Product References
EB1 decoration of microtubule lattice facilitates spindle-kinetochore lateral attachment in Plasmodium male gametogenesis.
Nature communications
Yang S,Cai M,Huang J,Zhang S,Mo X,Jiang K,Cui H,Yuan J
MA1-80017 was used in Immunohistochemistry to study the mechanisms underlying the spindle-kinetochore attachment.
Fri May 19 00:00:00 EDT 2023
A quick, cheap, and reliable protocol for immunofluorescence of pluripotent and differentiating mouse embryonic stem cells in 2D and 3D colonies.
STAR protocols
Kodba S,Chaigne A
MA1-80017 was used in ELISA, Immunocytochemistry, Immunohistochemistry (Frozen), Immunoprecipitation, Radioimmune assays, Western Blot to propose a half-a-day, cheap, easy-to-follow, and reproducible protocol for immunofluorescence of mESCs.
Fri Mar 17 00:00:00 EDT 2023
Colchicine exerts anti-atherosclerotic and -plaque-stabilizing effects targeting foam cell formation.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Schwarz N,Fernando S,Chen YC,Salagaras T,Rao SR,Liyanage S,Williamson AE,Toledo-Flores D,Dimasi C,Sargeant TJ,Manavis J,Eddy E,Kanellakis P,Thompson PL,Tan JTM,Snel MF,Bursill CA,Nicholls SJ,Peter K,Psaltis PJ
MA1-80017 was used in Western Blot to show that colchicine exerts anti-atherosclerotic and plaque-stabilizing effects at low dose by inhibiting foam cell formation and cholesterol crystal-induced inflammation.
Sat Apr 01 00:00:00 EDT 2023
Septin-microtubule association via a motif unique to isoform 1 of septin 9 tunes stress fibers.
Journal of cell science
Kuzmić M,Castro Linares G,Leischner Fialová J,Iv F,Salaün D,Llewellyn A,Gomes M,Belhabib M,Liu Y,Asano K,Rodrigues M,Isnardon D,Tachibana T,Koenderink GH,Badache A,Mavrakis M,Verdier-Pinard P
MA1-80017 was used in Immunocytochemistry to dentify key molecular determinants and potential regulatory roles of septin-microtubule interaction, paving the way to deciphering the mechanisms underlying septin-associated pathologies.
Sat Jan 01 00:00:00 EST 2022
Deprogramming metabolism in pancreatic cancer with a bi-functional GPR55 inhibitor and biased β2 adrenergic agonist.
Scientific reports
Wnorowski A,Dudzik D,Bernier M,Wójcik J,Keijzers G,Diaz-Ruiz A,Mazur K,Zhang Y,Han H,Scheibye-Knudsen M,Jozwiak K,Barbas C,Wainer IW
MA1-80017 was used in Western Blot to indicate a potential benefit of combined GPR55 antagonism and biased β2-AR agonism in PDAC therapy associated with the deprogramming of altered cellular metabolism.
Mon Mar 07 00:00:00 EST 2022
Deprogramming metabolism in pancreatic cancer with a bi-functional GPR55 inhibitor and biased β2 adrenergic agonist.
Scientific reports
Wnorowski A,Dudzik D,Bernier M,Wójcik J,Keijzers G,Diaz-Ruiz A,Mazur K,Zhang Y,Han H,Scheibye-Knudsen M,Jozwiak K,Barbas C,Wainer IW
MA1-80017 was used in Western Blot to indicate a potential benefit of combined GPR55 antagonism and biased β2-AR agonism in PDAC therapy associated with the deprogramming of altered cellular metabolism.
Mon Mar 07 00:00:00 EST 2022
Kinetochore- and chromosome-driven transition of microtubules into bundles promotes spindle assembly.
Nature communications
Matković J,Ghosh S,Ćosić M,Eibes S,Barišić M,Pavin N,Tolić IM
MA1-80017 was used in ELISA, Immunocytochemistry, Immunohistochemistry (Frozen), Immunoprecipitation, Radioimmune assays, Western Blot to show that overlap bundles arise through a network-to-bundles transition driven by kinetochores and chromosomes and that kinetochores and chromosomes drive coarsening of a uniform microtubule array into overlap bundles, which promote not only spindle formation but also chromosome segregation fidelity.
Sun Nov 27 00:00:00 EST 2022
CHD1 Promotes Sensitivity to Aurora Kinase Inhibitors by Suppressing Interaction of AURKA with Its Coactivator TPX2.
Cancer research
Li H,Wang Y,Lin K,Venkadakrishnan VB,Bakht M,Shi W,Meng C,Zhang J,Tremble K,Liang X,Song JH,Feng X,Van V,Deng P,Burks JK,Aparicio A,Keyomarsi K,Chen J,Lu Y,Beltran H,Zhao D
MA1-80017 was used in Immunohistochemistry-immunofluorescence to demonstrate that CHD1 plays an important role in modulating Aurora kinases and drug sensitivities, providing new insights into biomarker-driven therapies targeting Aurora kinases for future clinical studies.
Fri Sep 02 00:00:00 EDT 2022
Reconstitution and mechanistic dissection of the human microtubule branching machinery.
The Journal of cell biology
Zhang Y,Hong X,Hua S,Jiang K
MA1-80017 was used in ELISA, Immunocytochemistry, Immunohistochemistry (Frozen), Immunoprecipitation, Radioimmune assays, Western Blot to investigate molecular factors and regulation in branching microtubule reactions.
Mon Jul 04 00:00:00 EDT 2022
Structure-activity assessment of flavonoids as modulators of copper transport.
Frontiers in chemistry
Lee VJ,Heffern MC
MA1-80017 was used in ELISA, Immunocytochemistry, Immunohistochemistry (Frozen), Immunoprecipitation, Radioimmune assays, Western Blot to identify structural moieties important in flavonoid-copper interactions which relate to ring substitution but not the traditional structural subclassifications.
Mon Sep 12 00:00:00 EDT 2022
MKLP2 functions in early mitosis to ensure proper chromosome congression.
