Product References
Engineered bone marrow as a clinically relevant ex vivo model for primary bone cancer research and drug screening.
Proceedings of the National Academy of Sciences of the United States of America
Griffin KH,Thorpe SW,Sebastian A,Hum NR,Coonan TP,Sagheb IS,Loots GG,Randall RL,Leach JK
Published figure using Ly-6A/E (Sca-1) monoclonal antibody (Product # 56-5981-82) in Flow Cytometry
Tue Sep 26 00:00:00 EDT 2023
STS1 and STS2 Phosphatase Inhibitor Baicalein Enhances the Expansion of Hematopoietic and Progenitor Stem Cells and Alleviates 5-Fluorouracil-Induced Myelosuppression.
International journal of molecular sciences
Li N,Wang Y,Wang A,Zhang J,Jia C,Yu C,Song Z,Wang S,Liu L,Yi J,Bao Y,Huang Y,Sun L
Published figure using Ly-6A/E (Sca-1) monoclonal antibody (Product # 56-5981-82) in Flow Cytometry
Fri Feb 03 00:00:00 EST 2023
Stromal niche inflammation mediated by IL-1 signalling is a targetable driver of haematopoietic ageing.
Nature cell biology
Mitchell CA,Verovskaya EV,Calero-Nieto FJ,Olson OC,Swann JW,Wang X,Hérault A,Dellorusso PV,Zhang SY,Svendsen AF,Pietras EM,Bakker ST,Ho TT,Göttgens B,Passegué E
56-5981-82 was used in Flow cytometry/Cell sorting to characterize the inflammatory milieu that drives both niche and haematopoietic remodelling.
Sun Jan 01 00:00:00 EST 2023
The extracellular matrix controls stem cell specification and crypt morphology in the developing and adult mouse gut.
Biology open
Ramadan R,Wouters VM,van Neerven SM,de Groot NE,Garcia TM,Muncan V,Franklin OD,Battle M,Carlson KS,Leach J,Sansom OJ,Boulard O,Chamaillard M,Vermeulen L,Medema JP,Huels DJ
Published figure using Ly-6A/E (Sca-1) monoclonal antibody (Product # 56-5981-82) in Flow Cytometry
Thu Dec 15 00:00:00 EST 2022
The extracellular matrix controls stem cell specification and crypt morphology in the developing and adult mouse gut.
Biology open
Ramadan R,Wouters VM,van Neerven SM,de Groot NE,Garcia TM,Muncan V,Franklin OD,Battle M,Carlson KS,Leach J,Sansom OJ,Boulard O,Chamaillard M,Vermeulen L,Medema JP,Huels DJ
Published figure using Ly-6A/E (Sca-1) monoclonal antibody (Product # 56-5981-82) in Flow Cytometry
Thu Dec 15 00:00:00 EST 2022
Cardiac Mesenchymal Stem Cells Promote Fibrosis and Remodeling in Heart Failure: Role of PDGF Signaling.
JACC. Basic to translational science
Hamid T,Xu Y,Ismahil MA,Rokosh G,Jinno M,Zhou G,Wang Q,Prabhu SD
Published figure using Ly-6A/E (Sca-1) monoclonal antibody (Product # 56-5981-82) in Flow Cytometry
Sun May 01 00:00:00 EDT 2022
Hematopoietic-Mesenchymal Signals Regulate the Properties of Mesenchymal Stem Cells.
International journal of molecular sciences
Kanazawa S,Okada H,Riu D,Mabuchi Y,Akazawa C,Iwata J,Hoshi K,Hikita A
Published figure using Ly-6A/E (Sca-1) monoclonal antibody (Product # 56-5981-82) in Flow Cytometry
Tue Jul 26 00:00:00 EDT 2022
Dynamic and adaptive cancer stem cell population admixture in colorectal neoplasia.
Cell stem cell
Vasquez EG,Nasreddin N,Valbuena GN,Mulholland EJ,Belnoue-Davis HL,Eggington HR,Schenck RO,Wouters VM,Wirapati P,Gilroy K,Lannagan TRM,Flanagan DJ,Najumudeen AK,Omwenga S,McCorry AMB,Easton A,Koelzer VH,East JE,Morton D,Trusolino L,Maughan T,Campbell AD,Loughrey MB,Dunne PD,Tsantoulis P,Huels DJ,Tejpar S,Sansom OJ,Leedham SJ
Published figure using Ly-6A/E (Sca-1) monoclonal antibody (Product # 56-5981-82) in Flow Cytometry
Thu Aug 04 00:00:00 EDT 2022
Hedgehog Signaling in Papillary Fibroblasts Is Essential for Hair Follicle Regeneration during Wound Healing.
The Journal of investigative dermatology
Frech S,Forsthuber A,Korosec A,Lipp K,Kozumov V,Lichtenberger BM
56-5981-82 was used in flow cytometry to investigate signalling in hair follicle regeneration.
Wed Jun 01 00:00:00 EDT 2022
Nociceptive nerves regulate haematopoietic stem cell mobilization.
Nature
Gao X,Zhang D,Xu C,Li H,Caron KM,Frenette PS
Published figure using Ly-6A/E (Sca-1) monoclonal antibody (Product # 56-5981-82) in Flow Cytometry
Fri Jan 01 00:00:00 EST 2021
Photoreceptor protection by mesenchymal stem cell transplantation identifies exosomal MiR-21 as a therapeutic for retinal degeneration.
Cell death and differentiation
Deng CL,Hu CB,Ling ST,Zhao N,Bao LH,Zhou F,Xiong YC,Chen T,Sui BD,Yu XR,Hu CH
Published figure using Ly-6A/E (Sca-1) monoclonal antibody (Product # 56-5981-82) in Flow Cytometry
Mon Mar 01 00:00:00 EST 2021
Loss of p53 in mesenchymal stem cells promotes alteration of bone remodeling through negative regulation of osteoprotegerin.
Cell death and differentiation
Velletri T,Huang Y,Wang Y,Li Q,Hu M,Xie N,Yang Q,Chen X,Chen Q,Shou P,Gan Y,Candi E,Annicchiarico-Petruzzelli M,Agostini M,Yang H,Melino G,Shi Y,Wang Y
Published figure using Ly-6A/E (Sca-1) monoclonal antibody (Product # 56-5981-82) in Flow Cytometry
Fri Jan 01 00:00:00 EST 2021
RANKL from bone marrow adipose lineage cells promotes osteoclast formation and bone loss.
EMBO reports
Hu Y,Li X,Zhi X,Cong W,Huang B,Chen H,Wang Y,Li Y,Wang L,Fang C,Guo J,Liu Y,Cui J,Cao L,Weng W,Zhou Q,Wang S,Chen X,Su J
Published figure using Ly-6A/E (Sca-1) monoclonal antibody (Product # 56-5981-82) in Flow Cytometry
Mon Jul 05 00:00:00 EDT 2021
Effects of signaling pathway inhibitors on hematopoietic stem cells.
Molecular medicine reports
Jiang Y,Xu Z,Ma N,Yin L,Hao C,Li J
Published figure using Ly-6A/E (Sca-1) monoclonal antibody (Product # 56-5981-82) in Flow Cytometry
Fri Jan 01 00:00:00 EST 2021
Age-related trabecular bone loss is associated with a decline in serum Galectin-1 level.
BMC musculoskeletal disorders
Xu W,Ni C,Wang Y,Zheng G,Zhang J,Xu Y
Published figure using Ly-6A/E (Sca-1) monoclonal antibody (Product # 56-5981-82) in Flow Cytometry
Tue Apr 27 00:00:00 EDT 2021
Differential activation of Ca2+ influx channels modulate stem cell potency, their proliferation/viability and tissue regeneration.
