Product References
Orai1 calcium channel inhibition prevents progression of chronic pancreatitis.
JCI insight
Szabó V,Csákány-Papp N,Görög M,Madácsy T,Varga Á,Kiss A,Tél B,Jójárt B,Crul T,Dudás K,Bagyánszki M,Bódi N,Ayaydin F,Jee S,Tiszlavicz L,Stauderman KA,Hebbar S,Pallagi P,Maléth J
MA3-745 was used in Immunohistochemistry-immunofluorescence to suggest that the overactivation of Orai1 is a crucial pathogenetic event in the progression of early CP and that inhibition of Orai1 could prevent the development of end-stage CP.
Mon Jul 10 00:00:00 EDT 2023
Multi-Targeting Approach in Glioblastoma Using Computer-Assisted Drug Discovery Tools to Overcome the Blood-Brain Barrier and Target EGFR/PI3Kp110β Signaling.
Cancers
Franco C,Kausar S,Silva MFB,Guedes RC,Falcao AO,Brito MA
Published figure using Vimentin monoclonal antibody (Product # MA3-745) in Immunocytochemistry
Tue Jul 19 00:00:00 EDT 2022
Nanoparticle endothelial delivery of PGC-1α attenuates hypoxia-induced pulmonary hypertension by attenuating EndoMT-caused vascular wall remodeling.
Redox biology
Cai D,Chen SY
Published figure using Vimentin monoclonal antibody (Product # MA3-745) in Immunohistochemistry
Thu Dec 01 00:00:00 EST 2022
Nanoparticle endothelial delivery of PGC-1α attenuates hypoxia-induced pulmonary hypertension by attenuating EndoMT-caused vascular wall remodeling.
Redox biology
Cai D,Chen SY
Published figure using Vimentin monoclonal antibody (Product # MA3-745) in Immunohistochemistry
Thu Dec 01 00:00:00 EST 2022
Soft, Dynamic Hydrogel Confinement Improves Kidney Organoid Lumen Morphology and Reduces Epithelial-Mesenchymal Transition in Culture.
Advanced science (Weinheim, Baden-Wurttemberg, Germany)
Ruiter FAA,Morgan FLC,Roumans N,Schumacher A,Slaats GG,Moroni L,LaPointe VLS,Baker MB
MA3-745 was used in Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot to show that engineering hydrogel mechanics and dynamics have a decided benefit for organoid culture.
Fri Jul 01 00:00:00 EDT 2022
Leflunomide Induces Dose-Dependent Lung Injury in Mice via Stimulating Vimentin and NLRP3 Inflammasome Production.
Frontiers in pharmacology
El-Sherbiny M,Atef H,Eladl MA,Mohamed AS,El-Shafey M,Ali HS,Zaitone SA,Alomar SY,Alqahtani SAM,Aloyouni SY,Attia MA
MA3-745 was used in Immunohistochemistry, Western Blot to examine the dose-dependent lung injury produced by leflunomide in healthy mice.
Tue May 18 00:00:00 EDT 2021
Leflunomide Induces Dose-Dependent Lung Injury in Mice via Stimulating Vimentin and NLRP3 Inflammasome Production.
Frontiers in pharmacology
El-Sherbiny M,Atef H,Eladl MA,Mohamed AS,El-Shafey M,Ali HS,Zaitone SA,Alomar SY,Alqahtani SAM,Aloyouni SY,Attia MA
MA3-745 was used in Immunohistochemistry, Western Blot to examine the dose-dependent lung injury produced by leflunomide in healthy mice.
Tue May 18 00:00:00 EDT 2021
Leflunomide Induces Dose-Dependent Lung Injury in Mice via Stimulating Vimentin and NLRP3 Inflammasome Production.
Frontiers in pharmacology
El-Sherbiny M,Atef H,Eladl MA,Mohamed AS,El-Shafey M,Ali HS,Zaitone SA,Alomar SY,Alqahtani SAM,Aloyouni SY,Attia MA
MA3-745 was used in Immunohistochemistry, Western Blot to examine the dose-dependent lung injury produced by leflunomide in healthy mice.
