Product References
Interferon-independent processes constrain measles virus cell-to-cell spread in primary human airway epithelial cells.
Microbiology spectrum
Durnell LA,Hippee CE,Cattaneo R,Bartlett JA,Singh BK,Sinn PL
Published figure using Vinculin recombinant monoclonal antibody (Product # 700062) in Western Blot
Tue Sep 19 00:00:00 EDT 2023
Piezo1 activates noncanonical EGFR endocytosis and signaling.
Science advances
Pardo-Pastor C,Rosenblatt J
Published figure using Vinculin recombinant monoclonal antibody (Product # 700062) in Western Blot
Fri Sep 29 00:00:00 EDT 2023
Ablation of Gabra5 Influences Corticosterone Levels and Anxiety-like Behavior in Mice.
Genes
Syding LA,Kubik-Zahorodna A,Reguera DP,Nickl P,Hruskova B,Kralikova M,Kopkanova J,Novosadova V,Kasparek P,Prochazka J,Rozman J,Turecek R,Sedlacek R
700062 was used in Western Blotting to investigate the relationship between the α5 subunit and corticosterone levels in a new mouse model deficient for Gabra5, which is known to be linked to anxiety disorders in humans and phenologs observed in mice.
Sat Jan 21 00:00:00 EST 2023
Ablation of Gabra5 Influences Corticosterone Levels and Anxiety-like Behavior in Mice.
Genes
Syding LA,Kubik-Zahorodna A,Reguera DP,Nickl P,Hruskova B,Kralikova M,Kopkanova J,Novosadova V,Kasparek P,Prochazka J,Rozman J,Turecek R,Sedlacek R
700062 was used in Western Blotting to investigate the relationship between the α5 subunit and corticosterone levels in a new mouse model deficient for Gabra5, which is known to be linked to anxiety disorders in humans and phenologs observed in mice.
Sat Jan 21 00:00:00 EST 2023
ULK1-mediated phosphorylation regulates the conserved role of YKT6 in autophagy.
Journal of cell science
Sánchez-Martín P,Kriegenburg F,Alves L,Adam J,Elsaesser J,Babic R,Mancilla H,Licheva M,Tascher G,Münch C,Eimer S,Kraft C
700062 was used in Western Blotting to reveal that timely regulation of the YKT6 phosphorylation status is crucial throughout autophagy progression and cell survival.
Wed Feb 01 00:00:00 EST 2023
α-Catenin links integrin adhesions to F-actin to regulate ECM mechanosensing and rigidity dependence.
The Journal of cell biology
Mukherjee A,Melamed S,Damouny-Khoury H,Amer M,Feld L,Nadjar-Boger E,Sheetz MP,Wolfenson H
Published figure using Vinculin recombinant monoclonal antibody (Product # 700062) in Immunoprecipitation
Mon Aug 01 00:00:00 EDT 2022
Increased Stiffness Downregulates Focal Adhesion Kinase Expression in Pancreatic Cancer Cells Cultured in 3D Self-Assembling Peptide Scaffolds.
Biomedicines
Betriu N,Andreeva A,Alonso A,Semino CE
700062 was used in Immunocytochemistry and Western Blotting to highlight how cell response to increased matrix stiffness greatly depends on the nature of the matrix used for 3D culture.
Fri Jul 29 00:00:00 EDT 2022
Increased Stiffness Downregulates Focal Adhesion Kinase Expression in Pancreatic Cancer Cells Cultured in 3D Self-Assembling Peptide Scaffolds.
Biomedicines
Betriu N,Andreeva A,Alonso A,Semino CE
700062 was used in Immunocytochemistry and Western Blotting to highlight how cell response to increased matrix stiffness greatly depends on the nature of the matrix used for 3D culture.
Fri Jul 29 00:00:00 EDT 2022
Increased Stiffness Downregulates Focal Adhesion Kinase Expression in Pancreatic Cancer Cells Cultured in 3D Self-Assembling Peptide Scaffolds.
Biomedicines
Betriu N,Andreeva A,Alonso A,Semino CE
700062 was used in Immunocytochemistry and Western Blotting to highlight how cell response to increased matrix stiffness greatly depends on the nature of the matrix used for 3D culture.
Fri Jul 29 00:00:00 EDT 2022
Nuclear tension controls mitotic entry by regulating cyclin B1 nuclear translocation.
