Product References
Protocol for PPP1R15A-inhibited mouse model establishment with subcutaneous B16F1 tumor and single-cell analysis.
STAR protocols
Wang R,Wang M,Pei S,Zhang Y,Guo S,Guo W,Wu Z,Wang H,Li Y,Zhu Y,Meng LH,Lang J,Jin G,Xiao Y,Hu L,Kong X
Published figure using NK1.1 monoclonal antibody (Product # 17-5941-82) in Flow Cytometry
Fri Dec 15 00:00:00 EST 2023
MCL-1 Inhibitor S63845 Distinctively Affects Intramedullary and Extramedullary Hematopoiesis.
Pharmaceutics
Zhang H,Li F,Yang M,Zhang W,He M,Xu H,Wang C,Zhang Y,Wang W,Gao Y,Du X,Li Y
Published figure using NK1.1 monoclonal antibody (Product # 17-5941-82) in Flow Cytometry
Tue Mar 28 00:00:00 EDT 2023
Mesenchymal stromal cells equipped by IFNα empower T cells with potent anti-tumor immunity.
Oncogene
Zhang T,Wang Y,Li Q,Lin L,Xu C,Xue Y,Hu M,Shi Y,Wang Y
17-5941-82 was used in Flow Cytometry to conclude that IFNα-MSCs represent a novel tumor immunotherapy strategy, especially when combined with PD-L1 blockade.
Tue Mar 01 00:00:00 EST 2022
Peripheral Neutrophils-Derived Matrix Metallopeptidase-9 Induces Postoperative Cognitive Dysfunction in Aged Mice.
Frontiers in aging neuroscience
Huang L,Tian W,Chen X,Xu H,Dai W,Zhang Y,Wu X,Yu W,Tian J,Su D
Published figure using NK1.1 monoclonal antibody (Product # 17-5941-82) in Flow Cytometry
Mon Mar 14 00:00:00 EDT 2022
NK cells require immune checkpoint receptor LILRB4/gp49B to control neurotropic Zika virus infections in mice.
JCI insight
Lee HN,Manangeeswaran M,Lewkowicz AP,Engel K,Chowdhury M,Garige M,Eckhaus MA,Sourbier C,Ireland DD,Verthelyi D
Published figure using NK1.1 monoclonal antibody (Product # 17-5941-82) in Flow Cytometry
Tue Feb 08 00:00:00 EST 2022
Valosin-containing protein (VCP/p97) inhibition reduces viral clearance and induces toxicity associated with muscular damage.
Cell death & disease
Del Rio Oliva M,Basler M
17-5941-82 was used in Flow Cytometry to evaluate the effect of CB-5083 on the immune response in mice by using the lymphocytic choriomeningitis virus (LCMV) as an infection model.
Thu Dec 01 00:00:00 EST 2022
Valosin-containing protein (VCP/p97) inhibition reduces viral clearance and induces toxicity associated with muscular damage.
Cell death & disease
Del Rio Oliva M,Basler M
17-5941-82 was used in Flow Cytometry to evaluate the effect of CB-5083 on the immune response in mice by using the lymphocytic choriomeningitis virus (LCMV) as an infection model.
Thu Dec 01 00:00:00 EST 2022
ZhenQi FuZheng formula inhibits the growth of colorectal tumors by modulating intestinal microflora-mediated immune function.
Aging
Meng W,Li Z,Zhang Y,Yang A,Wang Y,Zhou Y,Wu W,Qiu Y,Li L
17-5941-82 was used in Flow cytometry/Cell sorting to provide the experimental basis for the application of ZQFZ as a therapeutic agent for CRC.
Wed Jun 08 00:00:00 EDT 2022
Meningeal lymphatic drainage promotes T cell responses against Toxoplasma gondii but is dispensable for parasite control in the brain.
eLife
Kovacs MA,Cowan MN,Babcock IW,Sibley LA,Still K,Batista SJ,Labuzan SA,Sethi I,Harris TH
17-5941-82 was used in Flow cytometry/Cell sorting to reveal that CNS lymphatic drainage supports the development of peripheral T cell responses against T. gondii but remains dispensable for immune protection of the brain.
Wed Dec 21 00:00:00 EST 2022
Tumor necrosis factor receptor superfamily member 25 (TNFRSF25) agonists in islet transplantation: Endogenous in vivo regulatory T cell expansion promotes prolonged allograft survival.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons
Marfil-Garza BA,Pawlick RL,Szeto J,Kroger C,Tahiliani V,Hefler J,Dadheech N,Seavey MM,Wolf J,Jasuja RR,James Shapiro AM
17-5941-82 was used in Flow cytometry/Cell sorting to explore endogenous in vivo Treg expansion through antibody-mediated agonistic stimulation of the tumor necrosis factor receptor superfamily member 25 (TNFRSF25) pathway and its potential to prolong graft survival in a mouse model of islet allotransplantation.
Fri Apr 01 00:00:00 EDT 2022
Therapeutic inhibition of the SRC-kinase HCK facilitates T cell tumor infiltration and improves response to immunotherapy.
Science advances
Poh AR,Love CG,Chisanga D,Steer JH,Baloyan D,Chopin M,Nutt S,Rautela J,Huntington ND,Etemadi N,O'Brien M,O'Keefe R,Ellies LG,Macri C,Mintern JD,Whitehead L,Gangadhara G,Boon L,Chand AL,Lowell CA,Shi W,Pixley FJ,Ernst M
17-5941-82 was used in Flow cytometry/Cell sorting to suggest that therapeutic targeting of HCK activity enhances response to immunotherapy by simultaneously stimulating immune cell activation and inhibiting the immunosuppressive tumor microenvironment.
Fri Jun 24 00:00:00 EDT 2022
The transcriptional repressor ID2 supports natural killer cell maturation by controlling TCF1 amplitude.
The Journal of experimental medicine
Li ZY,Morman RE,Hegermiller E,Sun M,Bartom ET,Maienschein-Cline M,Sigvardsson M,Kee BL
17-5941-82 was used in Flow Cytometry to demonstrate that ID2 sets a threshold for TCF1 during NK cell development, thus controlling the balance of immature and terminally differentiated cells that support future NK cell responses.
Mon Jun 07 00:00:00 EDT 2021
The transcriptional repressor ID2 supports natural killer cell maturation by controlling TCF1 amplitude.
The Journal of experimental medicine
Li ZY,Morman RE,Hegermiller E,Sun M,Bartom ET,Maienschein-Cline M,Sigvardsson M,Kee BL
17-5941-82 was used in Flow Cytometry to demonstrate that ID2 sets a threshold for TCF1 during NK cell development, thus controlling the balance of immature and terminally differentiated cells that support future NK cell responses.
Mon Jun 07 00:00:00 EDT 2021
Chronic T cell proliferation in brains after stroke could interfere with the efficacy of immunotherapies.
