Product References
Attenuation of Tumor Burden in Response to Rucaparib in Lung Adenocarcinoma: The Contribution of Oxidative Stress, Apoptosis, and DNA Damage.
International journal of molecular sciences
Pérez-Peiró M,Valentí-Serra P,León-González B,Ampurdanés C,Duran X,Yélamos J,Barreiro E
A-21285 was used in Western Blotting to propose the contribution of PARP inhibitors to reduced tumor burden in lung adenocarcinoma.
Mon Jan 30 00:00:00 EST 2023
The pro- and antineoplastic effects of deoxycholic acid in pancreatic adenocarcinoma cell models.
Molecular biology reports
Schwarcz S,Kovács P,Kovács T,Ujlaki G,Nyerges P,Uray K,Bai P,Mikó E
A-21285 was used in Western Blotting to show that DCA induced antineoplastic effects in pancreatic adenocarcinoma cells by inhibiting EMT, reducing cancer stemness, and inducing oxidative/nitrosative stress and procarcinogenic effects such as hypermetabolic bioenergetics.
Thu Jun 01 00:00:00 EDT 2023
α-Syn overexpression, NRF2 suppression, and enhanced ferroptosis create a vicious cycle of neuronal loss in Parkinson's disease.
Free radical biology & medicine
A A,W C,N N,L M,M D,Zhang DD
A-21285 was used in Western Blotting to indicate that NRF2 is a critical anti-ferroptotic mediator of neuronal survival, and that the vicious cycle of α-syn overexpression and NRF2 suppression, leading to enhanced neuronal ferroptotic cell death, could represent a targetable and currently untapped means of preventing PD onset and progression.
Tue Nov 01 00:00:00 EDT 2022
Inducible Slc4a11 Knockout Triggers Corneal Edema Through Perturbation of Corneal Endothelial Pump.
Investigative ophthalmology & visual science
Ogando DG,Shyam R,Kim ET,Wang YC,Liu CY,Bonanno JA
A-21285 was used in Immunohistochemistry to examine early events following loss of Slc4a11 activity.
Tue Jun 01 00:00:00 EDT 2021
Inducible Slc4a11 Knockout Triggers Corneal Edema Through Perturbation of Corneal Endothelial Pump.
Investigative ophthalmology & visual science
Ogando DG,Shyam R,Kim ET,Wang YC,Liu CY,Bonanno JA
A-21285 was used in Immunohistochemistry to examine early events following loss of Slc4a11 activity.
Tue Jun 01 00:00:00 EDT 2021
Interplay of two transcription factors for recruitment of the chromatin remodeling complex modulates fungal nitrosative stress response.
Nature communications
Jian Y,Liu Z,Wang H,Chen Y,Yin Y,Zhao Y,Ma Z
Published figure using Nitrotyrosine polyclonal antibody (Product # A-21285) in Western Blot
Thu May 06 00:00:00 EDT 2021
Nutraceutical Strategy to Counteract Eye Neurodegeneration and Oxidative Stress in Drosophila melanogaster Fed with High-Sugar Diet.
Antioxidants (Basel, Switzerland)
Catalani E,Fanelli G,Silvestri F,Cherubini A,Del Quondam S,Bongiorni S,Taddei AR,Ceci M,De Palma C,Perrotta C,Rinalducci S,Prantera G,Cervia D
A-21285 was used in Immunohistochemistry-immunofluorescence to demonstrate that the continuous supplementation with the alimentary integrator Lisosan G exerts a robust and multifaceted antioxidant effect on retinal neurons, thus providing efficacious neuroprotection of hyperglycemic eye.
Tue Jul 27 00:00:00 EDT 2021
Antioxidant Solution in Combination with Angiotensin-(1-7) Provides Myocardial Protection in Langendorff-Perfused Rat Hearts.
Oxidative medicine and cellular longevity
Andrä M,Russ M,Jauk S,Lamacie M,Lang I,Arnold R,Brcic I,Santos R,Wintersteiger R,Ortner A
A-21285 was used in Immunohistochemistry to indicate substantial cardioprotection of the novel combination with promising prospective for future clinical use.
Thu May 13 00:00:00 EDT 2021
Mice deficient in pyruvate dehydrogenase kinase 4 are protected against acetaminophen-induced hepatotoxicity.