The Journal of cell biology
Dantas M,Oliveira A,Aguiar P,Maiato H,Ferreira JG
700062 was used in Western Blotting to demonstrate how nuclear tension during the G2-M transition contributes to timely and efficient mitotic spindle assembly and prevents chromosomal instability.
Mon Dec 05 00:00:00 EST 2022
Nuclear tension controls mitotic entry by regulating cyclin B1 nuclear translocation.
The Journal of cell biology
Dantas M,Oliveira A,Aguiar P,Maiato H,Ferreira JG
700062 was used in Western Blotting to demonstrate how nuclear tension during the G2-M transition contributes to timely and efficient mitotic spindle assembly and prevents chromosomal instability.
Mon Dec 05 00:00:00 EST 2022
Augmin-dependent microtubule self-organization drives kinetochore fiber maturation in mammals.
Cell reports
Almeida AC,Soares-de-Oliveira J,Drpic D,Cheeseman LP,Damas J,Lewin HA,Larkin DM,Aguiar P,Pereira AJ,Maiato H
700062 was used in Western Blotting to underscore the contribution of augmin-mediated microtubule amplification for k-fiber self-organization and maturation in mammals.
Tue Apr 05 00:00:00 EDT 2022
ATRX loss in glioma results in dysregulation of cell-cycle phase transition and ATM inhibitor radio-sensitization.
Cell reports
Qin T,Mullan B,Ravindran R,Messinger D,Siada R,Cummings JR,Harris M,Muruganand A,Pyaram K,Miklja Z,Reiber M,Garcia T,Tran D,Danussi C,Brosnan-Cashman J,Pratt D,Zhao X,Rehemtulla A,Sartor MA,Venneti S,Meeker AK,Huse JT,Morgan MA,Lowenstein PR,Castro MG,Yadav VN,Koschmann C
700062 was used in Western Blot to demonstrate that ATRX-deficient high-grade gliomas (HGGs) display Chk1-mediated dysregulation of cell-cycle phase transitions, which opens a window for therapies targeting this phenotype.
Tue Jan 11 00:00:00 EST 2022
ATRX loss in glioma results in dysregulation of cell-cycle phase transition and ATM inhibitor radio-sensitization.
Cell reports
Qin T,Mullan B,Ravindran R,Messinger D,Siada R,Cummings JR,Harris M,Muruganand A,Pyaram K,Miklja Z,Reiber M,Garcia T,Tran D,Danussi C,Brosnan-Cashman J,Pratt D,Zhao X,Rehemtulla A,Sartor MA,Venneti S,Meeker AK,Huse JT,Morgan MA,Lowenstein PR,Castro MG,Yadav VN,Koschmann C
700062 was used in Western Blot to demonstrate that ATRX-deficient high-grade gliomas (HGGs) display Chk1-mediated dysregulation of cell-cycle phase transitions, which opens a window for therapies targeting this phenotype.
Tue Jan 11 00:00:00 EST 2022
A conserved domain of Drosophila RNA-binding protein Pumilio interacts with multiple CCR4-NOT deadenylase complex subunits to repress target mRNAs.
The Journal of biological chemistry
Haugen RJ,Arvola RM,Connacher RP,Roden RT,Goldstrohm AC
700062 was used in Western Blotting to identify the motifs that are necessary and sufficient for the activity of the third repression domain of Pumilio, designated RD3, which is present in all isoforms and has conserved regulatory function.
Thu Sep 01 00:00:00 EDT 2022
Wwox Binding to the Murine Brca1-BRCT Domain Regulates Timing of Brip1 and CtIP Phospho-Protein Interactions with This Domain at DNA Double-Strand Breaks, and Repair Pathway Choice.
International journal of molecular sciences
Park D,Gharghabi M,Reczek CR,Plow R,Yungvirt C,Aldaz CM,Huebner K
700062 was used in Western Blotting to show that murine Wwox does not bind Brca1 near the conserved mouse Brca1 phospho-S971 site, leaving it open for Chk2 phosphorylation and Brca1 activation.
Mon Mar 28 00:00:00 EDT 2022
Distinct genetic pathways define pre-malignant versus compensatory clonal hematopoiesis in Shwachman-Diamond syndrome.
