Product References
The potential role of the pseudobranch of molly fish (Poecilia sphenops) in immunity and cell regeneration.
Scientific reports
Mokhtar DM,Sayed RKA,Zaccone G,Alesci A,Hussein MM
Published figure using GFAP polyclonal antibody (Product # PA5-16291) in Immunohistochemistry (Paraffin)
Mon May 29 00:00:00 EDT 2023
N-homocysteinylation of α-synuclein promotes its aggregation and neurotoxicity.
Aging cell
Zhou L,Guo T,Meng L,Zhang X,Tian Y,Dai L,Niu X,Li Y,Liu C,Chen G,Liu C,Ke W,Zhang Z,Bao A,Zhang Z
PA5-16291 was used in Immunohistochemistry to suggest that the covalent modification of α-synuclein by HTL promotes its aggregation.
Wed Mar 01 00:00:00 EST 2023
Loss of flrt2 gene leads to microphthalmia in zebrafish.
Biology open
Yang S,Huang L,Liang H,Guo J,Liu L,Chen S,Cao M
PA5-16291 was used in Immunohistochemistry to detect the high expression of flrt2 in zebrafish retina.
Thu Jun 15 00:00:00 EDT 2023
Wide-field calcium imaging reveals widespread changes in cortical functional connectivity following mild traumatic brain injury in the mouse.
Neurobiology of disease
Cramer SW,Haley SP,Popa LS,Carter RE,Scott E,Flaherty EB,Dominguez J,Aronson JD,Sabal L,Surinach D,Chen CC,Kodandaramaiah SB,Ebner TJ
PA5-16291 was used in Immunohistochemistry to show that mTBI induces a transient neuroinflammation, without alterations in cognitive or motor behavior, and a reorganized cortical network evidenced by the widespread, chronic alterations in cortical FC.
Sun Jan 01 00:00:00 EST 2023
Ependymal and Neural Stem Cells of Adult Molly Fish (Poecilia sphenops, Valenciennes, 1846) Brain: Histomorphometry, Immunohistochemical, and Ultrastructural Studies.
Cells
Mokhtar DM,Sayed RKA,Zaccone G,Albano M,Hussein MT
PA5-16291 was used in Immunohistochemistry to indicate the role of ECs in neurogenesis.
Sat Aug 27 00:00:00 EDT 2022
Ependymal and Neural Stem Cells of Adult Molly Fish (Poecilia sphenops, Valenciennes, 1846) Brain: Histomorphometry, Immunohistochemical, and Ultrastructural Studies.
Cells
Mokhtar DM,Sayed RKA,Zaccone G,Albano M,Hussein MT
PA5-16291 was used in Immunohistochemistry to indicate the role of ECs in neurogenesis.
Sat Aug 27 00:00:00 EDT 2022
Analysis of the Biomarkers for Neurodegenerative Diseases in Aged Progranulin Deficient Mice.
International journal of molecular sciences
Zhao X,Hasan S,Liou B,Lin Y,Sun Y,Liu C
Published figure using GFAP polyclonal antibody (Product # PA5-16291) in Immunohistochemistry
Thu Jan 06 00:00:00 EST 2022
Multichannel optogenetics combined with laminar recordings for ultra-controlled neuronal interrogation.
Nature communications
Eriksson D,Schneider A,Thirumalai A,Alyahyay M,de la Crompe B,Sharma K,Ruther P,Diester I
PA5-16291 was used in Immunohistochemistry to demonstrate that our framework allows to conduct simultaneous laminar recordings and multifiber stimulations, 3D optogenetic stimulation, connectivity inference, and behavioral quantification in freely moving animals.
Mon Feb 21 00:00:00 EST 2022
Multichannel optogenetics combined with laminar recordings for ultra-controlled neuronal interrogation.
Nature communications
Eriksson D,Schneider A,Thirumalai A,Alyahyay M,de la Crompe B,Sharma K,Ruther P,Diester I
PA5-16291 was used in Immunohistochemistry to demonstrate that our framework allows to conduct simultaneous laminar recordings and multifiber stimulations, 3D optogenetic stimulation, connectivity inference, and behavioral quantification in freely moving animals.
