Product References
4-F-PCP, a Novel PCP Analog Ameliorates the Depressive-Like Behavior of Chronic Social Defeat Stress Mice via NMDA Receptor Antagonism.
Biomolecules & therapeutics
Ortiz DMD,Kim M,Lee HJ,Botanas CJ,Custodio RJP,Sayson LV,Campomayor NB,Lee C,Lee YS,Cheong JH,Kim HJ
44-680G was used in Immunohistochemistry (Paraffin), Western Blot to provide significant implications for future research not only with PCP analogs but also on the next generation of different types of antidepressants.
Wed Mar 01 00:00:00 EST 2023
Insights into cellular behavior and micromolecular communication in urothelial micrografts.
Scientific reports
Juul N,Willacy O,Mamand DR,Andaloussi SE,Eisfeldt J,Chamorro CI,Fossum M
44-680G was used in Immunohistochemistry to demonstrate that increased tissue fragmentation subsequently potentiated the yield of proliferative cells and the cellular expansion potential, which confirms, that the micrografting principles of skin epithelium also apply to uroepithelium.
Mon Aug 21 00:00:00 EDT 2023
Pinostrobin from Boesenbergia rotunda attenuates oxidative stress and promotes functional recovery in rat model of sciatic nerve crush injury.
Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas
Kongsui R,Surapinit S,Promsrisuk T,Thongrong S
44-680G was used in Immunohistochemistry-immunofluorescence to indicate that PB diminished the oxidative stress-induced nerve injury.
Thu Mar 02 00:00:00 EST 2023
Sialylation of TLR2 initiates osteoclast fusion.
Bone research
Dou C,Zhen G,Dan Y,Wan M,Limjunyawong N,Cao X
44-680G was used in Western Blot to reveal that cell recognition mediated by the binding of sialylated TLR2 to Siglec15 initiates cell fusion for osteoclast formation.
Wed Mar 02 00:00:00 EST 2022
Suppression of phosphodiesterase IV enzyme by roflumilast ameliorates cognitive dysfunction in aged rats after sevoflurane anaesthesia via PKA-CREB and MEK/ERK pathways.
The European journal of neuroscience
Liu P,Wang J,Peng S,Zhang D,Zhuang L,Liu C,Zhang Y,Shi X
44-680G was used in Immunohistochemistry (Paraffin), Western Blot to demonstrate that RF treatment promotes neuronal activity by maintaining cAMP levels and sustaining the activation of PKA-CREB and MEK/ERK pathways, offering novel insights for POCD therapy.
Mon Aug 01 00:00:00 EDT 2022
Inhibition of colon cancer K-RasG13D mutation reduces cancer cell proliferation but promotes stemness and inflammation via RAS/ERK pathway.
Frontiers in pharmacology
Qi Y,Zou H,Zhao X,Kapeleris J,Monteiro M,Li F,Xu ZP,Deng Y,Wu Y,Tang Y,Gu W
Published figure using Phospho-ERK1/ERK2 (Thr185, Tyr187) polyclonal antibody (Product # 44-680G) in Western Blot
Fri Nov 18 00:00:00 EST 2022
Inhibition of colon cancer K-RasG13D mutation reduces cancer cell proliferation but promotes stemness and inflammation via RAS/ERK pathway.
Frontiers in pharmacology
Qi Y,Zou H,Zhao X,Kapeleris J,Monteiro M,Li F,Xu ZP,Deng Y,Wu Y,Tang Y,Gu W
Published figure using Phospho-ERK1/ERK2 (Thr185, Tyr187) polyclonal antibody (Product # 44-680G) in Western Blot
Fri Nov 18 00:00:00 EST 2022
EphA3 targeted by miR-3666 contributes to melanoma malignancy via activating ERK1/2 and p38 MAPK pathways.
Open medicine (Warsaw, Poland)
Ming D,Ma J
44-680G was used in Immunohistochemistry (Paraffin), Western Blot to conclude that miR-3666 downregulated EphA3 expression and retarded melanoma malignancy via inactivating ERK1/2 and p38 MAPK pathways.
Tue Jan 03 00:00:00 EST 2023
The Synergistic Effect of Cyclic Tensile Force and Periodontal Ligament Cell-Laden Calcium Silicate/Gelatin Methacrylate Auxetic Hydrogel Scaffolds for Bone Regeneration.
Cells
Lee JJ,Ng HY,Lin YH,Lin TJ,Kao CT,Shie MY
44-680G was used in Western Blotting to show that novel auxetic scaffolds could be fabricated by combining different aspects of science and technology, in order to improve the future chances of clinical applications for bone regeneration.
Wed Jun 29 00:00:00 EDT 2022
Novel peanut-specific human IgE monoclonal antibodies enable screens for inhibitors of the effector phase in food allergy.