Nature communications
Kennedy AL,Myers KC,Bowman J,Gibson CJ,Camarda ND,Furutani E,Muscato GM,Klein RH,Ballotti K,Liu S,Harris CE,Galvin A,Malsch M,Dale D,Gansner JM,Nakano TA,Bertuch A,Vlachos A,Lipton JM,Castillo P,Connelly J,Churpek J,Edwards JR,Hijiya N,Ho RH,Hofmann I,Huang JN,Keel S,Lamble A,Lau BW,Norkin M,Stieglitz E,Stock W,Walkovich K,Boettcher S,Brendel C,Fleming MD,Davies SM,Weller EA,Bahl C,Carter SL,Shimamura A,Lindsley RC
Published figure using Vinculin recombinant monoclonal antibody (Product # 700062) in Western Blot
Fri Feb 26 00:00:00 EST 2021
STIM1 Controls the Focal Adhesion Dynamics and Cell Migration by Regulating SOCE in Osteosarcoma.
International journal of molecular sciences
Lin YS,Lin YH,Nguyen Thi M,Hsiao SC,Chiu WT
700062 was used in Immunocytochemistry to explore the impact of stromal interaction molecule 1 (STIM1) mediated store-operated Ca2+ entry on the turnover of focal adhesion and cell migration.
Thu Dec 23 00:00:00 EST 2021
STIM1 Controls the Focal Adhesion Dynamics and Cell Migration by Regulating SOCE in Osteosarcoma.
International journal of molecular sciences
Lin YS,Lin YH,Nguyen Thi M,Hsiao SC,Chiu WT
700062 was used in Immunocytochemistry to explore the impact of stromal interaction molecule 1 (STIM1) mediated store-operated Ca2+ entry on the turnover of focal adhesion and cell migration.
Thu Dec 23 00:00:00 EST 2021
Transcriptional Regulation of PIK3CD and PIKFYVE in T-Cell Acute Lymphoblastic Leukemia by IKAROS and Protein Kinase CK2.
International journal of molecular sciences
Dovat E,Song C,Hu T,Rahman MA,Dhanyamraju PK,Klink M,Bogush D,Soliman M,Kane S,McGrath M,Ding Y,Desai D,Sharma A,Gowda C
700062 was used in Western Blot to demonstrate for the first time that in T-ALL, CK2 hyperactivity contributes to PI3K signaling pathway upregulation, at least in part, through impaired IKAROS transcriptional regulation of PIK3CD and PIKFYVE.
Fri Jan 15 00:00:00 EST 2021
Transcriptional Regulation of PIK3CD and PIKFYVE in T-Cell Acute Lymphoblastic Leukemia by IKAROS and Protein Kinase CK2.
International journal of molecular sciences
Dovat E,Song C,Hu T,Rahman MA,Dhanyamraju PK,Klink M,Bogush D,Soliman M,Kane S,McGrath M,Ding Y,Desai D,Sharma A,Gowda C
700062 was used in Western Blot to demonstrate for the first time that in T-ALL, CK2 hyperactivity contributes to PI3K signaling pathway upregulation, at least in part, through impaired IKAROS transcriptional regulation of PIK3CD and PIKFYVE.
Fri Jan 15 00:00:00 EST 2021
The Plasma Membrane Ca2+ Pump PMCA4b Regulates Melanoma Cell Migration through Remodeling of the Actin Cytoskeleton.
Cancers
Naffa R,Padányi R,Ignácz A,Hegyi Z,Jezsó B,Tóth S,Varga K,Homolya L,Hegedűs L,Schlett K,Enyedi A
700062 was used in Immunocytochemistry and Western Blotting to suggest that PMCA4b plays a critical role in adopting front-to-rear polarity in a normally spindle-shaped cell type through F-actin rearrangement resulting in a less aggressive melanoma cell phenotype.
Wed Mar 17 00:00:00 EDT 2021
The Plasma Membrane Ca2+ Pump PMCA4b Regulates Melanoma Cell Migration through Remodeling of the Actin Cytoskeleton.
Cancers
Naffa R,Padányi R,Ignácz A,Hegyi Z,Jezsó B,Tóth S,Varga K,Homolya L,Hegedűs L,Schlett K,Enyedi A
700062 was used in Immunocytochemistry and Western Blotting to suggest that PMCA4b plays a critical role in adopting front-to-rear polarity in a normally spindle-shaped cell type through F-actin rearrangement resulting in a less aggressive melanoma cell phenotype.
