Positive Control: Raji
Predicted Reactivity: Mouse (95%), Bovine (98%)
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
DNA-binding protein that binds to the 5'GGGAATRCC-3' Ikaros-binding sequence. Transcriptional repressor. Interacts with SPI1 and MITF to repress transcription of the CTSK and ACP5 promoters via recruitment of corepressors SIN3A and CTBP2. May be involved in the development of central and peripheral nervous systems.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: IKAROS family zinc finger 4 (Eos); Ikaros family zinc finger protein 4; Zinc finger protein Eos; zinc finger protein, subfamily 1A, 4 (Eos); zinc finger transcription factor Eos
Gene Aliases: EOS; IKZF4; KIAA1782; ZNFN1A4
UniProt ID: (Human) Q9H2S9
Entrez Gene ID: (Human) 64375
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