Journal of cell science
Schrock MS,Scarberry L,Stromberg BR,Sears C,Torres AE,Tallman D,Krupinski L,Chakravarti A,Summers MK
MA1-80017 was used in Immunocytochemistry-immunofluorescence to provide direct evidence that MKLP2 facilitates chromosome congression in prometaphase.
Wed Jun 15 00:00:00 EDT 2022
A cell-penetrating peptide enhances delivery and efficacy of phosphorodiamidate morpholino oligomers in mdx mice.
Molecular therapy. Nucleic acids
Gan L,Wu LCL,Wood JA,Yao M,Treleaven CM,Estrella NL,Wentworth BM,Hanson GJ,Passini MA
MA1-80017 was used in Immunohistochemistry-immunofluorescence to demonstrate that a single-dose RC-1001 increases exon skipping and dytrophin levels in striated muscles in a dose dependant manner to increase muscle function.
Tue Dec 13 00:00:00 EST 2022
Centriole signaling restricts hepatocyte ploidy to maintain liver integrity.
Genes & development
Sladky VC,Akbari H,Tapias-Gomez D,Evans LT,Drown CG,Strong MA,LoMastro GM,Larman T,Holland AJ
MA1-80017 was used in Immunohistochemistry-immunofluorescence to show that hyperpolyploidization sensitizes the liver to injury, posing a trade-off for the cancer-protective effect of increased hepatocyte ploidy.
Thu Aug 18 00:00:00 EDT 2022
Posttranslational modification of microtubules by the MATCAP detyrosinase.
Science (New York, N.Y.)
Landskron L,Bak J,Adamopoulos A,Kaplani K,Moraiti M,van den Hengel LG,Song JY,Bleijerveld OB,Nieuwenhuis J,Heidebrecht T,Henneman L,Moutin MJ,Barisic M,Taraviras S,Perrakis A,Brummelkamp TR
MA1-80017 was used in ELISA, Immunocytochemistry, Immunohistochemistry (Frozen), Immunoprecipitation, Radioimmune assays, Western Blot, Flow Cytometry to show that MATCAP is a missing component of the detyrosination-tyrosination cycle, revealing the importance of this modification in brain formation.
Fri May 20 00:00:00 EDT 2022
Light-Seq: light-directed in situ barcoding of biomolecules in fixed cells and tissues for spatially indexed sequencing.
Nature methods
Kishi JY,Liu N,West ER,Sheng K,Jordanides JJ,Serrata M,Cepko CL,Saka SK,Yin P
MA1-80017 was used in ELISA, Immunocytochemistry, Immunohistochemistry (Frozen), Immunoprecipitation, Radioimmune assays, Western Blot to present Light-Seq, an approach for multiplexed spatial indexing of intact biological samples using light-directed DNA barcoding in fixed cells and tissues followed by ex situ sequencing.
Tue Nov 01 00:00:00 EDT 2022
Self-assembly of pericentriolar material in interphase cells lacking centrioles.
eLife
Chen F,Wu J,Iwanski MK,Jurriens D,Sandron A,Pasolli M,Puma G,Kromhout JZ,Yang C,Nijenhuis W,Kapitein LC,Berger F,Akhmanova A
MA1-80017 was used in Immunocytochemistry-immunofluorescence to reveal that interphase PCM contains a set of components that can self-assemble into a compact structure and organize microtubules, but PCM self-organization is sensitive to motor- and microtubule-based rearrangement.
Tue Jul 05 00:00:00 EDT 2022
Engineered Wnt ligands enable blood-brain barrier repair in neurological disorders.
Science (New York, N.Y.)
Martin M,Vermeiren S,Bostaille N,Eubelen M,Spitzer D,Vermeersch M,Profaci CP,Pozuelo E,Toussay X,Raman-Nair J,Tebabi P,America M,De Groote A,Sanderson LE,Cabochette P,Germano RFV,Torres D,Boutry S,de Kerchove d'Exaerde A,Bellefroid EJ,Phoenix TN,Devraj K,Lacoste B,Daneman R,Liebner S,Vanhollebeke B
MA1-80017 was used in Western Blotting to reveal that the signaling specificity of Wnt ligands is adjustable and defines a modality to treat CNS disorders by normalizing the BBB.
Fri Feb 18 00:00:00 EST 2022
Expression of Constitutive Fusion of Ubiquitin to PCNA Restores the Level of Immunoglobulin A/T Mutations During Somatic Hypermutation in the Ramos Cell Line.
Frontiers in immunology
Lerner LK,Bonte D,Le Guillou M,Mohammad MM,Kasraian Z,Sarasin A,Despras E,Aoufouchi S
MA1-80017 was used in Western Blotting to report the establishment of the first modified human B cell line that recapitulates the mechanism of SHM of Ig genes in vitro.
Tue Apr 19 00:00:00 EDT 2022
Multi-omic profiling reveals the ataxia protein sacsin is required for integrin trafficking and synaptic organization.
Cell reports
Romano LEL,Aw WY,Hixson KM,Novoselova TV,Havener TM,Howell S,Taylor-Blake B,Hall CL,Xing L,Beri J,Nethisinghe S,Perna L,Hatimy A,Altadonna GC,Graves LM,Herring LE,Hickey AJ,Thalassinos K,Chapple JP,Wolter JM
MA1-80017 was used in Immunocytochemistry-immunofluorescence to suggest that disrupted trafficking of synaptic adhesion proteins is a causal molecular deficit in ARSACS.
Tue Nov 01 00:00:00 EDT 2022
Augmin prevents merotelic attachments by promoting proper arrangement of bridging and kinetochore fibers.
eLife
Štimac V,Koprivec I,Manenica M,Simunić J,Tolić IM
MA1-80017 was used in Immunocytochemistry-immunofluorescence to analyze the previously indistinguishable microtubule arrangements within the crowded metaphase plate area and demonstrate that augmin is vital for the formation of uniformly arranged parallel units consisting of sister kinetochore fibers connected by a bridging fiber.