Mon Feb 21 00:00:00 EST 2022
Chlamydia pneumoniae can infect the central nervous system via the olfactory and trigeminal nerves and contributes to Alzheimer's disease risk.
Scientific reports
Chacko A,Delbaz A,Walkden H,Basu S,Armitage CW,Eindorf T,Trim LK,Miller E,West NP,St John JA,Beagley KW,Ekberg JAK
PA5-16291 was used in Immunocytochemistry to show that the nerves extending between the nasal cavity and the brain constitute invasion paths by which Chlamydia pneumoniae can rapidly invade the CNS likely by surviving in glia and leading to Aβ deposition.
Thu Feb 17 00:00:00 EST 2022
Neonatal GALT gene replacement offers metabolic and phenotypic correction through early adulthood in a rat model of classic galactosemia.
Journal of inherited metabolic disease
Daenzer JMI,Rasmussen SA,Patel S,McKenna J,Fridovich-Keil JL
PA5-16291 was used in Immunohistochemistry-immunofluorescence to find that UDP glucose pyrophosphorylase (UGP), which offers a metabolic bypass around missing GALT, was 3-fold more active in brain samples from adult rats than from young pups, offering a possible explanation for the improved ability of older GALT-null rats to metabolize galactose.
Tue Mar 01 00:00:00 EST 2022
An atlas of endogenous DNA double-strand breaks arising during human neural cell fate determination.
Scientific data
Ballarino R,Bouwman BAM,Agostini F,Harbers L,Diekmann C,Wernersson E,Bienko M,Crosetto N
PA5-16291 was used in Immunocytochemistry-immunoflourescence to represent a unique resource that can be harnessed to investigate the role of genome fragility in the pathogenesis of neurodevelopmental disorders.
Tue Jul 12 00:00:00 EDT 2022
Mouse Adapted SARS-CoV-2 (MA10) Viral Infection Induces Neuroinflammation in Standard Laboratory Mice.
Viruses
Amruta N,Ismael S,Leist SR,Gressett TE,Srivastava A,Dinnon KH,Engler-Chiurazzi EB,Maness NJ,Qin X,Kolls JK,Baric RS,Bix G
PA5-16291 was used in Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot to demonstrate that SARS-CoV-2 (MA10) infection induces neuroinflammation in laboratory mice and could be used as a novel model to study SARS-CoV-2-mediated cerebrovascular pathology.
Fri Dec 30 00:00:00 EST 2022
The RNA-Binding Protein HuR Is Integral to the Function of Nociceptors in Mice and Humans.
The Journal of neuroscience : the official journal of the Society for Neuroscience
Kunder N,de la Peña JB,Lou TF,Chase R,Suresh P,Lawson J,Shukla T,Black B,Campbell ZT
PA5-16291 was used in Immunohistochemistry to report an important mechanism of mRNA control in sensory neurons that ensures appropriate nociceptive responses to inflammatory mediators.
Wed Dec 07 00:00:00 EST 2022
VPS35 D620N knockin mice recapitulate cardinal features of Parkinson's disease.
Aging cell
Niu M,Zhao F,Bondelid K,Siedlak SL,Torres S,Fujioka H,Wang W,Liu J,Zhu X
Published figure using GFAP polyclonal antibody (Product # PA5-16291) in Immunohistochemistry
Sat May 01 00:00:00 EDT 2021
VPS35 D620N knockin mice recapitulate cardinal features of Parkinson's disease.
Aging cell
Niu M,Zhao F,Bondelid K,Siedlak SL,Torres S,Fujioka H,Wang W,Liu J,Zhu X
Published figure using GFAP polyclonal antibody (Product # PA5-16291) in Immunohistochemistry
Sat May 01 00:00:00 EDT 2021
VPS35 D620N knockin mice recapitulate cardinal features of Parkinson's disease.