Frontiers in immunology
Suber J,Zhang Y,Ye P,Guo R,Burks AW,Kulis MD,Smith SA,Iweala OI
44-680G was used in Western Blotting to provide a unique screening tool to assess the efficacy of therapeutics that target allergy effector cells and inhibit food allergen-induced effector cell activation.
Tue Oct 18 00:00:00 EDT 2022
Andrographolide Relieves Post-Operative Wound Pain but Affects Local Angiogenesis.
Pharmaceuticals (Basel, Switzerland)
Lin YL,Liao JW,Wang S,Sridharan B,Lee HJ,Li A,Chang KM,Wu CY,Huang S,Chang KT,Agrawal DC,Chen CJ,Lee MJ
44-680G was used in Immunohistochemistry to explore the ability of Andro to reduce pain sensation in a rat post-operative wound model.
Mon Dec 19 00:00:00 EST 2022
Hematopoietic Cell Kinase (HCK) Is a Player of the Crosstalk Between Hematopoietic Cells and Bone Marrow Niche Through CXCL12/CXCR4 Axis.
Frontiers in cell and developmental biology
Roversi FM,Bueno MLP,Pericole FV,Saad STO
44-680G was used in Western Blot to study the role of one SFK member, the Hematopoietic Cell Kinase (HCK), in CXCL12/CXCR4 pathway and its contribution to the AML pathogenesis.
Tue Apr 13 00:00:00 EDT 2021
Leptin reduces in vitro cementoblast mineralization and survival as well as induces PGE2 release by ERK1/2 commitment.
Clinical oral investigations
Ruiz-Heiland G,Yong JW,von Bremen J,Ruf S
Published figure using Phospho-ERK1/ERK2 (Thr185, Tyr187) polyclonal antibody (Product # 44-680G) in Western Blot
Thu Apr 01 00:00:00 EDT 2021
Leptin reduces in vitro cementoblast mineralization and survival as well as induces PGE2 release by ERK1/2 commitment.
Clinical oral investigations
Ruiz-Heiland G,Yong JW,von Bremen J,Ruf S
Published figure using Phospho-ERK1/ERK2 (Thr185, Tyr187) polyclonal antibody (Product # 44-680G) in Western Blot
Thu Apr 01 00:00:00 EDT 2021
Response of human cancer cells to simultaneous treatment with sorafenib and radiofrequency current.
Oncology letters
Hernández-Bule ML,Martínez MA,Trillo MÁ,Martínez L,Toledano-Macías E,Úbeda A
44-680G was used in Western Blotting to analyze the effects of simultaneous treatment with sorafenib and 448-kHz, subthermal CRET current on the proliferation and viability of HepG2 cell cultures.
Mon Nov 01 00:00:00 EDT 2021
Response of human cancer cells to simultaneous treatment with sorafenib and radiofrequency current.
Oncology letters
Hernández-Bule ML,Martínez MA,Trillo MÁ,Martínez L,Toledano-Macías E,Úbeda A
44-680G was used in Western Blotting to analyze the effects of simultaneous treatment with sorafenib and 448-kHz, subthermal CRET current on the proliferation and viability of HepG2 cell cultures.
Mon Nov 01 00:00:00 EDT 2021
Hypoxia-inducible factor 1-alpha acts as a bridge factor for crosstalk between ERK1/2 and caspases in hypoxia-induced apoptosis of cementoblasts.
Journal of cellular and molecular medicine
Yong J,von Bremen J,Groeger S,Ruiz-Heiland G,Ruf S
44-680G was used in Western Blotting to provide evidence for the role of ERK1/2 and HIF-1α in the apoptotic response of OCCM-30 cells exposed to CoCl2 -mimicked hypoxia, providing potential new possibilities for molecular intervention in obese patients undergoing orthodontic treatment.
Fri Oct 01 00:00:00 EDT 2021
Adiponectin Interacts In-Vitro With Cementoblasts Influencing Cell Migration, Proliferation and Cementogenesis Partly Through the MAPK Signaling Pathway.
Frontiers in pharmacology
Yong J,von Bremen J,Ruiz-Heiland G,Ruf S
44-680G was used in Western Blotting to conclude that Adiponectin favorably affect OCCM-30 cell migration, proliferation as well as cementogenesis. One of the underlying mechanisms is the activation of MAPK signaling pathway.
Mon Jan 11 00:00:00 EST 2021
Adiponectin Interacts In-Vitro With Cementoblasts Influencing Cell Migration, Proliferation and Cementogenesis Partly Through the MAPK Signaling Pathway.
Frontiers in pharmacology
Yong J,von Bremen J,Ruiz-Heiland G,Ruf S
44-680G was used in Western Blotting to conclude that Adiponectin favorably affect OCCM-30 cell migration, proliferation as well as cementogenesis. One of the underlying mechanisms is the activation of MAPK signaling pathway.
Mon Jan 11 00:00:00 EST 2021
Role of thiocyanate in the modulation of myeloperoxidase-derived oxidant induced damage to macrophages.