The Journal of experimental medicine
Heindl S,Ricci A,Carofiglio O,Zhou Q,Arzberger T,Lenart N,Franzmeier N,Hortobagyi T,Nelson PT,Stowe AM,Denes A,Edbauer D,Liesz A
Published figure using NK1.1 monoclonal antibody (Product # 17-5941-82) in Flow Cytometry
Mon Aug 02 00:00:00 EDT 2021
Neu-P11 - a novel melatonin receptor agonist, could improve the features of type-2 diabetes mellitus in rats.
Endokrynologia Polska
Li X,He J,Li X,Li Y,Zhou Y,Cai S
17-5941-82 was used in Flow Cytometry to investigate the effects of melatonin receptor agonist Neu-P11 on glucose metabolism, immunity, and islet function in type 2 diabetes mellitus rats.
Mon Mar 28 00:00:00 EDT 2022
Exosomal lncRNA SNHG10 derived from colorectal cancer cells suppresses natural killer cell cytotoxicity by upregulating INHBC.
Cancer cell international
Huang Y,Luo Y,Ou W,Wang Y,Dong D,Peng X,Luo Y
Published figure using NK1.1 monoclonal antibody (Product # 17-5941-82) in Flow Cytometry
Tue Oct 12 00:00:00 EDT 2021
Expression of CCRL2 Inhibits Tumor Growth by Concentrating Chemerin and Inhibiting Neoangiogenesis.
Cancers
Al Delbany D,Robert V,Dubois-Vedrenne I,Del Prete A,Vernimmen M,Radi A,Lefort A,Libert F,Wittamer V,Sozzani S,Parmentier M
Published figure using NK1.1 monoclonal antibody (Product # 17-5941-82) in Flow Cytometry
Tue Oct 05 00:00:00 EDT 2021
Near-infrared photoimmunotherapy targeting human-EGFR in a mouse tumor model simulating current and future clinical trials.
EBioMedicine
Okada R,Furusawa A,Vermeer DW,Inagaki F,Wakiyama H,Kato T,Nagaya T,Choyke PL,Spanos WC,Allen CT,Kobayashi H
Published figure using NK1.1 monoclonal antibody (Product # 17-5941-82) in Flow Cytometry
Sat May 01 00:00:00 EDT 2021
A novel miR1983-TLR7-IFNβ circuit licenses NK cells to kill glioma cells, and is under the control of galectin-1.
Oncoimmunology
Shah D,Comba A,Faisal SM,Kadiyala P,Baker GJ,Alghamri MS,Doherty R,Zamler D,Nuñez G,Castro MG,Lowenstein PR
Published figure using NK1.1 monoclonal antibody (Product # 17-5941-82) in Flow Cytometry
Mon Aug 02 00:00:00 EDT 2021
USP12 downregulation orchestrates a protumourigenic microenvironment and enhances lung tumour resistance to PD-1 blockade.
Nature communications
Yang Z,Xu G,Wang B,Liu Y,Zhang L,Jing T,Tang M,Xu X,Jiao K,Xiang L,Fu Y,Tang D,Zhang X,Jin W,Zhuang G,Zhao X,Liu Y
17-5941-82 was used in Flow Cytometry to show that the deubiquitinase USP12 is commonly downregulated in the KrasG12D-driven mouse lung tumour and human non-small cell lung cancer owing to the activation of AKT-mTOR signalling.
Wed Aug 11 00:00:00 EDT 2021
Sequencing, cloning, and antigen binding analysis of monoclonal antibodies isolated from single mouse B cells.
STAR protocols
Viant C,Escolano A,Chen ST,Nussenzweig MC
Published figure using NK1.1 monoclonal antibody (Product # 17-5941-82) in Flow Cytometry
Fri Jun 18 00:00:00 EDT 2021
The enrichment of neutrophil extracellular traps impair the placentas of systemic lupus erythematosus through accumulating decidual NK cells.
Scientific reports
Jiang M,Shen N,Zhou H,Wang Y,Lin S,Wu J,Di W
Published figure using NK1.1 monoclonal antibody (Product # 17-5941-82) in Flow Cytometry
Thu Mar 25 00:00:00 EDT 2021
Placenta-Expanded Stromal Cell Therapy in a Rodent Model of Simulated Weightlessness.
Cells
Rubinstein L,Paul AM,Houseman C,Abegaz M,Tabares Ruiz S,O'Neil N,Kunis G,Ofir R,Cohen J,Ronca AE,Globus RK,Tahimic CGT
17-5941-82 was used in Flow Cytometry to support the therapeutic potential of placenta-derived stromal cells for select physiological deficits during simulated spaceflight.
Mon Apr 19 00:00:00 EDT 2021
Serum Amyloid A Proteins Induce Pathogenic Th17 Cells and Promote Inflammatory Disease.
Cell
Lee JY,Hall JA,Kroehling L,Wu L,Najar T,Nguyen HH,Lin WY,Yeung ST,Silva HM,Li D,Hine A,Loke P,Hudesman D,Martin JC,Kenigsberg E,Merad M,Khanna KM,Littman DR
17-5941 was used in Flow cytometry/Cell sorting to suggest that serum amyloid A proteins direct a pathogenic pro-inflammatory Th17 cell differentiation program and promote Th17-mediated inflammatory diseases.
Thu Jan 09 00:00:00 EST 2020
IL-13 Ameliorates Neuroinflammation and Promotes Functional Recovery after Traumatic Brain Injury.
Journal of immunology (Baltimore, Md. : 1950)
Miao W,Zhao Y,Huang Y,Chen D,Luo C,Su W,Gao Y
17-5941 was used in Flow cytometry/Cell sorting to demonstrate that IL-13 treatment improved neurologic outcomes after Traumatic Brain Injury through adjusting microglia/macrophage phenotypes and inhibiting inflammatory responses.
Sun Mar 15 00:00:00 EDT 2020
Identification of atypical mitogen-activated protein kinase MAPK4 as a novel regulator in acute lung injury.
Cell & bioscience
Mao L,Zhou Y,Chen L,Hu L,Liu S,Zheng W,Zhao J,Guo M,Chen C,He Z,Xu L
17-5941-82 was used in Flow Cytometry to reveal an unknown role of atypical MAPKs member MAPK4 in the pathology of acute lung injury.
Sun Apr 17 00:00:00 EDT 2022
Analysis of Myeloid Cells in Mouse Tissues with Flow Cytometry.
STAR protocols
Liu Z,Gu Y,Shin A,Zhang S,Ginhoux F
Published figure using NK1.1 monoclonal antibody (Product # 17-5941-82) in Flow Cytometry
Fri Jun 19 00:00:00 EDT 2020
TLR9 Sensing of Self-DNA Controls Cell-Mediated Immunity to Listeria Infection via Rapid Conversion of Conventional CD4+ T Cells to Treg.
Cell reports
Dolina JS,Lee J,Griswold RQ,Labarta-Bajo L,Kannan S,Greenbaum JA,Bahia El Idrissi N,Pont MJ,Croft M,Schoenberger SP
17-5941 was used in Flow cytometry/Cell sorting to resolve long-standing questions regarding the conditional requirement for TH amongst pathogens and reveal a remarkable degree of plasticity in the function of CD4+ T cells, which can be quickly converted to Tregin vivo by infection-mediated immune modulation.