Aging cell
Niu M,Zhao F,Bondelid K,Siedlak SL,Torres S,Fujioka H,Wang W,Liu J,Zhu X
Published figure using GFAP polyclonal antibody (Product # PA5-16291) in Immunohistochemistry
Sat May 01 00:00:00 EDT 2021
Extracellular Vesicles From 3xTg-AD Mouse and Alzheimer's Disease Patient Astrocytes Impair Neuroglial and Vascular Components.
Frontiers in aging neuroscience
González-Molina LA,Villar-Vesga J,Henao-Restrepo J,Villegas A,Lopera F,Cardona-Gómez GP,Posada-Duque R
PA5-16291 was used in Immunocytochemistry to evaluate the effects of adult PS1-KI and 3xTg-AD astrocyte conditioned media (CM) and EVs on NVU components (neuroglia and endothelium) in vitro.
Wed Mar 10 00:00:00 EST 2021
Extracellular Vesicles From 3xTg-AD Mouse and Alzheimer's Disease Patient Astrocytes Impair Neuroglial and Vascular Components.
Frontiers in aging neuroscience
González-Molina LA,Villar-Vesga J,Henao-Restrepo J,Villegas A,Lopera F,Cardona-Gómez GP,Posada-Duque R
PA5-16291 was used in Immunocytochemistry to evaluate the effects of adult PS1-KI and 3xTg-AD astrocyte conditioned media (CM) and EVs on NVU components (neuroglia and endothelium) in vitro.
Wed Mar 10 00:00:00 EST 2021
Mfn2 Overexpression Attenuates MPTP Neurotoxicity In Vivo.
International journal of molecular sciences
Zhao F,Austria Q,Wang W,Zhu X
Published figure using GFAP polyclonal antibody (Product # PA5-16291) in Immunohistochemistry
Sat Jan 09 00:00:00 EST 2021
METTL3-dependent RNA m6A dysregulation contributes to neurodegeneration in Alzheimer's disease through aberrant cell cycle events.
Molecular neurodegeneration
Zhao F,Xu Y,Gao S,Qin L,Austria Q,Siedlak SL,Pajdzik K,Dai Q,He C,Wang W,O'Donnell JM,Tang B,Zhu X
Published figure using GFAP polyclonal antibody (Product # PA5-16291) in Immunocytochemistry
Thu Sep 30 00:00:00 EDT 2021
METTL3-dependent RNA m6A dysregulation contributes to neurodegeneration in Alzheimer's disease through aberrant cell cycle events.
Molecular neurodegeneration
Zhao F,Xu Y,Gao S,Qin L,Austria Q,Siedlak SL,Pajdzik K,Dai Q,He C,Wang W,O'Donnell JM,Tang B,Zhu X
Published figure using GFAP polyclonal antibody (Product # PA5-16291) in Immunocytochemistry
Thu Sep 30 00:00:00 EDT 2021
Mesenchymal stem cell-derived extracellular vesicles ameliorate Alzheimer's disease-like phenotypes in a preclinical mouse model.
Theranostics
Cone AS,Yuan X,Sun L,Duke LC,Vreones MP,Carrier AN,Kenyon SM,Carver SR,Benthem SD,Stimmell AC,Moseley SC,Hike D,Grant SC,Wilber AA,Olcese JM,Meckes DG
PA5-16291 was used in Immunohistochemistry (PFA fixed), Western Blot to test the potential therapeutic effects of mesenchymal stem cell extracellular vesicles.
Wed Jan 19 00:00:00 EST 2022
Mesenchymal stem cell-derived extracellular vesicles ameliorate Alzheimer's disease-like phenotypes in a preclinical mouse model.
Theranostics
Cone AS,Yuan X,Sun L,Duke LC,Vreones MP,Carrier AN,Kenyon SM,Carver SR,Benthem SD,Stimmell AC,Moseley SC,Hike D,Grant SC,Wilber AA,Olcese JM,Meckes DG
PA5-16291 was used in Immunohistochemistry (PFA fixed), Western Blot to test the potential therapeutic effects of mesenchymal stem cell extracellular vesicles.