NPJ Regenerative medicine
Ahamad N,Sun Y,Nascimento Da Conceicao V,Xavier Paul Ezhilan CRD,Natarajan M,Singh BB
Published figure using Ly-6A/E (Sca-1) monoclonal antibody (Product # 56-5981-82) in Immunohistochemistry
Wed Oct 20 00:00:00 EDT 2021
The IRE1/XBP1 signaling axis promotes skeletal muscle regeneration through a cell non-autonomous mechanism.
eLife
Roy A,Tomaz da Silva M,Bhat R,Bohnert KR,Iwawaki T,Kumar A
Published figure using Ly-6A/E (Sca-1) monoclonal antibody (Product # 56-5981-82) in Flow Cytometry
Tue Nov 23 00:00:00 EST 2021
Conditionally pathogenic genetic variants of a hematopoietic disease-suppressing enhancer.
Science advances
Soukup AA,Matson DR,Liu P,Johnson KD,Bresnick EH
Published figure using Ly-6A/E (Sca-1) monoclonal antibody (Product # 56-5981-82) in Flow Cytometry
Fri Dec 10 00:00:00 EST 2021
Therapeutic Potential of Mesenchymal Stem Cells in a Pre-Clinical Model of Diabetic Kidney Disease and Obesity.
International journal of molecular sciences
Sávio-Silva C,Soinski-Sousa PE,Simplício-Filho A,Bastos RMC,Beyerstedt S,Rangel ÉB
Published figure using Ly-6A/E (Sca-1) monoclonal antibody (Product # 56-5981-82) in Flow Cytometry
Thu Feb 04 00:00:00 EST 2021
Troy/Tnfrsf19 marks epidermal cells that govern interfollicular epidermal renewal and cornification.
Stem cell reports
Kretzschmar K,Boonekamp KE,Bleijs M,Asra P,Koomen M,Chuva de Sousa Lopes SM,Giovannone B,Clevers H
Published figure using Ly-6A/E (Sca-1) monoclonal antibody (Product # 56-5981-82) in Flow Cytometry
Tue Sep 14 00:00:00 EDT 2021
Activation of skeletal muscle-resident glial cells upon nerve injury.
JCI insight
Proietti D,Giordani L,De Bardi M,D'Ercole C,Lozanoska-Ochser B,Amadio S,Volonté C,Marinelli S,Muchir A,Bouché M,Borsellino G,Sacco A,Puri PL,Madaro L
Published figure using Ly-6A/E (Sca-1) monoclonal antibody (Product # 56-5981-82) in Flow Cytometry
Thu Apr 08 00:00:00 EDT 2021
MAEA is an E3 ubiquitin ligase promoting autophagy and maintenance of haematopoietic stem cells.
Nature communications
Wei Q,Pinho S,Dong S,Pierce H,Li H,Nakahara F,Xu J,Xu C,Boulais PE,Zhang D,Maryanovich M,Cuervo AM,Frenette PS
Published figure using Ly-6A/E (Sca-1) monoclonal antibody (Product # 56-5981-82) in Flow Cytometry
Tue May 04 00:00:00 EDT 2021
Heterogeneity of murine periosteum progenitors involved in fracture healing.
eLife
Matthews BG,Novak S,Sbrana FV,Funnell JL,Cao Y,Buckels EJ,Grcevic D,Kalajzic I
56-5981-82 was used in Flow Cytometry to demonstrate that the periosteum is highly enriched with skeletal progenitor cells, and there is heterogeneity in the populations of cells that contribute to mature lineages during periosteal fracture healing.
Tue Feb 09 00:00:00 EST 2021
Muscle regeneration controlled by a designated DNA dioxygenase.
Cell death & disease
Wang H,Huang Y,Yu M,Yu Y,Li S,Wang H,Sun H,Li B,Xu G,Hu P
56-5981-82 was used in Flow Cytometry to define the function of Tet proteins in in vivo muscle regeneration.
Tue May 25 00:00:00 EDT 2021
Distinct skeletal stem cell types orchestrate long bone skeletogenesis.
eLife
Ambrosi TH,Sinha R,Steininger HM,Hoover MY,Murphy MP,Koepke LS,Wang Y,Lu WJ,Morri M,Neff NF,Weissman IL,Longaker MT,Chan CK
56-5981-82 was used in Flow Cytometry to address previously unappreciated shortcomings of SSC research.
Mon Jul 19 00:00:00 EDT 2021
Myofiber necroptosis promotes muscle stem cell proliferation via releasing Tenascin-C during regeneration.
Cell research
Zhou S,Zhang W,Cai G,Ding Y,Wei C,Li S,Yang Y,Qin J,Liu D,Zhang H,Shao X,Wang J,Wang H,Yang W,Wang H,Chen S,Hu P,Sun L
56-5981 was used in Flow cytometry/Cell sorting to indicate that necroptosis plays a key role in promoting MuSC proliferation to facilitate muscle regeneration.
Tue Dec 01 00:00:00 EST 2020
Snai2 Maintains Bone Marrow Niche Cells by Repressing Osteopontin Expression.
Developmental cell
Wei Q,Nakahara F,Asada N,Zhang D,Gao X,Xu C,Alfieri A,Brodin NP,Zimmerman SE,Mar JC,Guha C,Guo W,Frenette PS
56-5981-82 was used in Flow Cytometry to conclude that SNAI2 is a critical regulator of the transcriptional network maintaining MSPCs by the suppression of osteopontin expression.
Mon Jun 08 00:00:00 EDT 2020
Epigenetic Regulation of TLR4 in Diabetic Macrophages Modulates Immunometabolism and Wound Repair.
Journal of immunology (Baltimore, Md. : 1950)
Davis FM,denDekker A,Kimball A,Joshi AD,El Azzouny M,Wolf SJ,Obi AT,Lipinski J,Gudjonsson JE,Xing X,Plazyo O,Audu C,Melvin WJ,Singer K,Henke PK,Moore BB,Burant C,Kunkel SL,Gallagher KA
56-5981 was used in Flow cytometry/Cell sorting to define an important role for MLL1-mediated epigenetic regulation of TLR4 in pathologic diabetic wound repair and suggest a target for therapeutic manipulation.
Fri May 01 00:00:00 EDT 2020
Site-1 protease ablation in the osterix-lineage in mice results in bone marrow neutrophilia and hematopoietic stem cell alterations.
Biology open
Patra D,Kim J,Zhang Q,Tycksen E,Sandell LJ
56-5981 was used in Flow cytometry/Cell sorting to show that S1P has a role in the lineage specification of hematopoietic stem cells and/or their progenitors for development of a normal hematopoietic niche.
Tue Jun 23 00:00:00 EDT 2020
Multipotency of mouse trophoblast stem cells.
Stem cell research & therapy
Hou M,Han J,Li G,Kwon MY,Jiang J,Emani S,Taglauer ES,Park JA,Choi EB,Vodnala M,Fong YW,Emani SM,Rosas IO,Perrella MA,Liu X
Published figure using Ly-6A/E (Sca-1) monoclonal antibody (Product # 56-5981-82) in Immunocytochemistry
Thu Feb 13 00:00:00 EST 2020
Multipotency of mouse trophoblast stem cells.
Stem cell research & therapy
Hou M,Han J,Li G,Kwon MY,Jiang J,Emani S,Taglauer ES,Park JA,Choi EB,Vodnala M,Fong YW,Emani SM,Rosas IO,Perrella MA,Liu X
Published figure using Ly-6A/E (Sca-1) monoclonal antibody (Product # 56-5981-82) in Immunocytochemistry
Thu Feb 13 00:00:00 EST 2020
Multipotency of mouse trophoblast stem cells.
Stem cell research & therapy
Hou M,Han J,Li G,Kwon MY,Jiang J,Emani S,Taglauer ES,Park JA,Choi EB,Vodnala M,Fong YW,Emani SM,Rosas IO,Perrella MA,Liu X
Published figure using Ly-6A/E (Sca-1) monoclonal antibody (Product # 56-5981-82) in Immunocytochemistry
Thu Feb 13 00:00:00 EST 2020
Diamond Blackfan anemia is mediated by hyperactive Nemo-like kinase.