Toxicology and applied pharmacology
Duan L,Ramachandran A,Akakpo JY,Woolbright BL,Zhang Y,Jaeschke H
A-21285 was used in Immunohistochemistry to show a pronounced protective effect of PDK4-deficient mice against APAP hepatotoxicity due to the inhibition of the mitochondrial oxidant stress and peroxynitrite formation.
Wed Jan 15 00:00:00 EST 2020
Hormetic-Like Effects of L-Homocysteine on Synaptic Structure, Function, and Aβ Aggregation.
Pharmaceuticals (Basel, Switzerland)
Montecinos-Oliva C,Arrázola MS,Jara C,Tapia-Rojas C,Inestrosa NC
Published figure using Nitrotyrosine polyclonal antibody (Product # A-21285) in Western Blot
Sun Feb 02 00:00:00 EST 2020
AP39, a Modulator of Mitochondrial Bioenergetics, Reduces Antiangiogenic Response and Oxidative Stress in Hypoxia-Exposed Trophoblasts: Relevance for Preeclampsia Pathogenesis.
The American journal of pathology
Covarrubias AE,Lecarpentier E,Lo A,Salahuddin S,Gray KJ,Karumanchi SA,Zsengellér ZK
A-21285 was used in Immunohistochemistry to show that placental hypoxia induces reactive oxygen species production, HIF-1α stabilization, and sFLT1 up-regulation; these pathophysiological alterations can be attenuated by mitochondrial-targeted antioxidants.
Tue Jan 01 00:00:00 EST 2019
Apocynin and Tempol ameliorate dietary sodium-induced declines in cutaneous microvascular function in salt-resistant humans.
American journal of physiology. Heart and circulatory physiology
Ramick MG,Brian MS,Matthews EL,Patik JC,Seals DR,Lennon SL,Farquhar WB,Edwards DG
A-21285 was used in Immunocytochemistry-immunoflourescence to provide direct evidence of dietary sodium-induced endothelial cell oxidative stress and suggest that NADPH-derived reactive oxygen species contribute to sodium-induced declines in microvascular function.
Mon Jul 01 00:00:00 EDT 2019
Investigation of antioxidative effects of a cardioprotective solution in heart tissue.
Molecular and cellular biochemistry
Russ M,Jauk S,Wintersteiger R,Andrä M,Brcic I,Ortner A
A-21285 was used in Immunohistochemistry to suggest a novel approach against oxidative stress situations, for example at ischemia reperfusion injury during heart transplantations.
Fri Nov 01 00:00:00 EDT 2019
Renal dysfunction aggravated impaired cutaneous wound healing in diabetic mice.
Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society
Xie P,Young MW,Bian H,Niknam-Bienia S,Hong S,Mustoe TA,Galiano RD
A-21285 was used in Immunohistochemistry to create an excisional wound healing model in diabetic mice with renal dysfunction to investigate the combined effects of diabetes and nephropathy on cutaneous ulcers.
Tue Jan 01 00:00:00 EST 2019
Resveratrol Promotes Mitochondrial Biogenesis and Protects against Seizure-Induced Neuronal Cell Damage in the Hippocampus Following Status Epilepticus by Activation of the PGC-1α Signaling Pathway.
International journal of molecular sciences
Chuang YC,Chen SD,Hsu CY,Chen SF,Chen NC,Jou SB
A-21285 was used in Western Blotting to examine the neuroprotective effect of resveratrol on mitochondrial biogenesis in the hippocampus following experimental status epilepticus.
Mon Feb 25 00:00:00 EST 2019
Inhibition of EZH2 methyltransferase decreases immunoediting of mesothelioma cells by autologous macrophages through a PD-1-dependent mechanism.
JCI insight
Hamaidia M,Gazon H,Hoyos C,Hoffmann GB,Louis R,Duysinx B,Willems L
A-21285 was used in Immunohistochemistry to investigate direct macrophage cytotoxicity in malignant pleural mesothelioma.
Thu Sep 19 00:00:00 EDT 2019
TFEB-driven lysosomal biogenesis is pivotal for PGC1α-dependent renal stress resistance.
JCI insight
Lynch MR,Tran MT,Ralto KM,Zsengeller ZK,Raman V,Bhasin SS,Sun N,Chen X,Brown D,Rovira II,Taguchi K,Brooks CR,Stillman IE,Bhasin MK,Finkel T,Parikh SM
A-21285 was used in Immunohistochemistry to study the role of proliferator gamma coactivator 1-alpha in renal stress resistance.
