)
Koyano-Nakagawa N,Kweon J,Iacovino M,Shi X,Rasmussen TL,Borges L,Zirbes KM,Li T,Perlingeiro RC,Kyba M,Garry DJ
Published figure using CD45 monoclonal antibody (Product # 12-0451-82) in Flow Cytometry
Wed Aug 01 00:00:00 EDT 2012
A model of GAG/MIP-2/CXCR2 interfaces and its functional effects.
Biochemistry
Rajasekaran D,Keeler C,Syed MA,Jones MC,Harrison JK,Wu D,Bhandari V,Hodsdon ME,Lolis EJ
Published figure using CD45 monoclonal antibody (Product # 12-0451-82) in Flow Cytometry
Tue Jul 17 00:00:00 EDT 2012
Cell type-associated differences in migration, survival, and immunogenicity following grafting in CNS tissue.
Cell transplantation
Praet J,Reekmans K,Lin D,De Vocht N,Bergwerf I,Tambuyzer B,Daans J,Hens N,Goossens H,Pauwels P,Berneman Z,Van der Linden A,Ponsaerts P
Published figure using CD45 monoclonal antibody (Product # 12-0451-82) in Flow Cytometry
Fri Dec 06 00:00:00 EST 2013
Cell type-associated differences in migration, survival, and immunogenicity following grafting in CNS tissue.
Cell transplantation
Praet J,Reekmans K,Lin D,De Vocht N,Bergwerf I,Tambuyzer B,Daans J,Hens N,Goossens H,Pauwels P,Berneman Z,Van der Linden A,Ponsaerts P
Published figure using CD45 monoclonal antibody (Product # 12-0451-82) in Flow Cytometry
Fri Dec 06 00:00:00 EST 2013
Oncogenic Kras expression in postmitotic neurons leads to S100A8-S100A9 protein overexpression and gliosis.
The Journal of biological chemistry
Ryu MJ,Liu Y,Zhong X,Du J,Peterson N,Kong G,Li H,Wang J,Salamat S,Chang Q,Zhang J
12-0451 was used in Flow cytometry/Cell sorting to determine how Ras signalling in neurones promotes gliosis and astrocytoma formation in a cell nonautonomous manner.
Fri Jun 29 00:00:00 EDT 2012
Stromal vascular fraction from adipose tissue forms profound vascular network through the dynamic reassembly of blood endothelial cells.
Arteriosclerosis, thrombosis, and vascular biology
Koh YJ,Koh BI,Kim H,Joo HJ,Jin HK,Jeon J,Choi C,Lee DH,Chung JH,Cho CH,Park WS,Ryu JK,Suh JK,Koh GY
12-0451 was used in Flow cytometry/Cell sorting to demonstrate that direct implantation of stromal vascular fraction from donor adipose tissue can produce a vascular network through blood endothelial cells at the site of implantation.
Sun May 01 00:00:00 EDT 2011
ER71 directs mesodermal fate decisions during embryogenesis.
Development (Cambridge, England)
Rasmussen TL,Kweon J,Diekmann MA,Belema-Bedada F,Song Q,Bowlin K,Shi X,Ferdous A,Li T,Kyba M,Metzger JM,Koyano-Nakagawa N,Garry DJ
Published figure using CD45 monoclonal antibody (Product # 12-0451-82) in Flow Cytometry
Tue Nov 01 00:00:00 EDT 2011
Reprogramming adult dermis to a neonatal state through epidermal activation of β-catenin.
Development (Cambridge, England)
Collins CA,Kretzschmar K,Watt FM
12-0451 was used in Flow cytometry/Cell sorting to display the plasticity of the characteristics of the dermis in response to cues from the epidermis.
Thu Dec 01 00:00:00 EST 2011
Clonal analysis reveals uniformity in the molecular profile and lineage potential of CCR9(+) and CCR9(-) thymus-settling progenitors.
Journal of immunology (Baltimore, Md. : 1950)
Desanti GE,Jenkinson WE,Parnell SM,Boudil A,Gautreau-Rolland L,Eksteen B,Ezine S,Lane PJ,Jenkinson EJ,Anderson G
12-0451 was used in Flow cytometry/Cell sorting to suggest that the earliest T cell progenitors represent a developmentally homogeneous progenitor pool that ensures the efficient generation of the first cohorts of T cells during thymus development.
Sun May 01 00:00:00 EDT 2011
Effect of topical azithromycin on corneal innate immune responses.
Investigative ophthalmology & visual science
Sadrai Z,Hajrasouliha AR,Chauhan S,Saban DR,Dastjerdi MH,Dana R
Published figure using CD45 monoclonal antibody (Product # 12-0451-82) in Flow Cytometry
Tue Apr 19 00:00:00 EDT 2011
A single mid-gestation exposure to TCDD yields a postnatal autoimmune signature, differing by sex, in early geriatric C57BL/6 mice.
