Product References
CREB3L2-ATF4 heterodimerization defines a transcriptional hub of Alzheimer's disease gene expression linked to neuropathology.
Science advances
Gouveia Roque C,Chung KM,McCurdy EP,Jagannathan R,Randolph LK,Herline-Killian K,Baleriola J,Hengst U
MA1-118 was used in Western Blotting to reveal differential transcription factor dimerization as a mechanism linking disease stimuli to the development of pathogenic cellular states.
Fri Mar 03 00:00:00 EST 2023
Generation of an MTM1-mutant iPSC line (CRICKi008-A) from an individual with X-linked myotubular myopathy (XLMTM).
Stem cell research
Devito LG,Lionello VM,Muntoni F,Tedesco FS,Healy L
MA1-118 was used in Immunocytochemistry-immunofluorescence to show that this new MTM1-mutant iPSC line could facilitate disease-modelling and therapy development studies for XLMTM.
Thu Jun 01 00:00:00 EDT 2023
Mechanisms and treatments of neuropathic itch in a mouse model of lymphoma.
The Journal of clinical investigation
Chen O,He Q,Han Q,Furutani K,Gu Y,Olexa M,Ji RR
MA1-118 was used in Immunohistochemistry to suggest distinct mechanisms underlying acute, chronic, and neuropathic itch.
Wed Feb 15 00:00:00 EST 2023
A Gelatin Methacrylate-Based Hydrogel as a Potential Bioink for 3D Bioprinting and Neuronal Differentiation.
Pharmaceutics
Cruz EM,Machado LS,Zamproni LN,Bim LV,Ferreira PS,Pinto LA,Pessan LA,Backes EH,Porcionatto MA
MA1-118 was used in Immunocytochemistry-immunofluorescence to indicate that bioinks, 2.5/2.5G/GMA_Gx and 4GMA_Gx, can support neural cell survival and modulate neural differentiation.
Mon Feb 13 00:00:00 EST 2023
Silencing miR-21-5p in sensory neurons reverses neuropathic allodynia via activation of TGF-β-related pathway in macrophages.
The Journal of clinical investigation
Zeboudj L,Sideris-Lampretsas G,Silva R,Al-Mudaris S,Picco F,Fox S,Chambers D,Malcangio M
MA1-118 was used in Immunohistochemistry-immunofluorescence to show that miR-21 conditional deletion in DRG neurons was coupled with lack of upregulation of chemokine CCL2 after nerve injury and reduced accumulation of CCR2-expressing macrophages, which showed TGF-β-related pathway activation and acquired an M2-like antinociceptive phenotype.
Thu Jun 01 00:00:00 EDT 2023
Deposition chamber technology as building blocks for a standardized brain-on-chip framework.
Microsystems & nanoengineering
Maisonneuve BGC,Libralesso L,Miny L,Batut A,Rontard J,Gleyzes M,Boudra B,Viera J,Debis D,Larramendy F,Jost V,Honegger T
Published figure using beta-3 Tubulin monoclonal antibody (Product # MA1-118) in Immunocytochemistry
Fri Aug 05 00:00:00 EDT 2022
Modulation of Amyloid β-Induced Microglia Activation and Neuronal Cell Death by Curcumin and Analogues.
International journal of molecular sciences
De Lorenzi E,Franceschini D,Contardi C,Di Martino RMC,Seghetti F,Serra M,Bisceglia F,Pagetta A,Zusso M,Belluti F
Published figure using beta-3 Tubulin monoclonal antibody (Product # MA1-118) in Immunocytochemistry
Fri Apr 15 00:00:00 EDT 2022
Lotus essential oil improves neurite elongation and facilitates functional recovery after peripheral nerve injury.
Biomedical reports
Sriraksa N,Kongsui R,Thongrong S
MA1-118 was used in Immunocytochemistry-immunofluorescence to suggest that LEO may serve as a novel pharmacological option for the management of peripheral nerve injury.
Fri Apr 01 00:00:00 EDT 2022
Pathological mitophagy disrupts mitochondrial homeostasis in Leber's hereditary optic neuropathy.
Cell reports
Danese A,Patergnani S,Maresca A,Peron C,Raimondi A,Caporali L,Marchi S,La Morgia C,Del Dotto V,Zanna C,Iannielli A,Segnali A,Di Meo I,Cavaliere A,Lebiedzinska-Arciszewska M,Wieckowski MR,Martinuzzi A,Moraes-Filho MN,Salomao SR,Berezovsky A,Belfort R,Buser C,Ross-Cisneros FN,Sadun AA,Tacchetti C,Broccoli V,Giorgi C,Tiranti V,Carelli V,Pinton P
MA1-118 was used in Immunocytochemistry-immunofluorescence to show that a sustained pathological autophagy and compartment-specific mitophagy activity affects Leber's hereditary optic neuropathy patient-derived cells and cybrids, as well as induced pluripotent-stem-cell-derived neurons.