Thu Mar 14 00:00:00 EDT 2019
Mitochondrial uncoupling prodrug improves tissue sparing, cognitive outcome, and mitochondrial bioenergetics after traumatic brain injury in male mice.
Journal of neuroscience research
Hubbard WB,Harwood CL,Geisler JG,Vekaria HJ,Sullivan PG
A-21285 was used in Western Blotting to study the use of MP201 to alleviate negative outcomes in traumatic brain injury.
Mon Oct 01 00:00:00 EDT 2018
Ceruloplasmin Plays a Neuroprotective Role in Cerebral Ischemia.
Frontiers in neuroscience
Ryan F,Zarruk JG,Lößlein L,David S
A-21285 was used in Immunohistochemistry to assess the role of ceruloplasmin in permanent middle cerebral artery occlusion, comparing wildtype and ceruloplasmin null mice.
Wed Sep 30 00:00:00 EDT 2020
Nitration of MnSOD in the Carotid Body and Adrenal Gland Induced by Chronic Intermittent Hypoxia.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society
Moya EA,Arias P,Iturriaga R
A-21285 was used in Western Blotting to show that CIH for 7 days produced MnSOD nitration, but failed to reduce its activity in the CB, because of the increased protein level.
Mon Oct 01 00:00:00 EDT 2018
Mycobacteria exploit nitric oxide-induced transformation of macrophages into permissive giant cells.
EMBO reports
Gharun K,Senges J,Seidl M,Lösslein A,Kolter J,Lohrmann F,Fliegauf M,Elgizouli M,Alber M,Vavra M,Schachtrup K,Illert AL,Gilleron M,Kirschning CJ,Triantafyllopoulou A,Henneke P
Published figure using Nitrotyrosine polyclonal antibody (Product # A-21285) in Immunohistochemistry
Fri Dec 01 00:00:00 EST 2017
Mitochondria-targeted antioxidant Mito-Tempo protects against acetaminophen hepatotoxicity.
Archives of toxicology
Du K,Farhood A,Jaeschke H
A-21285 was used in immunohistochemistry - paraffin section to learn about protection against acetaminophen hepatotoxicity by mitochondria-targeted antioxidant Mito-Tempo
Wed Feb 01 00:00:00 EST 2017
Oxidative stress and cellular and tissue damage in organogenic outbred mouse embryos after moderate perigestational alcohol intake.
Molecular reproduction and development
Coll TA,Chaufan G,Pérez-Tito L,Ventureira MR,Sobarzo CMA,Ríos de Molina MDC,Cebral E
Published figure using Nitrotyrosine polyclonal antibody (Product # A-21285) in Immunohistochemistry
Sun Oct 01 00:00:00 EDT 2017
Glutaminolysis is Essential for Energy Production and Ion Transport in Human Corneal Endothelium.
EBioMedicine
Zhang W,Li H,Ogando DG,Li S,Feng M,Price FW,Tennessen JM,Bonanno JA
Published figure using Nitrotyrosine polyclonal antibody (Product # A-21285) in Immunofluorescence
Wed Feb 01 00:00:00 EST 2017
Soluble fms-like tyrosine kinase 1 promotes angiotensin II sensitivity in preeclampsia.
The Journal of clinical investigation
Burke SD,Zsengellér ZK,Khankin EV,Lo AS,Rajakumar A,DuPont JJ,McCurley A,Moss ME,Zhang D,Clark CD,Wang A,Seely EW,Kang PM,Stillman IE,Jaffe IZ,Karumanchi SA
Published figure using Nitrotyrosine polyclonal antibody (Product # A-21285) in Immunohistochemistry
Fri Jul 01 00:00:00 EDT 2016
Intermittent Hypoxia-Induced Carotid Body Chemosensory Potentiation and Hypertension Are Critically Dependent on Peroxynitrite Formation.
Oxidative medicine and cellular longevity
Moya EA,Arias P,Varela C,Oyarce MP,Del Rio R,Iturriaga R
A-21285 was used in immunohistochemistry - paraffin section to determine the critical dependence on peroxynitrite formation for intermittent hypoxia-induced carotid body chemosensory potentiation and hypertension
Tue Dec 13 00:00:00 EST 2016
Oxidative stress augments chemoreflex sensitivity in rats exposed to chronic intermittent hypoxia.
