Product References
Fasudil-modified macrophages reduce inflammation and regulate the immune response in experimental autoimmune encephalomyelitis.
Neural regeneration research
Liu C,Guo S,Liu R,Guo M,Wang Q,Chai Z,Xiao B,Ma C
Published figure using IL-17A monoclonal antibody (Product # 25-7177-82) in Flow Cytometry
Fri Mar 01 00:00:00 EST 2024
Fermented cordyceps powder alleviates silica-induced pulmonary inflammation and fibrosis in rats by regulating the Th immune response.
Chinese medicine
Pu S,Yang Z,Zhang X,Li M,Han N,Yang X,He J,Yu G,Meng X,Jia Q,Shao H
Published figure using IL-17A monoclonal antibody (Product # 25-7177-82) in Flow Cytometry
Thu Oct 12 00:00:00 EDT 2023
The Potential of Dendritic-Cell-Based Vaccines to Modulate Type 3 Innate Lymphoid Cell Populations.
International journal of molecular sciences
Chan L,Mehrani Y,Minott JA,Bridle BW,Karimi K
Published figure using IL-17A monoclonal antibody (Product # 25-7177-82) in Flow Cytometry
Thu Jan 26 00:00:00 EST 2023
SARS-CoV-2 spike protein promotes inflammatory cytokine activation and aggravates rheumatoid arthritis.
Cell communication and signaling : CCS
Lee AR,Woo JS,Lee SY,Lee YS,Jung J,Lee CR,Park SH,Cho ML
Published figure using IL-17A monoclonal antibody (Product # 25-7177-82) in Flow Cytometry
Thu Mar 02 00:00:00 EST 2023
EC-18 prevents autoimmune arthritis by suppressing inflammatory cytokines and osteoclastogenesis.
Arthritis research & therapy
Park JS,Yang SC,Jeong HY,Lee SY,Ryu JG,Choi JW,Kang HY,Kim SM,Hwang SH,Cho ML,Park SH
Published figure using IL-17A monoclonal antibody (Product # 25-7177-82) in Flow Cytometry
Thu Nov 17 00:00:00 EST 2022
Free Fatty Acid Receptor 4 (FFA4) Activation Ameliorates Imiquimod-Induced Psoriasis in Mice.
International journal of molecular sciences
Son SE,Koh JM,Im DS
Published figure using IL-17A monoclonal antibody (Product # 25-7177-82) in Flow Cytometry
Tue Apr 19 00:00:00 EDT 2022
Transcription factor RORα enforces stability of the Th17 cell effector program by binding to a Rorc cis-regulatory element.
Immunity
Hall JA,Pokrovskii M,Kroehling L,Kim BR,Kim SY,Wu L,Lee JY,Littman DR
Published figure using IL-17A monoclonal antibody (Product # 25-7177-82) in Flow Cytometry
Tue Nov 08 00:00:00 EST 2022
Genetic manipulation of the human gut bacterium Eggerthella lenta reveals a widespread family of transcriptional regulators.
Nature communications
Dong X,Guthrie BGH,Alexander M,Noecker C,Ramirez L,Glasser NR,Turnbaugh PJ,Balskus EP
Published figure using IL-17A monoclonal antibody (Product # 25-7177-82) in Flow Cytometry
Fri Dec 09 00:00:00 EST 2022
Lactate induces metabolic and epigenetic reprogramming of pro-inflammatory Th17 cells.
EMBO reports
Lopez Krol A,Nehring HP,Krause FF,Wempe A,Raifer H,Nist A,Stiewe T,Bertrams W,Schmeck B,Luu M,Leister H,Chung HR,Bauer UM,Adhikary T,Visekruna A
Published figure using IL-17A monoclonal antibody (Product # 25-7177-82) in Flow Cytometry
Tue Dec 06 00:00:00 EST 2022
Maternal gut bacteria drive intestinal inflammation in offspring with neurodevelopmental disorders by altering the chromatin landscape of CD4+ T cells.
Immunity
Kim E,Paik D,Ramirez RN,Biggs DG,Park Y,Kwon HK,Choi GB,Huh JR
25-7177-82 was used in flow cytometry experiments to investigate intestinal inflammation in children with autism spectrum disorders in response to maternal gut bacteria.
Tue Jan 11 00:00:00 EST 2022
Network Pharmacology Analysis and Experimental Validation to Investigate the Mechanism of Total Flavonoids of Rhizoma Drynariae in Treating Rheumatoid Arthritis.
Drug design, development and therapy
Chen GY,Luo J,Liu Y,Yu XB,Liu XY,Tao QW
25-7177-82 was used in Western Blot to indicate that the treatment of RA with TFRD is closely related to inhibiting Th17 differentiation and inflammatory response of synoviocytes.
Thu Jun 16 00:00:00 EDT 2022
Human gut bacterial metabolism drives Th17 activation and colitis.
Cell host & microbe
Alexander M,Ang QY,Nayak RR,Bustion AE,Sandy M,Zhang B,Upadhyay V,Pollard KS,Lynch SV,Turnbaugh PJ
25-7177-82 was used in Flow cytometry/Cell sorting to support a role for human gut bacterial metabolism in driving Th17-dependent autoimmunity.
Wed Jan 12 00:00:00 EST 2022
Dysbiosis exacerbates colitis by promoting ubiquitination and accumulation of the innate immune adaptor STING in myeloid cells.
Immunity
Shmuel-Galia L,Humphries F,Lei X,Ceglia S,Wilson R,Jiang Z,Ketelut-Carneiro N,Foley SE,Pechhold S,Houghton J,Muneeruddin K,Shaffer SA,McCormick BA,Reboldi A,Ward D,Marshak-Rothstein A,Fitzgerald KA
25-7177-82 was used in Flow cytometry/Cell sorting to suggest a positive feedback loop wherein dysbiosis foments the accumulation of STING in intestinal myeloid cells, driving intestinal inflammation.
Tue Jun 08 00:00:00 EDT 2021
Trichinella spiralis Paramyosin Induces Colonic Regulatory T Cells to Mitigate Inflammatory Bowel Disease.