Redox biology
Guo C,Davies MJ,Hawkins CL
44-680G was used in Western Blotting to provide further insight into the cellular pathways by which SCN- could exert protective effects on supplementation to decrease the development of chronic inflammatory diseases, such as atherosclerosis.
Tue Sep 01 00:00:00 EDT 2020
A novel protective role of sacubitril/valsartan in cyclophosphamide induced lung injury in rats: impact of miRNA-150-3p on NF-κB/MAPK signaling trajectories.
Scientific reports
Abdel-Latif GA,Elwahab AHA,Hasan RA,ElMongy NF,Ramzy MM,Louka ML,Schaalan MF
44-680G was used in Western Blotting to conclude that sacubitril/valsartan effectively abrogated the CP induced lung inflammation and fibrosis, providing a potential promising protection that could be linked to their ability to inhibit miR-150-3p via inhibition of NF-κB and MAPK signaling pathways.
Mon Aug 03 00:00:00 EDT 2020
A novel protective role of sacubitril/valsartan in cyclophosphamide induced lung injury in rats: impact of miRNA-150-3p on NF-κB/MAPK signaling trajectories.
Scientific reports
Abdel-Latif GA,Elwahab AHA,Hasan RA,ElMongy NF,Ramzy MM,Louka ML,Schaalan MF
44-680G was used in Western Blotting to conclude that sacubitril/valsartan effectively abrogated the CP induced lung inflammation and fibrosis, providing a potential promising protection that could be linked to their ability to inhibit miR-150-3p via inhibition of NF-κB and MAPK signaling pathways.
Mon Aug 03 00:00:00 EDT 2020
KLF9-dependent ROS regulate melanoma progression in stage-specific manner.
Oncogene
Bagati A,Moparthy S,Fink EE,Bianchi-Smiraglia A,Yun DH,Kolesnikova M,Udartseva OO,Wolff DW,Roll MV,Lipchick BC,Han Z,Kozlova NI,Jowdy P,Berman AE,Box NF,Rodriguez C,Bshara W,Kandel ES,Soengas MS,Paragh G,Nikiforov MA
44-680G was used in Immunohistochemistry to show the ubiquitous transcriptional regulator of oxidative stress KLF9 can mediated the production of ROS in premalignant melanocytes that is required for BRAFV600E-mediated cell proliferation.
Wed May 01 00:00:00 EDT 2019
Simvastatin Mitigates Apoptosis and Transforming Growth Factor-Beta Upregulation in Stretch-Induced Endothelial Cells.
Oxidative medicine and cellular longevity
Dong G,Huang X,Jiang S,Ni L,Chen S
44-680G was used in Western Blotting to determine whether continuous stretch induced by portal hypertension may impair the function of endothelial cells (ECs) in the portal vein and aggravate the progress of portal hypertension and explore its mechanism.
Fri Jun 19 00:00:00 EDT 2020
ANO6 promotes cell proliferation and invasion in glioma through regulating the ERK signaling pathway.
OncoTargets and therapy
Xuan ZB,Wang YJ,Xie J
Published figure using Phospho-ERK1/ERK2 (Thr185, Tyr187) polyclonal antibody (Product # 44-680G) in Western Blot
Mon Apr 11 00:00:00 EDT 2022
Intermittent hypoxia alleviates increased VEGF and pro-angiogenic potential in liver cancer cells.
Oncology letters
Dong G,Lin XH,Liu HH,Gao DM,Cui JF,Ren ZG,Chen RX
44-680G was used in Western Blotting to investigate the ability of intermittent hypoxia to alleviate the acute hypoxia-induced increase of VEGF and decrease the pro-angiogenic potential of liver cancer cells.
Thu Aug 01 00:00:00 EDT 2019
The role of fibroblast growth factor signalling in Echinococcus multilocularis development and host-parasite interaction.
PLoS neglected tropical diseases
Förster S,Koziol U,Schäfer T,Duvoisin R,Cailliau K,Vanderstraete M,Dissous C,Brehm K
44-680G was used in Western Blotting to study the molecular mechanisms of parasite organ tropism towards the liver and the influences of liver cytokines and hormones on parasite development.
Fri Mar 01 00:00:00 EST 2019
Repeated Sigma-1 Receptor Antagonist MR309 Administration Modulates Central Neuropathic Pain Development After Spinal Cord Injury in Mice.
Frontiers in pharmacology
Castany S,Codony X,Zamanillo D,Merlos M,Verdú E,Boadas-Vaello P
Published figure using Phospho-ERK1/ERK2 (Thr185, Tyr187) polyclonal antibody (Product # 44-680G) in Western Blot
Wed Sep 30 00:00:00 EDT 2020
Response of neuroblastoma cells to RF currents as a function of the signal frequency.
BMC cancer
Hernández-Bule ML,Medel E,Colastra C,Roldán R,Úbeda A
44-680G was used in Immunocytochemistry-immunoflourescence to study the effect of signal frequency in the response of the human neuroblastoma cell line NB69 to subthermal electric treatment.