Wed Mar 17 00:00:00 EDT 2021
The Plasma Membrane Ca2+ Pump PMCA4b Regulates Melanoma Cell Migration through Remodeling of the Actin Cytoskeleton.
Cancers
Naffa R,Padányi R,Ignácz A,Hegyi Z,Jezsó B,Tóth S,Varga K,Homolya L,Hegedűs L,Schlett K,Enyedi A
700062 was used in Immunocytochemistry and Western Blotting to suggest that PMCA4b plays a critical role in adopting front-to-rear polarity in a normally spindle-shaped cell type through F-actin rearrangement resulting in a less aggressive melanoma cell phenotype.
Wed Mar 17 00:00:00 EDT 2021
The Plasma Membrane Ca2+ Pump PMCA4b Regulates Melanoma Cell Migration through Remodeling of the Actin Cytoskeleton.
Cancers
Naffa R,Padányi R,Ignácz A,Hegyi Z,Jezsó B,Tóth S,Varga K,Homolya L,Hegedűs L,Schlett K,Enyedi A
700062 was used in Immunocytochemistry and Western Blotting to suggest that PMCA4b plays a critical role in adopting front-to-rear polarity in a normally spindle-shaped cell type through F-actin rearrangement resulting in a less aggressive melanoma cell phenotype.
Wed Mar 17 00:00:00 EDT 2021
ARPC1B binds WASP to control actin polymerization and curtail tonic signaling in B cells.
JCI insight
Leung G,Zhou Y,Ostrowski P,Mylvaganam S,Boroumand P,Mulder DJ,Guo C,Muise AM,Freeman SA
700062 was used in Immunocytochemistry to conclude that ARPC1B is critical for ARP2/3 complexes to control steady-state signaling of immune cells.
Wed Dec 08 00:00:00 EST 2021
ARPC1B binds WASP to control actin polymerization and curtail tonic signaling in B cells.
JCI insight
Leung G,Zhou Y,Ostrowski P,Mylvaganam S,Boroumand P,Mulder DJ,Guo C,Muise AM,Freeman SA
700062 was used in Immunocytochemistry to conclude that ARPC1B is critical for ARP2/3 complexes to control steady-state signaling of immune cells.
Wed Dec 08 00:00:00 EST 2021
Transthyretin Promotes Axon Growth via Regulation of Microtubule Dynamics and Tubulin Acetylation.
Frontiers in cell and developmental biology
Eira J,Magalhães J,Macedo N,Pero ME,Misgeld T,Sousa MM,Bartolini F,Liz MA
700062 was used in Western Blotting to investigated whether TTR promotes axon elongation by modulating MT dynamics using mice models.
Tue Nov 30 00:00:00 EST 2021
Cardiac pericytes function as key vasoactive cells to regulate homeostasis and disease.
FEBS open bio
Lee LL,Khakoo AY,Chintalgattu V
700062 was used in Western Blotting to characterize cardiac PCs under in vitro disease conditions and supports the hypothesis that cardiac PCs are key vasoactive cells that can regulate blood flow in the heart.
Fri Jan 01 00:00:00 EST 2021
Poly(ADP-ribose) Glycohydrolase Inhibition Sequesters NAD+ to Potentiate the Metabolic Lethality of Alkylating Chemotherapy in IDH-Mutant Tumor Cells.
Cancer discovery
Nagashima H,Lee CK,Tateishi K,Higuchi F,Subramanian M,Rafferty S,Melamed L,Miller JJ,Wakimoto H,Cahill DP
700062 was used in Western Blotting to find that, in endogenous IDH1-mutant tumor models, alkylator-induced cytotoxicity is markedly augmented by pharmacologic inhibition or genetic knockout of the PAR breakdown enzyme PAR glycohydrolase (PARG).
Sun Nov 01 00:00:00 EDT 2020
A tumor-intrinsic PD-L1/NLRP3 inflammasome signaling pathway drives resistance to anti-PD-1 immunotherapy.