Tue Apr 07 00:00:00 EDT 2020
Loss of testosterone impairs anti-tumor neutrophil function.
Nature communications
Markman JL,Porritt RA,Wakita D,Lane ME,Martinon D,Noval Rivas M,Luu M,Posadas EM,Crother TR,Arditi M
17-5941-82 was used in Flow cytometry/Cell sorting to show that in castrated male mice, neutrophil maturation and function are impaired, leading to elevated metastatic burden in two models of melanoma.
Tue Mar 31 00:00:00 EDT 2020
Dendritic Cells and Myeloid Derived Suppressor Cells Fully Responsive to Stimulation via Toll-Like Receptor 4 Are Rapidly Induced from Bone-Marrow Cells by Granulocyte-Macrophage Colony-Stimulating Factor.
Vaccines
Kong YY,Wilson K,Apostolopoulos V,Plebanski M
Published figure using NK1.1 monoclonal antibody (Product # 17-5941-82) in Flow Cytometry
Sat Sep 12 00:00:00 EDT 2020
Prodrug-Loaded Zirconium Carbide Nanosheets as a Novel Biophotonic Nanoplatform for Effective Treatment of Cancer.
Advanced science (Weinheim, Baden-Wurttemberg, Germany)
Liu Q,Xie Z,Qiu M,Shim I,Yang Y,Xie S,Yang Q,Wang D,Chen S,Fan T,Ding B,Guo Z,Adah D,Yao X,Zhang Y,Wu H,Wu Z,Wei C,Wang H,Kim HS,Zou Q,Yan Q,Cai Z,Kim JS,Liu LP,Zhang H,Cao Y
17-5941-82 was used in Flow Cytometry to unravel a promising biophotonic strategy for precision treatment of cancer.
Tue Dec 01 00:00:00 EST 2020
Manipulation of the tumor microenvironment by cytokine gene transfection enhances dendritic cell-based immunotherapy.
FASEB bioAdvances
Wijesekera DPH,Yuba E,De Silva NH,Watanabe SI,Tsukamoto M,Ichida C,Izawa T,Itoh K,Kanegi R,Hatoya S,Yamate J,Inaba T,Sugiura K
17-5941-82 was used in Flow Cytometry to manipulate the microenvironment so as to elicit activation of T helper type 1 (Th1) responses and the maturation of dendritic cells (DCs).
Wed Jan 01 00:00:00 EST 2020
Immunization expands B cells specific to HIV-1 V3 glycan in mice and macaques.
Nature
Escolano A,Gristick HB,Abernathy ME,Merkenschlager J,Gautam R,Oliveira TY,Pai J,West AP,Barnes CO,Cohen AA,Wang H,Golijanin J,Yost D,Keeffe JR,Wang Z,Zhao P,Yao KH,Bauer J,Nogueira L,Gao H,Voll AV,Montefiori DC,Seaman MS,Gazumyan A,Silva M,McGuire AT,Stamatatos L,Irvine DJ,Wells L,Martin MA,Bjorkman PJ,Nussenzweig MC
Published figure using NK1.1 monoclonal antibody (Product # 17-5941-82) in Flow Cytometry
Sat Jun 01 00:00:00 EDT 2019
Characterization of Transcriptional Regulatory Networks that Promote and Restrict Identities and Functions of Intestinal Innate Lymphoid Cells.
Immunity
Pokrovskii M,Hall JA,Ochayon DE,Yi R,Chaimowitz NS,Seelamneni H,Carriero N,Watters A,Waggoner SN,Littman DR,Bonneau R,Miraldi ER
17-5941 was used in Flow cytometry/Cell sorting to study regulatory interactions between transcription factors and genes within intestinal type 1, 2, and 3 innate lymphoid cells subsets.
Tue Jul 16 00:00:00 EDT 2019
Cell-intrinsic depletion of Aml1-ETO-expressing pre-leukemic hematopoietic stem cells by K-Ras activating mutation.
Haematologica
Di Genua C,Norfo R,Rodriguez-Meira A,Wen WX,Drissen R,Booth CAG,Povinelli B,Repapi E,Gray N,Carrelha J,Kettyle LM,Jamieson L,Neo WH,Thongjuea S,Nerlov C,Mead AJ
17-5941 was used in Flow cytometry/Cell sorting to study the mechanism behind absence of KRAS signalling mutations in pre-malignant hematopoietic stem cell compartments.
Fri Nov 01 00:00:00 EDT 2019
Synergized regulation of NK cell education by NKG2A and specific Ly49 family members.
Nature communications
Zhang X,Feng J,Chen S,Yang H,Dong Z
Published figure using NK1.1 monoclonal antibody (Product # 17-5941-82) in Flow Cytometry
Fri Nov 01 00:00:00 EDT 2019
Progranulin prevents regulatory NK cell cytotoxicity against antiviral T cells.
JCI insight
Huang A,Shinde PV,Huang J,Senff T,Xu HC,Margotta C,Häussinger D,Willnow TE,Zhang J,Pandyra AA,Timm J,Weggen S,Lang KS,Lang PA
Published figure using NK1.1 monoclonal antibody (Product # 17-5941-82) in Flow Cytometry
Thu Sep 05 00:00:00 EDT 2019
Antitumor immunity augments the therapeutic effects of p53 activation on acute myeloid leukemia.
Nature communications
Hayashi Y,Goyama S,Liu X,Tamura M,Asada S,Tanaka Y,Fukuyama T,Wunderlich M,O'Brien E,Mizukawa B,Yamazaki S,Matsumoto A,Yamasaki S,Shibata T,Matsuda K,Sashida G,Takizawa H,Kitamura T
Published figure using NK1.1 monoclonal antibody (Product # 17-5941-82) in Flow Cytometry
Fri Oct 25 00:00:00 EDT 2019
Restricting Glycolysis Preserves T Cell Effector Functions and Augments Checkpoint Therapy.
Cell reports
Renner K,Bruss C,Schnell A,Koehl G,Becker HM,Fante M,Menevse AN,Kauer N,Blazquez R,Hacker L,Decking SM,Bohn T,Faerber S,Evert K,Aigle L,Amslinger S,Landa M,Krijgsman O,Rozeman EA,Brummer C,Siska PJ,Singer K,Pektor S,Miederer M,Peter K,Gottfried E,Herr W,Marchiq I,Pouyssegur J,Roush WR,Ong S,Warren S,Pukrop T,Beckhove P,Lang SA,Bopp T,Blank CU,Cleveland JL,Oefner PJ,Dettmer K,Selby M,Kreutz M
17-5941-82 was used in Flow Cytometry to report that melanoma patients with high expression of glycolysis-related genes show a worse progression free survival upon anti-PD1 treatment and support the rationale for targeting glycolysis in patients with high glycolytic tumors together with checkpoint inhibitors in clinical trials.
Tue Oct 01 00:00:00 EDT 2019
Deletion of C-C Motif Chemokine Ligand 5 Worsens Invariant Natural Killer T-Cell-Mediated Hepatitis via Compensatory Up-regulation of CXCR2-Related Chemokine Activity.