Tue May 18 00:00:00 EDT 2021
Myocyte Enhancer Factor 2C as a New Player in Human Breast Cancer Brain Metastases.
Cells
Galego S,Kauppila LA,Malhó R,Pimentel J,Brito MA
MA3-745 was used in Immunohistochemistry to ascertain MEF2C expression in human BCBM, establish the relationship with disease severity, disclose the involvement of vascular endothelial growth factor receptor-2 (VEGFR-2) and β-catenin, also known as KDR and CTNNB1, respectively, and investigate if matched primary tumors express the protein.
Fri Feb 12 00:00:00 EST 2021
Myocyte Enhancer Factor 2C as a New Player in Human Breast Cancer Brain Metastases.
Cells
Galego S,Kauppila LA,Malhó R,Pimentel J,Brito MA
MA3-745 was used in Immunohistochemistry to ascertain MEF2C expression in human BCBM, establish the relationship with disease severity, disclose the involvement of vascular endothelial growth factor receptor-2 (VEGFR-2) and β-catenin, also known as KDR and CTNNB1, respectively, and investigate if matched primary tumors express the protein.
Fri Feb 12 00:00:00 EST 2021
Targeting the Temporal Dynamics of Hypoxia-Induced Tumor-Secreted Factors Halts Tumor Migration.
Cancer research
Singh M,Tian XJ,Donnenberg VS,Watson AM,Zhang J,Stabile LP,Watkins SC,Xing J,Sant S
MA3-745 was used in Western Blotting to study temporal dynamics of tumor-secreted microenvironmental factors in inducing tumor migration.
Sat Jun 01 00:00:00 EDT 2019
Establishment and characterization of a novel cell line (cc‑006cpm8) of moderately/poorly differentiated colorectal adenocarcinoma derived from a primary tumor of a patient.
International journal of oncology
Chu X,Xue Y,Huo X,Wei J,Chen Y,Han R,Chen H,Su X,Zhang H,Gong Y,Chen J
MA3-745 was used in Immunohistochemistry to analyze commonly mutated genes in colorectal cancer and exon mutations of genes in cc-006cpm8 cells.
Mon Jul 01 00:00:00 EDT 2019
Antisense oligonucleotide therapy rescues aggresome formation in a novel spinocerebellar ataxia type 3 human embryonic stem cell line.
Stem cell research
Moore LR,Keller L,Bushart DD,Delatorre RG,Li D,McLoughlin HS,do Carmo Costa M,Shakkottai VG,Smith GD,Paulson HL
MA3-745 was used in Immunocytochemistry-immunoflourescence to present a novel hESC line that expresses the endogenous SCA3 human disease protein.
Thu Aug 01 00:00:00 EDT 2019
YBX-1 mediated sorting of miR-133 into hypoxia/reoxygenation-induced EPC-derived exosomes to increase fibroblast angiogenesis and MEndoT.
Stem cell research & therapy
Lin F,Zeng Z,Song Y,Li L,Wu Z,Zhang X,Li Z,Ke X,Hu X
Published figure using Vimentin monoclonal antibody (Product # MA3-745) in Western Blot
Fri Aug 23 00:00:00 EDT 2019
Oncogenic PKC-ι activates Vimentin during epithelial-mesenchymal transition in melanoma; a study based on PKC-ι and PKC-ζ specific inhibitors.
Cell adhesion & migration
Ratnayake WS,Apostolatos CA,Apostolatos AH,Schutte RJ,Huynh MA,Ostrov DA,Acevedo-Duncan M
Published figure using Vimentin monoclonal antibody (Product # MA3-745) in Immunocytochemistry
Mon Mar 09 00:00:00 EDT 2020
Oncogenic PKC-ι activates Vimentin during epithelial-mesenchymal transition in melanoma; a study based on PKC-ι and PKC-ζ specific inhibitors.