Tue Jul 19 00:00:00 EDT 2022
Impact of Siponimod on Enteric and Central Nervous System Pathology in Late-Stage Experimental Autoimmune Encephalomyelitis.
International journal of molecular sciences
Weier A,Enders M,Kirchner P,Ekici A,Bigaud M,Kapitza C,Wörl J,Kuerten S
MA1-118 was used in Immunocytochemistry-immunofluorescence to investigate the effects of siponimod on the enteric nervous system (ENS) and central nervous system (CNS) in the experimental autoimmune encephalomyelitis model of multiple sclerosis.
Thu Nov 17 00:00:00 EST 2022
COVID-19-related anosmia is associated with viral persistence and inflammation in human olfactory epithelium and brain infection in hamsters.
Science translational medicine
de Melo GD,Lazarini F,Levallois S,Hautefort C,Michel V,Larrous F,Verillaud B,Aparicio C,Wagner S,Gheusi G,Kergoat L,Kornobis E,Donati F,Cokelaer T,Hervochon R,Madec Y,Roze E,Salmon D,Bourhy H,Lecuit M,Lledo PM
MA1-118 was used in Immunocytochemistry, Immunohistochemistry, Immunohistochemistry (Paraffin) to understand the connection between SARS-CoV-2 infection and possible olfactory dysfunction.
Wed Jun 02 00:00:00 EDT 2021
COVID-19-related anosmia is associated with viral persistence and inflammation in human olfactory epithelium and brain infection in hamsters.
Science translational medicine
de Melo GD,Lazarini F,Levallois S,Hautefort C,Michel V,Larrous F,Verillaud B,Aparicio C,Wagner S,Gheusi G,Kergoat L,Kornobis E,Donati F,Cokelaer T,Hervochon R,Madec Y,Roze E,Salmon D,Bourhy H,Lecuit M,Lledo PM
MA1-118 was used in Immunocytochemistry, Immunohistochemistry, Immunohistochemistry (Paraffin) to understand the connection between SARS-CoV-2 infection and possible olfactory dysfunction.
Wed Jun 02 00:00:00 EDT 2021
COVID-19-related anosmia is associated with viral persistence and inflammation in human olfactory epithelium and brain infection in hamsters.
Science translational medicine
de Melo GD,Lazarini F,Levallois S,Hautefort C,Michel V,Larrous F,Verillaud B,Aparicio C,Wagner S,Gheusi G,Kergoat L,Kornobis E,Donati F,Cokelaer T,Hervochon R,Madec Y,Roze E,Salmon D,Bourhy H,Lecuit M,Lledo PM
MA1-118 was used in Immunocytochemistry, Immunohistochemistry, Immunohistochemistry (Paraffin) to understand the connection between SARS-CoV-2 infection and possible olfactory dysfunction.
Wed Jun 02 00:00:00 EDT 2021
Neuron and astrocyte aggregation and sorting in three-dimensional neuronal constructs.
Communications biology
Hasan MF,Berdichevsky Y
MA1-118 was used in Immunocytochemistry-immunoflourescence to develop linear, adhered rat and human 3D neuronal-astrocyte cultures to study aggregation and sorting of these cells.
Mon May 17 00:00:00 EDT 2021
Neuron and astrocyte aggregation and sorting in three-dimensional neuronal constructs.
Communications biology
Hasan MF,Berdichevsky Y
MA1-118 was used in Immunocytochemistry-immunoflourescence to develop linear, adhered rat and human 3D neuronal-astrocyte cultures to study aggregation and sorting of these cells.
Mon May 17 00:00:00 EDT 2021
Inhibition of TGF-β repairs spinal cord injury by attenuating EphrinB2 expressing through inducing miR-484 from fibroblast.
Cell death discovery
Pan D,Yang F,Zhu S,Li Y,Ning G,Feng S
MA1-118 was used in Immunohistochemistry to find systemic injection of TGF-β neutralizing antibody induces the protection of axon growth, survival of neurons, and functional recovery, whereas erythropoietin-producing hepatoma interactor B2 (EphrinB2) expression and fibroblasts distribution are attenuated.
Thu Oct 28 00:00:00 EDT 2021
Astrocytes Exhibit a Protective Role in Neuronal Firing Patterns under Chemically Induced Seizures in Neuron-Astrocyte Co-Cultures.