Cellular and molecular gastroenterology and hepatology
Chen L,Gu J,Qian Y,Li M,Qian Y,Xu M,Li J,Wen Y,Xia L,Li J,Xia Q,Kong X,Wu H
17-5941 was used in Flow cytometry/Cell sorting to demonstrate that the clinical use of blocking CCL5 may induce other chemokine signals such as CXCL1-CXCR2 to induce further enhanced hepatic infiltration of neutrophils.
Tue Jun 04 00:00:00 EDT 2019
Myeloid Cells Restrict MCMV and Drive Stress-Induced Extramedullary Hematopoiesis through STAT1.
Cell reports
Gawish R,Bulat T,Biaggio M,Lassnig C,Bago-Horvath Z,Macho-Maschler S,Poelzl A,Simonović N,Prchal-Murphy M,Rom R,Amenitsch L,Ferrarese L,Kornhoff J,Lederer T,Svinka J,Eferl R,Bosmann M,Kalinke U,Stoiber D,Sexl V,Krmpotić A,Jonjić S,Müller M,Strobl B
17-5941 was used in Flow cytometry/Cell sorting to provide genetic evidence that signaling through STAT1 in myeloid cells is required to restrict MCMV at early time points post-infection and to induce compensatory hematopoiesis in the spleen.
Tue Feb 26 00:00:00 EST 2019
Persistence of Integrase-Deficient Lentiviral Vectors Correlates with the Induction of STING-Independent CD8+ T Cell Responses.
Cell reports
Cousin C,Oberkampf M,Felix T,Rosenbaum P,Weil R,Fabrega S,Morante V,Negri D,Cara A,Dadaglio G,Leclerc C
17-5941 was used in Flow cytometry/Cell sorting to demonstrate that integrase-deficient lentiviral vectors can trigger persistent adaptive response by the mediation of a weak and transient innate response alongside the persistence of the vector in tissues.
Tue Jan 29 00:00:00 EST 2019
Modulation of autoimmune pathogenesis by T cell-triggered inflammatory cell death.
Nature communications
Sasaki K,Himeno A,Nakagawa T,Sasaki Y,Kiyonari H,Iwai K
17-5941-82 was used in Flow Cytometry to show that T cell-mediated killing and sequential autoinflammation are common and crucial for pathogenic diversity during T cell-mediated autoimmune responses.
Wed Aug 28 00:00:00 EDT 2019
Invariant natural killer T-cell development and function with loss of microRNA-155.
Immunology
Frias AB,Buechel HM,Neupane A,D'Cruz LM
17-5941 was used in Flow cytometry/Cell sorting to examine the role of microRNA-155 in the development and function of invariant natural killer T cells.
Thu Feb 01 00:00:00 EST 2018
CD8+ T cells mediate the antitumor activity of frankincense and myrrh in hepatocellular carcinoma.
Journal of translational medicine
Xu C,Lu X,Liu W,Chen A,Meng G,Zhang H,Li B,Zhang Y,Wu J,Wei J
Published figure using NK1.1 monoclonal antibody (Product # 17-5941-82) in Flow Cytometry
Mon May 21 00:00:00 EDT 2018
Plasmodium co-infection protects against chikungunya virus-induced pathologies.
Nature communications
Teo TH,Lum FM,Ghaffar K,Chan YH,Amrun SN,Tan JJL,Lee CYP,Chua TK,Carissimo G,Lee WWL,Claser C,Rajarethinam R,Rénia L,Ng LFP
Published figure using NK1.1 monoclonal antibody (Product # 17-5941-82) in Flow Cytometry
Tue Sep 25 00:00:00 EDT 2018
Inflammation caused by peripheral immune cells across into injured mouse blood brain barrier can worsen postoperative cognitive dysfunction induced by isoflurane.
BMC cell biology
Zhu H,Liu W,Fang H
17-5941 was used in Flow cytometry/Cell sorting to study the underlying mechanism by which blood-brain barrier disruption promotes postoperative cognitive dysfunction in the elderly population.
Sat Sep 29 00:00:00 EDT 2018
A stochastic epigenetic switch controls the dynamics of T-cell lineage commitment.
eLife
Ng KK,Yui MA,Mehta A,Siu S,Irwin B,Pease S,Hirose S,Elowitz MB,Rothenberg EV,Kueh HY
17-5941 was used in Flow cytometry/Cell sorting to study the activation of Bcl11b, which controls T-cell fate commitment.
Tue Nov 20 00:00:00 EST 2018
CRISPR/Cas9-mediated knockout of Rag-2 causes systemic lymphopenia with hypoplastic lymphoid organs in FVB mice.
Laboratory animal research
Kim JI,Park JS,Kim H,Ryu SK,Kwak J,Kwon E,Yun JW,Nam KT,Lee HW,Kang BC
17-5941 was used in Flow cytometry/Cell sorting to determine the role of recombination activating gene-2 in the development of lymphocytes.
Sat Dec 01 00:00:00 EST 2018
Regulatory Innate Lymphoid Cells Control Innate Intestinal Inflammation.
Cell
Wang S,Xia P,Chen Y,Qu Y,Xiong Z,Ye B,Du Y,Tian Y,Yin Z,Xu Z,Fan Z
17-5941 was used in Flow cytometry/Cell sorting to identify a regulatory subpopulation of innate lymphoid cells that exists in the gut, and harbour a unique gene identity.
Thu Sep 21 00:00:00 EDT 2017
Genomic Characterization of Murine Monocytes Reveals C/EBPβ Transcription Factor Dependence of Ly6C- Cells.
Immunity
Mildner A,Schönheit J,Giladi A,David E,Lara-Astiaso D,Lorenzo-Vivas E,Paul F,Chappell-Maor L,Priller J,Leutz A,Amit I,Jung S
17-5941-82 was used in Flow Cytometry to characterise the population and single cell transcriptomes, as well as enhancer and promoter landscapes of the murine monocyte compartment.
Tue May 16 00:00:00 EDT 2017
Differentiation of human and murine induced pluripotent stem cells to microglia-like cells.
Nature neuroscience
Pandya H,Shen MJ,Ichikawa DM,Sedlock AB,Choi Y,Johnson KR,Kim G,Brown MA,Elkahloun AG,Maric D,Sweeney CL,Gossa S,Malech HL,McGavern DB,Park JK
Published figure using NK1.1 monoclonal antibody (Product # 17-5941-82) in Flow Cytometry
Mon May 01 00:00:00 EDT 2017
A TLR7 agonist enhances the antitumor efficacy of obinutuzumab in murine lymphoma models via NK cells and CD4 T cells.
Leukemia
Cheadle EJ,Lipowska-Bhalla G,Dovedi SJ,Fagnano E,Klein C,Honeychurch J,Illidge TM
Published figure using NK1.1 monoclonal antibody (Product # 17-5941-82) in Flow Cytometry
Sat Jul 01 00:00:00 EDT 2017
MyD88 signaling in dendritic cells and the intestinal epithelium controls immunity against intestinal infection with C. rodentium.