Frontiers in cell and developmental biology
Hao C,Wang W,Zhan B,Wang Z,Huang J,Sun X,Zhu X
Published figure using IL-17A monoclonal antibody (Product # 25-7177-82) in Flow Cytometry
Tue Aug 03 00:00:00 EDT 2021
Prevention of EAE by tolerogenic vaccination with PEGylated antigenic peptides.
Therapeutic advances in chronic disease
Pfeil J,Simonetti M,Lauer U,von Thülen B,Durek P,Poulsen C,Pawlowska J,Kröger M,Krähmer R,Leenders F,Hoffmann U,Hamann A
Published figure using IL-17A monoclonal antibody (Product # 25-7177-82) in Flow Cytometry
Tue Nov 07 00:00:00 EST 2023
Preliminary analysis of immunoregulatory mechanism of hyperhomocysteinemia-induced brain injury in Wistar-Kyoto rats.
Experimental and therapeutic medicine
Zhang Y,Wang L,Li X,Geng J
Published figure using IL-17A monoclonal antibody (Product # 25-7177-82) in Flow Cytometry
Sat May 01 00:00:00 EDT 2021
Preliminary analysis of immunoregulatory mechanism of hyperhomocysteinemia-induced brain injury in Wistar-Kyoto rats.
Experimental and therapeutic medicine
Zhang Y,Wang L,Li X,Geng J
Published figure using IL-17A monoclonal antibody (Product # 25-7177-82) in Flow Cytometry
Sat May 01 00:00:00 EDT 2021
In Vivo Induction of Regulatory T Cells Via CTLA-4 Signaling Peptide to Control Autoimmune Encephalomyelitis and Prevent Disease Relapse.
Advanced science (Weinheim, Baden-Wurttemberg, Germany)
Kim GR,Kim WJ,Lim S,Lee HG,Koo JH,Nam KH,Kim SM,Park SD,Choi JM
Published figure using IL-17A monoclonal antibody (Product # 25-7177-82) in Flow Cytometry
Thu Jul 01 00:00:00 EDT 2021
G-protein-coupled receptor P2Y10 facilitates chemokine-induced CD4 T cell migration through autocrine/paracrine mediators.
Nature communications
Gurusamy M,Tischner D,Shao J,Klatt S,Zukunft S,Bonnavion R,Günther S,Siebenbrodt K,Kestner RI,Kuhlmann T,Fleming I,Offermanns S,Wettschureck N
Published figure using IL-17A monoclonal antibody (Product # 25-7177-82) in Flow Cytometry
Tue Nov 23 00:00:00 EST 2021
The RNase MCPIP3 promotes skin inflammation by orchestrating myeloid cytokine response.
Nature communications
Liu B,Huang J,Ashraf A,Rahaman O,Lou J,Wang L,Cai P,Wen J,Anwaar S,Liu X,Ni H,Ganguly D,Zhao J,Yang CY
Published figure using IL-17A monoclonal antibody (Product # 25-7177-82) in Flow Cytometry
Fri Jul 02 00:00:00 EDT 2021
Prunella vulgaris L. Attenuates Experimental Autoimmune Thyroiditis by Inhibiting HMGB1/TLR9 Signaling.
Drug design, development and therapy
Guo Q,Qu H,Zhang H,Zhong X
Published figure using IL-17A monoclonal antibody (Product # 25-7177-82) in Flow Cytometry
Tue Feb 22 00:00:00 EST 2022
Epithelial-myeloid exchange of MHC class II constrains immunity and microbiota composition.
Cell reports
Stephens WZ,Kubinak JL,Ghazaryan A,Bauer KM,Bell R,Buhrke K,Chiaro TR,Weis AM,Tang WW,Monts JK,Soto R,Ekiz HA,O'Connell RM,Round JL
25-7177-82 was used in Flow cytometry/Cell sorting to demonstrate a role for IEC-derived MHC class II in constraining microbiota composition and inducing tolerogenic responses against it.
Tue Nov 02 00:00:00 EDT 2021
Analysis of T cells in mouse lymphoid tissue and blood with flow cytometry.
STAR protocols
Skordos I,Demeyer A,Beyaert R
Published figure using IL-17A monoclonal antibody (Product # 25-7177-82) in Flow Cytometry
Fri Mar 19 00:00:00 EDT 2021
Intestinal barrier dysfunction plays an integral role in arthritis pathology and can be targeted to ameliorate disease.
Med (New York, N.Y.)
Matei DE,Menon M,Alber DG,Smith AM,Nedjat-Shokouhi B,Fasano A,Magill L,Duhlin A,Bitoun S,Gleizes A,Hacein-Bey-Abina S,Manson JJ,Rosser EC,Klein N,Blair PA,Mauri C
Published figure using IL-17A monoclonal antibody (Product # 25-7177-82) in Flow Cytometry
Fri Jul 09 00:00:00 EDT 2021
Niche-Selective Inhibition of Pathogenic Th17 Cells by Targeting Metabolic Redundancy.
Cell
Wu L,Hollinshead KER,Hao Y,Au C,Kroehling L,Ng C,Lin WY,Li D,Silva HM,Shin J,Lafaille JJ,Possemato R,Pacold ME,Papagiannakopoulos T,Kimmelman AC,Satija R,Littman DR
25-7177-82 was used in Flow Cytometry to suggest that inhibiting glycolysis by targeting Gpi1 could be an effective therapeutic strategy with minimum toxicity for Th17-mediated autoimmune diseases, and, more generally, that metabolic redundancies can be exploited for selective targeting of disease processes.
Thu Aug 06 00:00:00 EDT 2020
Pharmacological Activation of Pyruvate Kinase M2 Inhibits CD4+ T Cell Pathogenicity and Suppresses Autoimmunity.
Cell metabolism
Angiari S,Runtsch MC,Sutton CE,Palsson-McDermott EM,Kelly B,Rana N,Kane H,Papadopoulou G,Pearce EL,Mills KHG,O'Neill LAJ
Published figure using IL-17A monoclonal antibody (Product # 25-7177-82) in Flow Cytometry
Tue Feb 04 00:00:00 EST 2020
Dermal Adipocyte Lipolysis and Myofibroblast Conversion Are Required for Efficient Skin Repair.