Thu Sep 05 00:00:00 EDT 2019
Involvement of the EGF Receptor in MAPK Signaling Activation by a 50 Hz Magnetic Field in Human Neuroblastoma Cells.
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology
Martínez MA,Úbeda A,Trillo MÀ
44-680G was used in Immunocytochemistry-immunoflourescence to determine the role of the epidermal growth factor receptor in the field induced cell proliferation and activation of MAPK pathways.
Thu Apr 18 00:00:00 EDT 2019
ZO-1 protein is required for hydrogen peroxide to increase MDCK cell paracellular permeability in an ERK 1/2-dependent manner.
American journal of physiology. Cell physiology
Bilal S,Jaggi S,Janosevic D,Shah N,Teymour S,Voronina A,Watari J,Axis J,Amsler K
Published figure using Phospho-ERK1/ERK2 (Thr185, Tyr187) polyclonal antibody (Product # 44-680G) in Western Blot
Sat Sep 01 00:00:00 EDT 2018
FGF21 acts as a negative regulator of bile acid synthesis.
The Journal of endocrinology
Chen MM,Hale C,Stanislaus S,Xu J,Véniant MM
44-680G was used in Western Blotting to determine the role of FGF21 in bile acid metabolism.
Tue May 01 00:00:00 EDT 2018
CRB3 and the FERM protein EPB41L4B regulate proliferation of mammary epithelial cells through the release of amphiregulin.
PloS one
Walker SJ,Selfors LM,Margolis BL,Brugge JS
Published figure using Phospho-ERK1/ERK2 (Thr185, Tyr187) polyclonal antibody (Product # 44-680G) in Western Blot
Tue Apr 16 00:00:00 EDT 2019
Development of MK-8353, an orally administered ERK1/2 inhibitor, in patients with advanced solid tumors.
JCI insight
Moschos SJ,Sullivan RJ,Hwu WJ,Ramanathan RK,Adjei AA,Fong PC,Shapira-Frommer R,Tawbi HA,Rubino J,Rush TS,Zhang D,Miselis NR,Samatar AA,Chun P,Rubin EH,Schiller J,Long BJ,Dayananth P,Carr D,Kirschmeier P,Bishop WR,Deng Y,Cooper A,Shipps GW,Moreno BH,Robert L,Ribas A,Flaherty KT
44-680G was used in Western Blotting to develop an orally bioavailable ERK inhibitor, and demonstrate its efficacy in patients with advanced solid tumours.
Thu Feb 22 00:00:00 EST 2018
Critical role of sigma-1 receptors in central neuropathic pain-related behaviours after mild spinal cord injury in mice.
Scientific reports
Castany S,Gris G,Vela JM,Verdú E,Boadas-Vaello P
44-680G was used in Western Blotting to show that sigma-1 receptor may modulate central neuropathic pain and point to regulation of sensitisation-related phenomena as a possible mechanism.
Thu Mar 01 00:00:00 EST 2018
Hematopoietic cell kinase (HCK) is a potential therapeutic target for dysplastic and leukemic cells due to integration of erythropoietin/PI3K pathway and regulation of erythropoiesis: HCK in erythropoietin/PI3K pathway.
Biochimica et biophysica acta. Molecular basis of disease
Roversi FM,Pericole FV,Machado-Neto JA,da Silva Santos Duarte A,Longhini AL,Corrocher FA,Palodetto B,Ferro KP,Rosa RG,Baratti MO,Verjovski-Almeida S,Traina F,Molinari A,Botta M,Saad ST
44680G was used in western blot to characterize a new specific pharmacological hematopoietic cell kinase inhibitor
Wed Feb 01 00:00:00 EST 2017
WNK1 kinase balances T cell adhesion versus migration in vivo.
Nature immunology
Köchl R,Thelen F,Vanes L,Brazão TF,Fountain K,Xie J,Huang CL,Lyck R,Stein JV,Tybulewicz VL
44680G was used in western blot to discover that WNK1 kinase regulates integrin-mediated adhesion and T cell migration
Thu Sep 01 00:00:00 EDT 2016
ERK and p38 MAPK Activities Determine Sensitivity to PI3K/mTOR Inhibition via Regulation of MYC and YAP.
Cancer research
Muranen T,Selfors LM,Hwang J,Gallegos LL,Coloff JL,Thoreen CC,Kang SA,Sabatini DM,Mills GB,Brugge JS
Published figure using Phospho-ERK1/ERK2 (Thr185, Tyr187) polyclonal antibody (Product # 44-680G) in Western Blot
Thu Dec 15 00:00:00 EST 2016
Oxidative pentose phosphate pathway inhibition is a key determinant of antimalarial induced cancer cell death.
Oncogene
Salas E,Roy S,Marsh T,Rubin B,Debnath J
44-680G was used in western blot to show that inhibition of the oxidative arm of the pentose phosphate pathway is required for antimalarial-mediated apoptosis.
