Invitrogen

SLC27A2 Polyclonal Antibody

View all (11) SLC27A2 antibodies
Datasheet
Protocols
Questions & Answers
Datasheet
Protocols
Questions & Answers

Product Details

PA5-102343

Applications
Tested Dilution
Publications

Western Blot (WB)

1:500-1:2,000
-

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:200
-

Immunocytochemistry (ICC/IF)

1:100-1:500
-
Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

A synthesized peptide derived from human SLC27A2(Accession O14975), corresponding to amino acid residues E61-M111.
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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Affinity chromatography

Storage buffer

PBS, pH 7.4, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice

RRID

AB_2851750

Product Specific Information

Antibody detects endogenous levels of total SLC27A2.

Target Information

The protein encoded by this gene is an isozyme of long-chain fatty-acid-coenzyme A ligase family. Although differing in substrate specificity, subcellular localization, and tissue distribution, all isozymes of this family convert free long-chain fatty acids into fatty acyl-CoA esters, and thereby play a key role in lipid biosynthesis and fatty acid degradation. This isozyme activates long-chain, branched-chain and very-long-chain fatty acids containing 22 or more carbons to their CoA derivatives. It is expressed primarily in liver and kidney, and is present in both endoplasmic reticulum and peroxisomes but not in mitochondria. Its decreased peroxisomal enzyme activity is in part responsible for the biochemical pathology in X-linked adrenoleukodystrophy.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: Arachidonate--CoA ligase; FATP-2; Fatty acid transport protein 2; Fatty-acid-coenzyme A ligase, very long-chain 1; Long-chain fatty acid transport protein 2; Long-chain-fatty-acid--CoA ligase; Phytanate--CoA ligase; Slc27a2; solute carrier family 27 (fatty acid transporter), member 2; solute carrier family 27 (fatty acid transporter), member 32; Solute carrier family 27 member 2; THCA-CoA ligase; ve; Very long-chain acyl-CoA synthetase; very long-chain acyl-Coenzyme A dehydrogenase synthase; very long-chain fatty-acid-coenzyme A ligase 1; Very long-chain-fatty-acid-CoA ligase; very-long-chain acyl-CoA synthetase; VLACS; VLCS

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Gene Aliases: ACSVL1; FACVL1; FATP2; hFACVL1; HsT17226; SLC27A2; Vlac; VLACS; VLCS

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UniProt ID: (Human) O14975, (Rat) P97524, (Mouse) O35488

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Entrez Gene ID: (Human) 11001, (Rat) 65192, (Mouse) 26458

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Function(s)
long-chain fatty acid-CoA ligase activity receptor binding ATP binding fatty acid transporter activity enzyme binding very long-chain fatty acid-CoA ligase activity phytanate-CoA ligase activity pristanate-CoA ligase activity decanoate--CoA ligase activity protein binding nucleotide binding catalytic activity acyl-CoA ligase activity succinate-CoA ligase activity 3-oxo-2-(2'-pentenyl)cyclopentane-1-octanoic acid CoA ligase activity fatty acid ligase activity ligase activity 3-isopropenyl-6-oxoheptanoyl-CoA synthetase activity 2-oxo-delta3-4,5,5-trimethylcyclopentenylacetyl-CoA synthetase activity benzoyl acetate-CoA ligase activity 2,4-dichlorobenzoate-CoA ligase activity pivalate-CoA ligase activity cyclopropanecarboxylate-CoA ligase activity adipate-CoA ligase activity citronellyl-CoA ligase activity mentha-1,3-dione-CoA ligase activity thiophene-2-carboxylate-CoA ligase activity 2,4,4-trimethylpentanoate-CoA ligase activity cis-2-methyl-5-isopropylhexa-2,5-dienoate-CoA ligase activity trans-2-methyl-5-isopropylhexa-2,5-dienoate-CoA ligase activity branched-chain acyl-CoA synthetase (ADP-forming) activity aryl-CoA synthetase (ADP-forming) activity 3-hydroxypropionyl-CoA synthetase activity perillic acid:CoA ligase (ADP-forming) activity perillic acid:CoA ligase (AMP-forming) activity (3R)-3-isopropenyl-6-oxoheptanoate:CoA ligase (ADP-forming) activity (3R)-3-isopropenyl-6-oxoheptanoate:CoA ligase (AMP-forming) activity malonyl-CoA synthetase activity transporter secondary carrier transporter
Process(es)
fatty acid alpha-oxidation long-chain fatty acid metabolic process fatty acid beta-oxidation bile acid biosynthetic process fatty acid transport very long-chain fatty acid catabolic process long-chain fatty acid import methyl-branched fatty acid metabolic process very long-chain fatty acid metabolic process lipid metabolic process fatty acid metabolic process metabolic process
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