Toxicology
Mustafa A,Holladay SD,Witonsky S,Sponenberg DP,Karpuzoglu E,Gogal RM
12-0451 was used in Flow cytometry/Cell sorting to investigate the effect of prenatal TCDD on the postnatal autoimmune status of C57BL/6 mice.
Sun Dec 18 00:00:00 EST 2011
Myeloid cells migrate in response to IL-24.
Cytokine
Buzas K,Oppenheim JJ,Zack Howard OM
Published figure using CD45 monoclonal antibody (Product # 12-0451-82) in Flow Cytometry
Thu Sep 01 00:00:00 EDT 2011
Fetal muscle contains different CD34+ cell subsets that distinctly differentiate into adipogenic, angiogenic and myogenic lineages.
Stem cell research
Dupas T,Rouaud T,Rouger K,Lieubeau B,Cario-Toumaniantz C,Fontaine-Pérus J,Gardahaut MF,Auda-Boucher G
12-0451 was used in Magnetic cell separation to purify different subsets of CD34(+) cells from fetal mice and analyse their developmental potential in vitro and in vivo.
Tue Nov 01 00:00:00 EDT 2011
Clinical potential of intravenous neural stem cell delivery for treatment of neuroinflammatory disease in mice?
Cell transplantation
Reekmans KP,Praet J,De Vocht N,Tambuyzer BR,Bergwerf I,Daans J,Baekelandt V,Vanhoutte G,Goossens H,Jorens PG,Ysebaert DK,Chatterjee S,Pauwels P,Van Marck E,Berneman ZN,Van der Linden A,Ponsaerts P
Published figure using CD45 monoclonal antibody (Product # 12-0451-82) in Flow Cytometry
Fri Dec 09 00:00:00 EST 2011
Regulatory T cells suppress innate immunity in kidney ischemia-reperfusion injury.
Journal of the American Society of Nephrology : JASN
Kinsey GR,Sharma R,Huang L,Li L,Vergis AL,Ye H,Ju ST,Okusa MD
12-0451 was used in Flow cytometry/Cell sorting to investigate whether the anti-inflammatory effects of CD4(+)CD25(+)FoxP3(+) Tregs protect against renal IRI.
Sat Aug 01 00:00:00 EDT 2009
Pancreatic lipase-related protein 2 (PLRP2) induction by IL-4 in cytotoxic T lymphocytes (CTLs) and reevaluation of the negative effects of its gene ablation on cytotoxicity.
Journal of leukocyte biology
Alves BN,Leong J,Tamang DL,Elliott V,Edelnant J,Redelman D,Singer CA,Kuhn AR,Miller R,Lowe ME,Hudig D
12-0451 was used in Flow cytometry/Cell sorting to study how extracellular PLRP2 lipase is unable to increase the cytotoxicity lost through PLRP2 ablation, and the overall role of PLRP2 in CD8 T cells..
Tue Sep 01 00:00:00 EDT 2009
Deletion of both ICAM-1 and C3 enhances severity of experimental autoimmune encephalomyelitis compared to C3-deficient mice.
Neuroscience letters
Smith SS,Ludwig M,Wohler JE,Bullard DC,Szalai AJ,Barnum SR
12-0451 was used in Flow cytometry/Cell sorting to examine experimental autoimmune encephalitis in ICAM-1 x C3 double knockout mice.
Fri Sep 12 00:00:00 EDT 2008
Optimized isolation enables ex vivo analysis of microglia from various central nervous system regions.
Glia
de Haas AH,Boddeke HW,Brouwer N,Biber K
Published figure using CD45 monoclonal antibody (Product # 12-0451-82) in Flow Cytometry
Mon Oct 01 00:00:00 EDT 2007
Proper levels of c-Myb are discretely defined at distinct steps of hematopoietic cell development.
Blood
Sakamoto H,Dai G,Tsujino K,Hashimoto K,Huang X,Fujimoto T,Mucenski M,Frampton J,Ogawa M
12-0451 was used in Flow cytometry/Cell sorting to investigate the functional role of c-Myb in hematopoietic cell development from endothelial cells, showing that proper levels of c-Myb are discretely defined at distinct steps of development.
Tue Aug 01 00:00:00 EDT 2006
Delayed, asynchronous, and reversible T-lineage specification induced by Notch/Delta signaling.
Genes & development
Taghon TN,David ES,Zúñiga-Pflücker JC,Rothenberg EV
12-0451 was used in Flow cytometry/Cell sorting to study how Notch/Delta signaling is not sufficient for T-lineage specification and commitment, but can be permissive for the maintenance and proliferation of uncommitted progenitors.
Fri Apr 15 00:00:00 EDT 2005