Nature communications
Wilkes MC,Siva K,Chen J,Varetti G,Youn MY,Chae H,Ek F,Olsson R,Lundbäck T,Dever DP,Nishimura T,Narla A,Glader B,Nakauchi H,Porteus MH,Repellin CE,Gazda HT,Lin S,Serrano M,Flygare J,Sakamoto KM
Published figure using Ly-6A/E (Sca-1) monoclonal antibody (Product # 56-5981-82) in Flow Cytometry
Fri Jul 03 00:00:00 EDT 2020
XIAOPI formula inhibits the pre-metastatic niche formation in breast cancer via suppressing TAMs/CXCL1 signaling.
Cell communication and signaling : CCS
Zheng Y,Wang N,Wang S,Yang B,Situ H,Zhong L,Lin Y,Wang Z
Published figure using Ly-6A/E (Sca-1) monoclonal antibody (Product # 56-5981-82) in Flow Cytometry
Thu Mar 26 00:00:00 EDT 2020
Use of Busulfan to Condition Mice for Bone Marrow Transplantation.
STAR protocols
Montecino-Rodriguez E,Dorshkind K
Published figure using Ly-6A/E (Sca-1) monoclonal antibody (Product # 56-5981-82) in Flow Cytometry
Fri Dec 18 00:00:00 EST 2020
Interaction of Deubiquitinase 2A-DUB/MYSM1 with DNA Repair and Replication Factors.
International journal of molecular sciences
Kroeger C,Roesler R,Wiese S,Hainzl A,Gatzka MV
Published figure using Ly-6A/E (Sca-1) monoclonal antibody (Product # 56-5981-82) in Flow Cytometry
Tue May 26 00:00:00 EDT 2020
A novel function of R-spondin1 in regulating estrogen receptor expression independent of Wnt/β-catenin signaling.
eLife
Geng A,Wu T,Cai C,Song W,Wang J,Yu QC,Zeng YA
Published figure using Ly-6A/E (Sca-1) monoclonal antibody (Product # 56-5981-82) in Flow Cytometry
Tue Aug 04 00:00:00 EDT 2020
Apoptotic bodies derived from mesenchymal stem cells promote cutaneous wound healing via regulating the functions of macrophages.
Stem cell research & therapy
Liu J,Qiu X,Lv Y,Zheng C,Dong Y,Dou G,Zhu B,Liu A,Wang W,Zhou J,Liu S,Liu S,Gao B,Jin Y
Published figure using Ly-6A/E (Sca-1) monoclonal antibody (Product # 56-5981-82) in Flow Cytometry
Fri Nov 27 00:00:00 EST 2020
Phosphatase SHP1 impedes mesenchymal stromal cell immunosuppressive capacity modulated by JAK1/STAT3 and P38 signals.
Cell & bioscience
Jiang M,Ye J,Wang X,Li N,Wang Y,Shi Y
Published figure using Ly-6A/E (Sca-1) monoclonal antibody (Product # 56-5981-82) in Flow Cytometry
Thu Apr 14 00:00:00 EDT 2022
Modest Declines in Proteome Quality Impair Hematopoietic Stem Cell Self-Renewal.
Cell reports
Hidalgo San Jose L,Sunshine MJ,Dillingham CH,Chua BA,Kruta M,Hong Y,Hatters DM,Signer RAJ
56-5981 was used in Flow cytometry/Cell sorting to show that hematopoietic stem cells (HSCs) are dependent on low protein synthesis to maintain proteostasis, which promotes their self-renewal.
Tue Jan 07 00:00:00 EST 2020
The micropeptide LEMP plays an evolutionarily conserved role in myogenesis.
Cell death & disease
Wang L,Fan J,Han L,Qi H,Wang Y,Wang H,Chen S,Du L,Li S,Zhang Y,Tang W,Ge G,Pan W,Hu P,Cheng H
56-5981 was used in Flow cytometry/Cell sorting to uncover a micropeptide that plays an evolutionarily conserved role in skeletal muscle differentiation, pinpointing the functional importance of this growing family of small peptides.
Mon May 11 00:00:00 EDT 2020
miR-142 induces accumulation of reactive oxygen species (ROS) by inhibiting pexophagy in aged bone marrow mesenchymal stem cells.
Scientific reports
Houri K,Mori T,Onodera Y,Tsujimoto T,Takehara T,Nakao S,Teramura T,Fukuda K
Published figure using Ly-6A/E (Sca-1) monoclonal antibody (Product # 56-5981-82) in Flow Cytometry
Fri Feb 28 00:00:00 EST 2020
An Id2RFP-Reporter Mouse Redefines Innate Lymphoid Cell Precursor Potentials.
Immunity
Xu W,Cherrier DE,Chea S,Vosshenrich C,Serafini N,Petit M,Liu P,Golub R,Di Santo JP
56-5981 was used in Flow cytometry/Cell sorting to suggest a revised model for ILC differentiation that redefines the cell-fate potential of helper-ILC-restricted Zbtb16+ ILCPs.
Tue Apr 16 00:00:00 EDT 2019
Long-term expansion and differentiation of adult murine epidermal stem cells in 3D organoid cultures.
Proceedings of the National Academy of Sciences of the United States of America
Boonekamp KE,Kretzschmar K,Wiener DJ,Asra P,Derakhshan S,Puschhof J,López-Iglesias C,Peters PJ,Basak O,Clevers H
Published figure using Ly-6A/E (Sca-1) monoclonal antibody (Product # 56-5981-82) in Flow Cytometry
Tue Jul 16 00:00:00 EDT 2019
PDGFRA defines the mesenchymal stem cell Kaposi's sarcoma progenitors by enabling KSHV oncogenesis in an angiogenic environment.
PLoS pathogens
Naipauer J,Rosario S,Gupta S,Premer C,Méndez-Solís O,Schlesinger M,Ponzinibbio V,Jain V,Gay L,Renne R,Chan HL,Morey L,Salyakina D,Abba M,Williams S,Hare JM,Goldschmidt-Clermont PJ,Mesri EA
Published figure using Ly-6A/E (Sca-1) monoclonal antibody (Product # 56-5981-82) in Flow Cytometry
Sun Dec 01 00:00:00 EST 2019
Transforming Growth Factor β-Activated Kinase 1 Regulates Mesenchymal Stem Cell Proliferation Through Stabilization of Yap1/Taz Proteins.
Stem cells (Dayton, Ohio)
Onodera Y,Teramura T,Takehara T,Fukuda K
Published figure using Ly-6A/E (Sca-1) monoclonal antibody (Product # 56-5981-82) in Flow Cytometry
Sun Dec 01 00:00:00 EST 2019
Pharmacological exposures may precipitate craniosynostosis through targeted stem cell depletion.
Stem cell research
Durham E,Howie RN,Larson N,LaRue A,Cray J
Published figure using Ly-6A/E (Sca-1) monoclonal antibody (Product # 56-5981-82) in Flow Cytometry
Tue Oct 01 00:00:00 EDT 2019
Macrophages fine tune satellite cell fate in dystrophic skeletal muscle of mdx mice.
PLoS genetics
Madaro L,Torcinaro A,De Bardi M,Contino FF,Pelizzola M,Diaferia GR,Imeneo G,Bouchè M,Puri PL,De Santa F
Published figure using Ly-6A/E (Sca-1) monoclonal antibody (Product # 56-5981-82) in Flow Cytometry
Tue Oct 01 00:00:00 EDT 2019
TGFβ-induced degradation of TRAF3 in mesenchymal progenitor cells causes age-related osteoporosis.
