Product References
Critical Role of Notch-1 in Mechanistic Target of Rapamycin Hyperactivity and Vascular Inflammation in Patients With Takayasu Arteritis.
Arthritis & rheumatology (Hoboken, N.J.)
Jiang W,Sun M,Wang Y,Zheng M,Yuan Z,Mai S,Zhang X,Tang L,Liu X,Wang C,Wen Z
42-4000 was used in Flow cytometry/Cell sorting to investigate Notch-1 and potential mechanisms involved in Takayasu arteritis.
Fri Jul 01 00:00:00 EDT 2022
Neuronal subtype-specific growth cone and soma purification from mammalian CNS via fractionation and fluorescent sorting for subcellular analyses and spatial mapping of local transcriptomes and proteomes.
Nature protocols
Engmann AK,Hatch JJ,Nanda P,Veeraraghavan P,Ozkan A,Poulopoulos A,Murphy AJ,Macklis JD
42-4000 was used in Western Blotting to isolate a pure population of GCs and paired somata from any neuronal subtype of the CNS that can be fluorescently labeled.
Tue Feb 01 00:00:00 EST 2022
The small GTPase Rab32 resides on lysosomes to regulate mTORC1 signaling.
Journal of cell science
Drizyte-Miller K,Chen J,Cao H,Schott MB,McNiven MA
42-4000 was used in Immunocytochemistry-Immunofluorescence to these findings suggest that Rab32 functions as a novel regulator of cellular metabolism through supporting mTORC1 signaling.
Thu Jun 11 00:00:00 EDT 2020
Targeting Mechanistic Target of Rapamycin Complex 1 Restricts Proinflammatory T Cell Differentiation and Ameliorates Takayasu Arteritis.
Arthritis & rheumatology (Hoboken, N.J.)
Zhang J,Zhao L,Wang J,Cheng Z,Sun M,Zhao J,Liu B,Liu X,Wen Z,Li Z
42-4000 was used in Flow cytometry/Cell sorting to explore the involvement of mechanistic target of rapamycin (mTOR) in proinflammatory T cell differentiation and disease progression in TAK.
Sat Feb 01 00:00:00 EST 2020
Subcellular transcriptomes and proteomes of developing axon projections in the cerebral cortex.
Nature
Poulopoulos A,Murphy AJ,Ozkan A,Davis P,Hatch J,Kirchner R,Macklis JD
42-4000 was used in Immunocytochemistry-immunoflourescence to illuminate the relationships between subcellular distributions of RNA and protein in developing projection neurons, and provide a systems-level approach for the discovery of subtype- and stage-specific molecular substrates of circuit wiring, miswiring, and the potential for regeneration.
Tue Jan 01 00:00:00 EST 2019
Subcellular transcriptomes and proteomes of developing axon projections in the cerebral cortex.
Nature
Poulopoulos A,Murphy AJ,Ozkan A,Davis P,Hatch J,Kirchner R,Macklis JD
42-4000 was used in Immunocytochemistry-immunoflourescence to illuminate the relationships between subcellular distributions of RNA and protein in developing projection neurons, and provide a systems-level approach for the discovery of subtype- and stage-specific molecular substrates of circuit wiring, miswiring, and the potential for regeneration.
Tue Jan 01 00:00:00 EST 2019
Subcellular transcriptomes and proteomes of developing axon projections in the cerebral cortex.
Nature
Poulopoulos A,Murphy AJ,Ozkan A,Davis P,Hatch J,Kirchner R,Macklis JD
42-4000 was used in Immunocytochemistry-immunoflourescence to illuminate the relationships between subcellular distributions of RNA and protein in developing projection neurons, and provide a systems-level approach for the discovery of subtype- and stage-specific molecular substrates of circuit wiring, miswiring, and the potential for regeneration.
Tue Jan 01 00:00:00 EST 2019
Subcellular transcriptomes and proteomes of developing axon projections in the cerebral cortex.
Nature
Poulopoulos A,Murphy AJ,Ozkan A,Davis P,Hatch J,Kirchner R,Macklis JD
42-4000 was used in Immunocytochemistry-immunoflourescence to illuminate the relationships between subcellular distributions of RNA and protein in developing projection neurons, and provide a systems-level approach for the discovery of subtype- and stage-specific molecular substrates of circuit wiring, miswiring, and the potential for regeneration.
Tue Jan 01 00:00:00 EST 2019
mTOR inhibitors lower an intrinsic barrier to virus infection mediated by IFITM3.
Proceedings of the National Academy of Sciences of the United States of America
Shi G,Ozog S,Torbett BE,Compton AA
42-4000 was used in Western Blotting to elucidate a functional convergence between the mammalian target of rapamycin pathway and interferon-induced transmembrane proteins at endolysosomal membranes.
Tue Oct 23 00:00:00 EDT 2018
Regulation of mTORC1 by lysosomal calcium and calmodulin.
eLife
Li RJ,Xu J,Fu C,Zhang J,Zheng YG,Jia H,Liu JO
42-4000 was used in Immunoprecipitation to report that proper lysosomal calcium release through the calcium channel TRPML1 is required for mTORC1 activation.
Thu Oct 27 00:00:00 EDT 2016
Regulation of mTORC1 by lysosomal calcium and calmodulin.
eLife
Li RJ,Xu J,Fu C,Zhang J,Zheng YG,Jia H,Liu JO
42-4000 was used in Immunoprecipitation to report that proper lysosomal calcium release through the calcium channel TRPML1 is required for mTORC1 activation.
Thu Oct 27 00:00:00 EDT 2016
Raptor is phosphorylated by cdc2 during mitosis.
PloS one
Gwinn DM,Asara JM,Shaw RJ
Fri Feb 12 00:00:00 EST 2010
Raptor is phosphorylated by cdc2 during mitosis.
PloS one
Gwinn DM,Asara JM,Shaw RJ
Fri Feb 12 00:00:00 EST 2010
Connexin 37 is localized in renal epithelia and responds to changes in dietary salt intake.
American journal of physiology. Renal physiology
Stoessel A,Himmerkus N,Bleich M,Bachmann S,Theilig F
Fri Jan 01 00:00:00 EST 2010
Connexin 37 is localized in renal epithelia and responds to changes in dietary salt intake.
American journal of physiology. Renal physiology
Stoessel A,Himmerkus N,Bleich M,Bachmann S,Theilig F
Fri Jan 01 00:00:00 EST 2010