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Invitrogen
RAP1A Monoclonal Antibody (5F8)
This Antibody was verified by Relative expression to ensure that the antibody binds to the antigen stated.
FIGURE: 1 / 5
RAP1A Antibody (MA5-17164) in WB
Product Details
MA5-17164
Species Reactivity
Host/Isotype
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Clone
Immunogen
Conjugate
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RRID
Product Specific Information
MA5-17164 targets RAP1A in FACS, indirect ELISA, and WB applications and shows reactivity with Human samples.
The MA5-17164 immunogen is purified recombinant fragment of human RAP1A expressed in E. Coli.
MA5-17164 detects RAP1A which has a predicted molecular weight of approximately 21kDa.
Target Information
The product of this gene belongs to the family of RAS-related proteins. These proteins share approximately 50% amino acid identity with the classical RAS proteins and have numerous structural features in common. The most striking difference between RAP proteins and RAS proteins resides in their 61st amino acid: glutamine in RAS is replaced by threonine in RAP proteins. The product of this gene counteracts the mitogenic function of RAS because it can interact with RAS GAPs and RAF in a competitive manner. Two transcript variants encoding the same protein have been identified for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Bioinformatics
Protein Aliases: C21KG; G-22K; GTP-binding protein smg p21A; Ras-related protein Krev-1; Ras-related protein Rap-1A
Gene Aliases: C21KG; G-22K; KREV-1; KREV1; RAP1; RAP1A; SMGP21
UniProt ID: (Human) P62834
Entrez Gene ID: (Human) 5906
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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