Overview
Advance quantitative workflows and increase productivity
Address current and future challenges with Thermo Scientific TSQ Plus triple quadrupole mass spectrometers, which provide enhanced acquisition speed/sensitivity, proven robustness, and reliability. Instrument choices offer features for a range of applications, from everyday targeted quantitation to cutting-edge research.
Highlights
Achieve the highest confidence in targeted compound detection and quantitation through leading sensitivity
Greater than five orders of linear dynamic range with high selectivity address the diverse needs for targeted quantitative experiments. Enhanced acquisition speeds empower large-scale studies for translational workflow development or method optimization, with 5 millisecond polarity switching to maximize productivity in fewer experiments. Where data confidence is required, the instrumental features on the TSQ Plus triple quadrupole mass spectrometers drive high-performance targeted experiments for complex matrices.
Easy-to-use instrument software to simplify method creation and data acquisition
Instrument control software with pre-built templates, direct importation of existing methods, Thermo Scientific mzCloud database integration, and large-scale method editing capabilities help you quickly set up methods and perform refinements to improve productivity. Intuitive instrument calibration routines streamline instrument checks that automatically determine which calibration routines are performed.
Innovative instrument solutions for targeted data acquisition experimentation
Meet today’s requirements and tomorrow’s challenges with innovative hardware features that provide next-level experimental performance. The new active collision cell improves low-mass product ion transmission that is critical for many routine challenges. Superior acquisition speeds and a new power supply enabling 5 ms polarity switching speeds combine with established robustness and reliability to deliver maximum productivity in the most complex matrices.
LC-MS/MS companion software for integrated productivity
Integrated LC-MS/MS software includes capabilities to create single-reaction monitoring (SRM) assay tables with predicted instrumental parameters, perform data processing to determine optimal experimental parameters, and efficiently and confidently process targeted data with customized reporting. The Thermo Scientific Chromeleon Chromatography Data System (CDS) can also manage all facets of laboratory operations.
Ionization and interface options to extend laboratory capabilities
Because targeted sample analysis methods cover a broad range of compound classes and experimental requirements, laboratories require many options to meet experimental needs, from rapid ionization from biological dried spots, to alternative ionization sources. Differential ion mobility can also be used to overcome background interference to extend dynamic range.
Instruments
Which instrument is right for you?
Robust quantitative performance made simple
TSQ Fortis Plus Mass Spectrometer
Next-level performance combined with robustness and reliability delivering exceptional value for high-throughput analyses.
Accessible extended quantitative performance
TSQ Quantis Plus Mass Spectrometer
Increased sensitivity and performance deliver confident method development and precise quantitation for high-throughput applications.
Ultimate quantitative performance made possible
TSQ Altis Plus Mass Spectrometer
Innovative hardware and software advancements address your most demanding quantitative applications.
Webinars & videos
Meet the TSQ Plus triple quadrupole mass spectrometers
Learn about the new hardware features driving next-level performance for targeted quantitation
The 40-year history of triple quadrupole development
The history of innovative triple quadrupole designs at Thermo Fisher Scientific
Tomorrow’s quantitation today – dynamic duo
The integrated process of connecting knowledge between method development and routine testing
Overcoming the challenges of anti-sports doping
Ludovic Bailly-Chouribery from LCH discusses how the TSQ Altis and Altis Plus MS increase his productivity for anti-sports doping
Routine quantitation for genotoxic impurities
Alan Potts from Patheon discusses the robust and reproducible performance of the TSQ Fortis and Fortis Plus MS to meet the needs for customer requests
Meet the TSQ Plus triple quadrupole mass spectrometers
Learn about the new hardware features driving next-level performance for targeted quantitation
The 40-year history of triple quadrupole development
The history of innovative triple quadrupole designs at Thermo Fisher Scientific
Tomorrow’s quantitation today – dynamic duo
The integrated process of connecting knowledge between method development and routine testing
Overcoming the challenges of anti-sports doping
Ludovic Bailly-Chouribery from LCH discusses how the TSQ Altis and Altis Plus MS increase his productivity for anti-sports doping
Routine quantitation for genotoxic impurities
Alan Potts from Patheon discusses the robust and reproducible performance of the TSQ Fortis and Fortis Plus MS to meet the needs for customer requests
Resources
To perform quantitation assays with confidence, you need a liquid chromatography mass spectrometry (LC-MS) workflow solution that is relevant to your goals
White Paper: Sensitivity and acquisition speed with triple quadrupole technology
Today’s analytical methods performing routine quantitation continue to evolve to meet new environmental and health risks. Experimental methods are modified to include more compounds measured at lower detection levels with faster gradients to address throughput. Therefore, specific LC-MS/MS performance characteristics are critical to evaluate productivity.
White Paper: Triple quadrupole mass spectrometer portfolio
Learn about the hardware and software innovations implemented in the TSQ triple quadrupole mass spectrometer platform to address the current and future challenges in targeted quantitation. The platform enhancements enable ultimate confidence in data quality with robust, reproducible, and reliable quantitative methodologies.
Lab-Forward Trade-In Program
We’ve made trading in your current chromatography, discrete analysis, elemental analysis, sample preparation, and mass spectrometry instruments faster and easier.
LC-MS webinar series
Our webinar series expands your application knowledge for pharma, biopharma, environmental, omics, food, forensics and clinical research and more.
Need help with your grant writing?
Get answers to your questions and access to resources and support to help you write a strong proposal.
Related products
Contact us
Style Sheet for Global Design System
Style Sheet for Komodo Tabs