Nature communications
Li J,Ayoub A,Xiu Y,Yin X,Sanders JO,Mesfin A,Xing L,Yao Z,Boyce BF
Published figure using Ly-6A/E (Sca-1) monoclonal antibody (Product # 56-5981-82) in Flow Cytometry
Wed Jun 26 00:00:00 EDT 2019
Excessive exosome release is the pathogenic pathway linking a lysosomal deficiency to generalized fibrosis.
Science advances
van de Vlekkert D,Demmers J,Nguyen XX,Campos Y,Machado E,Annunziata I,Hu H,Gomero E,Qiu X,Bongiovanni A,Feghali-Bostwick CA,d'Azzo A
Published figure using Ly-6A/E (Sca-1) monoclonal antibody (Product # 56-5981-82) in Flow Cytometry
Mon Jul 01 00:00:00 EDT 2019
The microRNAs miR-204 and miR-211 maintain joint homeostasis and protect against osteoarthritis progression.
Nature communications
Huang J,Zhao L,Fan Y,Liao L,Ma PX,Xiao G,Chen D
Published figure using Ly-6A/E (Sca-1) monoclonal antibody (Product # 56-5981-82) in Flow Cytometry
Fri Jun 28 00:00:00 EDT 2019
Procr-expressing progenitor cells are responsible for murine ovulatory rupture repair of ovarian surface epithelium.
Nature communications
Wang J,Wang D,Chu K,Li W,Zeng YA
Published figure using Ly-6A/E (Sca-1) monoclonal antibody (Product # 56-5981-82) in Flow Cytometry
Thu Oct 31 00:00:00 EDT 2019
Improving the Accuracy of Flow Cytometric Assessment of Mitochondrial Membrane Potential in Hematopoietic Stem and Progenitor Cells Through the Inhibition of Efflux Pumps.
Journal of visualized experiments : JoVE
Morganti C,Bonora M,Ito K
Published figure using Ly-6A/E (Sca-1) monoclonal antibody (Product # 56-5981-82) in Flow Cytometry
Tue Jul 30 00:00:00 EDT 2019
Breast Tumor Cells Highly Resistant to Drugs Are Controlled Only by the Immune Response Induced in an Immunocompetent Mouse Model.
Integrative cancer therapies
Lasso P,Llano Murcia M,Sandoval TA,Urueña C,Barreto A,Fiorentino S
Published figure using Ly-6A/E (Sca-1) monoclonal antibody (Product # 56-5981-82) in Flow Cytometry
Wed Dec 11 00:00:00 EST 2019
Nidogen-1 Contributes to the Interaction Network Involved in Pro-B Cell Retention in the Peri-sinusoidal Hematopoietic Stem Cell Niche.
Cell reports
Balzano M,De Grandis M,Vu Manh TP,Chasson L,Bardin F,Farina A,Sergé A,Bidaut G,Charbord P,Hérault L,Bailly AL,Cartier-Michaud A,Boned A,Dalod M,Duprez E,Genever P,Coles M,Bajenoff M,Xerri L,Aurrand-Lions M,Schiff C,Mancini SJC
56-5981 was used in Flow cytometry/Cell sorting to study pro-B cells in their support of stroll cells and their interaction network allowing their retention.
Tue Mar 19 00:00:00 EDT 2019
Large-Scale Clonal Analysis Resolves Aging of the Mouse Hematopoietic Stem Cell Compartment.
Cell stem cell
Yamamoto R,Wilkinson AC,Ooehara J,Lan X,Lai CY,Nakauchi Y,Pritchard JK,Nakauchi H
56-5981 was used in Flow cytometry/Cell sorting to determine the age-related functional changes to the haematopoietic stem cell compartment.
Thu Apr 05 00:00:00 EDT 2018
Cited4 is a sex-biased mediator of the antidiabetic glitazone response in adipocyte progenitors.
EMBO molecular medicine
Bayindir-Buchhalter I,Wolff G,Lerch S,Sijmonsma T,Schuster M,Gronych J,Billeter AT,Babaei R,Krunic D,Ketscher L,Spielmann N,Hrabe de Angelis M,Ruas JL,Müller-Stich BP,Heikenwalder M,Lichter P,Herzig S,Vegiopoulos A
56-5981 was used in Flow cytometry/Cell sorting to reveal novel unexpected aspects of the pharmacological targeting of PPARg.
Wed Aug 01 00:00:00 EDT 2018
Spatial and Single-Cell Transcriptional Profiling Identifies Functionally Distinct Human Dermal Fibroblast Subpopulations.
The Journal of investigative dermatology
Philippeos C,Telerman SB,Oulès B,Pisco AO,Shaw TJ,Elgueta R,Lombardi G,Driskell RR,Soldin M,Lynch MD,Watt FM
56-5981 was used in Flow cytometry/Cell sorting to suggest that ex vivo expansion or in vivo ablation of specific fibroblast subpopulations may have therapeutic applications in wound healing and diseases characterized by excessive fibrosis.
Sun Apr 01 00:00:00 EDT 2018
Cytokine- and TCR-Mediated Regulation of T Cell Expression of Ly6C and Sca-1.
Journal of immunology (Baltimore, Md. : 1950)
DeLong JH,Hall AO,Konradt C,Coppock GM,Park J,Harms Pritchard G,Hunter CA
Published figure using Ly-6A/E (Sca-1) monoclonal antibody (Product # 56-5981-82) in Flow Cytometry
Thu Mar 01 00:00:00 EST 2018
PDGF is a potent initiator of bone formation in a tissue engineered model of pathological ossification.
Journal of tissue engineering and regenerative medicine
Davies OG,Grover LM,Lewis MP,Liu Y
Published figure using Ly-6A/E (Sca-1) monoclonal antibody (Product # 56-5981-82) in Flow Cytometry
Mon Jan 01 00:00:00 EST 2018
The H3K4 methyltransferase Setd1b is essential for hematopoietic stem and progenitor cell homeostasis in mice.
eLife
Schmidt K,Zhang Q,Tasdogan A,Petzold A,Dahl A,Arneth BM,Slany R,Fehling HJ,Kranz A,Stewart AF,Anastassiadis K
Published figure using Ly-6A/E (Sca-1) monoclonal antibody (Product # 56-5981-82) in Flow Cytometry
Tue Jun 19 00:00:00 EDT 2018
Tracking of Adipose-Derived Mesenchymal Stromal/Stem Cells in a Model of Cisplatin-Induced Acute Kidney Injury: Comparison of Bioluminescence Imaging versus qRT-PCR.
International journal of molecular sciences
Schubert R,Sann J,Frueh JT,Ullrich E,Geiger H,Baer PC
Published figure using Ly-6A/E (Sca-1) monoclonal antibody (Product # 56-5981-82) in Flow Cytometry
Wed Aug 29 00:00:00 EDT 2018
Differential requirement of kindlin-3 for T cell progenitor homing to the non-vascularized and vascularized thymus.
eLife
Moretti FA,Klapproth S,Ruppert R,Margraf A,Weber J,Pick R,Scheiermann C,Sperandio M,Fässler R,Moser M
Published figure using Ly-6A/E (Sca-1) monoclonal antibody (Product # 56-5981-82) in Flow Cytometry
Thu Sep 06 00:00:00 EDT 2018
HMGB2 is a novel adipogenic factor that regulates ectopic fat infiltration in skeletal muscles.
Scientific reports
Lee D,Taniguchi N,Sato K,Choijookhuu N,Hishikawa Y,Kataoka H,Morinaga H,Lotz M,Chosa E
Published figure using Ly-6A/E (Sca-1) monoclonal antibody (Product # 56-5981-82) in Flow Cytometry
Mon Jun 25 00:00:00 EDT 2018
Stem cell factor is selectively secreted by arterial endothelial cells in bone marrow.
