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Product Details
PA5-18636
Species Reactivity
Host/Isotype
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Type
Immunogen
Conjugate
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Product Specific Information
This antibody is tested in Peptide ELISA: antibody detection limit dilution 8,000.
Target Information
The protein encoded by this gene is a member of the fibroblast growth factor family. FGF family members possess broad mitogenic and cell survival activities and are involved in a variety of biological processes including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. The product of this gene inhibits renal tubular phosphate transport. This gene was identified by its mutations associated with autosomal dominant hypophosphatemic rickets, an inherited phosphate wasting disorder. Abnormally high level expression of this gene was found in oncogenic hypophosphatemic osteomalacia, a phenotypically similar disease caused by abnormal phosphate metabolism. Mutations in this gene have also been shown to cause familial tumoral calcinosis with hyperphosphatemia.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Bioinformatics
Protein Aliases: FGF; FGF-23; Fibroblast growth factor; Fibroblast growth factor 23; Phosphatonin; tumor-derived hypophosphatemia inducing factor; Tumor-derived hypophosphatemia-inducing factor
Gene Aliases: ADHR; FGF23; FGFN; HPDR2; HYPF; PHPTC; UNQ3027/PRO9828
UniProt ID: (Human) Q9GZV9
Entrez Gene ID: (Human) 8074
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If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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