PLoS pathogens
Friedrich C,Mamareli P,Thiemann S,Kruse F,Wang Z,Holzmann B,Strowig T,Sparwasser T,Lochner M
Mon May 01 00:00:00 EDT 2017
Retinoic Acid Regulates Immune Responses by Promoting IL-22 and Modulating S100 Proteins in Viral Hepatitis.
Journal of immunology (Baltimore, Md. : 1950)
Jie Z,Liang Y,Yi P,Tang H,Soong L,Cong Y,Zhang K,Sun J
Mon May 01 00:00:00 EDT 2017
IL-2/Anti-IL-2 Complex Attenuates Inflammation and BBB Disruption in Mice Subjected to Traumatic Brain Injury.
Frontiers in neurology
Gao W,Li F,Zhou Z,Xu X,Wu Y,Zhou S,Yin D,Sun D,Xiong J,Jiang R,Zhang J
Published figure using NK1.1 monoclonal antibody (Product # 17-5941-82) in Flow Cytometry
Thu Oct 01 00:00:00 EDT 2020
Loss of HIF-1α in natural killer cells inhibits tumour growth by stimulating non-productive angiogenesis.
Nature communications
Krzywinska E,Kantari-Mimoun C,Kerdiles Y,Sobecki M,Isagawa T,Gotthardt D,Castells M,Haubold J,Millien C,Viel T,Tavitian B,Takeda N,Fandrey J,Vivier E,Sexl V,Stockmann C
Published figure using NK1.1 monoclonal antibody (Product # 17-5941-82) in Flow Cytometry
Fri Nov 17 00:00:00 EST 2017
Immunomodulatory Effects of Adipose Tissue-Derived Stem Cells on Concanavalin A-Induced Acute Liver Injury in Mice.
Cell medicine
Yoshizumi Y,Yukawa H,Iwaki R,Fujinaka S,Kanou A,Kanou Y,Yamada T,Nakagawa S,Ohara T,Nakagiri K,Ogihara Y,Tsutsui Y,Hayashi Y,Ishigami M,Baba Y,Ishikawa T
17-5941 was used in Flow cytometry/Cell sorting to evaluate the therapeutic effects of adipose tissue-derived stem cells on fulminant hepatic failure.
Sun Jan 08 00:00:00 EST 2017
The breast tumor microenvironment alters the phenotype and function of natural killer cells.
Cellular & molecular immunology
Krneta T,Gillgrass A,Chew M,Ashkar AA
Published figure using NK1.1 monoclonal antibody (Product # 17-5941-82) in Flow Cytometry
Thu Sep 01 00:00:00 EDT 2016
The breast tumor microenvironment alters the phenotype and function of natural killer cells.
Cellular & molecular immunology
Krneta T,Gillgrass A,Chew M,Ashkar AA
Published figure using NK1.1 monoclonal antibody (Product # 17-5941-82) in Flow Cytometry
Thu Sep 01 00:00:00 EDT 2016
Resolving TYK2 locus genotype-to-phenotype differences in autoimmunity.
Science translational medicine
Dendrou CA,Cortes A,Shipman L,Evans HG,Attfield KE,Jostins L,Barber T,Kaur G,Kuttikkatte SB,Leach OA,Desel C,Faergeman SL,Cheeseman J,Neville MJ,Sawcer S,Compston A,Johnson AR,Everett C,Bell JI,Karpe F,Ultsch M,Eigenbrot C,McVean G,Fugger L
17-5941 was used in Flow cytometry/Cell sorting to reveal a protective homozygous effect that defined a signalling optimum between autoimmunity and immunodeficiency and identified TYK2 as a potential drug target for autoimmune disorders.
Wed Nov 02 00:00:00 EDT 2016
Hypoxia-Inducible Factor-2α Limits Natural Killer T Cell Cytotoxicity in Renal Ischemia/Reperfusion Injury.
Journal of the American Society of Nephrology : JASN
Zhang J,Han C,Dai H,Hou J,Dong Y,Cui X,Xu L,Zhang M,Xia Q
Fri Jan 01 00:00:00 EST 2016
Hypoxia-Inducible Factor-2α Limits Natural Killer T Cell Cytotoxicity in Renal Ischemia/Reperfusion Injury.
Journal of the American Society of Nephrology : JASN
Zhang J,Han C,Dai H,Hou J,Dong Y,Cui X,Xu L,Zhang M,Xia Q
Fri Jan 01 00:00:00 EST 2016
MicroRNA-7 Deficiency Ameliorates the Pathologies of Acute Lung Injury through Elevating KLF4.
Frontiers in immunology
Zhao J,Chen C,Guo M,Tao Y,Cui P,Zhou Y,Qin N,Zheng J,Zhang J,Xu L
17-5941 was used in Flow cytometry/Cell sorting to study the role of microRNA-7 in acute lung injury, allowing the development of new therapeutic strategies against inflammatory lung disease.
Wed Mar 16 00:00:00 EDT 2022
Lung epithelium and myeloid cells cooperate to clear acute pneumococcal infection.
Mucosal immunology
Dudek M,Puttur F,Arnold-Schrauf C,Kühl AA,Holzmann B,Henriques-Normark B,Berod L,Sparwasser T
17-5941 was used in Flow cytometry/Cell sorting to investigate the extent to which MyD88 signaling is required to control S. pneumoniae infection, showing that lung epithelium and myeloid cells cooperate to clear infection.
Thu Sep 01 00:00:00 EDT 2016
Trypanosoma brucei Co-opts NK Cells to Kill Splenic B2 B Cells.
PLoS pathogens
Frenkel D,Zhang F,Guirnalda P,Haynes C,Bockstal V,Radwanska M,Magez S,Black SJ
17-5941 was used in Flow cytometry/Cell sorting to investigate the mechanism by which natural killer cells in Trypanosoma brucei infected mice kill B cells, suppress humoral immunity and induce early mortality.
Fri Jul 01 00:00:00 EDT 2016
Id2 regulates hyporesponsive invariant natural killer T cells.
Immunology and cell biology
Stradner MH,Cheung KP,Lasorella A,Goldrath AW,D'Cruz LM
17-5941 was used in Flow cytometry/Cell sorting to propose that downregulation of Id2 expression is essential to induction of the anti-inflammatory state in iNKT cells.
Mon Aug 01 00:00:00 EDT 2016
Flow cytometric analysis of inflammatory and resident myeloid populations in mouse ocular inflammatory models.
Experimental eye research
Liyanage SE,Gardner PJ,Ribeiro J,Cristante E,Sampson RD,Luhmann UF,Ali RR,Bainbridge JW
17-5941 was used in Flow cytometry/Cell sorting to demonstrate a standardised method for the identification and quantification of myeloid cells in diseased tissues.
Sat Oct 01 00:00:00 EDT 2016
NK cell development requires Tsc1-dependent negative regulation of IL-15-triggered mTORC1 activation.
Nature communications
Yang M,Chen S,Du J,He J,Wang Y,Li Z,Liu G,Peng W,Zeng X,Li D,Xu P,Guo W,Chang Z,Wang S,Tian Z,Dong Z
Published figure using NK1.1 monoclonal antibody (Product # 17-5941-82) in Flow Cytometry
Wed Sep 07 00:00:00 EDT 2016
Enrichment of IFN-γ producing cells in different murine adipose tissue depots upon infection with an apicomplexan parasite.