Fri Oct 21 00:00:00 EDT 2022
Development of human-derived, three-dimensional respiratory epithelial tissue constructs with perfusable microvasculature on a high-throughput microfluidics screening platform.
Biofabrication
Jung O,Tung YT,Sim E,Chen YC,Lee E,Ferrer M,Song MJ
MA1-80017 was used in Immunohistochemistry-immunofluorescence to develop two novel vascularized, LRT multi-chip models for the alveoli and the small airway.
Mon Feb 14 00:00:00 EST 2022
Centrosome defects cause microcephaly by activating the 53BP1-USP28-TP53 mitotic surveillance pathway.
The EMBO journal
Phan TP,Maryniak AL,Boatwright CA,Lee J,Atkins A,Tijhuis A,Spierings DC,Bazzi H,Foijer F,Jordan PW,Stracker TH,Holland AJ
Published figure using alpha Tubulin monoclonal antibody (Product # MA1-80017) in Immunohistochemistry
Mon Jan 04 00:00:00 EST 2021
Centrosome defects cause microcephaly by activating the 53BP1-USP28-TP53 mitotic surveillance pathway.
The EMBO journal
Phan TP,Maryniak AL,Boatwright CA,Lee J,Atkins A,Tijhuis A,Spierings DC,Bazzi H,Foijer F,Jordan PW,Stracker TH,Holland AJ
Published figure using alpha Tubulin monoclonal antibody (Product # MA1-80017) in Immunohistochemistry
Mon Jan 04 00:00:00 EST 2021
A regulatory phosphorylation site on Mec1 controls chromatin occupancy of RNA polymerases during replication stress.
The EMBO journal
Hurst V,Challa K,Jonas F,Forey R,Sack R,Seebacher J,Schmid CD,Barkai N,Shimada K,Gasser SM,Poli J
Published figure using alpha Tubulin monoclonal antibody (Product # MA1-80017) in Western Blot
Tue Nov 02 00:00:00 EDT 2021
ANKRD26 recruits PIDD1 to centriolar distal appendages to activate the PIDDosome following centrosome amplification.
The EMBO journal
Evans LT,Anglen T,Scott P,Lukasik K,Loncarek J,Holland AJ
MA1-80017 was used in Western Blot to identify centriole distal appendages as critical for PIDDosome activation in cells with extra centrosomes.
Mon Feb 15 00:00:00 EST 2021
Microtubule-sliding modules based on kinesins EG5 and PRC1-dependent KIF4A drive human spindle elongation.
Developmental cell
Vukušić K,Ponjavić I,Buđa R,Risteski P,Tolić IM
MA1-80017 was used in Immunocytochemistry-immunoflourescence to discover that the force-generating mechanism of spindle elongation consists of EG5/kinesin-5 together with the PRC1-dependent motor KIF4A/kinesin-4, with contribution from kinesin-6 and kinesin-8.
Mon May 03 00:00:00 EDT 2021
Microtubule-sliding modules based on kinesins EG5 and PRC1-dependent KIF4A drive human spindle elongation.
Developmental cell
Vukušić K,Ponjavić I,Buđa R,Risteski P,Tolić IM
MA1-80017 was used in Immunocytochemistry-immunoflourescence to discover that the force-generating mechanism of spindle elongation consists of EG5/kinesin-5 together with the PRC1-dependent motor KIF4A/kinesin-4, with contribution from kinesin-6 and kinesin-8.
Mon May 03 00:00:00 EDT 2021
Evolutionarily related small viral fusogens hijack distinct but modular actin nucleation pathways to drive cell-cell fusion.
Proceedings of the National Academy of Sciences of the United States of America
Chan KMC,Arthur AL,Morstein J,Jin M,Bhat A,Schlesinger D,Son S,Stevens DA,Drubin DG,Fletcher DA
Published figure using alpha Tubulin monoclonal antibody (Product # MA1-80017) in Western Blot
Tue Jan 05 00:00:00 EST 2021
Evolutionarily related small viral fusogens hijack distinct but modular actin nucleation pathways to drive cell-cell fusion.
Proceedings of the National Academy of Sciences of the United States of America
Chan KMC,Arthur AL,Morstein J,Jin M,Bhat A,Schlesinger D,Son S,Stevens DA,Drubin DG,Fletcher DA
Published figure using alpha Tubulin monoclonal antibody (Product # MA1-80017) in Western Blot
Tue Jan 05 00:00:00 EST 2021
The Trypanosoma brucei subpellicular microtubule array is organized into functionally discrete subdomains defined by microtubule associated proteins.
PLoS pathogens
Sinclair AN,Huynh CT,Sladewski TE,Zuromski JL,Ruiz AE,de Graffenried CL
Published figure using alpha Tubulin monoclonal antibody (Product # MA1-80017) in Western Blot
Sat May 01 00:00:00 EDT 2021
The Trypanosoma brucei subpellicular microtubule array is organized into functionally discrete subdomains defined by microtubule associated proteins.
PLoS pathogens
Sinclair AN,Huynh CT,Sladewski TE,Zuromski JL,Ruiz AE,de Graffenried CL
Published figure using alpha Tubulin monoclonal antibody (Product # MA1-80017) in Western Blot
Sat May 01 00:00:00 EDT 2021
The Trypanosoma brucei subpellicular microtubule array is organized into functionally discrete subdomains defined by microtubule associated proteins.
PLoS pathogens
Sinclair AN,Huynh CT,Sladewski TE,Zuromski JL,Ruiz AE,de Graffenried CL
Published figure using alpha Tubulin monoclonal antibody (Product # MA1-80017) in Western Blot
Sat May 01 00:00:00 EDT 2021
The Trypanosoma brucei subpellicular microtubule array is organized into functionally discrete subdomains defined by microtubule associated proteins.