Cell stem cell
Shook BA,Wasko RR,Mano O,Rutenberg-Schoenberg M,Rudolph MC,Zirak B,Rivera-Gonzalez GC,López-Giráldez F,Zarini S,Rezza A,Clark DA,Rendl M,Rosenblum MD,Gerstein MB,Horsley V
25-7177-82 was used in Flow Cytometry to identify an essential role for adipocyte lipolysis in regulating inflammation and repair after injury in skin.
Thu Jun 04 00:00:00 EDT 2020
Bcl6 and Blimp1 reciprocally regulate ST2+ Treg-cell development in the context of allergic airway inflammation.
The Journal of allergy and clinical immunology
Koh B,Ulrich BJ,Nelson AS,Panangipalli G,Kharwadkar R,Wu W,Xie MM,Fu Y,Turner MJ,Paczesny S,Janga SC,Dent AL,Kaplan MH
25-7177 was used in Flow cytometry/Cell sorting to define the functions of Bcl6 in Treg cells, including Tfr cells, in the context of allergic airway inflammation.
Sun Nov 01 00:00:00 EDT 2020
GRIM-19 Ameliorates Multiple Sclerosis in a Mouse Model of Experimental Autoimmune Encephalomyelitis with Reciprocal Regulation of IFNγ/Th1 and IL-17A/Th17 Cells.
Immune network
Moon J,Lee SH,Lee SY,Ryu J,Jhun J,Choi J,Kim GN,Roh S,Park SH,Cho ML
Published figure using IL-17A monoclonal antibody (Product # 25-7177-82) in Flow Cytometry
Thu Oct 01 00:00:00 EDT 2020
IL-17A-producing T cells exacerbate fine particulate matter-induced lung inflammation and fibrosis by inhibiting PI3K/Akt/mTOR-mediated autophagy.
Journal of cellular and molecular medicine
Cong LH,Li T,Wang H,Wu YN,Wang SP,Zhao YY,Zhang GQ,Duan J
Published figure using IL-17A monoclonal antibody (Product # 25-7177-82) in Flow Cytometry
Sat Aug 01 00:00:00 EDT 2020
Exploring the Mechanism on the Medullary Visceral Zone Inhibiting the Cholinergic Anti-inflammatory Pathway Induced by Sepsis.
Mediators of inflammation
Li HB,Zhou Y,Zhao AH,Guo LL
Published figure using IL-17A monoclonal antibody (Product # 25-7177-82) in Flow Cytometry
Mon Aug 02 00:00:00 EDT 2021
FUT1 deficiency elicits immune dysregulation and corneal opacity in steady state and under stress.
Cell death & disease
Kim KW,Ryu JS,Ko JH,Kim JY,Kim HJ,Lee HJ,Oh JH,Chung JH,Oh JY
Published figure using IL-17A monoclonal antibody (Product # 25-7177-82) in Flow Cytometry
Fri Apr 24 00:00:00 EDT 2020
Mitochondrial Pyruvate Carrier 1 Promotes Peripheral T Cell Homeostasis through Metabolic Regulation of Thymic Development.
Cell reports
Ramstead AG,Wallace JA,Lee SH,Bauer KM,Tang WW,Ekiz HA,Lane TE,Cluntun AA,Bettini ML,Round JL,Rutter J,O'Connell RM
Published figure using IL-17A monoclonal antibody (Product # 25-7177-82) in Flow Cytometry
Tue Mar 03 00:00:00 EST 2020
UCP3 reciprocally controls CD4+ Th17 and Treg cell differentiation.
PloS one
O'Connor EB,Muñoz-Wolf N,Leon G,Lavelle EC,Mills KHG,Walsh PT,Porter RK
Published figure using IL-17A monoclonal antibody (Product # 25-7177-82) in Flow Cytometry
Thu Jan 07 00:00:00 EST 2021
M1 Macrophage Derived Exosomes Aggravate Experimental Autoimmune Neuritis via Modulating Th1 Response.
Frontiers in immunology
Du T,Yang CL,Ge MR,Liu Y,Zhang P,Li H,Li XL,Li T,Liu YD,Dou YC,Yang B,Duan RS
Published figure using IL-17A monoclonal antibody (Product # 25-7177-82) in Flow Cytometry
Tue Apr 13 00:00:00 EDT 2021
Lactobacillus reuteri 5454 and Bifidobacterium animalis ssp. lactis 5764 improve colitis while differentially impacting dendritic cells maturation and antimicrobial responses.
Scientific reports
Hrdý J,Alard J,Couturier-Maillard A,Boulard O,Boutillier D,Delacre M,Lapadatescu C,Cesaro A,Blanc P,Pot B,Ryffel B,Chamaillard M,Grangette C
Published figure using IL-17A monoclonal antibody (Product # 25-7177-82) in Flow Cytometry
Tue Mar 24 00:00:00 EDT 2020
Cell-Type-Specific Responses to Interleukin-1 Control Microbial Invasion and Tumor-Elicited Inflammation in Colorectal Cancer.
Immunity
Dmitrieva-Posocco O,Dzutsev A,Posocco DF,Hou V,Yuan W,Thovarai V,Mufazalov IA,Gunzer M,Shilovskiy IP,Khaitov MR,Trinchieri G,Waisman A,Grivennikov SI
25-7177-82 was used in Flow Cytometry to examine the impact of IL-1 signaling, a key regulator of the IL-17 pathway, in different cell types within the CRC microenvironment.
Tue Jan 15 00:00:00 EST 2019
Cell-Type-Specific Responses to Interleukin-1 Control Microbial Invasion and Tumor-Elicited Inflammation in Colorectal Cancer.
Immunity
Dmitrieva-Posocco O,Dzutsev A,Posocco DF,Hou V,Yuan W,Thovarai V,Mufazalov IA,Gunzer M,Shilovskiy IP,Khaitov MR,Trinchieri G,Waisman A,Grivennikov SI
25-7177-82 was used in Flow Cytometry to examine the impact of IL-1 signaling, a key regulator of the IL-17 pathway, in different cell types within the CRC microenvironment.
Tue Jan 15 00:00:00 EST 2019
Expansion of Bacteriophages Is Linked to Aggravated Intestinal Inflammation and Colitis.