Respiratory physiology & neurobiology
Morgan BJ,Bates ML,Rio RD,Wang Z,Dopp JM
A21285 was used in immunohistochemistry - paraffin section to test if chronic exposure to intermittent hypoxia-induced alterations in ventilation, metabolism, and heart rate are dependent on reactive oxygen species
Thu Dec 01 00:00:00 EST 2016
Administration of umbilical cord blood cells transiently decreased hypoxic-ischemic brain injury in neonatal rats.
Developmental neuroscience
Hattori T,Sato Y,Kondo T,Ichinohashi Y,Sugiyama Y,Yamamoto M,Kotani T,Hirata H,Hirakawa A,Suzuki S,Tsuji M,Ikeda T,Nakanishi K,Kojima S,Blomgren K,Hayakawa M
A-21285 was used in Immunohistochemistry to investigate whether the administration of human umbilical cord blood cells could ameliorate hypoxic-ischemic brain injury in a neonatal rat model.
Tue Jan 12 00:00:00 EST 2016
ESR and X-ray Structure Investigations on the Binding and Mechanism of Inhibition of the Native State of Myeloperoxidase with Low Molecular Weight Fragments.
Applied magnetic resonance
Chavali B,Masquelin T,Nilges MJ,Timm DE,Stout SL,Matter WF,Jin N,Jadhav PK,Deng GG
A-21285 was used in blocking assay to identify small molecules that inhibit myeloperoxidase.
Wed Sep 30 00:00:00 EDT 2020
Is L-methionine a trigger factor for Alzheimer's-like neurodegeneration?: Changes in Aβ oligomers, tau phosphorylation, synaptic proteins, Wnt signaling and behavioral impairment in wild-type mice.
Molecular neurodegeneration
Tapia-Rojas C,Lindsay CB,Montecinos-Oliva C,Arrazola MS,Retamales RM,Bunout D,Hirsch S,Inestrosa NC
A-21285 was used in immunohistochemistry and western blot to study Alzheimer's-like neurodegeneration by L-methionine by looking at changes in A-beta oligomers, synaptic proteins, Wnt signaling, tau phosphorylation, and behavioral impairment in wild-type
Sat Nov 21 00:00:00 EST 2015
Real-time imaging of oxidative and nitrosative stress in the liver of live animals for drug-toxicity testing.
Nature biotechnology
Shuhendler AJ,Pu K,Cui L,Uetrecht JP,Rao J
Published figure using Nitrotyrosine polyclonal antibody (Product # A-21285) in Immunohistochemistry
Tue Apr 01 00:00:00 EDT 2014
Nitroso-redox balance and mitochondrial homeostasis are regulated by STOX1, a pre-eclampsia-associated gene.
Antioxidants & redox signaling
Doridot L,Châtre L,Ducat A,Vilotte JL,Lombès A,Méhats C,Barbaux S,Calicchio R,Ricchetti M,Vaiman D
Published figure using Nitrotyrosine polyclonal antibody (Product # A-21285) in Immunofluorescence
Wed Aug 20 00:00:00 EDT 2014
Homocysteine disrupts outgrowth of microvascular endothelium by an iNOS-dependent mechanism.
Microcirculation (New York, N.Y. : 1994)
Mayo JN,Chen CH,Liao FF,Bearden SE
A-21285 was used in immunohistochemistry to test if Hcy impairs angiogenic outgrowth through an iNOS-dependent mechanism.
Fri Aug 01 00:00:00 EDT 2014
A common fungal volatile organic compound induces a nitric oxide mediated inflammatory response in Drosophila melanogaster.
Scientific reports
Inamdar AA,Bennett JW
A-21285 was used in immunohistochemistry to use fruit flies to study 1-octen-3-ol-mediated toxicity
Mon Feb 10 00:00:00 EST 2014
S-nitroso-N-acetylcysteine attenuates liver fibrosis in experimental nonalcoholic steatohepatitis.
Drug design, development and therapy
Mazo DF,de Oliveira MG,Pereira IV,Cogliati B,Stefano JT,de Souza GF,Rabelo F,Lima FR,Ferreira Alves VA,Carrilho FJ,de Oliveira CP
Published figure using Nitrotyrosine polyclonal antibody (Product # A-21285) in Immunohistochemistry
Tue Nov 26 00:00:00 EST 2013
Nitrative stress in cerebral endothelium is mediated by mGluR5 in hyperhomocysteinemia.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism
Mayo JN,Beard RS,Price TO,Chen CH,Erickson MA,Ercal N,Banks WA,Bearden SE
A-21285 was used in western blot to elucidate how extracellular homocysteine generates intracellular nitrotyrosinylation.