PLoS pathogens
Sinclair AN,Huynh CT,Sladewski TE,Zuromski JL,Ruiz AE,de Graffenried CL
Published figure using alpha Tubulin monoclonal antibody (Product # MA1-80017) in Western Blot
Sat May 01 00:00:00 EDT 2021
TGF-β1 increases permeability of ciliated airway epithelia via redistribution of claudin 3 from tight junction into cell nuclei.
Pflugers Archiv : European journal of physiology
Schilpp C,Lochbaum R,Braubach P,Jonigk D,Frick M,Dietl P,Wittekindt OH
MA1-80017 was used in Immunocytochemistry to conclude that the observed effects contribute to loss of epithelial integrity during atopic asthma.
Mon Feb 01 00:00:00 EST 2021
TGF-β1 increases permeability of ciliated airway epithelia via redistribution of claudin 3 from tight junction into cell nuclei.
Pflugers Archiv : European journal of physiology
Schilpp C,Lochbaum R,Braubach P,Jonigk D,Frick M,Dietl P,Wittekindt OH
MA1-80017 was used in Immunocytochemistry to conclude that the observed effects contribute to loss of epithelial integrity during atopic asthma.
Mon Feb 01 00:00:00 EST 2021
Mapping the degradation pathway of a disease-linked aspartoacylase variant.
PLoS genetics
Gersing SK,Wang Y,Grønbæk-Thygesen M,Kampmeyer C,Clausen L,Willemoës M,Andréasson C,Stein A,Lindorff-Larsen K,Hartmann-Petersen R
Published figure using alpha Tubulin monoclonal antibody (Product # MA1-80017) in Western Blot
Thu Apr 01 00:00:00 EDT 2021
Elp2 mutations perturb the epitranscriptome and lead to a complex neurodevelopmental phenotype.
Nature communications
Kojic M,Gawda T,Gaik M,Begg A,Salerno-Kochan A,Kurniawan ND,Jones A,Drożdżyk K,Kościelniak A,Chramiec-Głąbik A,Hediyeh-Zadeh S,Kasherman M,Shim WJ,Sinniah E,Genovesi LA,Abrahamsen RK,Fenger CD,Madsen CG,Cohen JS,Fatemi A,Stark Z,Lunke S,Lee J,Hansen JK,Boxill MF,Keren B,Marey I,Saenz MS,Brown K,Alexander SA,Mureev S,Batzilla A,Davis MJ,Piper M,Bodén M,Burne THJ,Palpant NJ,Møller RS,Glatt S,Wainwright BJ
MA1-80017 was used in ELISA, Immunocytochemistry, Immunohistochemistry (Frozen), Immunoprecipitation, Radioimmune assays, Western Blot to identify biallelic variants in the gene encoding one of the Elongator complex subunits, ELP2, in patients with ID and ASD.
Tue May 11 00:00:00 EDT 2021
Pharmacological activation of STING blocks SARS-CoV-2 infection.
Science immunology
Li M,Ferretti M,Ying B,Descamps H,Lee E,Dittmar M,Lee JS,Whig K,Kamalia B,Dohnalová L,Uhr G,Zarkoob H,Chen YC,Ramage H,Ferrer M,Lynch K,Schultz DC,Thaiss CA,Diamond MS,Cherry S
MA1-80017 was used in Immunocytochemistry to provide evidence that activation of STING may represent a promising therapeutic strategy to control SARS-CoV-2.
Tue May 18 00:00:00 EDT 2021
A genetically tractable jellyfish model for systems and evolutionary neuroscience.
Cell
Weissbourd B,Momose T,Nair A,Kennedy A,Hunt B,Anderson DJ
MA1-80017 was used in ELISA, Immunocytochemistry, Immunohistochemistry (Frozen), Immunoprecipitation, Radioimmune assays, Western Blot to introduce Clytia hemisphaerica as a transparent, genetically tractable jellyfish model for systems and generate stable F1 transgenic lines for cell-type-specific conditional ablation and whole-organism GCaMP imaging.
Wed Nov 24 00:00:00 EST 2021
TPR is required for the efficient nuclear export of mRNAs and lncRNAs from short and intron-poor genes.
Nucleic acids research
Lee ES,Wolf EJ,Ihn SSJ,Smith HW,Emili A,Palazzo AF
MA1-80017 was used in Western Blot, Immunocytochemistry to investigate the role of the major nuclear pore basket protein, TPR, in regulating mRNA and lncRNA nuclear export in human cells. By sequencing mRNA from the nucleus and cytosol of control and TPR-depleted cells, we provide evidence that TPR is required for the efficient nuclear export of mRNAs and lncRNAs that are generated from short transcripts that tend to have few introns, and we validate this with reporter constructs.
Wed Nov 18 00:00:00 EST 2020
TPR is required for the efficient nuclear export of mRNAs and lncRNAs from short and intron-poor genes.
Nucleic acids research
Lee ES,Wolf EJ,Ihn SSJ,Smith HW,Emili A,Palazzo AF
MA1-80017 was used in Western Blot, Immunocytochemistry to investigate the role of the major nuclear pore basket protein, TPR, in regulating mRNA and lncRNA nuclear export in human cells. By sequencing mRNA from the nucleus and cytosol of control and TPR-depleted cells, we provide evidence that TPR is required for the efficient nuclear export of mRNAs and lncRNAs that are generated from short transcripts that tend to have few introns, and we validate this with reporter constructs.
Wed Nov 18 00:00:00 EST 2020
TPR is required for the efficient nuclear export of mRNAs and lncRNAs from short and intron-poor genes.
Nucleic acids research
Lee ES,Wolf EJ,Ihn SSJ,Smith HW,Emili A,Palazzo AF
MA1-80017 was used in Western Blot, Immunocytochemistry to investigate the role of the major nuclear pore basket protein, TPR, in regulating mRNA and lncRNA nuclear export in human cells. By sequencing mRNA from the nucleus and cytosol of control and TPR-depleted cells, we provide evidence that TPR is required for the efficient nuclear export of mRNAs and lncRNAs that are generated from short transcripts that tend to have few introns, and we validate this with reporter constructs.
