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Product Details
10101-2-AP
Species Reactivity
Published species
Host/Isotype
Class
Type
Immunogen
Conjugate
Form
Concentration
Purification
Storage buffer
Contains
Storage conditions
Shipping conditions
Product Specific Information
This antibody is specific to PITRM1.
Immunogen sequence: NGIPDSGHL YASIRAGRTL TPAGDLQETF SGMDQVRLMK RIAEMTDIKP ILRKLPRIKK HLLNGDNMRC SVNATPQQMP QTEKAVEDFL RSIGRSKKER RPVRPHTVEK PVPSSSGGDA HVPHGSQVIR KLVMEPTFKP WQMKTHFLMP FPVNYVGECI RTVPYTDPDH ASLKILARLM TAKFLHTEIR EKGGAYGGGA KLSHNGIFTL YSYRDPNTIE TLQSFGKAVD WAKSGKFTQQ DIDEAKLSVF STVDAPVAPS DKGMDHFLYG LSDEMKQAHR EQLFAVSHDK LLAVSDRYLG T (209-508 aa encoded by BC001150)
Target Information
The protein encoded by this gene is an ATP-dependent metalloprotease that degrades post-cleavage mitochondrial transit peptides. The encoded protein binds zinc and can also degrade amyloid beta A4 protein, suggesting a possible role in Alzheimer's disease.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: hPreP; Metalloprotease 1; metalloprotease 1 (pitrilysin family); nuclear transplantation upregulated protein 1; pitrilysin metallepetidase 1; pitrilysin metalloprotease 1; Pitrilysin metalloproteinase 1; PreP peptidasome; Presequence protease, mitochondrial
Gene Aliases: 2310012C15Rik; AA410010; KIAA1104; mKIAA1104; MP-1; MP1; Ntup1; PITRM1; PREP
UniProt ID: (Human) Q5JRX3, (Mouse) Q8K411
Entrez Gene ID: (Human) 10531, (Mouse) 69617, (Rat) 307081
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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