International journal of molecular sciences
Ahtiainen A,Genocchi B,Tanskanen JMA,Barros MT,Hyttinen JAK,Lenk K
MA1-118 was used in Immunocytochemistry-immunofluorescence to assess the modulatory roles of astrocytes during epileptic-like conditions and in compensating drug-elicited hyperactivity.
Thu Nov 25 00:00:00 EST 2021
Zika Virus Targets Glioblastoma Stem Cells through a SOX2-Integrin αvβ5 Axis.
Cell stem cell
Zhu Z,Mesci P,Bernatchez JA,Gimple RC,Wang X,Schafer ST,Wettersten HI,Beck S,Clark AE,Wu Q,Prager BC,Kim LJY,Dhanwani R,Sharma S,Garancher A,Weis SM,Mack SC,Negraes PD,Trujillo CA,Penalva LO,Feng J,Lan Z,Zhang R,Wessel AW,Dhawan S,Diamond MS,Chen CC,Wechsler-Reya RJ,Gage FH,Hu H,Siqueira-Neto JL,Muotri AR,Cheresh DA,Rich JN
MA1-118 was used in Immunohistochemistry-immunofluorescence to demonstrate that ZIKV preferentially infected and killed GSCs and stem-like cells in medulloblastoma and ependymoma in a SOX2-dependent manner.
Thu Feb 06 00:00:00 EST 2020
P-Glycoprotein Inhibition Exacerbates Paclitaxel Neurotoxicity in Neurons and Patients With Cancer.
Clinical pharmacology and therapeutics
Stage TB,Mortensen C,Khalaf S,Steffensen V,Hammer HS,Xiong C,Nielsen F,Poetz O,Svenningsen ÅF,Rodriguez-Antona C,Kroetz DL
Published figure using beta-3 Tubulin monoclonal antibody (Product # MA1-118) in Immunocytochemistry
Tue Sep 01 00:00:00 EDT 2020
P-Glycoprotein Inhibition Exacerbates Paclitaxel Neurotoxicity in Neurons and Patients With Cancer.
Clinical pharmacology and therapeutics
Stage TB,Mortensen C,Khalaf S,Steffensen V,Hammer HS,Xiong C,Nielsen F,Poetz O,Svenningsen ÅF,Rodriguez-Antona C,Kroetz DL
Published figure using beta-3 Tubulin monoclonal antibody (Product # MA1-118) in Immunocytochemistry
Tue Sep 01 00:00:00 EDT 2020
Modeling medulloblastoma in vivo and with human cerebellar organoids.
Nature communications
Ballabio C,Anderle M,Gianesello M,Lago C,Miele E,Cardano M,Aiello G,Piazza S,Caron D,Gianno F,Ciolfi A,Pedace L,Mastronuzzi A,Tartaglia M,Locatelli F,Ferretti E,Giangaspero F,Tiberi L
Published figure using beta-3 Tubulin monoclonal antibody (Product # MA1-118) in Immunofluorescence
Wed Jan 29 00:00:00 EST 2020
TFAP2C facilitates somatic cell reprogramming by inhibiting c-Myc-dependent apoptosis and promoting mesenchymal-to-epithelial transition.
Cell death & disease
Wang Y,Chen S,Jiang Q,Deng J,Cheng F,Lin Y,Cheng L,Ye Y,Chen X,Yao Y,Zhang X,Shi G,Dai L,Su X,Peng Y,Deng H
MA1-118 was used in Immunocytochemistry to demonstrate Tfap2c is induced during the generation of iPSCs from mouse fibroblasts and acts as a facilitator for iPSCs formation.
Thu Jun 25 00:00:00 EDT 2020
Enhancement of BDNF Expression and Memory by HDAC Inhibition Requires BET Bromodomain Reader Proteins.
The Journal of neuroscience : the official journal of the Society for Neuroscience
Sartor GC,Malvezzi AM,Kumar A,Andrade NS,Wiedner HJ,Vilca SJ,Janczura KJ,Bagheri A,Al-Ali H,Powell SK,Brown PT,Volmar CH,Foster TC,Zeier Z,Wahlestedt C
MA1-118X was used in Immunocytochemistry-immunoflourescence to reveal that BRD4 is necessary for enhancing brain-derived neurotrophic factor (BDNF) expression and improved memory following histone deacetylase inhibition.
Wed Jan 23 00:00:00 EST 2019
Induced Pluripotent Stem Cell Derivation and Ex Vivo Gene Correction Using a Mucopolysaccharidosis Type 1 Disease Mouse Model.
Stem cells international
Miki T,Vazquez L,Yanuaria L,Lopez O,Garcia IM,Ohashi K,Rodriguez NS
MA1-118 was used in Immunocytochemistry-immunoflourescence to support the concept of ex vivo gene editing therapy using iPSC and CRISPR/Cas9 technologies for MPS-1 patients.