Wed Nov 18 00:00:00 EST 2020
A drug discovery platform to identify compounds that inhibit EGFR triple mutants.
Nature chemical biology
Saraon P,Snider J,Kalaidzidis Y,Wybenga-Groot LE,Weiss K,Rai A,Radulovich N,Drecun L,Vučković N,Vučetić A,Wong V,Thériault B,Pham NA,Park JH,Datti A,Wang J,Pathmanathan S,Aboualizadeh F,Lyakisheva A,Yao Z,Wang Y,Joseph B,Aman A,Moran MF,Prakesch M,Poda G,Marcellus R,Uehling D,Samaržija M,Jakopović M,Tsao MS,Shepherd FA,Sacher A,Leighl N,Akhmanova A,Al-Awar R,Zerial M,Stagljar I
MA1-80017 was used in Immunocytochemistry to demonstrate how MaMTH-DS is a powerful complement to traditional drug screening approaches.
Fri May 01 00:00:00 EDT 2020
Abscission Couples Cell Division to Embryonic Stem Cell Fate.
Developmental cell
Chaigne A,Labouesse C,White IJ,Agnew M,Hannezo E,Chalut KJ,Paluch EK
Published figure using alpha Tubulin monoclonal antibody (Product # MA1-80017) in Immunocytochemistry
Mon Oct 26 00:00:00 EDT 2020
Abscission Couples Cell Division to Embryonic Stem Cell Fate.
Developmental cell
Chaigne A,Labouesse C,White IJ,Agnew M,Hannezo E,Chalut KJ,Paluch EK
Published figure using alpha Tubulin monoclonal antibody (Product # MA1-80017) in Immunocytochemistry
Mon Oct 26 00:00:00 EDT 2020
A G protein-coupled receptor mediates neuropeptide-induced oocyte maturation in the jellyfish Clytia.
PLoS biology
Quiroga Artigas G,Lapébie P,Leclère L,Bauknecht P,Uveira J,Chevalier S,Jékely G,Momose T,Houliston E
MA1-80017 was used in Immunohistochemistry (PFA fixed) to identify the MIHR in the hydrozoan jellyfish Clytia hemisphaerica as a GPCR likely working through Gαs, and determine its in vivo function.
Sun Mar 01 00:00:00 EST 2020
Injection molded open microfluidic well plate inserts for user-friendly coculture and microscopy.
Lab on a chip
Day JH,Nicholson TM,Su X,van Neel TL,Clinton I,Kothandapani A,Lee J,Greenberg MH,Amory JK,Walsh TJ,Muller CH,Franco OE,Jefcoate CR,Crawford SE,Jorgensen JS,Theberge AB
MA1-80017 was used in Immunocytochemistry to present use cases of two new injection molded open microfluidic devices, including culture of limited primary testis cells from surgical patients, microscopy readouts including immunocytochemistry and single molecule fluorescence in situ hybridization (smFISH), and coculture to study interactions between adipocytes and prostate cancer cells, which also easily insert into standard cell culture well plates and standard culture workflows.
Tue Jan 07 00:00:00 EST 2020
Heat stress interferes with chromosome segregation and cytokinesis during male meiosis in Arabidopsis thaliana.
Plant signaling & behavior
Lei X,Ning Y,Eid Elesawi I,Yang K,Chen C,Wang C,Liu B
MA1-80017 was used in Immunohistochemistry-immunofluorescence to demonstrate that an extremely high-temperature stress over the fertile threshold affects both chromosome segregation and cytokinesis during male meiosis by disturbing microtubular cytoskeleton in Arabidopsis.
Sun May 03 00:00:00 EDT 2020
Bone marrow adipose tissue is a unique adipose subtype with distinct roles in glucose homeostasis.
Nature communications
Suchacki KJ,Tavares AAS,Mattiucci D,Scheller EL,Papanastasiou G,Gray C,Sinton MC,Ramage LE,McDougald WA,Lovdel A,Sulston RJ,Thomas BJ,Nicholson BM,Drake AJ,Alcaide-Corral CJ,Said D,Poloni A,Cinti S,Macpherson GJ,Dweck MR,Andrews JPM,Williams MC,Wallace RJ,van Beek EJR,MacDougald OA,Morton NM,Stimson RH,Cawthorn WP
MA1-80017 was used in Western Blotting to reveal that bone marrow adipose tissue is distinct from white adipose tissues and brown adipose tissues, with altered glucose metabolism and decreased insulin responsiveness.
Thu Jun 18 00:00:00 EDT 2020
Bone marrow adipose tissue is a unique adipose subtype with distinct roles in glucose homeostasis.
Nature communications
Suchacki KJ,Tavares AAS,Mattiucci D,Scheller EL,Papanastasiou G,Gray C,Sinton MC,Ramage LE,McDougald WA,Lovdel A,Sulston RJ,Thomas BJ,Nicholson BM,Drake AJ,Alcaide-Corral CJ,Said D,Poloni A,Cinti S,Macpherson GJ,Dweck MR,Andrews JPM,Williams MC,Wallace RJ,van Beek EJR,MacDougald OA,Morton NM,Stimson RH,Cawthorn WP
MA1-80017 was used in Western Blotting to reveal that bone marrow adipose tissue is distinct from white adipose tissues and brown adipose tissues, with altered glucose metabolism and decreased insulin responsiveness.
Thu Jun 18 00:00:00 EDT 2020
Feature-rich covalent stains for super-resolution and cleared tissue fluorescence microscopy.
Science advances
Mao C,Lee MY,Jhan JR,Halpern AR,Woodworth MA,Glaser AK,Chozinski TJ,Shin L,Pippin JW,Shankland SJ,Liu JTC,Vaughan JC
MA1-80017 was used in Immunocytochemistry to report the use of conventional, commercially available fluorescent dyes for rapid and intense covalent labeling of proteins and carbohydrates in super-resolution (expansion) microscopy and cleared tissue microscopy.