Scientific reports
Teixeira L,Marques RM,Ferreirinha P,Bezerra F,Melo J,Moreira J,Pinto A,Correia A,Ferreira PG,Vilanova M
17-5941 was used in Flow cytometry/Cell sorting to investigate the contribution of NK and T cells to the production of IFN-γ in the adipose tissue of Neospora caninum infected mice.
Tue Mar 22 00:00:00 EDT 2016
Natural killer cells require monocytic Gr-1(+)/CD11b(+) myeloid cells to eradicate orthotopically engrafted glioma cells.
Oncoimmunology
Baker GJ,Chockley P,Zamler D,Castro MG,Lowenstein PR
17-5941 was used in Flow cytometry/Cell sorting to examine the mechanisms used by malignant gliomas to suppress anti-tumour natural killer cell activity.
Wed Jun 01 00:00:00 EDT 2016
T Lymphocyte-Specific Activation of Nrf2 Protects from AKI.
Journal of the American Society of Nephrology : JASN
Noel S,Martina MN,Bandapalle S,Racusen LC,Potteti HR,Hamad AR,Reddy SP,Rabb H
17-5941 was used in Flow cytometry/Cell sorting to study how T lymphocyte-specific activation of Nrf2 protects from IR-induced AKI, and investigate the novel mechanism of tissue protection behind this.
Tue Dec 01 00:00:00 EST 2015
Atypical chemokine receptor 1 deficiency reduces atherogenesis in ApoE-knockout mice.
Cardiovascular research
Wan W,Liu Q,Lionakis MS,Marino AP,Anderson SA,Swamydas M,Murphy PM
17-5941 was used in Flow cytometry/Cell sorting to investigate the role of Ackr1 in chronic inflammation, in particular in atherogenesis, using the apolipoprotein E-deficient mouse model.
Mon Jun 01 00:00:00 EDT 2015
Caribbean and La Réunion Chikungunya Virus Isolates Differ in Their Capacity To Induce Proinflammatory Th1 and NK Cell Responses and Acute Joint Pathology.
Journal of virology
Teo TH,Her Z,Tan JJ,Lum FM,Lee WW,Chan YH,Ong RY,Kam YW,Leparc-Goffart I,Gallian P,Rénia L,de Lamballerie X,Ng LF
17-5941 was used in Flow cytometry/Cell sorting to demonstrate that the Caribbean CHIKV isolate has an enfeebled replication and induces a less pathogenic response in the mammalian host.
Sat Aug 01 00:00:00 EDT 2015
Monitoring and cell-specific deletion of C5aR1 using a novel floxed GFP-C5aR1 reporter knock-in mouse.
Journal of immunology (Baltimore, Md. : 1950)
Karsten CM,Laumonnier Y,Eurich B,Ender F,Bröker K,Roy S,Czabanska A,Vollbrandt T,Figge J,Köhl J
17-5941 was used in Flow cytometry/Cell sorting to study cell-specific deletion of C5aR1 using a GFP-reporter knock-in mouse model.
Sun Feb 15 00:00:00 EST 2015
Favorable alteration of tumor microenvironment by immunomodulatory cytokines for efficient T-cell therapy in solid tumors.
PloS one
Tähtinen S,Kaikkonen S,Merisalo-Soikkeli M,Grönberg-Vähä-Koskela S,Kanerva A,Parviainen S,Vähä-Koskela M,Hemminki A
Published figure using NK1.1 monoclonal antibody (Product # 17-5941-82) in Flow Cytometry
Thu Apr 28 00:00:00 EDT 2016
Metronomic cyclophosphamide eradicates large implanted GL261 gliomas by activating antitumor Cd8+ T-cell responses and immune memory.
Oncoimmunology
Wu J,Waxman DJ
Published figure using NK1.1 monoclonal antibody (Product # 17-5941-82) in Flow Cytometry
Wed Apr 01 00:00:00 EDT 2015
Natural killer cell NKG2D and granzyme B are critical for allergic pulmonary inflammation.
The Journal of allergy and clinical immunology
Farhadi N,Lambert L,Triulzi C,Openshaw PJ,Guerra N,Culley FJ
17-5941 was used in Flow cytometry/Cell sorting to investigate the importance of natural killer cells in house dust mite-triggered allergic response.
Sat Mar 01 00:00:00 EST 2014
Natural killer cells eradicate galectin-1-deficient glioma in the absence of adaptive immunity.
Cancer research
Baker GJ,Chockley P,Yadav VN,Doherty R,Ritt M,Sivaramakrishnan S,Castro MG,Lowenstein PR
Published figure using NK1.1 monoclonal antibody (Product # 17-5941-82) in Flow Cytometry
Mon Sep 15 00:00:00 EDT 2014
Natural killer cells eradicate galectin-1-deficient glioma in the absence of adaptive immunity.
Cancer research
Baker GJ,Chockley P,Yadav VN,Doherty R,Ritt M,Sivaramakrishnan S,Castro MG,Lowenstein PR
Published figure using NK1.1 monoclonal antibody (Product # 17-5941-82) in Flow Cytometry
Mon Sep 15 00:00:00 EDT 2014
CD41 is a reliable identification and activation marker for murine basophils in the steady state and during helminth and malarial infections.
European journal of immunology
Bakocevic N,Claser C,Yoshikawa S,Jones LA,Chew S,Goh CC,Malleret B,Larbi A,Ginhoux F,de Lafaille MC,Karasuyama H,Renia L,Ng LG
17-5941 was used in Flow cytometry/Cell sorting to study the CD41 expression within basophils from the blood during both steady state and malarial inections within mice.
Sun Jun 01 00:00:00 EDT 2014
E and Id proteins influence invariant NKT cell sublineage differentiation and proliferation.
Journal of immunology (Baltimore, Md. : 1950)
D'Cruz LM,Stradner MH,Yang CY,Goldrath AW
17-5941 was used in Flow cytometry/Cell sorting to investigate the mechanism by which E and Id proteins control the development of invariant NKT sublineages after positive selection.
Sat Mar 01 00:00:00 EST 2014
Intrahepatic innate lymphoid cells secrete IL-17A and IL-17F that are crucial for T cell priming in viral infection.
Journal of immunology (Baltimore, Md. : 1950)
Jie Z,Liang Y,Hou L,Dong C,Iwakura Y,Soong L,Cong Y,Sun J
17-5941 was used in Flow cytometry/Cell sorting to investigate the source and regulation of the IL-17 surge in the liver microenvironment that occurs early in the response to viral infection.
Tue Apr 01 00:00:00 EDT 2014
Leukocyte population dynamics and detection of IL-9 as a major cytokine at the mouse fetal-maternal interface.
PloS one
Habbeddine M,Verbeke P,Karaz S,Bobé P,Kanellopoulos-Langevin C
Published figure using NK1.1 monoclonal antibody (Product # 17-5941-82) in Flow Cytometry
Wed Jun 10 00:00:00 EDT 2015
Toll-like receptor agonist augments virus-like particle-mediated protection from Ebola virus with transient immune activation.