Cell host & microbe
Gogokhia L,Buhrke K,Bell R,Hoffman B,Brown DG,Hanke-Gogokhia C,Ajami NJ,Wong MC,Ghazaryan A,Valentine JF,Porter N,Martens E,O'Connell R,Jacob V,Scherl E,Crawford C,Stephens WZ,Casjens SR,Longman RS,Round JL
25-7177 was used in Flow cytometry/Cell sorting to indicate that bacteriophages can alter mucosal immunity to impact mammalian health.
Wed Feb 13 00:00:00 EST 2019
Lactobacillus rhamnosus GG attenuates tenofovir disoproxil fumarate-induced bone loss in male mice via gut-microbiota-dependent anti-inflammation.
Therapeutic advances in chronic disease
Liu H,Gu R,Li W,Zhou W,Cong Z,Xue J,Liu Y,Wei Q,Zhou Y
Published figure using IL-17A monoclonal antibody (Product # 25-7177-82) in Flow Cytometry
Sat Apr 09 00:00:00 EDT 2022
Interleukin 10 Gene-Modified Bone Marrow-Derived Dendritic Cells Attenuate Liver Fibrosis in Mice by Inducing Regulatory T Cells and Inhibiting the TGF-β/Smad Signaling Pathway.
Mediators of inflammation
Xu Y,Tang X,Yang M,Zhang S,Li S,Chen Y,Liu M,Guo Y,Lu M
Published figure using IL-17A monoclonal antibody (Product # 25-7177-82) in Flow Cytometry
Tue Jun 11 00:00:00 EDT 2019
IL-31 plays dual roles in lung inflammation in an OVA-induced murine asthma model.
Biology open
Huang J,Yue H,Jiang T,Gao J,Shi Y,Shi B,Wu X,Gou X
Published figure using IL-17A monoclonal antibody (Product # 25-7177-82) in Flow Cytometry
Tue Jan 15 00:00:00 EST 2019
Interleukin-27 Is Essential for Type 1 Diabetes Development and Sjögren Syndrome-like Inflammation.
Cell reports
Ciecko AE,Foda B,Barr JY,Ramanathan S,Atkinson MA,Serreze DV,Geurts AM,Lieberman SM,Chen YG
25-7177-82 was used in Flow Cytometry to reveal that IL-27 contributes to autoimmunity in NOD mice through multiple mechanisms and provides substantial evidence to support its pathogenic role in human T1D.
Tue Dec 03 00:00:00 EST 2019
Complement Activation via a C3a Receptor Pathway Alters CD4+ T Lymphocytes and Mediates Lung Cancer Progression.
Cancer research
Kwak JW,Laskowski J,Li HY,McSharry MV,Sippel TR,Bullock BL,Johnson AM,Poczobutt JM,Neuwelt AJ,Malkoski SP,Weiser-Evans MC,Lambris JD,Clambey ET,Thurman JM,Nemenoff RA
25-7177 was used in Flow cytometry/Cell sorting to study the mechanism relating complement activation to tumour progression in multiple immunocompetent orthotopic models of lung cancer.
Mon Jan 01 00:00:00 EST 2018
Bryostatin-1 alleviates experimental multiple sclerosis.
Proceedings of the National Academy of Sciences of the United States of America
Kornberg MD,Smith MD,Shirazi HA,Calabresi PA,Snyder SH,Kim PM
Published figure using IL-17A monoclonal antibody (Product # 25-7177-82) in Flow Cytometry
Tue Feb 27 00:00:00 EST 2018
RKIP mediates autoimmune inflammation by positively regulating IL-17R signaling.
EMBO reports
Lin W,Wang N,Zhou K,Su F,Jiang Y,Shou J,Liu H,Ma C,Qian Y,Wang K,Wang X
Published figure using IL-17A monoclonal antibody (Product # 25-7177-82) in Flow Cytometry
Fri Jun 01 00:00:00 EDT 2018
De Novo Fatty Acid Synthesis During Mycobacterial Infection Is a Prerequisite for the Function of Highly Proliferative T Cells, But Not for Dendritic Cells or Macrophages.
Frontiers in immunology
Stüve P,Minarrieta L,Erdmann H,Arnold-Schrauf C,Swallow M,Guderian M,Krull F,Hölscher A,Ghorbani P,Behrends J,Abraham WR,Hölscher C,Sparwasser TD,Berod L
25-7177-82 was used in Flow Cytometry to reveal that acetyl-CoA carboxylase 1-dependent fatty acid synthesis is a crucial mechanism in T cells, but not dendritic cells or macrophages, to fight against mycobacterial infection.
Wed Apr 10 00:00:00 EDT 2019
MicroRNA-126 deficiency enhanced the activation and function of CD4+ T cells by elevating IRS-1 pathway.
Clinical and experimental immunology
Chu F,Hu Y,Zhou Y,Guo M,Lu J,Zheng W,Xu H,Zhao J,Xu L
Published figure using IL-17A monoclonal antibody (Product # 25-7177-82) in Flow Cytometry
Thu Feb 01 00:00:00 EST 2018
Combined treatment with simvastatin and rapamycin attenuates cardiac allograft rejection through the regulation of T helper 17 and regulatory T cells.
Experimental and therapeutic medicine
Liu Y,Sun L,Chen W,Chuai J,Shang Y,Zhang D,Fu B,Tian H,Jiang S
Published figure using IL-17A monoclonal antibody (Product # 25-7177-82) in Flow Cytometry
Thu Feb 01 00:00:00 EST 2018
Baicalin Downregulates RLRs Signaling Pathway to Control Influenza A Virus Infection and Improve the Prognosis.
Evidence-based complementary and alternative medicine : eCAM
Pang P,Zheng K,Wu S,Xu H,Deng L,Shi Y,Chen X
25-7177 was used in Flow cytometry/Cell sorting to investigate the effects of baicalin on controlling the pulmonary infection and improving the prognosis in influenza A virus infection.
Thu Oct 01 00:00:00 EDT 2020
Glutathione de novo synthesis but not recycling process coordinates with glutamine catabolism to control redox homeostasis and directs murine T cell differentiation.
eLife
Lian G,Gnanaprakasam JR,Wang T,Wu R,Chen X,Liu L,Shen Y,Yang M,Yang J,Chen Y,Vasiliou V,Cassel TA,Green DR,Liu Y,Fan TW,Wang R
25-7177 was used in Flow cytometry/Cell sorting to examine the role of glutamine catabolism in fuelling the de novo synthesis of glutathionine, and directing the lineage choice of T cells.