Cell adhesion & migration
Ratnayake WS,Apostolatos CA,Apostolatos AH,Schutte RJ,Huynh MA,Ostrov DA,Acevedo-Duncan M
Published figure using Vimentin monoclonal antibody (Product # MA3-745) in Immunocytochemistry
Mon Mar 09 00:00:00 EDT 2020
Two novel atypical PKC inhibitors; ACPD and DNDA effectively mitigate cell proliferation and epithelial to mesenchymal transition of metastatic melanoma while inducing apoptosis.
International journal of oncology
Ratnayake WS,Apostolatos AH,Ostrov DA,Acevedo-Duncan M
Wed Nov 01 00:00:00 EDT 2017
RhoC is essential in TGF-β1 induced epithelial-mesenchymal transition in cervical cancer cells.
Oncology letters
He X,Qian Y,Cai H,Yang S,Cai J,Wang Z
Published figure using Vimentin monoclonal antibody (Product # MA3-745) in Western Blot
Sat Aug 01 00:00:00 EDT 2015
RhoC is essential in TGF-β1 induced epithelial-mesenchymal transition in cervical cancer cells.
Oncology letters
He X,Qian Y,Cai H,Yang S,Cai J,Wang Z
Published figure using Vimentin monoclonal antibody (Product # MA3-745) in Western Blot
Sat Aug 01 00:00:00 EDT 2015
High-throughput subcellular protein localization using transfected-cell arrays. Subcellular protein localization using cell arrays.
Methods in molecular biology (Clifton, N.J.)
Hu Y,Janitz M
MA3-745 was used in In vitro experiments to facilitate the precise determination of the localizations of numerous recombinant proteins in a single experiment, making it currently the most efficient technique for high-throughput protein co-localization screening.
Tue Mar 22 00:00:00 EDT 2011
Genetic deletion of COX-2 diminishes VEGF production in mouse retinal Müller cells.
Experimental eye research
Yanni SE,McCollum GW,Penn JS
MA3-745 was used in immunocytochemistry to investigate the role of COX2 in vascular endothelial growth factor production in retinal Muller cells
Thu Jul 01 00:00:00 EDT 2010
Protein composition of plasminogen activator inhibitor type 1-derived endothelial microparticles.
Shock (Augusta, Ga.)
Sander TL,Ou JS,Densmore JC,Kaul S,Matus I,Twigger S,Halligan B,Greene AS,Pritchard KA,Oldham KT
MA3-745 was used in western blot to study the protein composition of endothelial microparticles obtained from human endothelial cells stimulated with PAI-1
Tue Apr 01 00:00:00 EDT 2008
Comparative proteomics profiling of a phospholamban mutant mouse model of dilated cardiomyopathy reveals progressive intracellular stress responses.
Molecular & cellular proteomics : MCP
Gramolini AO,Kislinger T,Alikhani-Koopaei R,Fong V,Thompson NJ,Isserlin R,Sharma P,Oudit GY,Trivieri MG,Fagan A,Kannan A,Higgins DG,Huedig H,Hess G,Arab S,Seidman JG,Seidman CE,Frey B,Perry M,Backx PH,Liu PP,MacLennan DH,Emili A
MA3-745 was used in western blot to perform the global proteomics surveys of cardiac ventricle of a phospholamban mutant mouse
Sat Mar 01 00:00:00 EST 2008
Isolation of lipid droplets from cells by density gradient centrifugation.
Current protocols in cell biology
Brasaemle DL,Wolins NE
MA3-745 was used in western blot to evaluate a density gradient centrifugation protocol for the isolation of cellular lipid droplets
Sun Jan 01 00:00:00 EST 2006
Shiga toxin binding to globotriaosyl ceramide induces intracellular signals that mediate cytoskeleton remodeling in human renal carcinoma-derived cells.
Journal of cell science
Takenouchi H,Kiyokawa N,Taguchi T,Matsui J,Katagiri YU,Okita H,Okuda K,Fujimoto J
MA3-745 was used in immunohistochemistry to investigate the role of lipid-raft-mediated cell signaling in cytoskeletal remodeling.
Sun Aug 01 00:00:00 EDT 2004