Identify, quantify and verify materials—from incoming inspection through finished product
To ensure product quality and consumer safety, pharmaceutical and biotechnology manufacturers must verify materials throughout production. The Thermo Scientific TruScan G3 Handheld Raman Analyzer uses lab-proven Raman spectroscopy to perform accurate and reliable material identification at the point of need, minimizing the need for costly and time-consuming laboratory sampling tests.
The analyzer’s non-destructive point-and-shoot sampling principle facilitates rapid verification of a broad range of chemical compounds through sealed packaging to minimize the risk of contamination and exposure.
QA/QC applications:
- Incoming raw material identification (RMID)
- Dispensing of materials during API manufacture
- Finished product inspection
Brand security application:
- Identification of falsified (counterfeit) medicines
Improve productivity and efficiency, minimize lab sampling with TruScan Handheld Raman Analyzers using:
Raman spectroscopy
The technology behind TruScan Handheld Raman Analyzers is Raman spectrometry, a type of vibrational spectroscopy that characterizes materials based on measured patterns of vibrational frequencies, or wavelengths. Handheld Raman analyzers emit a laser light at 785nm and detects scattered photons at other wavelengths. The scattered light is a unique fingerprint for that material, and TruScan Handheld Raman Analyzers use this "spectral fingerprint" to identify raw material or finished drug products. The 785nm laser wavelength provides optimal balance for measuring most pharmaceutical materials without compromising spectral resolution or Raman signal intensity.
Patented chemometrics engine
TruScan Handheld Raman Analyzers patented multivariate residual analysis offers the most effective chemometric solution for material identification—with two spectral pre-processing options—that is easy to operate in challenging environments and sampling conditions.
TruScan Handheld Raman Analyzers acquire the Raman spectrum of the material and, in real time, determine the uncertainty of that measurement, given factors such as the sample characteristics, instrument telemetry, environment and testing environment. Since the software models the uncertainty (or in statistical terms, standard deviation) directly, there is no calibration or user modeling involved with method development.
Webinars
Watch on-demand webinar: Lower Bioprocessing Costs and Time with Raman Spectroscopy
From raw material qualification, in-process monitoring to finished product analysis, Raman Spectroscopy offers time and cost savings for bioprocess quality control. Discover how you can optimize your bioprocess workflows with handheld and portable Raman analyzers.
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Watch on-demand webinar: How to save time with TruScan G3 Handheld Raman Analyzer methods
Efficiently conduct raw material ID testing without the constraints of a traditional laboratory using the Thermo Scientific™ TruScan(RM) G3 Handheld Raman Analyzer for exceptional performance and accurate results in any environment. To watch more webinars, click here
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Discover the next generation of raw material ID testing for QA/QC
Learn how the new Thermo Scientific™ TruScan™ G3 Handheld Raman Analyzer uses lab-proven Raman spectroscopy to perform accurate and reliable material identification at the point of need, minimizing the need for costly and time-consuming laboratory sampling tests.
Learn more
Featured resources
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Features & benefits of the TruScan G3 Handheld Raman Analyzer
Search Handheld Raman Resources
| Type | Title |
|---|---|
| Application Note | Discrimination of Povidone and Crospovidone Using a Handheld Raman Analyzer with On-board Chemometrics |
| Application Note | Biologic Drug Identification at Fill and Finish |
| Application Note | Verification of 3 Different Opadry Whites Using a Handheld Raman Analyzer |
| Application Note | Analytical Methods for Field-Based Material Identification and Verification |
| Application Note | Probabilistic Evaluation – First Principles vs. Empirical |
| White Paper | Probabilistic Approach for Material Verification and Identification in Pharmaceutical Applications |
| Specification Sheet | TruScan G3 Handheld Raman Analyzer |
| Specification Sheet | TruScan RM with TruTools |
| Technical note | TruScan RM transferability to TruScan G3 |
| FAQ | TruScan RM Handheld Raman Analyzer for Pharmaceutical Material Identity Verification FAQs |
| FAQ | Raman Spectroscopy Analysis in Pharmaceutical and Drug Manufacturing FAQs |
| eLearning | Raman Technology |
| Pharma and Biotech Manufacturing | Pharma and Biotech Manufacturing |
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