Wed Jan 19 00:00:00 EST 2022
Recombinant Adiponectin Peptide Ameliorates Brain Injury Following Intracerebral Hemorrhage by Suppressing Astrocyte-Derived Inflammation via the Inhibition of Drp1-Mediated Mitochondrial Fission.
Translational stroke research
Wu X,Luo J,Liu H,Cui W,Guo K,Zhao L,Bai H,Guo W,Guo H,Feng D,Qu Y
PA5-16291 was used in Immunohistochemistry-immunofluorescence to investigate the protective effects of recombinant APN peptide (APNp) on brain injury after ICH in adult male C57BL/6J mice and further explored the underlying molecular mechanisms of these effects.
Thu Oct 01 00:00:00 EDT 2020
Anti-aging effects of Ribes meyeri anthocyanins on neural stem cells and aging mice.
Aging
Gao J,Wu Y,He D,Zhu X,Li H,Liu H,Liu H
Published figure using GFAP polyclonal antibody (Product # PA5-16291) in Immunocytochemistry
Sat Sep 12 00:00:00 EDT 2020
Delayed microglial depletion after spinal cord injury reduces chronic inflammation and neurodegeneration in the brain and improves neurological recovery in male mice.
Theranostics
Li Y,Ritzel RM,Khan N,Cao T,He J,Lei Z,Matyas JJ,Sabirzhanov B,Liu S,Li H,Stoica BA,Loane DJ,Faden AI,Wu J
Published figure using GFAP polyclonal antibody (Product # PA5-16291) in Immunohistochemistry
Tue Jun 01 00:00:00 EDT 2021
Delayed microglial depletion after spinal cord injury reduces chronic inflammation and neurodegeneration in the brain and improves neurological recovery in male mice.
Theranostics
Li Y,Ritzel RM,Khan N,Cao T,He J,Lei Z,Matyas JJ,Sabirzhanov B,Liu S,Li H,Stoica BA,Loane DJ,Faden AI,Wu J
Published figure using GFAP polyclonal antibody (Product # PA5-16291) in Immunohistochemistry
Tue Jun 01 00:00:00 EDT 2021
Delayed microglial depletion after spinal cord injury reduces chronic inflammation and neurodegeneration in the brain and improves neurological recovery in male mice.
Theranostics
Li Y,Ritzel RM,Khan N,Cao T,He J,Lei Z,Matyas JJ,Sabirzhanov B,Liu S,Li H,Stoica BA,Loane DJ,Faden AI,Wu J
Published figure using GFAP polyclonal antibody (Product # PA5-16291) in Immunohistochemistry
Tue Jun 01 00:00:00 EDT 2021
Androgen Deprivation Induces Reprogramming of Prostate Cancer Cells to Stem-Like Cells.
Cells
Sánchez BG,Bort A,Vara-Ciruelos D,Díaz-Laviada I
Published figure using GFAP polyclonal antibody (Product # PA5-16291) in Western Blot
Wed Jun 10 00:00:00 EDT 2020
Androgen Deprivation Induces Reprogramming of Prostate Cancer Cells to Stem-Like Cells.
Cells
Sánchez BG,Bort A,Vara-Ciruelos D,Díaz-Laviada I
Published figure using GFAP polyclonal antibody (Product # PA5-16291) in Western Blot
Wed Jun 10 00:00:00 EDT 2020
Astrocytes shape the plastic response of adult cortical neurons to vision loss.
Glia
Hennes M,Lombaert N,Wahis J,Van den Haute C,Holt MG,Arckens L
PA5-16291 was used in Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot to highlight an integral role for astrocytes in mediating adult cortical plasticity and unmask astrocyte specific Gi signaling as an interesting therapeutic pathway for brain plasticity regulation.
Thu Oct 01 00:00:00 EDT 2020
Metabolic Reprogramming in Astrocytes Distinguishes Region-Specific Neuronal Susceptibility in Huntington Mice.