The Journal of clinical investigation
Theivanthiran B,Evans KS,DeVito NC,Plebanek M,Sturdivant M,Wachsmuth LP,Salama AK,Kang Y,Hsu D,Balko JM,Johnson DB,Starr M,Nixon AB,Holtzhausen A,Hanks BA
700062 was used in Western Blotting to identify a mechanism whereby CD8+ T cell activation in response to programmed cell death 1 (PD-1) blockade induced a programmed death ligand 1/NOD-, LRR-, and pyrin domain-containing protein 3 (PD-L1/NLRP3) inflammasome signaling cascade that ultimately led to the recruitment of granulocytic myeloid-derived suppressor cells (PMN-MDSCs) into tumor tissues, thereby dampening the resulting antitumor immune response.
Fri May 01 00:00:00 EDT 2020
Increased talin-vinculin spatial proximities in livers in response to spotted fever group rickettsial and Ebola virus infections.
Laboratory investigation; a journal of technical methods and pathology
Liu Y,Xiao J,Zhang B,Shelite TR,Su Z,Chang Q,Judy B,Li X,Drelich A,Bei J,Zhou Y,Zheng J,Jin Y,Rossi SL,Tang SJ,Wakamiya M,Saito T,Ksiazek T,Kaphalia B,Gong B
700062 was used in Proximity Ligation Assay to demonstrate an increase of talin–vinculin spatial proximities in the livers of spotted fever Rickettsia australis or Ebola virus infected mice when compared with mock mice.
Sat Aug 01 00:00:00 EDT 2020
Senescent mesenchymal stem cells remodel extracellular matrix driving breast cancer cells to a more-invasive phenotype.
Journal of cell science
Ghosh D,Mejia Pena C,Quach N,Xuan B,Lee AH,Dawson MR
700062 was used in Immunocytochemistry-immunoflourescence to investigate senescence-associated biophysical changes in MSCs and how this influences cancer cell behavior in a 3D matrix interface model.
Thu Jan 23 00:00:00 EST 2020
Culture and Differentiation of Human Hair Follicle Dermal Papilla Cells in a Soft 3D Self-Assembling Peptide Scaffold.
Biomolecules
Betriu N,Jarrosson-Moral C,Semino CE
Published figure using Vinculin recombinant monoclonal antibody (Product # 700062) in Western Blot
Tue Apr 28 00:00:00 EDT 2020
Culture and Differentiation of Human Hair Follicle Dermal Papilla Cells in a Soft 3D Self-Assembling Peptide Scaffold.
Biomolecules
Betriu N,Jarrosson-Moral C,Semino CE
Published figure using Vinculin recombinant monoclonal antibody (Product # 700062) in Western Blot
Tue Apr 28 00:00:00 EDT 2020
Succinic Semialdehyde Dehydrogenase Deficiency: In Vitro and In Silico Characterization of a Novel Pathogenic Missense Variant and Analysis of the Mutational Spectrum of ALDH5A1.
International journal of molecular sciences
Brennenstuhl H,Didiasova M,Assmann B,Bertoldi M,Molla G,Jung-Klawitter S,Kuseyri Hübschmann O,Schröter J,Opladen T,Tikkanen R
700062 was used in Western Blotting to present a patient with a severe phenotype of SSADHD caused by a novel genetic variant c.728T > C that leads to an exchange of leucine to proline at residue 243, located within the highly conserved nicotinamide adenine dinucleotide (NAD)+ binding domain of SSADH.
Fri Nov 13 00:00:00 EST 2020
Succinic Semialdehyde Dehydrogenase Deficiency: In Vitro and In Silico Characterization of a Novel Pathogenic Missense Variant and Analysis of the Mutational Spectrum of ALDH5A1.
International journal of molecular sciences
Brennenstuhl H,Didiasova M,Assmann B,Bertoldi M,Molla G,Jung-Klawitter S,Kuseyri Hübschmann O,Schröter J,Opladen T,Tikkanen R
700062 was used in Western Blotting to present a patient with a severe phenotype of SSADHD caused by a novel genetic variant c.728T > C that leads to an exchange of leucine to proline at residue 243, located within the highly conserved nicotinamide adenine dinucleotide (NAD)+ binding domain of SSADH.
Fri Nov 13 00:00:00 EST 2020
A fluorescence-activatable reporter of flavivirus NS2B-NS3 protease activity enables live imaging of infection in single cells and viral plaques.