Thu Jun 02 00:00:00 EDT 2016
Targeting the PI3K/AKT/mTOR pathway overcomes the stimulating effect of dabrafenib on the invasive behavior of melanoma cells with acquired resistance to the BRAF inhibitor.
International journal of oncology
Caporali S,Alvino E,Lacal PM,Levati L,Giurato G,Memoli D,Caprini E,Antonini Cappellini GC,D'Atri S
44680G was used in western blot to compare dabrafenib-resistant and -sensitive BRAF-mutant human melanoma cell lines
Thu Sep 01 00:00:00 EDT 2016
Endosomal Na+/H+ exchanger NHE5 influences MET recycling and cell migration.
Molecular biology of the cell
Fan SH,Numata Y,Numata M
44-680G was used in western blot to investigate the role of neuron-enriched Na(+)/H(+) exchanger NHE5
Mon Feb 15 00:00:00 EST 2016
Haem-dependent dimerization of PGRMC1/Sigma-2 receptor facilitates cancer proliferation and chemoresistance.
Nature communications
Kabe Y,Nakane T,Koike I,Yamamoto T,Sugiura Y,Harada E,Sugase K,Shimamura T,Ohmura M,Muraoka K,Yamamoto A,Uchida T,Iwata S,Yamaguchi Y,Krayukhina E,Noda M,Handa H,Ishimori K,Uchiyama S,Kobayashi T,Suematsu M
44-680G was used in western blot to determine facilitation of chemoresistance and cancer proliferation by Haem-dependent dimerization of PGRMC1/Sigma-2 receptor
Fri Mar 18 00:00:00 EDT 2016
Anti-c-Met monoclonal antibody ABT-700 breaks oncogene addiction in tumors with MET amplification.
BMC cancer
Wang J,Goetsch L,Tucker L,Zhang Q,Gonzalez A,Vaidya KS,Oleksijew A,Boghaert E,Song M,Sokolova I,Pestova E,Anderson M,Pappano WN,Ansell P,Bhathena A,Naumovski L,Corvaia N,Reilly EB
44-680G was used in immunohistochemistry - paraffin section and western blot to learn how oncogene addiction can be broken in tumors with MET amplification by the Anti-c-Met monoclonal antibody ABT-700
Tue Feb 16 00:00:00 EST 2016
Anti-c-Met monoclonal antibody ABT-700 breaks oncogene addiction in tumors with MET amplification.
BMC cancer
Wang J,Goetsch L,Tucker L,Zhang Q,Gonzalez A,Vaidya KS,Oleksijew A,Boghaert E,Song M,Sokolova I,Pestova E,Anderson M,Pappano WN,Ansell P,Bhathena A,Naumovski L,Corvaia N,Reilly EB
44-680G was used in immunohistochemistry - paraffin section and western blot to learn how oncogene addiction can be broken in tumors with MET amplification by the Anti-c-Met monoclonal antibody ABT-700
Tue Feb 16 00:00:00 EST 2016
Power Frequency Magnetic Fields Affect the p38 MAPK-Mediated Regulation of NB69 Cell Proliferation Implication of Free Radicals.
International journal of molecular sciences
Martínez MA,Úbeda A,Moreno J,Trillo MÁ
44-680G was used in Immunocytochemistry to investigate the effect of magnetic fields on the p38 MAPK-mediated regulation of NB69 cell proliferation and the potential involvement of free radicals.
Wed Apr 06 00:00:00 EDT 2016
ATG12-ATG3 interacts with Alix to promote basal autophagic flux and late endosome function.
Nature cell biology
Murrow L,Malhotra R,Debnath J
Published figure using Phospho-ERK1/ERK2 (Thr185, Tyr187) polyclonal antibody (Product # 44-680G) in Western Blot
Sun Mar 01 00:00:00 EST 2015
A new water soluble MAPK activator exerts antitumor activity in melanoma cells resistant to the BRAF inhibitor vemurafenib.
Biochemical pharmacology
Graziani G,Artuso S,De Luca A,Muzi A,Rotili D,Scimeca M,Atzori MG,Ceci C,Mai A,Leonetti C,Levati L,Bonanno E,Tentori L,Caccuri AM
44-680G was used in western blot to test if NBDHEX and MC3181 have antitumor activity against melanoma cells resistant to vemurafenib
Fri May 01 00:00:00 EDT 2015
All-Trans Retinoic Acid Induces Proliferation, Survival, and Migration in A549 Lung Cancer Cells by Activating the ERK Signaling Pathway through a Transcription-Independent Mechanism.
BioMed research international
Quintero Barceinas RS,García-Regalado A,Aréchaga-Ocampo E,Villegas-Sepúlveda N,González-De la Rosa CH
Published figure using Phospho-ERK1/ERK2 (Thr185, Tyr187) polyclonal antibody (Product # 44-680G) in Western Blot
Fri Aug 26 00:00:00 EDT 2016
All-Trans Retinoic Acid Induces Proliferation, Survival, and Migration in A549 Lung Cancer Cells by Activating the ERK Signaling Pathway through a Transcription-Independent Mechanism.