Mon Sep 10 00:00:00 EDT 2018
Vibrio vulnificus RtxA Is a Major Factor Driving Inflammatory T Helper Type 17 Cell Responses in vitro and in vivo.
Frontiers in immunology
Lee A,Kim MS,Cho D,Jang KK,Choi SH,Kim TS
Published figure using IL-17A monoclonal antibody (Product # 25-7177-82) in Flow Cytometry
Mon Sep 30 00:00:00 EDT 2019
ITGB4 deficiency in bronchial epithelial cells directs airway inflammation and bipolar disorder-related behavior.
Journal of neuroinflammation
Han L,Wang L,Tang S,Yuan L,Wu S,Du X,Xiang Y,Qu X,Liu H,Luo H,Qin X,Liu C
Published figure using IL-17A monoclonal antibody (Product # 25-7177-82) in Flow Cytometry
Fri Aug 31 00:00:00 EDT 2018
Epigenetic control of IL-23 expression in keratinocytes is important for chronic skin inflammation.
Nature communications
Li H,Yao Q,Mariscal AG,Wu X,Hülse J,Pedersen E,Helin K,Waisman A,Vinkel C,Thomsen SF,Avgustinova A,Benitah SA,Lovato P,Norsgaard H,Mortensen MS,Veng L,Rozell B,Brakebusch C
Published figure using IL-17A monoclonal antibody (Product # 25-7177-82) in Flow Cytometry
Thu Apr 12 00:00:00 EDT 2018
Trichinella spiralis Infection Mitigates Collagen-Induced Arthritis via Programmed Death 1-Mediated Immunomodulation.
Frontiers in immunology
Cheng Y,Zhu X,Wang X,Zhuang Q,Huyan X,Sun X,Huang J,Zhan B,Zhu X
25-7177 was used in Flow cytometry/Cell sorting to introduce the first evidence that PD-1 plays a critical role in Trichinella spiralis infection-attenuated collagen-induced arthritis in a mouse model by regulating the CD4+ T cell function, which may provide the new insights into the mechanisms of helminth-induced immunomodulation of host autoimmunity.
Mon Jan 28 00:00:00 EST 2019
Maternal gut bacteria promote neurodevelopmental abnormalities in mouse offspring.
Nature
Kim S,Kim H,Yim YS,Ha S,Atarashi K,Tan TG,Longman RS,Honda K,Littman DR,Choi GB,Huh JR
Published figure using IL-17A monoclonal antibody (Product # 25-7177-82) in Flow Cytometry
Thu Sep 28 00:00:00 EDT 2017
Regulatory Innate Lymphoid Cells Control Innate Intestinal Inflammation.
Cell
Wang S,Xia P,Chen Y,Qu Y,Xiong Z,Ye B,Du Y,Tian Y,Yin Z,Xu Z,Fan Z
25-7177 was used in Flow cytometry/Cell sorting to identify a regulatory subpopulation of innate lymphoid cells that exists in the gut, and harbour a unique gene identity.
Thu Sep 21 00:00:00 EDT 2017
Regulatory T Cells in Skin Facilitate Epithelial Stem Cell Differentiation.
Cell
Ali N,Zirak B,Rodriguez RS,Pauli ML,Truong HA,Lai K,Ahn R,Corbin K,Lowe MM,Scharschmidt TC,Taravati K,Tan MR,Ricardo-Gonzalez RR,Nosbaum A,Bertolini M,Liao W,Nestle FO,Paus R,Cotsarelis G,Abbas AK,Rosenblum MD
25-7177 was used in Flow cytometry/Cell sorting to study the role of regulatory T cells in hair follicles and hair follicle stem cell biology.
Thu Jun 01 00:00:00 EDT 2017
Epithelial-Cell-Derived Phospholipase A2 Group 1B Is an Endogenous Anthelmintic.
Cell host & microbe
Entwistle LJ,Pelly VS,Coomes SM,Kannan Y,Perez-Lloret J,Czieso S,Silva Dos Santos M,MacRae JI,Collinson L,Sesay A,Nikolov N,Metidji A,Helmby H,Hui DY,Wilson MS
25-7177 was used in Flow cytometry/Cell sorting to uncover epithelial-cell-derived Pla2g1b as an essential mediator of helminth killing.
Wed Oct 11 00:00:00 EDT 2017
miR-146a modulates autoreactive Th17 cell differentiation and regulates organ-specific autoimmunity.
The Journal of clinical investigation
Li B,Wang X,Choi IY,Wang YC,Liu S,Pham AT,Moon H,Smith DJ,Rao DS,Boldin MP,Yang L
Published figure using IL-17A monoclonal antibody (Product # 25-7177-82) in Flow Cytometry
Mon Oct 02 00:00:00 EDT 2017
Microbial, metabolomic, and immunologic dynamics in a relapsing genetic mouse model of colitis induced by T-synthase deficiency.
Gut microbes
Jacobs JP,Lin L,Goudarzi M,Ruegger P,McGovern DP,Fornace AJ,Borneman J,Xia L,Braun J
Published figure using IL-17A monoclonal antibody (Product # 25-7177-82) in Flow Cytometry
Mon Jan 02 00:00:00 EST 2017
Critical role of caspase-8-mediated IL-1 signaling in promoting Th2 responses during asthma pathogenesis.
Mucosal immunology
Qi X,Gurung P,Malireddi RK,Karmaus PW,Sharma D,Vogel P,Chi H,Green DR,Kanneganti TD
Published figure using IL-17A monoclonal antibody (Product # 25-7177-82) in Flow Cytometry
Sun Jan 01 00:00:00 EST 2017
CD4+ Th2 cells are directly regulated by IL-10 during allergic airway inflammation.
Mucosal immunology
Coomes SM,Kannan Y,Pelly VS,Entwistle LJ,Guidi R,Perez-Lloret J,Nikolov N,Müller W,Wilson MS
Sun Jan 01 00:00:00 EST 2017
PRMT5-Selective Inhibitors Suppress Inflammatory T Cell Responses and Experimental Autoimmune Encephalomyelitis.
