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SSEA-3 Antibody (606-270) in IHC (P)
Product Details
606-270
Species Reactivity
Host/Isotype
Class
Type
Clone
Immunogen
Conjugate
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Purification
Storage buffer
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Product Specific Information
Positive control: Human Embryonic Carcinoma Cells
Cellular location: Membrane.
Target Information
SSEA-3 (stage-specific embryonic antigen 3) is a cell surface antigen, expressed along with SSEA-4, TRA-1-60 and TRA-1-81 in embryonic stem cells, embryonal carcinoma cells, and induced pluripotent stem cells (iPS). In human cells, these surface markers are down-regulated during the differentiation process, while SSEA1 is absent in undifferentiated human stem cells and upregulated on the cell surface after retinoic acid mediated differentiation. Conversely, in mouse stem cells, SSEA-1 expression decreases with differentiation while SSEA-3 and SSEA-4 expression increase.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Bioinformatics
Protein Aliases: SSEA-3; stage-specific embryonic antigen 3
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