Invitrogen

MOG Polyclonal Antibody

Advanced Verification

This Antibody was verified by Relative expression to ensure that the antibody binds to the antigen stated.

1 Published Figure

2 References

View all (19) MOG antibodies

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FIGURE: 1 / 4

MOG Antibody (PA5-19602) in WB

Western blot was performed using Anti-MOG Polyclonal Antibody (Product # PA5-19602) and a 27 kDa band corresponding to Myelin-oligodendrocyte glycoprotein was observed in Mouse and Rat Brain and Cerebellum but not in Heart and Liver. Tissue extracts (30 µg lysate) of Mouse Brain (Lane 1), Rat Brain (Lane 2), Mouse Cerebellum (Lane 3), Rat Cerebellum (Lane 4), Mouse Heart (Lane 5), Rat Heart (Lane 6), Mouse Liver (Lane 7) or Rat Liver (Lane 8) were electrophoresed using NuPAGE™ 10% Bis-Tris Protein Gel (Product # NP0301BOX). Resolved protei... View More

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MOG Antibody — Antibody specificity was demonstrated by detection of differential basal expression of the target across Mouse Brain, Rat Brain, Mouse Cerebellum, Rat Cerebellum, Mouse Heart, Rat Heart, Mouse Liver, Rat Liver owing to their inherent genetic constitution. Relative expression of Myelin-oligodendrocyte glycoprotein was observed in Mouse and Rat Brain and Cerebellum as compared to Heart and Liver using Anti-MOG Polyclonal Antibody (Product # PA5-19602) in Western Blot. {RE}

Product Details

PA5-19602

Applications

Tested Dilution

Publications

Western Blot (WB)

1:1,000

View 1 publication 1 publication

Immunohistochemistry (IHC)

View 1 publication 1 publication

Immunohistochemistry (Frozen) (IHC (F))

Assay-Dependent

Immunoprecipitation (IP)

5 µg/mL

Product Specifications

Species Reactivity

Mouse, Rat

Published species

Bovine, Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Synthetic peptide conjugated to KLH derived from within residues 200 to the C-terminus of Rat Myelin oligodendrocyte glycoprotein.

View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.4, with 1% BSA

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_11003093

Product Specific Information

This antibody is predicted to react with cow, human and common marmoset based on sequence homology.

Store antibody at 4ºC for 1-2 weeks. For long-term storage, store at -20ºC.

Target Information

The product of this gene is a membrane protein expressed on the oligodendrocyte cell surface and the outermost surface of myelin sheaths. Due to this localization, it is a primary target antigen involved in immune-mediated demyelination. This protein may be involved in completion and maintenance of the myelin sheath and in cell-cell communication. Alternatively spliced transcript variants encoding different isoforms have been identified.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

Huntington disease oligodendrocyte maturation deficits revealed by single-nucleus RNAseq are rescued by thiamine-biotin supplementation.

Nature communications

Lim RG,Al-Dalahmah O,Wu J,Gold MP,Reidling JC,Tang G,Adam M,Dansu DK,Park HJ,Casaccia P,Miramontes R,Reyes-Ortiz AM,Lau A,Hickman RA,Khan F,Paryani F,Tang A,Ofori K,Miyoshi E,Michael N,McClure N,Flowers XE,Vonsattel JP,Davidson S,Menon V,Swarup V,Fraenkel E,Goldman JE,Thompson LM

PA5-19602 was used in Immunohistochemistry (Frozen), Immunoprecipitation, Western Blot to identify cell type-specific and -agnostic signatures suggesting oligodendrocytes (OLs) and oligodendrocyte precursors (OPCs) are arrested in intermediate maturation states.

Wed Dec 21 00:00:00 EST 2022

Huntington disease oligodendrocyte maturation deficits revealed by single-nucleus RNAseq are rescued by thiamine-biotin supplementation.

Nature communications

Wed Dec 21 00:00:00 EST 2022

Environment and Behavior: Neurochemical Effects of Different Diets in the Calf Brain.

Animals : an open access journal from MDPI

Peli A,Grandis A,Tassinari M,Famigli Bergamini P,Tagliavia C,Roccaro M,Bombardi C

PA5-19602 was used in Immunohistochemistry to support the importance of maintaining a nutritional lifestyle similar to that occurring in natural conditions.

Fri Jun 14 00:00:00 EDT 2019

Bioinformatics

Protein Aliases: DAQB-92E24.2; dystonia 2, torsion (autosomal recessive); MGC26137; MOG alpha 6; MOG alpha-6; MOG Ig AluB; MOGIG-2; Myelin-oligodendrocyte glycoprotein

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Gene Aliases: B230317G11Rik; Mog

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UniProt ID: (Mouse) Q61885

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Entrez Gene ID: (Mouse) 17441, (Rat) 24558

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Function(s)

molecular_function immunoglobulin receptor superfamily

Process(es)

cell adhesion positive regulation of MyD88-dependent toll-like receptor signaling pathway aging response to lipid response to folic acid

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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MOG Polyclonal Antibody

MOG Antibody (PA5-19602) in WB

Product Details

PA5-19602

Western Blot (WB)

Immunohistochemistry (IHC)

Immunohistochemistry (Frozen) (IHC (F))

Immunoprecipitation (IP)

Species Reactivity

Published species

Host/Isotype

Class

Type

Immunogen

Conjugate

Form

Concentration

Purification

Storage buffer

Contains

Storage conditions

Shipping conditions

RRID

Product Specific Information

Target Information

Bioinformatics

Performance Guarantee

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