BioMed research international
Quintero Barceinas RS,García-Regalado A,Aréchaga-Ocampo E,Villegas-Sepúlveda N,González-De la Rosa CH
Published figure using Phospho-ERK1/ERK2 (Thr185, Tyr187) polyclonal antibody (Product # 44-680G) in Western Blot
Fri Aug 26 00:00:00 EDT 2016
Possible Mechanisms of Di(2-ethylhexyl) Phthalate-Induced MMP-2 and MMP-9 Expression in A7r5 Rat Vascular Smooth Muscle Cells.
International journal of molecular sciences
Shih MF,Pan KH,Cherng JY
Published figure using Phospho-ERK1/ERK2 (Thr185, Tyr187) polyclonal antibody (Product # 44-680G) in Western Blot
Fri Dec 04 00:00:00 EST 2015
A rapid and convenient method for fluorescence analysis of in vitro cultivated metacestode vesicles from Echinococcus multilocularis.
PloS one
Cheng Z,Liu F,Zhu S,Tian H,Wang L,Wang Y
Published figure using Phospho-ERK1/ERK2 (Thr185, Tyr187) polyclonal antibody (Product # 44-680G) in Immunofluorescence
Fri Jan 22 00:00:00 EST 2016
Candidate tumor suppressor B-cell translocation gene 3 impedes neoplastic progression by suppression of AKT.
Cell death & disease
Cheng YC,Chen PH,Chiang HY,Suen CS,Hwang MJ,Lin TY,Yang HC,Lin WC,Lai PL,Shieh SY
44-680G was used in western blot to elucidate the tumor suppressor function of BTG3
Thu Jan 08 00:00:00 EST 2015
Increased ERK and JNK activation and decreased ERK/JNK ratio are associated with long-term organ damage in patients with systemic lupus erythematosus.
Rheumatology (Oxford, England)
Bloch O,Amit-Vazina M,Yona E,Molad Y,Rapoport MJ
44-680G was used in western blot to test if extracellular signal-regulated kinase and c-Jun N-terminal kinase are associated with long-term organ damage in SLE patients.
Sun Jun 01 00:00:00 EDT 2014
The MEK1/2-ERK1/2 pathway is activated in chronic rhinosinusitis with nasal polyps.
Archivum immunologiae et therapiae experimentalis
Linke R,Pries R,Könnecke M,Bruchhage KL,Böscke R,Gebhard M,Wollenberg B
44-680G was used in immunohistochemistry and western blot to assess the role of the MEK/2-ERK/2 signaling pathway in the pathogenesis of chronic rhinosinusitis with nasal polyps.
Sun Jun 01 00:00:00 EDT 2014
Silver and fullerene nanoparticles' effect on interleukin-2-dependent proliferation of CD4 (+) T cells.
Toxicology in vitro : an international journal published in association with BIBRA
Côté-Maurais G,Bernier J
44-680G was used in western blot to determine if nanoparticles inhibit IL-2-dependent T cell proliferation.
Mon Dec 01 00:00:00 EST 2014
The C-terminus of human nucleotide receptor P2X7 is critical for receptor oligomerization and N-linked glycosylation.
PloS one
Wickert LE,Blanchette JB,Waldschmidt NV,Bertics PJ,Denu JM,Denlinger LC,Lenertz LY
44-680G was used in western blot to alter the C-terminal trafficking domain of P2X7 and examine its function.
Mon Dec 30 00:00:00 EST 2013
Molecular pathway profiling of T lymphocyte signal transduction pathways; Th1 and Th2 genomic fingerprints are defined by TCR and CD28-mediated signaling.
BMC immunology
Smeets RL,Fleuren WW,He X,Vink PM,Wijnands F,Gorecka M,Klop H,Bauerschmidt S,Garritsen A,Koenen HJ,Joosten I,Boots AM,Alkema W
Published figure using Phospho-ERK1/ERK2 (Thr185, Tyr187) polyclonal antibody (Product # 44-680G) in Western Blot
Wed Mar 14 00:00:00 EDT 2012
TFG-1 function in protein secretion and oncogenesis.
Nature cell biology
Witte K,Schuh AL,Hegermann J,Sarkeshik A,Mayers JR,Schwarze K,Yates JR,Eimer S,Audhya A
Published figure using Phospho-ERK1/ERK2 (Thr185, Tyr187) polyclonal antibody (Product # 44-680G) in Western Blot
Sun May 01 00:00:00 EDT 2011
TFG-1 function in protein secretion and oncogenesis.
