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IL17RA Antibody (MA5-52436) in Flow
Product Details
MA5-52436
Species Reactivity
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Conjugate
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Target Information
Interleukin 17A (IL-17A) is a proinflammatory cytokine secreted by activated T-lymphocytes. It is a potent inducer of the maturation of CD34-positive hematopoietic precursors into neutrophils. IL-17RA is a ubiquitous type I membrane glycoprotein that binds with low affinity to IL-17A and IL-17F. IL-17A and its receptor play a pathogenic role in many inflammatory and autoimmune diseases such as rheumatoid arthritis. Defects in IL-17RA are the cause of familial candidiasis type 5 (CANDF5) which is a rare disorder with altered immune responses and impaired clearance of fungal infections.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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References (0)
Bioinformatics
Protein Aliases: CD217; IL-17 receptor A; IL-17RA; Interleukin-17 receptor A; MGC10262
Gene Aliases: AW538159; Cdw217; Il17r; Il17ra; VDw217
UniProt ID: (Mouse) Q60943
Entrez Gene ID: (Mouse) 16172
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