Nature communications
Xu C,Gao X,Wei Q,Nakahara F,Zimmerman SE,Mar J,Frenette PS
Published figure using Ly-6A/E (Sca-1) monoclonal antibody (Product # 56-5981-82) in Flow Cytometry
Fri Jun 22 00:00:00 EDT 2018
Stem cell factor is selectively secreted by arterial endothelial cells in bone marrow.
Nature communications
Xu C,Gao X,Wei Q,Nakahara F,Zimmerman SE,Mar J,Frenette PS
Published figure using Ly-6A/E (Sca-1) monoclonal antibody (Product # 56-5981-82) in Flow Cytometry
Fri Jun 22 00:00:00 EDT 2018
RhoA, Rac1, and Cdc42 differentially regulate αSMA and collagen I expression in mesenchymal stem cells.
The Journal of biological chemistry
Ge J,Burnier L,Adamopoulou M,Kwa MQ,Schaks M,Rottner K,Brakebusch C
Published figure using Ly-6A/E (Sca-1) monoclonal antibody (Product # 56-5981-82) in Flow Cytometry
Fri Jun 15 00:00:00 EDT 2018
Bone marrow-derived immature myeloid cells are a main source of circulating suPAR contributing to proteinuric kidney disease.
Nature medicine
Hahm E,Wei C,Fernandez I,Li J,Tardi NJ,Tracy M,Wadhwani S,Cao Y,Peev V,Zloza A,Lusciks J,Hayek SS,O'Connor C,Bitzer M,Gupta V,Sever S,Sykes DB,Scadden DT,Reiser J
Published figure using Ly-6A/E (Sca-1) monoclonal antibody (Product # 56-5981-82) in Flow Cytometry
Sun Jan 01 00:00:00 EST 2017
Adipocyte Accumulation in the Bone Marrow during Obesity and Aging Impairs Stem Cell-Based Hematopoietic and Bone Regeneration.
Cell stem cell
Ambrosi TH,Scialdone A,Graja A,Gohlke S,Jank AM,Bocian C,Woelk L,Fan H,Logan DW,Schürmann A,Saraiva LR,Schulz TJ
56-5981 was used in Flow cytometry/Cell sorting to specify the cellular identities of the adipogenic and osteogenic lineages of the bone.
Thu Jun 01 00:00:00 EDT 2017
FOXP1 controls mesenchymal stem cell commitment and senescence during skeletal aging.
The Journal of clinical investigation
Li H,Liu P,Xu S,Li Y,Dekker JD,Li B,Fan Y,Zhang Z,Hong Y,Yang G,Tang T,Ren Y,Tucker HO,Yao Z,Guo X
Published figure using Ly-6A/E (Sca-1) monoclonal antibody (Product # 56-5981-82) in Flow Cytometry
Mon Apr 03 00:00:00 EDT 2017
GATA4-dependent organ-specific endothelial differentiation controls liver development and embryonic hematopoiesis.
The Journal of clinical investigation
Géraud C,Koch PS,Zierow J,Klapproth K,Busch K,Olsavszky V,Leibing T,Demory A,Ulbrich F,Diett M,Singh S,Sticht C,Breitkopf-Heinlein K,Richter K,Karppinen SM,Pihlajaniemi T,Arnold B,Rodewald HR,Augustin HG,Schledzewski K,Goerdt S
Published figure using Ly-6A/E (Sca-1) monoclonal antibody (Product # 56-5981-82) in Flow Cytometry
Wed Mar 01 00:00:00 EST 2017
Induced p53 loss in mouse luminal cells causes clonal expansion and development of mammary tumours.
Nature communications
Tao L,Xiang D,Xie Y,Bronson RT,Li Z
Published figure using Ly-6A/E (Sca-1) monoclonal antibody (Product # 56-5981-82) in Flow Cytometry
Mon Feb 13 00:00:00 EST 2017
Mutant U2AF1-expressing cells are sensitive to pharmacological modulation of the spliceosome.
Nature communications
Shirai CL,White BS,Tripathi M,Tapia R,Ley JN,Ndonwi M,Kim S,Shao J,Carver A,Saez B,Fulton RS,Fronick C,O'Laughlin M,Lagisetti C,Webb TR,Graubert TA,Walter MJ
Published figure using Ly-6A/E (Sca-1) monoclonal antibody (Product # 56-5981-82) in Flow Cytometry
Mon Jan 09 00:00:00 EST 2017
Longitudinal intravital imaging of the femoral bone marrow reveals plasticity within marrow vasculature.
Nature communications
Reismann D,Stefanowski J,Günther R,Rakhymzhan A,Matthys R,Nützi R,Zehentmeier S,Schmidt-Bleek K,Petkau G,Chang HD,Naundorf S,Winter Y,Melchers F,Duda G,Hauser AE,Niesner RA
Mon Dec 18 00:00:00 EST 2017
Longitudinal intravital imaging of the femoral bone marrow reveals plasticity within marrow vasculature.
Nature communications
Reismann D,Stefanowski J,Günther R,Rakhymzhan A,Matthys R,Nützi R,Zehentmeier S,Schmidt-Bleek K,Petkau G,Chang HD,Naundorf S,Winter Y,Melchers F,Duda G,Hauser AE,Niesner RA
Mon Dec 18 00:00:00 EST 2017
Integrating Enhancer Mechanisms to Establish a Hierarchical Blood Development Program.
Cell reports
Mehta C,Johnson KD,Gao X,Ong IM,Katsumura KR,McIver SC,Ranheim EA,Bresnick EH
Published figure using Ly-6A/E (Sca-1) monoclonal antibody (Product # 56-5981-82) in Flow Cytometry
Tue Sep 19 00:00:00 EDT 2017
Microgrooved-surface topography enhances cellular division and proliferation of mouse bone marrow-derived mesenchymal stem cells.
PloS one
Chaudhary JK,Rath PC
Published figure using Ly-6A/E (Sca-1) monoclonal antibody (Product # 56-5981-82) in Flow Cytometry
Thu Oct 19 00:00:00 EDT 2017
Zoledronate suppressed angiogenesis and osteogenesis by inhibiting osteoclasts formation and secretion of PDGF-BB.
PloS one
Gao SY,Zheng GS,Wang L,Liang YJ,Zhang SE,Lao XM,Li K,Liao GQ
Published figure using Ly-6A/E (Sca-1) monoclonal antibody (Product # 56-5981-82) in Flow Cytometry
Mon Sep 18 00:00:00 EDT 2017
The Deubiquitinase OTULIN Is an Essential Negative Regulator of Inflammation and Autoimmunity.
Cell
Damgaard RB,Walker JA,Marco-Casanova P,Morgan NV,Titheradge HL,Elliott PR,McHale D,Maher ER,McKenzie ANJ,Komander D
Published figure using Ly-6A/E (Sca-1) monoclonal antibody (Product # 56-5981-82) in Flow Cytometry
Thu Aug 25 00:00:00 EDT 2016
Revisiting Cardiac Cellular Composition.
Circulation research
Pinto AR,Ilinykh A,Ivey MJ,Kuwabara JT,D'Antoni ML,Debuque R,Chandran A,Wang L,Arora K,Rosenthal NA,Tallquist MD
Published figure using Ly-6A/E (Sca-1) monoclonal antibody (Product # 56-5981-82) in Flow Cytometry
Fri Feb 05 00:00:00 EST 2016
β-Catenin Stabilization in Skin Fibroblasts Causes Fibrotic Lesions by Preventing Adipocyte Differentiation of the Reticular Dermis.
The Journal of investigative dermatology
Mastrogiannaki M,Lichtenberger BM,Reimer A,Collins CA,Driskell RR,Watt FM
56-5981 was used in Flow cytometry/Cell sorting to study how Wnt/β-catenin signalling may control adipogenic cell fate within the lower dermis, which potentially contributes to the pathogenesis of fibrotic skin diseases.