Tue May 01 00:00:00 EDT 2012
Smoking, COPD, and 3-nitrotyrosine levels of plasma proteins.
Environmental health perspectives
Jin H,Webb-Robertson BJ,Peterson ES,Tan R,Bigelow DJ,Scholand MB,Hoidal JR,Pounds JG,Zangar RC
Published figure using Nitrotyrosine polyclonal antibody (Product # A-21285) in ELISA
Thu Sep 01 00:00:00 EDT 2011
Infrarenal aortic-clamping after renal ischaemia aggravates acute renal failure.
European journal of clinical investigation
Yeung KK,Richir M,Hanrath P,Teerlink T,Kompanowska-Jezierska E,Musters RJ,van Leeuwen PA,Wisselink W,Tangelder GJ
A-21285 was used in immunohistochemistry to test if infrarenal aortic-clamping causes additional renal damage during repair of juxtarenal abdominal aortic aneurysms.
Wed Jun 01 00:00:00 EDT 2011
Hypertonic saline and reduced peroxynitrite formation in experimental pancreatitis.
Clinics (Sao Paulo, Brazil)
Rios EC,Moretti AS,Velasco IT,Souza HP,Abatepaulo F,Soriano F
Published figure using Nitrotyrosine polyclonal antibody (Product # A-21285) in Immunohistochemistry
Thu Nov 10 00:00:00 EST 2011
Hypothermic renal perfusion during aortic surgery reduces the presence of lipocalin-2 and preserves renal extraction of dimethylarginines in rats.
American journal of physiology. Renal physiology
Yeung KK,De Gouyon Matignon C,Renwarin L,Tjon-A-Fat MR,Teerlink T,van Leeuwen PA,Musters RJ,Wisselink W,Tangelder GJ
A-21285 was used in immunohistochemistry to test if the protective effect of cold perfusion is associated with renal extraction of dimethylarginines.
Thu Dec 01 00:00:00 EST 2011
Carotid body and cardiorespiratory alterations in intermittent hypoxia: the oxidative link.
The European respiratory journal
Del Rio R,Moya EA,Iturriaga R
A-21285 was used in immunohistochemistry - paraffin section to test if antioxidants reduce sleep apnea-induced damage
Thu Jul 01 00:00:00 EDT 2010
Extracellular transsulfuration generates hydrogen sulfide from homocysteine and protects endothelium from redox stress.
American journal of physiology. Heart and circulatory physiology
Bearden SE,Beard RS,Pfau JC
A-21285 was used in ELISA to test if blood protects the endothelium from redox stress through transsulfuration
Mon Nov 01 00:00:00 EDT 2010
Pericyte contraction induced by oxidative-nitrative stress impairs capillary reflow despite successful opening of an occluded cerebral artery.
Nature medicine
Yemisci M,Gursoy-Ozdemir Y,Vural A,Can A,Topalkara K,Dalkara T
A-21285 was used in immunohistochemistry to study the role of ischemia in inducing sustained contraction of pericytes on microvessels in the intact mouse brain
Tue Sep 01 00:00:00 EDT 2009
Biologically distinct conformations of Bcl-x can be resolved using 2D isoelectric focusing.
Molecular immunology
Rockwell KR,Huber BT
A-21285 was used in western blot to investigate conformational changes of Bcl-x
Fri May 01 00:00:00 EDT 2009
Competitive immunoassays for simultaneous detection of metabolites and proteins using micromosaic patterning.
Analytical chemistry
Murphy BM,He X,Dandy D,Henry CS
A-21285 was used to develop a new micromosaic competitive immunoassay for the analysis of thyroxine, C-reactive protein, and 3-nitrotyrosine on a silicon nitride substrate
Tue Jan 15 00:00:00 EST 2008
Competitive immunoassays for simultaneous detection of metabolites and proteins using micromosaic patterning.
Analytical chemistry
Murphy BM,He X,Dandy D,Henry CS
A-21285 was used to develop a new micromosaic competitive immunoassay for the analysis of thyroxine, C-reactive protein, and 3-nitrotyrosine on a silicon nitride substrate
Tue Jan 15 00:00:00 EST 2008
The reactive nitrogen species peroxynitrite is a potent inhibitor of renal Na-K-ATPase activity.