Wed Sep 30 00:00:00 EDT 2020
Investigating Nrg1 Signaling in the Regenerating Axolotl Spinal Cord Using Multiplexed FISH.
Developmental neurobiology
Freitas PD,Lovely AM,Monaghan JR
MA1-118 was used in Immunohistochemistry to investigate if neuregulin 1 (Nrg1)/ErbB2 signaling is an important pathway in the regulation of neural stem cell proliferation in the spinal cord of the axolotl salamander (Ambystoma mexicanum).
Wed May 01 00:00:00 EDT 2019
Investigating Nrg1 Signaling in the Regenerating Axolotl Spinal Cord Using Multiplexed FISH.
Developmental neurobiology
Freitas PD,Lovely AM,Monaghan JR
MA1-118 was used in Immunohistochemistry to investigate if neuregulin 1 (Nrg1)/ErbB2 signaling is an important pathway in the regulation of neural stem cell proliferation in the spinal cord of the axolotl salamander (Ambystoma mexicanum).
Wed May 01 00:00:00 EDT 2019
Altered Gut Microbiome in Parkinson's Disease and the Influence of Lipopolysaccharide in a Human α-Synuclein Over-Expressing Mouse Model.
Frontiers in neuroscience
Gorecki AM,Preskey L,Bakeberg MC,Kenna JE,Gildenhuys C,MacDougall G,Dunlop SA,Mastaglia FL,Akkari PA,Koengten F,Anderton RS
MA1-118 was used in Western Blotting to show lipopolysaccharides administration in mice causes earlier motor troubles and also an altered gut microbiome is present in patients with Parkinson's disease.
Tue Sep 29 00:00:00 EDT 2020
Growth Cone Tctp Is Dynamically Regulated by Guidance Cues.
Frontiers in molecular neuroscience
Gouveia Roque C,Holt CE
MA1-118 was used in Western Blotting to study the dynamic regulation of growth cone translationally controlled tumour protein by Netrin-1 and Ephrin-A1.
Sat Jan 29 00:00:00 EST 2022
Mesenchymal Stem Cells (MSCs) Coculture Protects [Ca2+]i Orchestrated Oxidant Mediated Damage in Differentiated Neurons In Vitro.
Cells
Alhazzani A,Rajagopalan P,Albarqi Z,Devaraj A,Mohamed MH,Al-Hakami A,Chandramoorthy HC
MA1-118 was used in Immunocytochemistry-immunoflourescence to study the sequence of events that occur during stress and how mesenchymal stem cells complement the rescue of neuronal cell death mediated by [Ca2+]i and reactive oxygen species.
Thu Dec 06 00:00:00 EST 2018
Tubulin Beta-3 Chain as a New Candidate Protein Biomarker of Human Skin Aging: A Preliminary Study.
Oxidative medicine and cellular longevity
Lehmann SG,Bourgoin-Voillard S,Seve M,Rachidi W
Published figure using beta-3 Tubulin monoclonal antibody (Product # MA1-118) in Western Blot
Mon Mar 19 00:00:00 EDT 2018
Sustained Subconjunctival Delivery of Infliximab Protects the Cornea and Retina Following Alkali Burn to the Eye.
Investigative ophthalmology & visual science
Zhou C,Robert MC,Kapoulea V,Lei F,Stagner AM,Jakobiec FA,Dohlman CH,Paschalis EI
MA1-118 was used in immunohistochemistry - frozen section to evaluate the efficacy of subconjunctival delivery of TNF-alpha antibodies using a polymer-based drug delivery system
Sun Jan 01 00:00:00 EST 2017
Mycolactone displays anti-inflammatory effects on the nervous system.
PLoS neglected tropical diseases
Isaac C,Mauborgne A,Grimaldi A,Ade K,Pohl M,Limatola C,Boucher Y,Demangel C,Guenin-Macé L
MA1-118 was used in Immunohistochemistry to provide in vitro and vivo evidence that mycolactone suppresses: sensory neurons, Schwann cells and microglia inflammatory responses, without affecting cell viability.
Wed Nov 01 00:00:00 EDT 2017
Mycolactone displays anti-inflammatory effects on the nervous system.
PLoS neglected tropical diseases
Isaac C,Mauborgne A,Grimaldi A,Ade K,Pohl M,Limatola C,Boucher Y,Demangel C,Guenin-Macé L
MA1-118 was used in Immunohistochemistry to provide in vitro and vivo evidence that mycolactone suppresses: sensory neurons, Schwann cells and microglia inflammatory responses, without affecting cell viability.
Wed Nov 01 00:00:00 EDT 2017