Wed Jun 01 00:00:00 EDT 2016
Induction of Indoleamine 2,3-dioxygenase by Pre-treatment with Poly(I:C) May Enhance the Efficacy of MSC Treatment in DSS-induced Colitis.
Immune network
Ryu DB,Lim JY,Lee SE,Park G,Min CK
56-5981 was used in Flow cytometry/Cell sorting to determine whether TLR ligands can enhance the therapeutic efficacy of mesenchymal stem cells for treating inflammatory disorders.
Thu Dec 01 00:00:00 EST 2016
Hedgehog-driven myogenic tumors recapitulate skeletal muscle cellular heterogeneity.
Experimental cell research
Hettmer S,Lin MM,Tchessalova D,Tortorici SJ,Castiglioni A,Desai T,Mao J,McMahon AP,Wagers AJ
Published figure using Ly-6A/E (Sca-1) monoclonal antibody (Product # 56-5981-82) in Flow Cytometry
Fri Jan 01 00:00:00 EST 2016
Identification of an epidermal keratinocyte AMPA glutamate receptor involved in dermatopathies associated with sensory abnormalities.
Pain reports
Cabañero D,Irie T,Celorrio M,Trousdale C,Owens DM,Virley D,Albrecht PJ,Caterina MJ,Rice FL,Morón JA
Published figure using Ly-6A/E (Sca-1) monoclonal antibody (Product # 56-5981-82) in Flow Cytometry
Thu Sep 01 00:00:00 EDT 2016
Identification of a CD133-CD55- population functions as a fetal common skeletal progenitor.
Scientific reports
Weng L,Hu X,Kumar B,Garcia M,Todorov I,Jung X,Marcucci G,Forman SJ,Chen CC
Published figure using Ly-6A/E (Sca-1) monoclonal antibody (Product # 56-5981-82) in Immunofluorescence
Thu Dec 08 00:00:00 EST 2016
Identification of a CD133-CD55- population functions as a fetal common skeletal progenitor.
Scientific reports
Weng L,Hu X,Kumar B,Garcia M,Todorov I,Jung X,Marcucci G,Forman SJ,Chen CC
Published figure using Ly-6A/E (Sca-1) monoclonal antibody (Product # 56-5981-82) in Immunofluorescence
Thu Dec 08 00:00:00 EST 2016
KLF4-dependent phenotypic modulation of smooth muscle cells has a key role in atherosclerotic plaque pathogenesis.
Nature medicine
Shankman LS,Gomez D,Cherepanova OA,Salmon M,Alencar GF,Haskins RM,Swiatlowska P,Newman AA,Greene ES,Straub AC,Isakson B,Randolph GJ,Owens GK
Published figure using Ly-6A/E (Sca-1) monoclonal antibody (Product # 56-5981-82) in Immunofluorescence
Mon Jun 01 00:00:00 EDT 2015
KLF4-dependent phenotypic modulation of smooth muscle cells has a key role in atherosclerotic plaque pathogenesis.
Nature medicine
Shankman LS,Gomez D,Cherepanova OA,Salmon M,Alencar GF,Haskins RM,Swiatlowska P,Newman AA,Greene ES,Straub AC,Isakson B,Randolph GJ,Owens GK
Published figure using Ly-6A/E (Sca-1) monoclonal antibody (Product # 56-5981-82) in Immunofluorescence
Mon Jun 01 00:00:00 EDT 2015
Rapid depot-specific activation of adipocyte precursor cells at the onset of obesity.
Nature cell biology
Jeffery E,Church CD,Holtrup B,Colman L,Rodeheffer MS
Published figure using Ly-6A/E (Sca-1) monoclonal antibody (Product # 56-5981-82) in Flow Cytometry
Wed Apr 01 00:00:00 EDT 2015
Cis-regulatory mechanisms governing stem and progenitor cell transitions.
Science advances
Johnson KD,Kong G,Gao X,Chang YI,Hewitt KJ,Sanalkumar R,Prathibha R,Ranheim EA,Dewey CN,Zhang J,Bresnick EH
Published figure using Ly-6A/E (Sca-1) monoclonal antibody (Product # 56-5981-82) in Flow Cytometry
Tue Sep 01 00:00:00 EDT 2015
The tRNA methyltransferase Dnmt2 is required for accurate polypeptide synthesis during haematopoiesis.
The EMBO journal
Tuorto F,Herbst F,Alerasool N,Bender S,Popp O,Federico G,Reitter S,Liebers R,Stoecklin G,Gröne HJ,Dittmar G,Glimm H,Lyko F
56-5981 was used in Flow cytometry/Cell sorting to demonstrate that Dnmt2 plays an important role in haematopoiesis.
Mon Sep 14 00:00:00 EDT 2015
Cellular and molecular characterization of human cardiac stem cells reveals key features essential for their function and safety.
Stem cells and development
Vahdat S,Mousavi SA,Omrani G,Gholampour M,Sotoodehnejadnematalahi F,Ghazizadeh Z,Gharechahi J,Baharvand H,Salekdeh GH,Aghdami N
Published figure using Ly-6A/E (Sca-1) monoclonal antibody (Product # 56-5981-82) in Flow Cytometry
Mon Jun 15 00:00:00 EDT 2015
Multi-Drug Resistance ABC Transporter Inhibition Enhances Murine Ventral Prostate Stem/Progenitor Cell Differentiation.
Stem cells and development
Samant MD,Jackson CM,Felix CL,Jones AJ,Goodrich DW,Foster BA,Huss WJ
Published figure using Ly-6A/E (Sca-1) monoclonal antibody (Product # 56-5981-82) in Flow Cytometry
Fri May 15 00:00:00 EDT 2015
Limited miR-17-92 overexpression drives hematologic malignancies.
Leukemia research
Danielson LS,Reavie L,Coussens M,Davalos V,Castillo-Martin M,Guijarro MV,Coffre M,Cordon-Cardo C,Aifantis I,Ibrahim S,Liu C,Koralov SB,Hernando E
Published figure using Ly-6A/E (Sca-1) monoclonal antibody (Product # 56-5981-82) in Flow Cytometry
Sun Mar 01 00:00:00 EST 2015
Cardiac-Specific Activation of IKK2 Leads to Defects in Heart Development and Embryonic Lethality.
PloS one
Kraut B,Maier HJ,Kókai E,Fiedler K,Boettger T,Illing A,Kostin S,Walther P,Braun T,Wirth T
Published figure using Ly-6A/E (Sca-1) monoclonal antibody (Product # 56-5981-82) in Immunofluorescence
Mon Jun 13 00:00:00 EDT 2016
Interleukin-17-producing innate lymphoid cells and the NLRP3 inflammasome facilitate obesity-associated airway hyperreactivity.
Nature medicine
Kim HY,Lee HJ,Chang YJ,Pichavant M,Shore SA,Fitzgerald KA,Iwakura Y,Israel E,Bolger K,Faul J,DeKruyff RH,Umetsu DT
56-5981 was used in Flow cytometry/Cell sorting to show that IL-17 producing innate lymphoid cells and the NLRP3 inflammasome facilitate obesity-associated airway hyperreactivity.
Wed Jan 01 00:00:00 EST 2014
Cardiogenic genes expressed in cardiac fibroblasts contribute to heart development and repair.
Circulation research
Furtado MB,Costa MW,Pranoto EA,Salimova E,Pinto AR,Lam NT,Park A,Snider P,Chandran A,Harvey RP,Boyd R,Conway SJ,Pearson J,Kaye DM,Rosenthal NA
Published figure using Ly-6A/E (Sca-1) monoclonal antibody (Product # 56-5981-82) in Flow Cytometry
Fri Apr 25 00:00:00 EDT 2014
WASH is required for the differentiation commitment of hematopoietic stem cells in a c-Myc-dependent manner.