Cell metabolism
Polyzos AA,Lee DY,Datta R,Hauser M,Budworth H,Holt A,Mihalik S,Goldschmidt P,Frankel K,Trego K,Bennett MJ,Vockley J,Xu K,Gratton E,McMurray CT
PA5-16291 was used in Immunocytochemistry to show that region-specific neuronal vulnerability is a substrate-driven response in astrocytes.
Tue Jun 04 00:00:00 EDT 2019
CPSF1 mutations are associated with early-onset high myopia and involved in retinal ganglion cell axon projection.
Human molecular genetics
Ouyang J,Sun W,Xiao X,Li S,Jia X,Zhou L,Wang P,Zhang Q
PA5-16291 was used in Immunohistochemistry-immunofluorescence to determine the role of CPSF1 mutations in the development of retinal ganglion cell axon projection.
Sat Jun 15 00:00:00 EDT 2019
Modulating Expression of Thioredoxin Interacting Protein (TXNIP) Prevents Secondary Damage and Preserves Visual Function in a Mouse Model of Ischemia/Reperfusion.
International journal of molecular sciences
Coucha M,Shanab AY,Sayed M,Vazdarjanova A,El-Remessy AB
Published figure using GFAP polyclonal antibody (Product # PA5-16291) in Immunohistochemistry
Thu Aug 15 00:00:00 EDT 2019
Modulating Expression of Thioredoxin Interacting Protein (TXNIP) Prevents Secondary Damage and Preserves Visual Function in a Mouse Model of Ischemia/Reperfusion.
International journal of molecular sciences
Coucha M,Shanab AY,Sayed M,Vazdarjanova A,El-Remessy AB
Published figure using GFAP polyclonal antibody (Product # PA5-16291) in Immunohistochemistry
Thu Aug 15 00:00:00 EDT 2019
Modulating Expression of Thioredoxin Interacting Protein (TXNIP) Prevents Secondary Damage and Preserves Visual Function in a Mouse Model of Ischemia/Reperfusion.
International journal of molecular sciences
Coucha M,Shanab AY,Sayed M,Vazdarjanova A,El-Remessy AB
Published figure using GFAP polyclonal antibody (Product # PA5-16291) in Immunohistochemistry
Thu Aug 15 00:00:00 EDT 2019
Neuroprotective effect of nilotinib on pentylenetetrazol-induced epilepsy in adult rat hippocampus: involvement of oxidative stress, autophagy, inflammation, and apoptosis.
Folia neuropathologica
Attia GM,Elmansy RA,Elsaed WM
PA5-16291 was used in Immunohistochemistry to analyze the neuroprotective and antiepileptic effect of nilotinib and explain its mechanism of action.
Thu Feb 20 00:00:00 EST 2020
Zika Virus Targeting in the Developing Brain.
The Journal of neuroscience : the official journal of the Society for Neuroscience
van den Pol AN,Mao G,Yang Y,Ornaghi S,Davis JN
PA5-16291 was used in Immunocytochemistry to suggest that Zika virus infects multiple cell types within the brain and that astrocyte infection may play an important role.
Wed Feb 22 00:00:00 EST 2017
Chronic treatment with resveratrol, a natural polyphenol found in grapes, alleviates oxidative stress and apoptotic cell death in ovariectomized female rats subjected to chronic cerebral hypoperfusion.
Nutritional neuroscience
Ozacmak VH,Sayan-Ozacmak H,Barut F
PA5-16291 was used in immunohistochemistry - paraffin section to study the role of resveratrol treatment during oxidative stress and apoptotic cell death caused be cerebral hypoperfusion in rats
Sun May 01 00:00:00 EDT 2016
Immunopathological changes in the brain of immunosuppressed mice experimentally infected with Toxocara canis.
The Korean journal of parasitology
Eid MM,El-Kowrany SI,Othman AA,El Gendy DI,Saied EM
PA5-16291 was used in immunohistochemistry - paraffin section to study the pathological and immunological changes in the brain of normal and immunosuppressed mice infected with T. canis
Sun Feb 01 00:00:00 EST 2015
Rac1 plays an essential role in axon growth and guidance and in neuronal survival in the central and peripheral nervous systems.
