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Product Details
PA5-30054
Species Reactivity
Host/Isotype
Class
Type
Immunogen
Conjugate
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Purification
Storage buffer
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RRID
Product Specific Information
Recommended positive controls: A549, HeLa, HepG2, HCT116.
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
Cytolytic T lymphocytes (CTL) and natural killer (NK) cells share the remarkable ability to recognize, bind, and lyse specific target cells. They are thought to protect their host by lysing cells bearing on their surface 'nonself' antigens, usually peptides or proteins resulting from infection by intracellular pathogens. The protein described here is a T cell- and natural killer cell-specific serine protease that may function as a common component necessary for lysis of target cells by cytotoxic T lymphocytes and natural killer cells.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Bioinformatics
Protein Aliases: CTL tryptase; Cytotoxic T-lymphocyte proteinase 1; Cytotoxic T-lymphocyte-associated serine esterase-3; Fragmentin-1; granzyme 1; Granzyme A; Granzyme A (Cytotoxic T-lymphocyte-associated serine esterase-3; Hanukah factor serine protease); granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3); Granzyme-1; H factor; Hanukah factor serine protease); Hanukkah factor; HF
Gene Aliases: CTLA3; GZMA; HFSP
UniProt ID: (Human) P12544
Entrez Gene ID: (Human) 3001
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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