The Journal of experimental medicine
Xia P,Wang S,Huang G,Zhu P,Li M,Ye B,Du Y,Fan Z
Published figure using Ly-6A/E (Sca-1) monoclonal antibody (Product # 56-5981-82) in Flow Cytometry
Mon Sep 22 00:00:00 EDT 2014
Overexpressing sonic hedgehog peptide restores periosteal bone formation in a murine bone allograft transplantation model.
Molecular therapy : the journal of the American Society of Gene Therapy
Huang C,Tang M,Yehling E,Zhang X
Published figure using Ly-6A/E (Sca-1) monoclonal antibody (Product # 56-5981-82) in Flow Cytometry
Sat Feb 01 00:00:00 EST 2014
Epidermal Wnt/β-catenin signaling regulates adipocyte differentiation via secretion of adipogenic factors.
Proceedings of the National Academy of Sciences of the United States of America
Donati G,Proserpio V,Lichtenberger BM,Natsuga K,Sinclair R,Fujiwara H,Watt FM
56-5981 was used in Flow cytometry/Cell sorting to elucidate the mechanisms by which the epidermis can regulate adipogenesis.
Tue Apr 15 00:00:00 EDT 2014
Epidermal Wnt/β-catenin signaling regulates adipocyte differentiation via secretion of adipogenic factors.
Proceedings of the National Academy of Sciences of the United States of America
Donati G,Proserpio V,Lichtenberger BM,Natsuga K,Sinclair R,Fujiwara H,Watt FM
56-5981 was used in Flow cytometry/Cell sorting to elucidate the mechanisms by which the epidermis can regulate adipogenesis.
Tue Apr 15 00:00:00 EDT 2014
Cell-autonomous heparanase modulates self-renewal and migration in bone marrow-derived mesenchymal stem cells.
Journal of biomedical science
Cheng CC,Lee YH,Lin SP,Huangfu WC,Liu IH
Published figure using Ly-6A/E (Sca-1) monoclonal antibody (Product # 56-5981-82) in Flow Cytometry
Thu Mar 13 00:00:00 EDT 2014
T helper cell IL-4 drives intestinal Th2 priming to oral peanut antigen, under the control of OX40L and independent of innate-like lymphocytes.
Mucosal immunology
Chu DK,Mohammed-Ali Z,Jiménez-Saiz R,Walker TD,Goncharova S,Llop-Guevara A,Kong J,Gordon ME,Barra NG,Gillgrass AE,Van Seggelen H,Khan WI,Ashkar AA,Bramson JL,Humbles AA,Kolbeck R,Waserman S,Jordana M
56-5981 was used in Flow cytometry/Cell sorting to reveal intestinal Th2 priming is initiated by an autocrine/paracrine acting CD4(+) Th cell-intrinsic IL-4 program that is controlled by DC OX40L.
Sat Nov 01 00:00:00 EDT 2014
Recruitment of bone marrow-derived cells to periodontal tissue defects.
Frontiers in cell and developmental biology
Kimura Y,Komaki M,Iwasaki K,Sata M,Izumi Y,Morita I
Published figure using Ly-6A/E (Sca-1) monoclonal antibody (Product # 56-5981-82) in Flow Cytometry
Mon Nov 03 00:00:00 EST 2014
Evidence for Transfer of Membranes from Mesenchymal Stem Cells to HL-1 Cardiac Cells.
Stem cells international
Boomsma RA,Geenen DL
Published figure using Ly-6A/E (Sca-1) monoclonal antibody (Product # 56-5981-82) in Flow Cytometry
Wed Oct 08 00:00:00 EDT 2014
Immunohistological localization of endogenous unlabeled stem cells in wounded skin.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society
Hong S,Alapure BV,Lu Y,Tian H,Wang Q
Published figure using Ly-6A/E (Sca-1) monoclonal antibody (Product # 56-5981-82) in Immunofluorescence
Tue Apr 01 00:00:00 EDT 2014
Amniotic fluid stem cells prevent follicle atresia and rescue fertility of mice with premature ovarian failure induced by chemotherapy.
PloS one
Xiao GY,Liu IH,Cheng CC,Chang CC,Lee YH,Cheng WT,Wu SC
Published figure using Ly-6A/E (Sca-1) monoclonal antibody (Product # 56-5981-82) in Flow Cytometry
Thu May 28 00:00:00 EDT 2015
Validation of the effects of TGF-β1 on tumor recurrence and prognosis through tumor retrieval and cell mechanical properties.
Cancer cell international
Wu TH,Chou YW,Chiu PH,Tang MJ,Hu CW,Yeh ML
Published figure using Ly-6A/E (Sca-1) monoclonal antibody (Product # 56-5981-82) in Flow Cytometry
Mon Mar 03 00:00:00 EST 2014
Distinct fibroblast lineages determine dermal architecture in skin development and repair.
Nature
Driskell RR,Lichtenberger BM,Hoste E,Kretzschmar K,Simons BD,Charalambous M,Ferron SR,Herault Y,Pavlovic G,Ferguson-Smith AC,Watt FM
56-5981 was used in Flow cytometry/Cell sorting to explain why wounding is linked to formation of ECM-rich scar tissue that lacks hair follicles.
Thu Dec 12 00:00:00 EST 2013
Notch2-dependent classical dendritic cells orchestrate intestinal immunity to attaching-and-effacing bacterial pathogens.
Nature immunology
Satpathy AT,Briseño CG,Lee JS,Ng D,Manieri NA,Kc W,Wu X,Thomas SR,Lee WL,Turkoz M,McDonald KG,Meredith MM,Song C,Guidos CJ,Newberry RD,Ouyang W,Murphy TL,Stappenbeck TS,Gommerman JL,Nussenzweig MC,Colonna M,Kopan R,Murphy KM
56-5981 was used in Flow cytometry/Cell sorting to elucidate the cellular source of essential IL-23 production required for the mucosal response to attaching-and-effacing bacterial infection.
Sun Sep 01 00:00:00 EDT 2013
A mouse model for inducible overexpression of Prdm14 results in rapid-onset and highly penetrant T-cell acute lymphoblastic leukemia (T-ALL).
Disease models & mechanisms
Carofino BL,Ayanga B,Justice MJ
Published figure using Ly-6A/E (Sca-1) monoclonal antibody (Product # 56-5981-82) in Flow Cytometry
Fri Nov 01 00:00:00 EDT 2013
Conditional deletion of Jak2 reveals an essential role in hematopoiesis throughout mouse ontogeny: implications for Jak2 inhibition in humans.
PloS one
Park SO,Wamsley HL,Bae K,Hu Z,Li X,Choe SW,Slayton WB,Oh SP,Wagner KU,Sayeski PP
56-5981 was used in Flow cytometry/Cell sorting to understand the role played by Jak2 at varying stages of prenatal and postnatal life.
Tue Sep 17 00:00:00 EDT 2013
Lunatic fringe deficiency cooperates with the Met/Caveolin gene amplicon to induce basal-like breast cancer.
Cancer cell
Xu K,Usary J,Kousis PC,Prat A,Wang DY,Adams JR,Wang W,Loch AJ,Deng T,Zhao W,Cardiff RD,Yoon K,Gaiano N,Ling V,Beyene J,Zacksenhaus E,Gridley T,Leong WL,Guidos CJ,Perou CM,Egan SE
Published figure using Ly-6A/E (Sca-1) monoclonal antibody (Product # 56-5981-82) in Flow Cytometry
Tue May 15 00:00:00 EDT 2012
Concomitant inactivation of Rb and E2f8 in hematopoietic stem cells synergizes to induce severe anemia.
Blood
Hu T,Ghazaryan S,Sy C,Wiedmeyer C,Chang V,Wu L
Published figure using Ly-6A/E (Sca-1) monoclonal antibody (Product # 56-5981-82) in Flow Cytometry
Thu May 10 00:00:00 EDT 2012
Cis-element mutated in GATA2-dependent immunodeficiency governs hematopoiesis and vascular integrity.
