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Invitrogen
PDK1 Monoclonal Antibody (4A11)
Product Details
MA5-15797
Species Reactivity
Published species
Host/Isotype
Class
Type
Clone
Immunogen
Conjugate
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RRID
Product Specific Information
MA5-15797 targets PDK1 in indirect ELISA, FACS, IF, IHC, and WB applications and shows reactivity with Human, Non-human primate, and Rat samples.
The MA5-15797 immunogen is purified recombinant fragment of human PDK1 expressed in E. Coli.
MA5-15797 detects PDK1 which has a predicted molecular weight of approximately 44kDa.
Target Information
PDK1 (3-phosphoinositide dependent kinase-1) is a serine/threonine protein kinase localized to the plasma membrane. It plays a vital role in insulin-induced glycogen synthesis, PKC activation, and activation of the AGC subfamily of protein kinases. Plays an important role in cellular responses to hypoxia and is important for cell proliferation under hypoxia. Protects cells against apoptosis in response to hypoxia and oxidative stress.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial; [Pyruvate dehydrogenase [lipoamide]] kinase isozyme 1, mitochondrial; isoenzyme 1; kinase isoenzyme 1; lipoamide; mitochondrial pyruvate dehydrogenase, lipoamide, kinase isoenzyme 1; PDH kinase 1; PDK p48; pyruvate dehydrogenase; pyruvate dehydrogenase kinase 1; Pyruvate dehydrogenase kinase isoform 1; pyruvate dehydrogenase kinase, isoenzyme 1; pyruvate dehydrogenase kinase, isozyme 1
Gene Aliases: B830012B01; D530020C15Rik; PDHK1; PDK1
UniProt ID: (Human) Q15118, (Mouse) Q8BFP9
Entrez Gene ID: (Human) 5163, (Rat) 116551, (Mouse) 228026
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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