Neural development
Hua ZL,Emiliani FE,Nathans J
PA5-16291 was used in immunohistochemistry to study neuronal survival in the peripheral and central nervous system and axon growth due to the role of Rac1
Wed Sep 23 00:00:00 EDT 2015
Dynamin 2 regulation of integrin endocytosis, but not VEGF signaling, is crucial for developmental angiogenesis.
Development (Cambridge, England)
Lee MY,Skoura A,Park EJ,Landskroner-Eiger S,Jozsef L,Luciano AK,Murata T,Pasula S,Dong Y,Bouaouina M,Calderwood DA,Ferguson SM,De Camilli P,Sessa WC
PA5-16291 was used in immunocytochemistry to study the role of integrin endocytosis in the mechanism underlying dynamin-2-mediated developmental angiogenesis
Tue Apr 01 00:00:00 EDT 2014
Perinatal inflammation results in decreased oligodendrocyte numbers in adulthood.
Life sciences
Graf AE,Haines KM,Pierson CR,Bolon BN,Houston RH,Velten M,Heyob KM,Rogers LK
PA5-16291 was used in immunohistochemistry to study the decreased numbers of oligodendrocytes in adult mice subjected to neonatal inflammation and hyperoxia
Fri Jan 17 00:00:00 EST 2014
Reactive oxygen species induce procalcitonin expression in trigeminal ganglia glia.
Headache
Raddant AC,Russo AF
PA5-16291 was used in immunohistochemistry to study the induction of trigeminal ganglia glial expression of procalcitonin by ROS
Sat Mar 01 00:00:00 EST 2014
Involvement of plasmalogens in post-natal retinal vascular development.
PloS one
Saab S,Buteau B,Leclère L,Bron AM,Creuzot-Garcher CP,Bretillon L,Acar N
PA5-16291 was used in immunohistochemistry to determine the role of post-natal retinal vascular development and plasmalogens
Thu Nov 05 00:00:00 EST 2015
Efficient generation of human iPSCs by a synthetic self-replicative RNA.
Cell stem cell
Yoshioka N,Gros E,Li HR,Kumar S,Deacon DC,Maron C,Muotri AR,Chi NC,Fu XD,Yu BD,Dowdy SF
PA5-16291 was used in immunohistochemistry to develop a synthetic self-replicating RNA replicon expressing reprogramming factors that enables the efficient generation of induced pluripotent stem cells
Thu Aug 01 00:00:00 EDT 2013
Romanowsky-Giemsa as a counterstain for immunohistochemistry: optimizing a traditional reagent.
Biotechnic & histochemistry : official publication of the Biological Stain Commission
Stefanović D,Stefanović M,Nikin Z
PA5-16291 was used in immunohistochemistry to develop a protocol for the counterstaining of immunohistochemical sections using Romanowsky-Giemsa
Thu Aug 01 00:00:00 EDT 2013
Therapeutic and space radiation exposure of mouse brain causes impaired DNA repair response and premature senescence by chronic oxidant production.
Aging
Suman S,Rodriguez OC,Winters TA,Fornace AJ,Albanese C,Datta K
Published figure using GFAP polyclonal antibody (Product # PA5-16291) in Immunohistochemistry
Thu Aug 01 00:00:00 EDT 2013
DCPIB, a specific inhibitor of volume-regulated anion channels (VRACs), inhibits astrocyte proliferation and cell cycle progression via G1/S arrest.
Journal of molecular neuroscience : MN
He D,Luo X,Wei W,Xie M,Wang W,Yu Z
PA5-16291 was used in immunocytochemistry to study the blockade of astrocyte proliferation and cell cycle progression by a VRAC inhibitor
Wed Feb 01 00:00:00 EST 2012
Live imaging of mouse endogenous neural progenitors migrating in response to an induced tumor.
PloS one
Elvira G,García I,Benito M,Gallo J,Desco M,Penadés S,Garcia-Sanz JA,Silva A
PA5-16291 was used in immunohistochemistry to identify endogenous neural precursor cells migrating towards a brain damage site
Thu Feb 14 00:00:00 EST 2013