The Journal of biological chemistry
Arias-Arias JL,MacPherson DJ,Hill ME,Hardy JA,Mora-Rodríguez R
700062 was used in Western Blotting to report the construction of fluorescence-activatable sensors to detect the activities of flavivirus NS2B-NS3 serine proteases in living cells.
Fri Feb 21 00:00:00 EST 2020
The Effects of Syndecan on Osteoblastic Cell Adhesion Onto Nano-Zirconia Surface.
International journal of nanomedicine
Sun L,Hong G,Matsui H,Song YJ,Sasaki K
700062 was used in Immunocytochemistry to evaluate the effect of Syndecan (Sdc) on osteoblastic cell (MC3T3-E1) adhesion and proliferation onto zirconia materials.
Mon Oct 19 00:00:00 EDT 2020
The Effects of Syndecan on Osteoblastic Cell Adhesion Onto Nano-Zirconia Surface.
International journal of nanomedicine
Sun L,Hong G,Matsui H,Song YJ,Sasaki K
700062 was used in Immunocytochemistry to evaluate the effect of Syndecan (Sdc) on osteoblastic cell (MC3T3-E1) adhesion and proliferation onto zirconia materials.
Mon Oct 19 00:00:00 EDT 2020
IDH-mutant gliomas harbor fewer regulatory T cells in humans and mice.
Oncoimmunology
Richardson LG,Nieman LT,Stemmer-Rachamimov AO,Zheng XS,Stafford K,Nagashima H,Miller JJ,Kiyokawa J,Ting DT,Wakimoto H,Cahill DP,Choi BD,Curry WT
700062 was used in Western Blotting to investigate the association of Tregs with IDH mutations in human glioma and a murine IDH-mutant mouse model.
Thu Aug 20 00:00:00 EDT 2020
A divalent siRNA chemical scaffold for potent and sustained modulation of gene expression throughout the central nervous system.
Nature biotechnology
Alterman JF,Godinho BMDC,Hassler MR,Ferguson CM,Echeverria D,Sapp E,Haraszti RA,Coles AH,Conroy F,Miller R,Roux L,Yan P,Knox EG,Turanov AA,King RM,Gernoux G,Mueller C,Gray-Edwards HL,Moser RP,Bishop NC,Jaber SM,Gounis MJ,Sena-Esteves M,Pai AA,DiFiglia M,Aronin N,Khvorova A
700062 was used in Western Blot to show that this siRNA design may enable RNA interference-based gene silencing in the CNS for the treatment of neurological disorders.
Thu Aug 01 00:00:00 EDT 2019
Minute-scale persistence of a GPCR conformation state triggered by non-cognate G protein interactions primes signaling.
Nature communications
Gupte TM,Ritt M,Dysthe M,Malik RU,Sivaramakrishnan S
Published figure using Vinculin recombinant monoclonal antibody (Product # 700062) in Western Blot
Wed Oct 23 00:00:00 EDT 2019
Mechano-signalling, induced by fullerene C60 nanofilms, arrests the cell cycle in the G2/M phase and decreases proliferation of liver cancer cells.
International journal of nanomedicine
Sosnowska M,Kutwin M,Jaworski S,Strojny B,Wierzbicki M,Szczepaniak J,Łojkowski M,Święszkowski W,Bałaban J,Chwalibog A,Sawosz E
Published figure using Vinculin recombinant monoclonal antibody (Product # 700062) in Western Blot
Fri Nov 08 00:00:00 EST 2019
Delineating the role of cooperativity in the design of potent PROTACs for BTK.
Proceedings of the National Academy of Sciences of the United States of America
Zorba A,Nguyen C,Xu Y,Starr J,Borzilleri K,Smith J,Zhu H,Farley KA,Ding W,Schiemer J,Feng X,Chang JS,Uccello DP,Young JA,Garcia-Irrizary CN,Czabaniuk L,Schuff B,Oliver R,Montgomery J,Hayward MM,Coe J,Chen J,Niosi M,Luthra S,Shah JC,El-Kattan A,Qiu X,West GM,Noe MC,Shanmugasundaram V,Gilbert AM,Brown MF,Calabrese MF
700062 was used in Simple Western - Size to show that alleviation of steric clashes between BTK and CRBN by modulating PROTAC linker length within this chemical series allows potent BTK degradation in the absence of thermodynamic cooperativity.