Journal of immunology (Baltimore, Md. : 1950)
Webb LM,Amici SA,Jablonski KA,Savardekar H,Panfil AR,Li L,Zhou W,Peine K,Karkhanis V,Bachelder EM,Ainslie KM,Green PL,Li C,Baiocchi RA,Guerau-de-Arellano M
Published figure using IL-17A monoclonal antibody (Product # 25-7177-82) in Flow Cytometry
Wed Feb 15 00:00:00 EST 2017
Placenta‑derived mesenchymal stem cells improve airway hyperresponsiveness and inflammation in asthmatic rats by modulating the Th17/Treg balance.
Molecular medicine reports
Li Y,Li H,Cao Y,Wu F,Ma W,Wang Y,Sun S
Published figure using IL-17A monoclonal antibody (Product # 25-7177-82) in Flow Cytometry
Fri Dec 01 00:00:00 EST 2017
Upregulation of SOCS3 in lung CD4+ T cells in a mouse model of chronic PA lung infection and suppression of Th17‑mediated neutrophil recruitment in exogenous SOCS3 transfer in vitro.
Molecular medicine reports
Ding FM,Liao RM,Chen YQ,Xie GG,Zhang PY,Shao P,Zhang M
Published figure using IL-17A monoclonal antibody (Product # 25-7177-82) in Flow Cytometry
Sat Jul 01 00:00:00 EDT 2017
Batf3-dependent CD8α+ Dendritic Cells Aggravates Atherosclerosis via Th1 Cell Induction and Enhanced CCL5 Expression in Plaque Macrophages.
EBioMedicine
Li Y,Liu X,Duan W,Tian H,Zhu G,He H,Yao S,Yi S,Song W,Tang H
Published figure using IL-17A monoclonal antibody (Product # 25-7177-82) in Flow Cytometry
Sat Apr 01 00:00:00 EDT 2017
Paeoniflorin Ameliorates Experimental Autoimmune Encephalomyelitis via Inhibition of Dendritic Cell Function and Th17 Cell Differentiation.
Scientific reports
Zhang H,Qi Y,Yuan Y,Cai L,Xu H,Zhang L,Su B,Nie H
Published figure using IL-17A monoclonal antibody (Product # 25-7177-82) in Flow Cytometry
Mon Feb 06 00:00:00 EST 2017
Essential role for CCR6 in certain inflammatory diseases demonstrated using specific antagonist and knockin mice.
JCI insight
Robert R,Ang C,Sun G,Juglair L,Lim EX,Mason LJ,Payne NL,Bernard CC,Mackay CR
25-7177 was used in Flow cytometry/Cell sorting to investigate the role of CCR6 in the recruitment of T cells to inflammatory sites.
Thu Aug 03 00:00:00 EDT 2017
Traditional Herbal Medicine-Derived Sulforaphene LFS-01 Reverses Colitis in Mice by Selectively Altering the Gut Microbiota and Promoting Intestinal Gamma-Delta T Cells.
Frontiers in pharmacology
Li M,Gao J,Tang Y,Liu M,Wu S,Qu K,Long X,Li H,Liu M,Liu Y,Yuan J,Mao L,Liu Y,Zheng X,Wang E,Wang J,Yang Y
Published figure using IL-17A monoclonal antibody (Product # 25-7177-82) in Flow Cytometry
Wed Sep 30 00:00:00 EDT 2020
Single-cell profiling reveals GPCR heterogeneity and functional patterning during neuroinflammation.
JCI insight
Tischner D,Grimm M,Kaur H,Staudenraus D,Carvalho J,Looso M,Günther S,Wanke F,Moos S,Siller N,Breuer J,Schwab N,Zipp F,Waisman A,Kurschus FC,Offermanns S,Wettschureck N
Published figure using IL-17A monoclonal antibody (Product # 25-7177-82) in Flow Cytometry
Thu Aug 03 00:00:00 EDT 2017
Extrafollicular CD4+ T-B interactions are sufficient for inducing autoimmune-like chronic graft-versus-host disease.
Nature communications
Deng R,Hurtz C,Song Q,Yue C,Xiao G,Yu H,Wu X,Muschen M,Forman S,Martin PJ,Zeng D
Published figure using IL-17A monoclonal antibody (Product # 25-7177-82) in Flow Cytometry
Tue Oct 17 00:00:00 EDT 2017
A tightly regulated IL-22 response maintains immune functions and homeostasis in systemic viral infection.
Scientific reports
Yi P,Liang Y,Yuan DMK,Jie Z,Kwota Z,Chen Y,Cong Y,Fan X,Sun J
Tue Jun 20 00:00:00 EDT 2017
Host-Protozoan Interactions Protect from Mucosal Infections through Activation of the Inflammasome.
Cell
Chudnovskiy A,Mortha A,Kana V,Kennard A,Ramirez JD,Rahman A,Remark R,Mogno I,Ng R,Gnjatic S,Amir ED,Solovyov A,Greenbaum B,Clemente J,Faith J,Belkaid Y,Grigg ME,Merad M
Published figure using IL-17A monoclonal antibody (Product # 25-7177-82) in Flow Cytometry
Thu Oct 06 00:00:00 EDT 2016
Oxygen Sensing by T Cells Establishes an Immunologically Tolerant Metastatic Niche.
Cell
Clever D,Roychoudhuri R,Constantinides MG,Askenase MH,Sukumar M,Klebanoff CA,Eil RL,Hickman HD,Yu Z,Pan JH,Palmer DC,Phan AT,Goulding J,Gattinoni L,Goldrath AW,Belkaid Y,Restifo NP
25-7177 was used in Flow cytometry/Cell sorting to find that T-cell-intrinsic expression of the oxygen-sensing prolyl-hydroxylase proteins is required to maintain local tolerance against innocuous antigens in the lung but powerfully licenses colonization by circulating tumor cells.
Thu Aug 25 00:00:00 EDT 2016
Oligodendrocyte death results in immune-mediated CNS demyelination.
Nature neuroscience
Traka M,Podojil JR,McCarthy DP,Miller SD,Popko B
Published figure using IL-17A monoclonal antibody (Product # 25-7177-82) in Flow Cytometry
Fri Jan 01 00:00:00 EST 2016
Nuclear receptor expression atlas in BMDCs: Nr4a2 restricts immunogenicity of BMDCs and impedes EAE.