American journal of physiology. Renal physiology
Reifenberger MS,Arnett KL,Gatto C,Milanick MA
A-21285 was used in western blot to examine the direct effects of peroxynitrite on Na-K-ATPase function
Wed Oct 01 00:00:00 EDT 2008
Circulating white blood cells and platelets amplify oxidative stress in heart failure.
Nature clinical practice. Cardiovascular medicine
Ijsselmuiden AJ,Musters RJ,de Ruiter G,van Heerebeek L,Alderse-Baas F,van Schilfgaarde M,Leyte A,Tangelder GJ,Laarman GJ,Paulus WJ
A-21285 was used in immunocytochemistry to investigate the role of white blood cells and platelets as mediators in congestive heart failure
Mon Dec 01 00:00:00 EST 2008
Correlative transmission microscopy: cytochemical localization and immunocytochemical localization in studies of oxidative and nitrosative stress.
Methods in molecular biology (Clifton, N.J.)
Ellis EA
A-21285 was used in immunocytochemistry to discuss detection of oxidative and nitrosative stress on the same slide
Wed Jan 07 00:00:00 EST 2009
Apoptosis-inducing factor is a major contributor to neuronal loss induced by neonatal cerebral hypoxia-ischemia.
Cell death and differentiation
Zhu C,Wang X,Huang Z,Qiu L,Xu F,Vahsen N,Nilsson M,Eriksson PS,Hagberg H,Culmsee C,Plesnila N,Kroemer G,Blomgren K
A-21285 was used in immunohistochemistry to characterize defects in harlequin mutant mice
Sun Apr 01 00:00:00 EDT 2007
X chromosome-linked inhibitor of apoptosis protein reduces oxidative stress after cerebral irradiation or hypoxia-ischemia through up-regulation of mitochondrial antioxidants.
The European journal of neuroscience
Zhu C,Xu F,Fukuda A,Wang X,Fukuda H,Korhonen L,Hagberg H,Lannering B,Nilsson M,Eriksson PS,Northington FJ,Björk-Eriksson T,Lindholm D,Blomgren K
A-21285 was used in immunohistochemistry - paraffin section to determine that X chromosome-linked inhibitor of apoptosis protein counteracts oxidative stress in two disease-related models of brain injury
Sat Dec 01 00:00:00 EST 2007
The influence of age on apoptotic and other mechanisms of cell death after cerebral hypoxia-ischemia.
Cell death and differentiation
Zhu C,Wang X,Xu F,Bahr BA,Shibata M,Uchiyama Y,Hagberg H,Blomgren K
A-21285 was used in immunohistochemistry - paraffin section to report the developmental regulation of AIF-mediated cell death and involvement of autophagy in a brain injury model
Tue Feb 01 00:00:00 EST 2005
Beta2-agonist administration increases sarcoplasmic reticulum Ca2+-ATPase activity in aged rat skeletal muscle.
American journal of physiology. Endocrinology and metabolism
Schertzer JD,Plant DR,Ryall JG,Beitzel F,Stupka N,Lynch GS
A-21285 was used in western blot to test if fenoterol alters sarcoplasmic reticulum proteins in aging rats
Tue Mar 01 00:00:00 EST 2005
Age-dependent sensitivity of the developing brain to irradiation is correlated with the number and vulnerability of progenitor cells.
Journal of neurochemistry
Fukuda A,Fukuda H,Swanpalmer J,Hertzman S,Lannering B,Marky I,Björk-Eriksson T,Blomgren K
A-21285 was used in immunohistochemistry - paraffin section to compare the outcome after irradiation treatment in the immature and juvenile rat brain.
Tue Feb 01 00:00:00 EST 2005
Progenitor cell injury after irradiation to the developing brain can be modulated by mild hypothermia or hyperthermia.
Journal of neurochemistry
Fukuda A,Fukuda H,Jönsson M,Swanpalmer J,Hertzman S,Lannering B,Björk-Eriksson T,Màrky I,Blomgren K
A-21285 was used in western blot to investigate the effects of hypothermia and hyperthermia after irradiation in rats.
Thu Sep 01 00:00:00 EDT 2005
Irradiation-induced progenitor cell death in the developing brain is resistant to erythropoietin treatment and caspase inhibition.