Tue Jul 31 00:00:00 EDT 2018
16-Hydroxycleroda-3,13-dien-15,16-olide induces anoikis in human renal cell carcinoma cells: involvement of focal adhesion disassembly and signaling.
OncoTargets and therapy
Chen YC,Huang BM,Lee WC,Chen YC
700062 was used in Immunocytochemistry-immunoflourescence to investigate the regulatory mechanisms of clerodane diterpene, 16-hydroxycleroda-3,13-dien-15,16-olide-induced apoptosis in clear cell renal cell carcinoma cells.
Wed Mar 30 00:00:00 EDT 2022
16-Hydroxycleroda-3,13-dien-15,16-olide induces anoikis in human renal cell carcinoma cells: involvement of focal adhesion disassembly and signaling.
OncoTargets and therapy
Chen YC,Huang BM,Lee WC,Chen YC
700062 was used in Immunocytochemistry-immunoflourescence to investigate the regulatory mechanisms of clerodane diterpene, 16-hydroxycleroda-3,13-dien-15,16-olide-induced apoptosis in clear cell renal cell carcinoma cells.
Wed Mar 30 00:00:00 EDT 2022
Transition of responsive mechanosensitive elements from focal adhesions to adherens junctions on epithelial differentiation.
Molecular biology of the cell
Noethel B,Ramms L,Dreissen G,Hoffmann M,Springer R,Rübsam M,Ziegler WH,Niessen CM,Merkel R,Hoffmann B
700062 was used in Immunocytochemistry-immunoflourescence to identify a mechanosensitive transition from cell-matrix to cell-cell adhesions on formation of keratinocyte monolayers with vinculin and α-catenin as vital players.
Sat Sep 15 00:00:00 EDT 2018
Decellularized extracellular matrix of human umbilical vein endothelial cells promotes endothelial differentiation of stem cells from exfoliated deciduous teeth.
Journal of biomedical materials research. Part A
Gong T,Heng BC,Xu J,Zhu S,Yuan C,Lo EC,Zhang C
700062 was used in immunocytochemistry to examine the unique characteristics of cell-specific extracellular matrix
Sat Apr 01 00:00:00 EDT 2017
Integrin-mediated traction force enhances paxillin molecular associations and adhesion dynamics that increase the invasiveness of tumor cells into a three-dimensional extracellular matrix.
Molecular biology of the cell
Mekhdjian AH,Kai F,Rubashkin MG,Prahl LS,Przybyla LM,McGregor AL,Bell ES,Barnes JM,DuFort CC,Ou G,Chang AC,Cassereau L,Tan SJ,Pickup MW,Lakins JN,Ye X,Davidson MW,Lammerding J,Odde DJ,Dunn AR,Weaver VM
Thu Jun 01 00:00:00 EDT 2017
Diamond, graphite, and graphene oxide nanoparticles decrease migration and invasiveness in glioblastoma cell lines by impairing extracellular adhesion.
International journal of nanomedicine
Wierzbicki M,Jaworski S,Kutwin M,Grodzik M,Strojny B,Kurantowicz N,Zdunek K,Chodun R,Chwalibog A,Sawosz E
Published figure using Vinculin monoclonal antibody (Product # 700062) in Western Blot
Fri Jan 26 00:00:00 EST 2018
Biosynthetic PCL-graft-Collagen Bulk Material for Tissue Engineering Applications.
Materials (Basel, Switzerland)
Gentile P,McColgan-Bannon K,Gianone NC,Sefat F,Dalgarno K,Ferreira AM
700062 was used in Immunocytochemistry-immunoflourescence to report the synthesis of a poly(ε-caprolactone)-graft-collagen copolymer.
Fri Jun 23 00:00:00 EDT 2017
Human snoRNA-93 is processed into a microRNA-like RNA that promotes breast cancer cell invasion.
NPJ breast cancer
Patterson DG,Roberts JT,King VM,Houserova D,Barnhill EC,Crucello A,Polska CJ,Brantley LW,Kaufman GC,Nguyen M,Santana MW,Schiller IA,Spicciani JS,Zapata AK,Miller MM,Sherman TD,Ma R,Zhao H,Arora R,Coley AB,Zeidan MM,Tan M,Xi Y,Borchert GM
700062 was used in Western Blotting to indicate that sdRNA-93 expression actively contributes to the malignant phenotype of breast cancer through participating in microRNA-like regulation.