PloS one
Martins KA,Steffens JT,van Tongeren SA,Wells JB,Bergeron AA,Dickson SP,Dye JM,Salazar AM,Bavari S
17-5941 was used in Flow cytometry/Cell sorting to explore the impact of a stabilised dsRNA mimic, polyICLC, on Ebola virus-like particle vaccination of C57BL/6 mice and Hartley guinea pigs.
Tue Jan 20 00:00:00 EST 2015
Type 2 innate lymphoid cells control eosinophil homeostasis.
Nature
Nussbaum JC,Van Dyken SJ,von Moltke J,Cheng LE,Mohapatra A,Molofsky AB,Thornton EE,Krummel MF,Chawla A,Liang HE,Locksley RM
17-5941 was used in Flow cytometry/Cell sorting to investigate the processes underlying regulation of cytokine and chemokines for eosinophil development and survival, showing that type 2 innate lymphoid cells control eosinophil homeostasis.
Thu Oct 10 00:00:00 EDT 2013
CX3CR1-dependent renal macrophage survival promotes Candida control and host survival.
The Journal of clinical investigation
Lionakis MS,Swamydas M,Fischer BG,Plantinga TS,Johnson MD,Jaeger M,Green NM,Masedunskas A,Weigert R,Mikelis C,Wan W,Lee CC,Lim JK,Rivollier A,Yang JC,Laird GM,Wheeler RT,Alexander BD,Perfect JR,Gao JL,Kullberg BJ,Netea MG,Murphy PM
17-5941 was used in Flow cytometry/Cell sorting to elucidate the roles of innate immune cells in the pathogenesis of C. albicans.
Sun Dec 01 00:00:00 EST 2013
Lipidoid Nanoparticles Containing PD-L1 siRNA Delivered In Vivo Enter Kupffer Cells and Enhance NK and CD8(+) T Cell-mediated Hepatic Antiviral Immunity.
Molecular therapy. Nucleic acids
Dolina JS,Sung SS,Novobrantseva TI,Nguyen TM,Hahn YS
17-5941 was used in Flow cytometry/Cell sorting to demonstrate that PD-L1 knockdown on KCs is central in determining the outcome of liver viral infections, and they represent a new class of gene therapy.
Tue Feb 19 00:00:00 EST 2013
CD40 deficiency in mice exacerbates obesity-induced adipose tissue inflammation, hepatic steatosis, and insulin resistance.
American journal of physiology. Endocrinology and metabolism
Guo CA,Kogan S,Amano SU,Wang M,Dagdeviren S,Friedline RH,Aouadi M,Kim JK,Czech MP
17-5941 was used in Flow cytometry/Cell sorting to uncover the anti-inflammatory role of CD40 in a unique CD40-null mouse model of hepatic steatosis.
Wed May 01 00:00:00 EDT 2013
Differential expression of the Ly49G(B6), but not the Ly49G(BALB), receptor isoform during natural killer cell reconstitution after hematopoietic stem cell transplantation.
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation
Barao I,Wright PW,Sungur CM,Anderson SK,Redelman D,Murphy WJ
17-5941 was used in Flow cytometry/Cell sorting to evaluate the expression of two isoforms of the inhibitory NK cell receptor, Ly49G, in CB6F1 mice following hematopoietic stem cell transplantation.
Tue Oct 01 00:00:00 EDT 2013
Role of NK cell subsets in organ-specific murine melanoma metastasis.
PloS one
Ballas ZK,Buchta CM,Rosean TR,Heusel JW,Shey MR
17-5941 was used in Flow cytometry/Cell sorting to examine the organ-specific functions of natural killer cells.
Thu Jan 16 00:00:00 EST 2014
ZBTB1 is a determinant of lymphoid development.
The Journal of experimental medicine
Siggs OM,Li X,Xia Y,Beutler B
17-5941 was used in Flow cytometry/Cell sorting to identify a mutation causative of complete and cell-intrinsic T cell deficiency.
Mon Jan 16 00:00:00 EST 2012
Nuclear export of histone deacetylase 7 during thymic selection is required for immune self-tolerance.
The EMBO journal
Kasler HG,Lim HW,Mottet D,Collins AM,Lee IS,Verdin E
17-5941 was used in Flow cytometry/Cell sorting to examine the effect of blocking TCR-dependent nuclear export of HDAC7 during thymic selection, showing that HDAC7 is required for immune self-tolerance.
Wed Nov 28 00:00:00 EST 2012
VEGF receptor inhibitors block the ability of metronomically dosed cyclophosphamide to activate innate immunity-induced tumor regression.
Cancer research
Doloff JC,Waxman DJ
Published figure using NK1.1 monoclonal antibody (Product # 17-5941-82) in Flow Cytometry
Thu Mar 01 00:00:00 EST 2012
Type II NKT cells facilitate Alum-sensing and humoral immunity.
Journal of leukocyte biology
Shah HB,Devera TS,Rampuria P,Lang GA,Lang ML
17-5941 was used in Flow cytometry/Cell sorting to show that type II NKT cells function as part of the Alum-sensing apparatus and in a CD1d-dependent manner, facilitate T(H)2-driven humoral immunity.
Mon Oct 01 00:00:00 EDT 2012
Differential requirements for IRF-2 in generation of CD1d-independent T cells bearing NK cell receptors.
Journal of immunology (Baltimore, Md. : 1950)
Notake T,Horisawa S,Sanjo H,Miyagawa S,Hida S,Taki S
17-5941 was used in Flow cytometry/Cell sorting to investigate the mechanisms behind the generation and function of NKR(+) T cells.
Tue May 15 00:00:00 EDT 2012
STAT1-independent control of a neurotropic measles virus challenge in primary neurons and infected mice.
Journal of immunology (Baltimore, Md. : 1950)
O'Donnell LA,Conway S,Rose RW,Nicolas E,Slifker M,Balachandran S,Rall GF
17-5941 was used in Flow cytometry/Cell sorting to determine whether STAT1 is required for IFN-γ-mediated protection from infection in neurons, showing that absence of STAT1 in mice did not restrict the ability of IFN-γ to control viral infection, through a pathway independent of the usual pathway.
Wed Feb 15 00:00:00 EST 2012
Mouse Ly49G2+ NK cells dominate early responses during both immune reconstitution and activation independently of MHC.
Blood
Barao I,Alvarez M,Ames E,Orr MT,Stefanski HE,Blazar BR,Lanier LL,Anderson SK,Redelman D,Murphy WJ
17-5941 was used in Flow cytometry/Cell sorting to show that during reconstitution after HSCT and various activation stimuli, preferential expansion of the Ly49G2 receptor on NK cells occurs independently of MHC haplotype.
Thu Jun 30 00:00:00 EDT 2011
Myeloid-derived suppressor cells are implicated in regulating permissiveness for tumor metastasis during mouse gestation.