Cell death and differentiation
Fukuda H,Fukuda A,Zhu C,Korhonen L,Swanpalmer J,Hertzman S,Leist M,Lannering B,Lindholm D,Björk-Eriksson T,Marky I,Blomgren K
A-21285 was used in immunohistochemistry - paraffin section to characterize irradiated-induced changes in postnatal rats and mice
Mon Nov 01 00:00:00 EST 2004
Role of oxidative stress and nitric oxide in regulation of spontaneous tone in aorta of DOCA-salt hypertensive rats.
British journal of pharmacology
Ghosh M,Wang HD,McNeill JR
A-21285 was used in immunohistochemistry - frozen section to study the roles of nitric oxide, superoxide anion, and hydrogen peroxide in the aorta of deoxycorticosterone acetate-treated hypertensive rats
Sun Feb 01 00:00:00 EST 2004
Effects of n-acetylcysteine in a rat model of ischemia and reperfusion injury.
Cardiovascular research
Cuzzocrea S,Mazzon E,Costantino G,Serraino I,De Sarro A,Caputi AP
A-21285 was used in immunohistochemistry to evaluate the effects of n-acetylcysteine in rats subjected to splanchnic artery occlusion shock
Fri Aug 18 00:00:00 EDT 2000
Peroxynitrite formation and decreased catalase activity in autoimmune MRL-lpr/lpr mice.
Molecular medicine (Cambridge, Mass.)
Keng T,Privalle CT,Gilkeson GS,Weinberg JB
A-21285 was used in western blot to assess the role of peroxynitrite in disease development in MRL-lpr/lpr mice
Fri Sep 01 00:00:00 EDT 2000
Widespread nitration of pathological inclusions in neurodegenerative synucleinopathies.
The American journal of pathology
Duda JE,Giasson BI,Chen Q,Gur TL,Hurtig HI,Stern MB,Gollomp SM,Ischiropoulos H,Lee VM,Trojanowski JQ
A-21285 was used in immunohistochemistry - paraffin section and western blot to determine the presence of nitrated alpha-synuclein in pathological lesions
Wed Nov 01 00:00:00 EST 2000
The tyrosine kinase inhibitor tyrphostin AG 126 reduced the development of colitis in the rat.
Laboratory investigation; a journal of technical methods and pathology
Cuzzocrea S,McDonald MC,Mazzon E,Mota-Filipe H,Lepore V,Ciccolo A,Terranova ML,Britti D,Caputi AP,Thiemermann C
A-21285 was used in immunohistochemistry - frozen section to assess the effects of Tyrphostin AG 126 in rats subjected to experimental colitis
Fri Sep 01 00:00:00 EDT 2000
Nitrotyrosine formation and its role in various pathological conditions.
Free radical research
Nakazawa H,Fukuyama N,Takizawa S,Tsuji C,Yoshitake M,Ishida H
A-21285 was used in immunohistochemistry to examine the formation of peroxynitrite and nitrotyrosine in a variety of animal models and determine their relationship to cell or tissue damage
Fri Dec 01 00:00:00 EST 2000
Incorporation of nitrotyrosine into alpha-tubulin by recombinant mammalian tubulin-tyrosine ligase.
Biochimica et biophysica acta
Kalisz HM,Erck C,Plessmann U,Wehland J
A-21285 was used in western blot to clone and characterize tubulin-tyrosine ligase from the porcine brain
Thu Aug 31 00:00:00 EDT 2000
Inhibition of amiloride-sensitive sodium-channel activity in distal lung epithelial cells by nitric oxide.
The American journal of physiology
Ding JW,Dickie J,O'Brodovich H,Shintani Y,Rafii B,Hackam D,Marunaka Y,Rotstein OD
A-21285 was used in immunocytochemistry to assess the ability of activated macrophages to modulate the bioelectric properties of distal lung epithelial cells
Sun Mar 01 00:00:00 EST 1998
Formation of nitrosyl hemoglobin and nitrotyrosine during murine leishmaniasis.
Photochemistry and photobiology
Giorgio S,Linares E,Capurro Mde L,de Bianchi AG,Augusto O
A-21285 was used in western blot to report that peroxynitrite forms during murine leishmaniasis and could result in aggravation of disease
Sat Jun 01 00:00:00 EDT 1996
.jpg?time=20220826)
.jpg?time=20220826)
.jpg?time=20220826?time=20220826 "Nitrotyrosine Antibody (A-21285) in ICC/IF")
.jpg?time=20220826?time=20220826 "Nitrotyrosine Antibody (A-21285) in IHC (P)")
