One Lambda MagSort isolates specific HLA Antibodies using magnetic bead panels to adsorb and elute targeted antibodies.
One Lambda MagSort addresses emerging interests and challenges in adsorption and elution techniques for HLA antibody testing. Targeting individual HLA antigens enables a more focused dataset, to explore and define complex HLA antibody profiles at the antigen-specific level. This novel technology streamlines the process, reducing hands-on time for the laboratory staff, and standardizes a unique isolation approach compared to more cumbersome cell-based approaches.
Capabilities
Targeted technology
- Individual antigen-coated magnetic beads
- Elute antibodies that bind to a specific antigen
- Results in a more focused HLA antibody assessment
Customizable panels
- 59 antigens across 6 locus specific kits
- Flexibility to focus only on antigens of interest
- Coverage across well-documented antigens
Efficient workflow
- Up to 45 minutes of hands-on time and as little as 4 hours to workflow completion
- Uses equipment already found in most laboratories
- Immediate antigen availability.
How does it work?
MagSort example of results before and after isolating A*02:01.
Products & coverage
| MagSort Class II HLA-DRB1 | MagSort Class II HLA-DQ | MagSort Class II HLA-DP | |||
A*01:01 |
B*07:02 |
C*01:02 |
DRB1*01:01 | DQB1*02:01 DQA1*02:01 |
DPB1*01:01 DPA1*01:03 |
A*02:01 |
B*08:01 |
C*02:02 |
DRB1*03:01 |
DQB1*02:02 DQA1*02:01 |
DPB1*02:01 DPA1*01:03 |
A*03:01 |
B*13:01 |
C*03:03 |
DRB1*04:01 |
DQB1*03:01 DQA1*02:01 |
DPB1*03:01 DPA1*01:03 |
A*11:01 |
B*15:01 |
C*03:04 |
DRB1*04:04 |
DQB1*03:02 DQA1*02:01 |
DPB1*04:01 DPA1*01:03 |
A*24:02 |
B*44:02 |
C*04:01 |
DRB1*07:01 |
DQB1*03:03 DQA1*02:01 |
DPB1*04;02 DPA1*01:03 |
A*25:01 |
B*46:01 |
C*05:01 |
DRB1*08:01 |
DQB1*04:01 DQA1*02:01 |
DPB1*11:01 DPA1*01:03 |
| A*29:01 | B*53:01 | C*07:02 | DRB1*11:01 | DQB1*05:01 DQA1*01:01 |
DPB1*17:01 DPA1*02:01 |
| A*30:01 | B*57:01 | C*12:03 | DRB1*12:01 | DQB1*06:02 DQA1*01:01 |
DPB1*19:01 DPA1*01:03 |
| A*33:03 | B*67:01 | C*15:02 | DRB1*13:01 | DQB1*06:03 DQA1*01:03 |
|
| A*68:01 | B*73:01 | C*16:01 | DRB1*15:01 | ||
| C*17:01 | DRB1*16:01 |
For research use or further manufacturing. Not for diagnostic use or direct administration into humans or animals.