The Journal of clinical investigation
Mauti LA,Le Bitoux MA,Baumer K,Stehle JC,Golshayan D,Provero P,Stamenkovic I
17-5941 was used in Flow cytometry/Cell sorting to suggest that the functions of MDSCs may represent a shared mechanism of immunosuppression that occurs during gestation and tumour growth.
Fri Jul 01 00:00:00 EDT 2011
Retroviral insertional mutagenesis can contribute to immortalization of mature T lymphocytes.
Molecular medicine (Cambridge, Mass.)
Newrzela S,Cornils K,Heinrich T,Schläger J,Yi JH,Lysenko O,Kimpel J,Fehse B,von Laer D
17-5941 was used in Flow cytometry/Cell sorting to investigate possible inducers of the malignant transformation of mature T lymphocytes.
Fri Aug 03 00:00:00 EDT 2012
Hydrodynamic delivery of human IL-15 cDNA increases murine natural killer cell recovery after syngeneic bone marrow transplantation.
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation
Barao I,Alvarez M,Redelman D,Weiss JM,Ortaldo JR,Wiltrout RH,Murphy WJ
17-5941 was used in Flow cytometry/Cell sorting to highlight cytokine gene transfer-based methods as a potential platform for natural killer cell recovery after bone marrow transplantation in mice.
Thu Dec 01 00:00:00 EST 2011
Histone deacetylase 7 regulates cell survival and TCR signaling in CD4/CD8 double-positive thymocytes.
Journal of immunology (Baltimore, Md. : 1950)
Kasler HG,Young BD,Mottet D,Lim HW,Collins AM,Olson EN,Verdin E
17-5941 was used in Flow cytometry/Cell sorting to study the regulation of cell survival and TCR signaling in CD4/CD8 double-positive thymocytes by histone deacetylase 7.
Fri Apr 15 00:00:00 EDT 2011
DX5+NKT cells display phenotypical and functional differences between spleen and liver as well as NK1.1-Balb/c and NK1.1+ C57Bl/6 mice.
BMC immunology
Werner JM,Busl E,Farkas SA,Schlitt HJ,Geissler EK,Hornung M
17-5941 was used in Flow cytometry/Cell sorting to investigate the expression of several T cell and NK cell markers in spleen and liver DX5+NKT cell subsets in mice.
Fri Apr 29 00:00:00 EDT 2011
Visualization of immune response kinetics in full allogeneic chimeras.
American journal of blood research
Elkin G,Prigozhina TB,Slavin S,Gurevitch O,Khitrin S,Resnick IB
17-5941 was used in Flow cytometry/Cell sorting to visualise the changes in full chimera immune response kinetics after co-transplantation of donor and host hematopoietic cells together.
Thu Aug 23 00:00:00 EDT 2012
Basophils orchestrate chronic allergic dermatitis and protective immunity against helminths.
Immunity
Ohnmacht C,Schwartz C,Panzer M,Schiedewitz I,Naumann R,Voehringer D
17-5941 was used in Flow cytometry/Cell sorting to demonstrate that basophils play an important role for protective immunity against helminths and orchestrate chronic allergic inflammation.
Fri Sep 24 00:00:00 EDT 2010
Alternatively activated macrophages inhibit T-cell proliferation by Stat6-dependent expression of PD-L2.
Blood
Huber S,Hoffmann R,Muskens F,Voehringer D
17-5941 was used in Flow cytometry/Cell sorting to study how IL-4 induced the expression of PD-L2 on CAM, and LPS increased the expression of PD-L1 on alternatively activated macrophages.
Thu Oct 28 00:00:00 EDT 2010
Chimeric NKG2D T cells require both T cell- and host-derived cytokine secretion and perforin expression to increase tumor antigen presentation and systemic immunity.
Journal of immunology (Baltimore, Md. : 1950)
Barber A,Sentman CL
17-5941 was used in Flow cytometry/Cell sorting to determine the mechanisms that chNKG2D T cells require to induce host immunity against ovarian tumours and which of the host immune cells are involved in tumour elimination.
Sat Aug 15 00:00:00 EDT 2009
Gammadelta T lymphocyte homeostasis is negatively regulated by beta2-microglobulin.
Journal of immunology (Baltimore, Md. : 1950)
French JD,Roark CL,Born WK,O'Brien RL
17-5941 was used in Flow cytometry/Cell sorting to investigate the role of β2-microglobulin in regulating gamma-delta T lymphocyte homeostasis.
Sun Feb 15 00:00:00 EST 2009
NKG2A inhibits invariant NKT cell activation in hepatic injury.
Journal of immunology (Baltimore, Md. : 1950)
Kawamura T,Takeda K,Kaneda H,Matsumoto H,Hayakawa Y,Raulet DH,Ikarashi Y,Kronenberg M,Yagita H,Kinoshita K,Abo T,Okumura K,Smyth MJ
17-5941 was used in Flow cytometry/Cell sorting to investigate the role of NK cell receptors in iNKT cell activation, showing that NKG2A-mediated signalling negatively regulated iNKT activation and hepatic injury.
Thu Jan 01 00:00:00 EST 2009
Psychological stress exacerbates primary vaginal herpes simplex virus type 1 (HSV-1) infection by impairing both innate and adaptive immune responses.
Brain, behavior, and immunity
Ashcraft KA,Bonneau RH
17-5941 was used in Flow cytometry/Cell sorting to investigate the role that psychological stress, through its suppression of both innate and adaptive immune responses, plays in the ability of the body to control vaginal Herpes Simplex Virus type 1 infection.
Sat Nov 01 00:00:00 EDT 2008
Runx proteins are involved in regulation of CD122, Ly49 family and IFN-gamma expression during NK cell differentiation.
International immunology
Ohno S,Sato T,Kohu K,Takeda K,Okumura K,Satake M,Habu S
17-5941 was used in Magnetic cell separation to investigate the role of Runx family proteins in NK cells, showing that they are involved in regulation of CD122, Ly49 family and IFN-gamma expression during differentiation.
Tue Jan 01 00:00:00 EST 2008
Phenotypic switching in Cryptococcus neoformans contributes to virulence by changing the immunological host response.
Infection and immunity
Guerrero A,Fries BC
17-5941 was used in Flow cytometry/Cell sorting to compare survival rates and characterise the host responses of C. neoformans-resistant mice.
Mon Sep 01 00:00:00 EDT 2008
Tumor growth impedes natural-killer-cell maturation in the bone marrow.
Blood
Richards JO,Chang X,Blaser BW,Caligiuri MA,Zheng P,Liu Y
17-5941 was used in Flow cytometry/Cell sorting to demonstrate that tumour growth can impede functional maturation of NK cells, most likely by interrupting the requisite IL-15 signalling pathway.
Sat Jul 01 00:00:00 EDT 2006
In vivo survival and homeostatic proliferation of natural killer cells.
The Journal of experimental medicine
Prlic M,Blazar BR,Farrar MA,Jameson SC
17-5941 was used in Flow cytometry/Cell sorting to show that mouse NK cells undergo homeostatic proliferation when transferred into NK-deficient Rag-/- gammaC-/- hosts.
Mon Apr 21 00:00:00 EDT 2003