Nature cell biology
Witte K,Schuh AL,Hegermann J,Sarkeshik A,Mayers JR,Schwarze K,Yates JR,Eimer S,Audhya A
Published figure using Phospho-ERK1/ERK2 (Thr185, Tyr187) polyclonal antibody (Product # 44-680G) in Western Blot
Sun May 01 00:00:00 EDT 2011
ErbB2 stabilizes epidermal growth factor receptor (EGFR) expression via Erk and Sprouty2 in extracellular matrix-detached cells.
The Journal of biological chemistry
Grassian AR,Schafer ZT,Brugge JS
44-680G was used in western blot to investigate the roles of EGFR and beta1 integrin in ErbB2-driven anchorage independence of tumor cells
Fri Jan 07 00:00:00 EST 2011
ErbB2 stabilizes epidermal growth factor receptor (EGFR) expression via Erk and Sprouty2 in extracellular matrix-detached cells.
The Journal of biological chemistry
Grassian AR,Schafer ZT,Brugge JS
44-680G was used in western blot to investigate the roles of EGFR and beta1 integrin in ErbB2-driven anchorage independence of tumor cells
Fri Jan 07 00:00:00 EST 2011
3-phosphoinositide-dependent protein kinase-1 regulates proliferation and survival of cancer cells with an activated mitogen-activated protein kinase pathway.
Molecular cancer research : MCR
Lu Z,Cox-Hipkin MA,Windsor WT,Boyapati A
44-680G was used in western blot to examine how PDK1 affects MAPK and PI3K signaling in tumor cells
Mon Mar 01 00:00:00 EST 2010
Mutation of putative N-linked glycosylation sites on the human nucleotide receptor P2X7 reveals a key residue important for receptor function.
Biochemistry
Lenertz LY,Wang Z,Guadarrama A,Hill LM,Gavala ML,Bertics PJ
Published figure using Phospho-ERK1/ERK2 (Thr185, Tyr187) polyclonal antibody (Product # 44-680G) in Western Blot
Tue Jun 08 00:00:00 EDT 2010
Induction of invasion in an organotypic oral cancer model by CoCl2, a hypoxia mimetic.
European journal of oral sciences
Brusevold IJ,Husvik C,Schreurs O,Schenck K,Bryne M,Søland TM
44-680G was used in immunohistochemistry to develop an in vitro model for experimental studies of cancer cell invasion
Thu Apr 01 00:00:00 EDT 2010
Extranuclear estrogen receptors mediate the neuroprotective effects of estrogen in the rat hippocampus.
PloS one
Yang LC,Zhang QG,Zhou CF,Yang F,Zhang YD,Wang RM,Brann DW
44-680G was used in immunocytochemistry and western blot to investigate the potential neuroprotective effects of extranuclear estrogen receptors in the brain following cerebral ischemia
Fri May 07 00:00:00 EDT 2010
Extranuclear estrogen receptors mediate the neuroprotective effects of estrogen in the rat hippocampus.
PloS one
Yang LC,Zhang QG,Zhou CF,Yang F,Zhang YD,Wang RM,Brann DW
44-680G was used in immunocytochemistry and western blot to investigate the potential neuroprotective effects of extranuclear estrogen receptors in the brain following cerebral ischemia
Fri May 07 00:00:00 EDT 2010
Extranuclear estrogen receptors mediate the neuroprotective effects of estrogen in the rat hippocampus.
PloS one
Yang LC,Zhang QG,Zhou CF,Yang F,Zhang YD,Wang RM,Brann DW
44-680G was used in immunocytochemistry and western blot to investigate the potential neuroprotective effects of extranuclear estrogen receptors in the brain following cerebral ischemia
Fri May 07 00:00:00 EDT 2010
Antioxidant and oncogene rescue of metabolic defects caused by loss of matrix attachment.
Nature
Schafer ZT,Grassian AR,Song L,Jiang Z,Gerhart-Hines Z,Irie HY,Gao S,Puigserver P,Brugge JS
Published figure using Phospho-ERK1/ERK2 (Thr185, Tyr187) polyclonal antibody (Product # 44-680G) in Western Blot
Thu Sep 03 00:00:00 EDT 2009
The absence of caveolin-1 increases proliferation and anchorage- independent growth by a Rac-dependent, Erk-independent mechanism.
Molecular and cellular biology
Cerezo A,Guadamillas MC,Goetz JG,Sánchez-Perales S,Klein E,Assoian RK,del Pozo MA
44-680G was used in western blot to elucidate the mechanisms by which loss of Cav1 function promotes cancer cell growth
Tue Sep 01 00:00:00 EDT 2009
Dissection of the osteogenic effects of laminin-332 utilizing specific LG domains: LG3 induces osteogenic differentiation, but not mineralization.
Experimental cell research
Klees RF,Salasznyk RM,Ward DF,Crone DE,Williams WA,Harris MP,Boskey A,Quaranta V,Plopper GE
44-680G was used in western blot to study the role of laminins during osteogenic differentiation of human mesenchymal stem cells
Fri Feb 15 00:00:00 EST 2008
A study of phosphorylated ERK1/2 and COX-2 in early stage (T1-T2) oral squamous cell carcinomas.
Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology
Søland TM,Husvik C,Koppang HS,Boysen M,Sandvik L,Clausen OP,Christoffersen T,Bryne M
44-680G was used in immunohistochemistry - paraffin section to assess the prognostic value of activated phosphorylated ERK1 and ERK2 and COX-2 at the invasive front and in central/superficial parts of oral squamous cell carcinomas
Wed Oct 01 00:00:00 EDT 2008
Quantitative measurement of epidermal growth factor receptor-mitogen-activated protein kinase signal transduction using a nine-plex, peptide-based immunoassay.
Analytical biochemistry
Rauh-Adelmann C,Moskow JM,Graham JR,Yen LG,Boucher JI,Murphy CE,Nadler TK,Gordon NF,Radding JA
44-680G was used in western blot to develop an assay to measure temporal, site-specific phosphorylation of key members of the EGFR pathway in A431 cells stimulated with epidermal growth factor
Tue Apr 15 00:00:00 EDT 2008
Molecular mechanisms involved in interleukin-4-induced human neutrophils: expression and regulation of suppressor of cytokine signaling.
Journal of leukocyte biology
Ratthé C,Pelletier M,Chiasson S,Girard D
Tue May 01 00:00:00 EDT 2007
Activation of FAK is necessary for the osteogenic differentiation of human mesenchymal stem cells on laminin-5.
Journal of cellular biochemistry
Salasznyk RM,Klees RF,Boskey A,Plopper GE
44-680G was used in western blot to report that FAK is an important mediator of laminin-5-induced osteogenic differentiation of human mesenchymal stem cells
Thu Feb 01 00:00:00 EST 2007
The mitogen-activated protein kinases (MAPK) p38 and JNK are markers of tumor progression in breast carcinoma.
Gynecologic oncology
Davidson B,Konstantinovsky S,Kleinberg L,Nguyen MT,Bassarova A,Kvalheim G,Nesland JM,Reich R
Fri Sep 01 00:00:00 EDT 2006
Epidermal growth factor receptor induced Erk phosphorylation in the suprachiasmatic nucleus.
Brain research
Hao H,Schwaber J
44-680G was used in immunohistochemistry - free floating to report that epidermal growth factor treatment induced Erk1/2 phosphorylation in rat suprachiasmatic nucleus cells
Tue May 09 00:00:00 EDT 2006
Phospho-caveolin-1 mediates integrin-regulated membrane domain internalization.
Nature cell biology
del Pozo MA,Balasubramanian N,Alderson NB,Kiosses WB,Grande-García A,Anderson RG,Schwartz MA
Thu Sep 01 00:00:00 EDT 2005
Phospho-caveolin-1 mediates integrin-regulated membrane domain internalization.
Nature cell biology
del Pozo MA,Balasubramanian N,Alderson NB,Kiosses WB,Grande-García A,Anderson RG,Schwartz MA
Thu Sep 01 00:00:00 EDT 2005
CHIR-258: a potent inhibitor of FLT3 kinase in experimental tumor xenograft models of human acute myelogenous leukemia.
Clinical cancer research : an official journal of the American Association for Cancer Research
Lopes de Menezes DE,Peng J,Garrett EN,Louie SG,Lee SH,Wiesmann M,Tang Y,Shephard L,Goldbeck C,Oei Y,Ye H,Aukerman SL,Heise C
Fri Jul 15 00:00:00 EDT 2005
Mitogen-activated protein kinase expression and activation does not differentiate benign from malignant mesothelial cells.
Cancer
Vintman L,Nielsen S,Berner A,Reich R,Davidson B
Wed Jun 01 00:00:00 EDT 2005
Heat shock protein 60 inhibits Th1-mediated hepatitis model via innate regulation of Th1/Th2 transcription factors and cytokines.
Journal of immunology (Baltimore, Md. : 1950)
Zanin-Zhorov A,Bruck R,Tal G,Oren S,Aeed H,Hershkoviz R,Cohen IR,Lider O
Tue Mar 15 00:00:00 EST 2005
Heat shock protein 60 inhibits Th1-mediated hepatitis model via innate regulation of Th1/Th2 transcription factors and cytokines.
Journal of immunology (Baltimore, Md. : 1950)
Zanin-Zhorov A,Bruck R,Tal G,Oren S,Aeed H,Hershkoviz R,Cohen IR,Lider O
Tue Mar 15 00:00:00 EST 2005
Chemokine receptor CCR2 expression by systemic sclerosis fibroblasts: evidence for autocrine regulation of myofibroblast differentiation.
Arthritis and rheumatism
Carulli MT,Ong VH,Ponticos M,Shiwen X,Abraham DJ,Black CM,Denton CP
44-680G was used in western blot to assess the contribution of CCL2/CCR2 signaling to systemic sclerosis
Thu Dec 01 00:00:00 EST 2005
