Invitrogen

MALT1 Polyclonal Antibody

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MALT1 Antibody (PA1-41183) in WB

Western blot analysis of MALT1 in Jurkat cell lysate. Samples were incubated in MALT1 polyclonal antibody (Product # PA1-41183) using a dilution of 0.5 µg/mL.

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Product Details

PA1-41183

Applications

Tested Dilution

Publications

Western Blot (WB)

0.5-2 µg/mL

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Synthetic peptide corresponding to residues 43-57 E(43) L L D Q A P E G R G W R R L(57) of human MALT1.

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.5 mg/mL

Purification

Protein G

Storage buffer

PBS with 0.2% gelatin

Contains

0.05% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2139128

Target Information

MALT1/Paracaspase (MALT1) was independently identified as a member of the human paracaspase family and an interacting partner of B-cell lymphoma (Uren et al., 2000). MALT1 is a caspase-like protein that contains an N-terminal death domain, two Ig-like domains, and a C-terminal caspase-like domain. It binds to Bcl10 through its Ig-like domains and cooperates with Bcl10 to activate NF-kappaB.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: caspase-like protein; DKFZp434L132; MALT lymphoma-associated translocation; malt-1; MALT1 protease; mucosa associated lymphoid tissue lymphoma translocation gene 1; Mucosa-associated lymphoid tissue lymphoma translocation protein 1; Paracaspase; paracaspase 1; paracaspase-1

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Gene Aliases: IMD12; MALT1; MLT; MLT1; PCASP1

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UniProt ID: (Human) Q9UDY8

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Entrez Gene ID: (Human) 10892

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Function(s)

protease binding cysteine-type endopeptidase activity ubiquitin-protein transferase activity signal transducer activity protein binding peptidase activity kinase activator activity protein self-association cysteine protease

Process(es)

B-1 B cell differentiation stimulatory C-type lectin receptor signaling pathway response to molecule of bacterial origin positive regulation of T cell cytokine production proteolysis defense response activation of NF-kappaB-inducing kinase activity response to fungus protein ubiquitination positive regulation of protein ubiquitination positive regulation of interleukin-2 production Fc-epsilon receptor signaling pathway T cell proliferation regulation of apoptotic process negative regulation of apoptotic process positive regulation of I-kappaB kinase/NF-kappaB signaling innate immune response T cell receptor signaling pathway regulation of T cell receptor signaling pathway positive regulation of T cell activation positive regulation of NF-kappaB transcription factor activity nuclear export protein oligomerization

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If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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MALT1 Polyclonal Antibody

MALT1 Antibody (PA1-41183) in WB

Product Details

PA1-41183

Western Blot (WB)

Species Reactivity

Host/Isotype

Class

Type

Immunogen

Conjugate

Form

Concentration

Purification

Storage buffer

Contains

Storage conditions

Shipping conditions

RRID

Target Information

References (0)

Bioinformatics

Performance Guarantee

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