Fri May 01 00:00:00 EDT 2020
An Antiparasitic Compound from the Medicines for Malaria Venture Pathogen Box Promotes Leishmania Tubulin Polymerization.
ACS infectious diseases
Ullah I,Gahalawat S,Booshehri LM,Niederstrasser H,Majumdar S,Leija C,Bradford JM,Hu B,Ready JM,Wetzel DM
MA1-80017 was used in Immunocytochemistry to demonstrate that MMV676477 is a potent antiparasitic compound that preferentially promotes Leishmania microtubule polymerization.
Fri Aug 14 00:00:00 EDT 2020
Global proteomic analysis of insulin receptor interactors in glomerular podocytes.
Wellcome open research
Hosawi SB,Humphries JD,Coward RJ,Knight D,Humphries MJ,Lennon R
MA1-80017 was used in Western Blotting to define the literature-based insulin receptor (INSR) interactome and utilised an unbiased proteomic approach to examine INSR interactors in podocytes.
Wed Mar 02 00:00:00 EST 2022
FluoSim: simulator of single molecule dynamics for fluorescence live-cell and super-resolution imaging of membrane proteins.
Scientific reports
Lagardère M,Chamma I,Bouilhol E,Nikolski M,Thoumine O
MA1-80017 was used in Immunocytochemistry-immunoflourescence to allow one to model and predict membrane protein dynamics and localization at the ensemble and single molecule level, so as to reconcile imaging paradigms and quantitatively characterize protein behavior in complex cellular environments.
Tue Nov 17 00:00:00 EST 2020
PLK1 plays dual roles in centralspindlin regulation during cytokinesis.
The Journal of cell biology
Adriaans IE,Basant A,Ponsioen B,Glotzer M,Lens SMA
MA1-80017 was used in Immunocytochemistry-immunoflourescence to understand the effect PLK1 has during cytokinesis via centralspindlin regulation.
Mon Apr 01 00:00:00 EDT 2019
An order of magnitude faster DNA-PAINT imaging by optimized sequence design and buffer conditions.
Nature methods
Schueder F,Stein J,Stehr F,Auer A,Sperl B,Strauss MT,Schwille P,Jungmann R
MA1-80017 was used in Immunohistochemistry to exhibit acquisition of images from DNA-PAINT at an order of magnitude faster speed without compromising quality or spatial resolution.
Fri Nov 01 00:00:00 EDT 2019
An order of magnitude faster DNA-PAINT imaging by optimized sequence design and buffer conditions.
Nature methods
Schueder F,Stein J,Stehr F,Auer A,Sperl B,Strauss MT,Schwille P,Jungmann R
MA1-80017 was used in Immunohistochemistry to exhibit acquisition of images from DNA-PAINT at an order of magnitude faster speed without compromising quality or spatial resolution.
Fri Nov 01 00:00:00 EDT 2019
An order of magnitude faster DNA-PAINT imaging by optimized sequence design and buffer conditions.
Nature methods
Schueder F,Stein J,Stehr F,Auer A,Sperl B,Strauss MT,Schwille P,Jungmann R
MA1-80017 was used in Immunohistochemistry to exhibit acquisition of images from DNA-PAINT at an order of magnitude faster speed without compromising quality or spatial resolution.
Fri Nov 01 00:00:00 EDT 2019
A tessellation-based colocalization analysis approach for single-molecule localization microscopy.
Nature communications
Levet F,Julien G,Galland R,Butler C,Beghin A,Chazeau A,Hoess P,Ries J,Giannone G,Sibarita JB
MA1-80017 was used in Blocking experiments to present an efficient, parameter-free colocalization analysis method for 2D and 3D λSMLM using tessellation analysis.
Thu May 30 00:00:00 EDT 2019
Fundamentals of rapid injection molding for microfluidic cell-based assays.
Lab on a chip
Lee UN,Su X,Guckenberger DJ,Dostie AM,Zhang T,Berthier E,Theberge AB
MA1-80017 was used in Immunocytochemistry to characterize advantages and limitations of rapid injection molding for microfluidic device fabrication through measurement of key features for cell culture applications including channel geometry, feature consistency, floor thickness, and surface polishing.
Tue Jan 30 00:00:00 EST 2018
Structural Basis of Formation of the Microtubule Minus-End-Regulating CAMSAP-Katanin Complex.
Structure (London, England : 1993)
Jiang K,Faltova L,Hua S,Capitani G,Prota AE,Landgraf C,Volkmer R,Kammerer RA,Steinmetz MO,Akhmanova A
MA1-80017 was used in Western Blotting to reveal that a short helical motif conserved in CAMSAP2 and CAMSAP3 binds to heterodimer formed by mutational analysis and genome-editing experiments.
Tue Mar 06 00:00:00 EST 2018
Control of endothelial cell polarity and sprouting angiogenesis by non-centrosomal microtubules.
eLife
Martin M,Veloso A,Wu J,Katrukha EA,Akhmanova A
Published figure using alpha Tubulin monoclonal antibody (Product # MA1-80017) in Western Blot
Fri Mar 16 00:00:00 EDT 2018
A gonad-expressed opsin mediates light-induced spawning in the jellyfish Clytia.
eLife
Quiroga Artigas G,Lapébie P,Leclère L,Takeda N,Deguchi R,Jékely G,Momose T,Houliston E
MA1-80017 was used in Immunohistochemistry to identify a cnidarian opsin gene expressed in the gonads of Clytia hemisphaerica and show that it is essential for spawning via maturation-inducing neuropeptide hormone release in response to light.
Fri Jan 05 00:00:00 EST 2018
Nanometer-scale Multiplexed Super-Resolution Imaging with an Economic 3D-DNA-PAINT Microscope.