European journal of immunology
Saini A,Mahajan S,Gupta P
Published figure using IL-17A monoclonal antibody (Product # 25-7177-82) in Flow Cytometry
Mon Aug 01 00:00:00 EDT 2016
p(⁷⁰S⁶K¹) in the TORC1 pathway is essential for the differentiation of Th17 Cells, but not Th1, Th2, or Treg cells in mice.
European journal of immunology
Sasaki CY,Chen G,Munk R,Eitan E,Martindale J,Longo DL,Ghosh P
Published figure using IL-17A monoclonal antibody (Product # 25-7177-82) in Flow Cytometry
Fri Jan 01 00:00:00 EST 2016
Developmental Progression and Interrelationship of Central and Effector Regulatory T Cell Subsets.
Journal of immunology (Baltimore, Md. : 1950)
Toomer KH,Yuan X,Yang J,Dee MJ,Yu A,Malek TR
25-7177 was used in Flow cytometry/Cell sorting to elucidate the developmental progression and interrelationship of central and effector regulatory T cell subsets.
Sun May 01 00:00:00 EDT 2016
Rapamycin ameliorates CCl4-induced liver fibrosis in mice through reciprocal regulation of the Th17/Treg cell balance.
Molecular medicine reports
Gu L,Deng WS,Sun XF,Zhou H,Xu Q
Published figure using IL-17A monoclonal antibody (Product # 25-7177-82) in Flow Cytometry
Mon Aug 01 00:00:00 EDT 2016
Age-dependent divergent effects of OX40L treatment on the development of diabetes in NOD mice.
Autoimmunity
Haddad CS,Bhattacharya P,Alharshawi K,Marinelarena A,Kumar P,El-Sayed O,Elshabrawy HA,Epstein AL,Prabhakar BS
Published figure using IL-17A monoclonal antibody (Product # 25-7177-82) in Flow Cytometry
Mon Aug 01 00:00:00 EDT 2016
Tropomyosin Receptor Kinase C Targeted Delivery of a Peptidomimetic Ligand-Photosensitizer Conjugate Induces Antitumor Immune Responses Following Photodynamic Therapy.
Scientific reports
Kue CS,Kamkaew A,Voon SH,Kiew LV,Chung LY,Burgess K,Lee HB
Published figure using IL-17A monoclonal antibody (Product # 25-7177-82) in Flow Cytometry
Thu Nov 17 00:00:00 EST 2016
Tamm-Horsfall Protein Regulates Granulopoiesis and Systemic Neutrophil Homeostasis.
Journal of the American Society of Nephrology : JASN
Micanovic R,Chitteti BR,Dagher PC,Srour EF,Khan S,Hato T,Lyle A,Tong Y,Wu XR,El-Achkar TM
Published figure using IL-17A monoclonal antibody (Product # 25-7177-82) in Flow Cytometry
Tue Sep 01 00:00:00 EDT 2015
MHC-mismatched mixed chimerism augments thymic regulatory T-cell production and prevents relapse of EAE in mice.
Proceedings of the National Academy of Sciences of the United States of America
Wu L,Li N,Zhang M,Xue SL,Cassady K,Lin Q,Riggs AD,Zeng D
Published figure using IL-17A monoclonal antibody (Product # 25-7177-82) in Flow Cytometry
Tue Dec 29 00:00:00 EST 2015
Unexpected Role for Adaptive αβTh17 Cells in Acute Respiratory Distress Syndrome.
Journal of immunology (Baltimore, Md. : 1950)
Li JT,Melton AC,Su G,Hamm DE,LaFemina M,Howard J,Fang X,Bhat S,Huynh KM,O'Kane CM,Ingram RJ,Muir RR,McAuley DF,Matthay MA,Sheppard D
Published figure using IL-17A monoclonal antibody (Product # 25-7177-82) in Flow Cytometry
Wed Jul 01 00:00:00 EDT 2015
Interleukin-25 Mediates Transcriptional Control of PD-L1 via STAT3 in Multipotent Human Mesenchymal Stromal Cells (hMSCs) to Suppress Th17 Responses.
Stem cell reports
Wang WB,Yen ML,Liu KJ,Hsu PJ,Lin MH,Chen PM,Sudhir PR,Chen CH,Chen CH,Sytwu HK,Yen BL
Published figure using IL-17A monoclonal antibody (Product # 25-7177-82) in Flow Cytometry
Tue Sep 08 00:00:00 EDT 2015
A Multiple Antigenic Peptide Mimicking Peptidoglycan Induced T Cell Responses to Protect Mice from Systemic Infection with Staphylococcus aureus.
PloS one
Wang XY,Huang ZX,Chen YG,Lu X,Zhu P,Wen K,Fu N,Liu BY
Published figure using IL-17A monoclonal antibody (Product # 25-7177-82) in Flow Cytometry
Tue May 24 00:00:00 EDT 2016
Upregulation of Programmed Death-1 and Its Ligand in Cardiac Injury Models: Interaction with GADD153.
PloS one
Baban B,Liu JY,Qin X,Weintraub NL,Mozaffari MS
Published figure using IL-17A monoclonal antibody (Product # 25-7177-82) in Flow Cytometry
Tue Apr 12 00:00:00 EDT 2016
Chronic hydroxychloroquine improves endothelial dysfunction and protects kidney in a mouse model of systemic lupus erythematosus.
Hypertension (Dallas, Tex. : 1979)
Gómez-Guzmán M,Jiménez R,Romero M,Sánchez M,Zarzuelo MJ,Gómez-Morales M,O'Valle F,López-Farré AJ,Algieri F,Gálvez J,Pérez-Vizcaino F,Sabio JM,Duarte J
25-7177 was used in Flow cytometry/Cell sorting to investigate the effects of hydroxychloroquine on hypertension, endothelial dysfunction, and renal injury in a mouse model of systemic lupus erythematosus.
Fri Aug 01 00:00:00 EDT 2014
mTOR signaling inhibition modulates macrophage/microglia-mediated neuroinflammation and secondary injury via regulatory T cells after focal ischemia.