The Journal of clinical investigation
Johnson KD,Hsu AP,Ryu MJ,Wang J,Gao X,Boyer ME,Liu Y,Lee Y,Calvo KR,Keles S,Zhang J,Holland SM,Bresnick EH
Published figure using Ly-6A/E (Sca-1) monoclonal antibody (Product # 56-5981-82) in Flow Cytometry
Mon Oct 01 00:00:00 EDT 2012
Zbtb46 expression distinguishes classical dendritic cells and their committed progenitors from other immune lineages.
The Journal of experimental medicine
Satpathy AT,KC W,Albring JC,Edelson BT,Kretzer NM,Bhattacharya D,Murphy TL,Murphy KM
56-5981 was used in Flow cytometry/Cell sorting to identify Zbtb46 as a transcription factor selectively expressed by classical DCs and their committed progenitors.
Mon Jun 04 00:00:00 EDT 2012
CTC1 deletion results in defective telomere replication, leading to catastrophic telomere loss and stem cell exhaustion.
The EMBO journal
Gu P,Min JN,Wang Y,Huang C,Peng T,Chai W,Chang S
Published figure using Ly-6A/E (Sca-1) monoclonal antibody (Product # 56-5981-82) in Flow Cytometry
Wed May 16 00:00:00 EDT 2012
Spontaneous mutation of the Dock2 gene in Irf5-/- mice complicates interpretation of type I interferon production and antibody responses.
Proceedings of the National Academy of Sciences of the United States of America
Purtha WE,Swiecki M,Colonna M,Diamond MS,Bhattacharya D
56-5981 was used in Flow cytometry/Cell sorting to study the functional role of interferon regulatory factor-5 in human autoimmune disease pathogenesis.
Tue Apr 10 00:00:00 EDT 2012
Induction of cardiac myogenic lineage development differs between mesenchymal and satellite cells and is accelerated by bone morphogenetic protein-4.
Journal of molecular and cellular cardiology
Grajales L,García J,Geenen DL
Published figure using Ly-6A/E (Sca-1) monoclonal antibody (Product # 56-5981-82) in Flow Cytometry
Sat Sep 01 00:00:00 EDT 2012
Proteomic cornerstones of hematopoietic stem cell differentiation: distinct signatures of multipotent progenitors and myeloid committed cells.
Molecular & cellular proteomics : MCP
Klimmeck D,Hansson J,Raffel S,Vakhrushev SY,Trumpp A,Krijgsveld J
56-5981 was used in Flow cytometry/Cell sorting to discern the distinct signatures of multipotent progenitors and myeloid committed cells.
Wed Aug 01 00:00:00 EDT 2012
Innate lymphoid cells mediate influenza-induced airway hyper-reactivity independently of adaptive immunity.
Nature immunology
Chang YJ,Kim HY,Albacker LA,Baumgarth N,McKenzie AN,Smith DE,Dekruyff RH,Umetsu DT
Published figure using Ly-6A/E (Sca-1) monoclonal antibody (Product # 56-5981-82) in Flow Cytometry
Sun May 29 00:00:00 EDT 2011
Essential roles for Pot1b in HSC self-renewal and survival.
Blood
Wang Y,Shen MF,Chang S
Published figure using Ly-6A/E (Sca-1) monoclonal antibody (Product # 56-5981-82) in Flow Cytometry
Thu Dec 01 00:00:00 EST 2011
CD24-positive cells from normal adult mouse liver are hepatocyte progenitor cells.
Stem cells and development
Qiu Q,Hernandez JC,Dean AM,Rao PH,Darlington GJ
Published figure using Ly-6A/E (Sca-1) monoclonal antibody (Product # 56-5981-82) in Flow Cytometry
Thu Dec 01 00:00:00 EST 2011
Adipose-derived stem cells promote lymphangiogenesis in response to VEGF-C stimulation or TGF-β1 inhibition.
Future oncology (London, England)
Yan A,Avraham T,Zampell JC,Haviv YS,Weitman E,Mehrara BJ
Published figure using Ly-6A/E (Sca-1) monoclonal antibody (Product # 56-5981-82) in Flow Cytometry
Thu Dec 01 00:00:00 EST 2011
A high omega-3 fatty acid diet has different effects on early and late stage myeloid progenitors.
Lipids
Varney ME,Buchanan JT,Dementieva Y,Hardman WE,Sollars VE
Published figure using Ly-6A/E (Sca-1) monoclonal antibody (Product # 56-5981-82) in Flow Cytometry
Sat Jan 01 00:00:00 EST 2011
Wnt4 enhances murine hematopoietic progenitor cell expansion through a planar cell polarity-like pathway.
PloS one
Heinonen KM,Vanegas JR,Lew D,Krosl J,Perreault C
56-5981 was used in Flow cytometry/Cell sorting to establish a functional role for non-canonical Wnt signalling in hematopoiesis through a pathway involving Wnt4, Fz6, Rac1 and Jnk kinases.
Tue Apr 26 00:00:00 EDT 2011
Peripheral CD103+ dendritic cells form a unified subset developmentally related to CD8alpha+ conventional dendritic cells.
The Journal of experimental medicine
Edelson BT,KC W,Juang R,Kohyama M,Benoit LA,Klekotka PA,Moon C,Albring JC,Ise W,Michael DG,Bhattacharya D,Stappenbeck TS,Holtzman MJ,Sung SS,Murphy TL,Hildner K,Murphy KM
56-5981 was used in Flow cytometry/Cell sorting to study the relationship between nonlymphoid CD103-expressing dendritic cells (DCs) and other DC subsets.
Mon Apr 12 00:00:00 EDT 2010
Delayed enrichment of mesenchymal cells promotes cardiac lineage and calcium transient development.
Journal of molecular and cellular cardiology
Grajales L,García J,Banach K,Geenen DL
Published figure using Ly-6A/E (Sca-1) monoclonal antibody (Product # 56-5981-82) in Flow Cytometry
Thu Apr 01 00:00:00 EDT 2010
Wnt7a activates the planar cell polarity pathway to drive the symmetric expansion of satellite stem cells.
Cell stem cell
Le Grand F,Jones AE,Seale V,Scimè A,Rudnicki MA
Published figure using Ly-6A/E (Sca-1) monoclonal antibody (Product # 56-5981-82) in Flow Cytometry
Fri Jun 05 00:00:00 EDT 2009
Reporter gene-expressing bone marrow-derived stromal cells are immune-tolerated following implantation in the central nervous system of syngeneic immunocompetent mice.
BMC biotechnology
Bergwerf I,De Vocht N,Tambuyzer B,Verschueren J,Reekmans K,Daans J,Ibrahimi A,Van Tendeloo V,Chatterjee S,Goossens H,Jorens PG,Baekelandt V,Ysebaert D,Van Marck E,Berneman ZN,Linden AV,Ponsaerts P
Published figure using Ly-6A/E (Sca-1) monoclonal antibody (Product # 56-5981-82) in Immunohistochemistry
Wed Jan 07 00:00:00 EST 2009
Reporter gene-expressing bone marrow-derived stromal cells are immune-tolerated following implantation in the central nervous system of syngeneic immunocompetent mice.
BMC biotechnology
Bergwerf I,De Vocht N,Tambuyzer B,Verschueren J,Reekmans K,Daans J,Ibrahimi A,Van Tendeloo V,Chatterjee S,Goossens H,Jorens PG,Baekelandt V,Ysebaert D,Van Marck E,Berneman ZN,Linden AV,Ponsaerts P
Published figure using Ly-6A/E (Sca-1) monoclonal antibody (Product # 56-5981-82) in Immunohistochemistry
Wed Jan 07 00:00:00 EST 2009