Chemphyschem : a European journal of chemical physics and physical chemistry
Auer A,Schlichthaerle T,Woehrstein JB,Schueder F,Strauss MT,Grabmayr H,Jungmann R
MA1-80017 was used in Immunocytochemistry-immunofluorescence to introduce a combination of the recently developed super-resolution technique DNA-PAINT (DNA points accumulation for imaging in nanoscale topography) with an easy-to-replicate, custom-built 3D single-molecule microscope (termed liteTIRF) that is an order of magnitude more economic in cost compared to most commercial systems.
Mon Nov 19 00:00:00 EST 2018
Nanometer-scale Multiplexed Super-Resolution Imaging with an Economic 3D-DNA-PAINT Microscope.
Chemphyschem : a European journal of chemical physics and physical chemistry
Auer A,Schlichthaerle T,Woehrstein JB,Schueder F,Strauss MT,Grabmayr H,Jungmann R
MA1-80017 was used in Immunocytochemistry-immunofluorescence to introduce a combination of the recently developed super-resolution technique DNA-PAINT (DNA points accumulation for imaging in nanoscale topography) with an easy-to-replicate, custom-built 3D single-molecule microscope (termed liteTIRF) that is an order of magnitude more economic in cost compared to most commercial systems.
Mon Nov 19 00:00:00 EST 2018
Rapid Sequential in Situ Multiplexing with DNA Exchange Imaging in Neuronal Cells and Tissues.
Nano letters
Wang Y,Woehrstein JB,Donoghue N,Dai M,Avendaño MS,Schackmann RCJ,Zoeller JJ,Wang SSH,Tillberg PW,Park D,Lapan SW,Boyden ES,Brugge JS,Kaeser PS,Church GM,Agasti SS,Jungmann R,Yin P
Published figure using alpha Tubulin monoclonal antibody (Product # MA1-80017) in Immunocytochemistry
Wed Oct 11 00:00:00 EDT 2017
Microtubule structures underlying the sarcoplasmic reticulum support peripheral coupling sites to regulate smooth muscle contractility.
Science signaling
Pritchard HAT,Gonzales AL,Pires PW,Drumm BT,Ko EA,Sanders KM,Hennig GW,Earley S
MA1-80017 was used in Immunocytochemistry to study the role of the cytoskeleton in maintaining peripheral coupling and associated Ca2+ signalling networks within native smooth muscle cells.
Tue Sep 19 00:00:00 EDT 2017
EB1 and EB3 regulate microtubule minus end organization and Golgi morphology.
The Journal of cell biology
Yang C,Wu J,de Heus C,Grigoriev I,Liv N,Yao Y,Smal I,Meijering E,Klumperman J,Qi RZ,Akhmanova A
MA1-80017 was used in Immunocytochemistry-immunoflourescence to reveal the importance of EB1 and EB3 in affecting multiple aspects of interphase processes in mamalian cells. Notably, the control and organization of microtubule minus ends, and their interaction with the Golgi membrane.
Mon Oct 02 00:00:00 EDT 2017
Kinesin-4 KIF21B is a potent microtubule pausing factor.
eLife
van Riel WE,Rai A,Bianchi S,Katrukha EA,Liu Q,Heck AJ,Hoogenraad CC,Steinmetz MO,Kapitein LC,Akhmanova A
MA180017 was used in immunocytochemistry to investigate the impact of kinesin-4 KIF21B to microtubule pausing
Tue Mar 14 00:00:00 EDT 2017
Kinesin-4 KIF21B is a potent microtubule pausing factor.
eLife
van Riel WE,Rai A,Bianchi S,Katrukha EA,Liu Q,Heck AJ,Hoogenraad CC,Steinmetz MO,Kapitein LC,Akhmanova A
MA180017 was used in immunocytochemistry to investigate the impact of kinesin-4 KIF21B to microtubule pausing
Tue Mar 14 00:00:00 EDT 2017
Super-resolution microscopy with DNA-PAINT.
Nature protocols
Schnitzbauer J,Strauss MT,Schlichthaerle T,Schueder F,Jungmann R
MA1-80017 was used in ELISA, Immunocytochemistry, Immunohistochemistry (Frozen), Immunoprecipitation, Radioimmune assays, Western Blot to provide a n integrated software package, named Picasso, for the computational steps involved.
Thu Jun 01 00:00:00 EDT 2017
Expansion microscopy with conventional antibodies and fluorescent proteins.
Nature methods
Chozinski TJ,Halpern AR,Okawa H,Kim HJ,Tremel GJ,Wong RO,Vaughan JC
MA1-80017 was used in immunocytochemistry to utilize expansion microscopy with fluorescent proteins and conventional antibodies
Wed Jun 01 00:00:00 EDT 2016
Chemical and mechanical stimuli act on common signal transduction and cytoskeletal networks.
Proceedings of the National Academy of Sciences of the United States of America
Artemenko Y,Axiotakis L,Borleis J,Iglesias PA,Devreotes PN
MA180017 was used in immunocytochemistry to elucidate how mechanical stimuli activate signal transduction networks that govern cytoskeletal activity and cell migration
Tue Nov 22 00:00:00 EST 2016
Novel role for the midbody in primary ciliogenesis by polarized epithelial cells.
The Journal of cell biology
Bernabé-Rubio M,Andrés G,Casares-Arias J,Fernández-Barrera J,Rangel L,Reglero-Real N,Gershlick DC,Fernández JJ,Millán J,Correas I,Miguez DG,Alonso MA
Published figure using alpha Tubulin monoclonal antibody (Product # MA1-80017) in Immunofluorescence
Mon Aug 01 00:00:00 EDT 2016
Smoothened determines β-arrestin-mediated removal of the G protein-coupled receptor Gpr161 from the primary cilium.
The Journal of cell biology
Pal K,Hwang SH,Somatilaka B,Badgandi H,Jackson PK,DeFea K,Mukhopadhyay S
MA1-80017 was used in western blot to analyze beta-arrestin-mediated removal of the G protein-coupled receptor Gpr161 from the primary cilium determined by Smoothened
Mon Mar 28 00:00:00 EDT 2016
Expansion of Bone Marrow Adipose Tissue During Caloric Restriction Is Associated With Increased Circulating Glucocorticoids and Not With Hypoleptinemia.