Journal of immunology (Baltimore, Md. : 1950)
Xie L,Sun F,Wang J,Mao X,Xie L,Yang SH,Su DM,Simpkins JW,Greenberg DA,Jin K
25-7177 was used in Flow cytometry/Cell sorting to investigate the role of mTOR signalling in poststroke neuroinflammation, showing that inhibition modulates neuroinflammation and secondary injury via regulatory T cells.
Sun Jun 15 00:00:00 EDT 2014
Macrophage PTEN regulates expression and secretion of arginase I modulating innate and adaptive immune responses.
Journal of immunology (Baltimore, Md. : 1950)
Sahin E,Haubenwallner S,Kuttke M,Kollmann I,Halfmann A,Dohnal AM,Chen L,Cheng P,Hoesel B,Einwallner E,Brunner J,Kral JB,Schrottmaier WC,Thell K,Saferding V,Blüml S,Schabbauer G
25-7177 was used in Flow cytometry/Cell sorting to study the role of extracellular Arginase I in inflammation and immunity.
Fri Aug 15 00:00:00 EDT 2014
A chitin-like component on sclerotic cells of Fonsecaea pedrosoi inhibits Dectin-1-mediated murine Th17 development by masking β-glucans.
PloS one
Dong B,Li D,Li R,Chen SC,Liu W,Liu W,Chen L,Chen Y,Zhang X,Tong Z,Xia Y,Xia P,Wang Y,Duan Y
Published figure using IL-17A monoclonal antibody (Product # 25-7177-82) in Flow Cytometry
Mon Sep 28 00:00:00 EDT 2015
MHC class II-dependent B cell APC function is required for induction of CNS autoimmunity independent of myelin-specific antibodies.
The Journal of experimental medicine
Molnarfi N,Schulze-Topphoff U,Weber MS,Patarroyo JC,Prod'homme T,Varrin-Doyer M,Shetty A,Linington C,Slavin AJ,Hidalgo J,Jenne DE,Wekerle H,Sobel RA,Bernard CC,Shlomchik MJ,Zamvil SS
25-7177 was used in Flow cytometry/Cell sorting to investigate the contribution of B cells to antigen presentation and pathogenic T cell activation in the multiple sclerosis model experimental autoimmune encephalomyelitis.
Mon Dec 16 00:00:00 EST 2013
Double deficiency in IL-17 and IFN-γ signalling significantly suppresses the development of diabetes in the NOD mouse.
Diabetologia
Kuriya G,Uchida T,Akazawa S,Kobayashi M,Nakamura K,Satoh T,Horie I,Kawasaki E,Yamasaki H,Yu L,Iwakura Y,Sasaki H,Nagayama Y,Kawakami A,Abiru N
25-7177 was used in Flow cytometry/Cell sorting to study the suppression of diabetes in NOD mice due to IL-17 and IFN-γ deficiency.
Thu Aug 01 00:00:00 EDT 2013
R-phycoerythrin-conjugated antibodies are inappropriate for intracellular staining of murine plasma cells.
Cytometry. Part A : the journal of the International Society for Analytical Cytology
Kim MS,Kim TS
Published figure using IL-17A monoclonal antibody (Product # 25-7177-82) in Flow Cytometry
Wed May 01 00:00:00 EDT 2013
Interleukin-22 as a molecular adjuvant facilitates IL-17-producing CD8+ T cell responses against a HBV DNA vaccine in mice.
Human vaccines & immunotherapeutics
Wu B,Zou Q,Hu Y,Wang B
Published figure using IL-17A monoclonal antibody (Product # 25-7177-82) in Flow Cytometry
Tue Oct 01 00:00:00 EDT 2013
Soluble MOG35-55/I-A(b) dimers ameliorate experimental autoimmune encephalomyelitis by reducing encephalitogenic T cells.
PloS one
Gong Y,Wang Z,Liang Z,Duan H,Ouyang L,Yu Q,Xu Z,Shen G,Weng X,Wu X
Published figure using IL-17A monoclonal antibody (Product # 25-7177-82) in Flow Cytometry
Fri Jul 19 00:00:00 EDT 2013
Eosinophils contribute to IL-4 production and shape the T-helper cytokine profile and inflammatory response in pulmonary cryptococcosis.
The American journal of pathology
Piehler D,Stenzel W,Grahnert A,Held J,Richter L,Köhler G,Richter T,Eschke M,Alber G,Müller U
25-7177 was used in Flow cytometry/Cell sorting to investigate the time course of IL-4 production and its innate cellular source in mice infected intranasally with Cryptococcus neoformans.
Mon Aug 01 00:00:00 EDT 2011
Anti-IL-23 antibody blockade of IL-23/IL-17 pathway attenuates airway obliteration in rat orthotopic tracheal transplantation.
International immunopharmacology
Cao H,Lan Q,Shi Q,Zhou X,Liu G,Liu J,Tang G,Qiu C,Qiu C,Xu J,Fan H,Liu Z
Sun May 01 00:00:00 EDT 2011
T cells from Programmed Death-1 deficient mice respond poorly to Mycobacterium tuberculosis infection.
PloS one
Tousif S,Singh Y,Prasad DV,Sharma P,Van Kaer L,Das G
Thu May 12 00:00:00 EDT 2011
Role of epithelial integrin-linked kinase in promoting intestinal inflammation: effects on CCL2, fibronectin and the T cell repertoire.
BMC immunology
Assi K,Patterson S,Dedhar S,Owen D,Levings M,Salh B
Mon Aug 01 00:00:00 EDT 2011
IDO activates regulatory T cells and blocks their conversion into Th17-like T cells.
Journal of immunology (Baltimore, Md. : 1950)
Baban B,Chandler PR,Sharma MD,Pihkala J,Koni PA,Munn DH,Mellor AL
Published figure using IL-17A monoclonal antibody (Product # 25-7177-82) in Flow Cytometry
Sat Aug 15 00:00:00 EDT 2009
Early life exposure to lipopolysaccharide suppresses experimental autoimmune encephalomyelitis by promoting tolerogenic dendritic cells and regulatory T cells.
Journal of immunology (Baltimore, Md. : 1950)
Ellestad KK,Tsutsui S,Noorbakhsh F,Warren KG,Yong VW,Pittman QJ,Power C
Wed Jul 01 00:00:00 EDT 2009