Sat Aug 05 00:00:00 EDT 2023
Angiotensin receptors and β-catenin regulate brain endothelial integrity in malaria.
The Journal of clinical investigation
Gallego-Delgado J,Basu-Roy U,Ty M,Alique M,Fernandez-Arias C,Movila A,Gomes P,Weinstock A,Xu W,Edagha I,Wassmer SC,Walther T,Ruiz-Ortega M,Rodriguez A
Mon Oct 03 00:00:00 EDT 2016
Effects of decellularized matrices derived from periodontal ligament stem cells and SHED on the adhesion, proliferation and osteogenic differentiation of human dental pulp stem cells in vitro.
Tissue & cell
Heng BC,Zhu S,Xu J,Yuan C,Gong T,Zhang C
700062 was used in immunocytochemistry to characterize the effects of decellularized matrices derived from SHED and periodontal ligament stem cells on proliferation, adhesion and osteogenic differentiation of human dental pulp stem cells in vitro
Fri Apr 01 00:00:00 EDT 2016
Human fibroblasts display a differential focal adhesion phenotype relative to chimpanzee.
Evolution, medicine, and public health
Advani AS,Chen AY,Babbitt CC
700062 was used in immunocytochemistry to compare human and chimpanzee fibroblasts
Thu Mar 24 00:00:00 EDT 2016
Susceptibility to tuberculosis is associated with variants in the ASAP1 gene encoding a regulator of dendritic cell migration.
Nature genetics
Curtis J,Luo Y,Zenner HL,Cuchet-Lourenço D,Wu C,Lo K,Maes M,Alisaac A,Stebbings E,Liu JZ,Kopanitsa L,Ignatyeva O,Balabanova Y,Nikolayevskyy V,Baessmann I,Thye T,Meyer CG,Nürnberg P,Horstmann RD,Drobniewski F,Plagnol V,Barrett JC,Nejentsev S
Published figure using Vinculin monoclonal antibody (Product # 700062) in Immunofluorescence
Fri May 01 00:00:00 EDT 2015
Connectivity Map-based discovery of parbendazole reveals targetable human osteogenic pathway.
Proceedings of the National Academy of Sciences of the United States of America
Brum AM,van de Peppel J,van der Leije CS,Schreuders-Koedam M,Eijken M,van der Eerden BC,van Leeuwen JP
700062 was used in immunocytochemistry to identify pathways that stimulate osteoblast differentiation from human mesenchymal stromal cells
Tue Oct 13 00:00:00 EDT 2015
A multi-omics approach identifies key hubs associated with cell type-specific responses of airway epithelial cells to staphylococcal alpha-toxin.
PloS one
Richter E,Harms M,Ventz K,Gierok P,Chilukoti RK,Hildebrandt JP,Mostertz J,Hochgräfe F
Published figure using Vinculin monoclonal antibody (Product # 700062) in Immunofluorescence
Tue Feb 23 00:00:00 EST 2016
Force engages vinculin and promotes tumor progression by enhancing PI3K activation of phosphatidylinositol (3,4,5)-triphosphate.
Cancer research
Rubashkin MG,Cassereau L,Bainer R,DuFort CC,Yui Y,Ou G,Paszek MJ,Davidson MW,Chen YY,Weaver VM
700062 was used in immunocytochemistry to study the mechanism of the activation of focal adhesion protein vinculin by mechanical stress
Mon Sep 01 00:00:00 EDT 2014
Force engages vinculin and promotes tumor progression by enhancing PI3K activation of phosphatidylinositol (3,4,5)-triphosphate.
Cancer research
Rubashkin MG,Cassereau L,Bainer R,DuFort CC,Yui Y,Ou G,Paszek MJ,Davidson MW,Chen YY,Weaver VM
700062 was used in immunocytochemistry to study the mechanism of the activation of focal adhesion protein vinculin by mechanical stress
Mon Sep 01 00:00:00 EDT 2014
Dual-objective STORM reveals three-dimensional filament organization in the actin cytoskeleton.
Nature methods
Xu K,Babcock HP,Zhuang X
700062 was used in immunocytochemistry to develop an astigmatism imaging/dual objective STORM system for biological imaging using the actin cytoskeleton as a model system
Sun Jan 08 00:00:00 EST 2012