Endocrinology
Cawthorn WP,Scheller EL,Parlee SD,Pham HA,Learman BS,Redshaw CM,Sulston RJ,Burr AA,Das AK,Simon BR,Mori H,Bree AJ,Schell B,Krishnan V,MacDougald OA
MA1-80017 was used in western blot to test if caloric restriction affects adiponectin production by bone marrow adipose tissue
Mon Feb 01 00:00:00 EST 2016
Expansion of Bone Marrow Adipose Tissue During Caloric Restriction Is Associated With Increased Circulating Glucocorticoids and Not With Hypoleptinemia.
Endocrinology
Cawthorn WP,Scheller EL,Parlee SD,Pham HA,Learman BS,Redshaw CM,Sulston RJ,Burr AA,Das AK,Simon BR,Mori H,Bree AJ,Schell B,Krishnan V,MacDougald OA
MA1-80017 was used in western blot to test if caloric restriction affects adiponectin production by bone marrow adipose tissue
Mon Feb 01 00:00:00 EST 2016
MICAL3 Flavoprotein Monooxygenase Forms a Complex with Centralspindlin and Regulates Cytokinesis.
The Journal of biological chemistry
Liu Q,Liu F,Yu KL,Tas R,Grigoriev I,Remmelzwaal S,Serra-Marques A,Kapitein LC,Heck AJ,Akhmanova A
Published figure using alpha Tubulin monoclonal antibody (Product # MA1-80017) in Immunocytochemistry
Fri Sep 23 00:00:00 EDT 2016
MICAL3 Flavoprotein Monooxygenase Forms a Complex with Centralspindlin and Regulates Cytokinesis.
The Journal of biological chemistry
Liu Q,Liu F,Yu KL,Tas R,Grigoriev I,Remmelzwaal S,Serra-Marques A,Kapitein LC,Heck AJ,Akhmanova A
Published figure using alpha Tubulin monoclonal antibody (Product # MA1-80017) in Immunocytochemistry
Fri Sep 23 00:00:00 EDT 2016
p120-catenin prevents multinucleation through control of MKLP1-dependent RhoA activity during cytokinesis.
Nature communications
van de Ven RA,de Groot JS,Park D,van Domselaar R,de Jong D,Szuhai K,van der Wall E,Rueda OM,Ali HR,Caldas C,van Diest PJ,Hetzer MW,Sahai E,Derksen PW
MA180017 was used in immunocytochemistry to discover p120-catenin both controls cell-cell adhesion and acts as a critical regulator of cytokinesis
Thu Dec 22 00:00:00 EST 2016
The MAL protein is crucial for proper membrane condensation at the ciliary base, which is required for primary cilium elongation.
Journal of cell science
Reales E,Bernabé-Rubio M,Casares-Arias J,Rentero C,Fernández-Barrera J,Rangel L,Correas I,Enrich C,Andrés G,Alonso MA
MA1-80017 was used in immunocytochemistry to study the role of MAL, a tetraspanning protein, in primary cilium formation
Mon Jun 15 00:00:00 EDT 2015
Bone marrow adipose tissue is an endocrine organ that contributes to increased circulating adiponectin during caloric restriction.
Cell metabolism
Cawthorn WP,Scheller EL,Learman BS,Parlee SD,Simon BR,Mori H,Ning X,Bree AJ,Schell B,Broome DT,Soliman SS,DelProposto JL,Lumeng CN,Mitra A,Pandit SV,Gallagher KA,Miller JD,Krishnan V,Hui SK,Bredella MA,Fazeli PK,Klibanski A,Horowitz MC,Rosen CJ,MacDougald OA
Published figure using alpha Tubulin monoclonal antibody (Product # MA1-80017) in Western Blot
Tue Aug 05 00:00:00 EDT 2014
Microtubule minus-end stabilization by polymerization-driven CAMSAP deposition.
Developmental cell
Jiang K,Hua S,Mohan R,Grigoriev I,Yau KW,Liu Q,Katrukha EA,Altelaar AF,Heck AJ,Hoogenraad CC,Akhmanova A
MA1-80017 was used in Immunocytochemistry to indicate that microtubule minus-end assembly drives the stabilization of noncentrosomal microtubules and that katanin regulates this process.
Mon Feb 10 00:00:00 EST 2014
Control of food intake and energy expenditure by Nos1 neurons of the paraventricular hypothalamus.
The Journal of neuroscience : the official journal of the Society for Neuroscience
Sutton AK,Pei H,Burnett KH,Myers MG,Rhodes CJ,Olson DP
Published figure using alpha Tubulin monoclonal antibody (Product # MA1-80017) in Western Blot
Wed Nov 12 00:00:00 EST 2014
Wnt6, Wnt10a and Wnt10b inhibit adipogenesis and stimulate osteoblastogenesis through a β-catenin-dependent mechanism.
Bone
Cawthorn WP,Bree AJ,Yao Y,Du B,Hemati N,Martinez-Santibañez G,MacDougald OA
Published figure using alpha Tubulin monoclonal antibody (Product # MA1-80017) in Western Blot
Wed Feb 01 00:00:00 EST 2012
Human 76p: A new member of the gamma-tubulin-associated protein family.
The Journal of cell biology
Fava F,Raynaud-Messina B,Leung-Tack J,Mazzolini L,Li M,Guillemot JC,Cachot D,Tollon Y,Ferrara P,Wright M
MA1-80017 was used in immunocytochemistry to investigate the role of the centrosomes in microtubule nucleation
Mon Nov 15 00:00:00 EST 1999
Indirect immunofluorescence of microtubules in Dictyostelium discoideum. A study with polyclonal and monoclonal antibodies to tubulins.
Experimental cell research
Roos UP,De Brabander M,De Mey J
MA1-80017 was used in immunocytochemistry to observe microtubule changes during the cell cycle of D. discoideum
Thu Mar 01 00:00:00 EST 1984
