Product References
Empagliflozin mitigates type 2 diabetes-associated peripheral neuropathy: a glucose-independent effect through AMPK signaling.
Archives of pharmacal research
Abdelkader NF,Elbaset MA,Moustafa PE,Ibrahim SM
61-7400 was used in Western Blotting to explore the potentiality of the selective sodium-glucose cotransporter-2 inhibitor, empagliflozin (EMPA), to ameliorate streptozotocin-induced DPN in rats with insight into its precise signaling mechanism.
Fri Jul 01 00:00:00 EDT 2022
Regulation of Sirtuin-3 and ERK1/2/p38MAPK by the combination Ga nanoparticles/γ-radiation low dosage: an effective approach for treatment of hepatocellular carcinoma.
Journal, genetic engineering & biotechnology
Abdalla MS,El-Mahdy EM,Mansour SZ,Elsonbaty SM,Amin MH
61-7400 was used in Western Blotting to conclude that the combined treatment with GaNPs synthesized by grape seed extract and low dose γ-radiation may have antineoplastic activity against hepatocarcinogenesis by inhibiting signal pathways extracellular signal-regulated kinase/mitogen-activated protein kinase/c-Jun NH2-terminal kinase and stimulating apoptotic protein.
Fri Jul 01 00:00:00 EDT 2022
Cardiac hypertrophy in mice submitted to a swimming protocol: influence of training volume and intensity on myocardial renin-angiotensin system.
American journal of physiology. Regulatory, integrative and comparative physiology
Soares DDS,Pinto GH,Lopes A,Caetano DSL,Nascimento TG,Andrades ME,Clausell N,Rohde LEP,Leitão SAT,Biolo A
61-7400 was used in Sodium dodecyl sulfate polyacrylamide gel electrophoresis to suggest that increasing exercise volume and intensity did not induce a pathological hypertrophy phenotype, but instead improved the oxidative capacity, and this process might have the participation of the RAS alternative axis.
Sat Jun 01 00:00:00 EDT 2019
The role of fibroblast growth factor signalling in Echinococcus multilocularis development and host-parasite interaction.
PLoS neglected tropical diseases
Förster S,Koziol U,Schäfer T,Duvoisin R,Cailliau K,Vanderstraete M,Dissous C,Brehm K
61-7400 was used in Western Blotting to study the molecular mechanisms of parasite organ tropism towards the liver and the influences of liver cytokines and hormones on parasite development.
Fri Mar 01 00:00:00 EST 2019
The role of fibroblast growth factor signalling in Echinococcus multilocularis development and host-parasite interaction.
PLoS neglected tropical diseases
Förster S,Koziol U,Schäfer T,Duvoisin R,Cailliau K,Vanderstraete M,Dissous C,Brehm K
61-7400 was used in Western Blotting to study the molecular mechanisms of parasite organ tropism towards the liver and the influences of liver cytokines and hormones on parasite development.
Fri Mar 01 00:00:00 EST 2019
Acylated Ghrelin and The Regulation of Lipid Metabolism in The Intestine.
Scientific reports
Auclair N,Patey N,Melbouci L,Ou Y,Magri-Tomaz L,Sané A,Garofalo C,Levy E,St-Pierre DH
Published figure using ERK1/ERK2 polyclonal antibody (Product # 61-7400) in Western Blot
Fri Nov 29 00:00:00 EST 2019
CAPN1 is a novel binding partner and regulator of the tumor suppressor NF1 in melanoma.
Oncotarget
Alon M,Arafeh R,Lee JS,Madan S,Kalaora S,Nagler A,Abgarian T,Greenberg P,Ruppin E,Samuels Y
61-7400 was used in Western Blotting to characterise the binding partners of neurofibromin 1 and the pathways in which it is involved in melanoma.
Fri Jul 27 00:00:00 EDT 2018
Downregulation of Lnc-Spry1 mediates TGF-β-induced epithelial-mesenchymal transition by transcriptional and posttranscriptional regulatory mechanisms.
Cell death and differentiation
Rodríguez-Mateo C,Torres B,Gutiérrez G,Pintor-Toro JA
61-7400 was used in Western Blotting to examine the role of long non-coding RNAs as immediate-early regulators of epithelial-to-mesenchymal transition.
Mon May 01 00:00:00 EDT 2017
Iterative Modeling Reveals Evidence of Sequential Transcriptional Control Mechanisms.
Cell systems
Cheng CS,Behar MS,Suryawanshi GW,Feldman KE,Spreafico R,Hoffmann A
61-7400 was used in Western Blotting to develop a mechanistic modelling approach to elucidate transcription factor control logic from gene expression data.
Wed Mar 22 00:00:00 EDT 2017
Extracellular Signal-Regulated Kinase Signaling in CD4-Expressing Cells Inhibits Osteochondromas.
Frontiers in immunology
Wehenkel M,Corr M,Guy CS,Edwards BA,Castellaw AH,Calabrese C,Pagès G,Pouysségur J,Vogel P,McGargill MA
Published figure using ERK1/ERK2 polyclonal antibody (Product # 61-7400) in Western Blot
Sat Apr 09 00:00:00 EDT 2022
Transgenic mice with increased astrocyte expression of IL-6 show altered effects of acute ethanol on synaptic function.
Neuropharmacology
Hernandez RV,Puro AC,Manos JC,Huitron-Resendiz S,Reyes KC,Liu K,Vo K,Roberts AJ,Gruol DL
Published figure using ERK1/ERK2 polyclonal antibody (Product # 61-7400) in Western Blot
Fri Apr 01 00:00:00 EDT 2016
Targeting SALL4 by entinostat in lung cancer.
Oncotarget
Yong KJ,Li A,Ou WB,Hong CK,Zhao W,Wang F,Tatetsu H,Yan B,Qi L,Fletcher JA,Yang H,Soo R,Tenen DG,Chai L
617400 was used in western blot to demonstrate that entinostat targets SALL4-positive lung cancer
Tue Nov 15 00:00:00 EST 2016
Analysis of the V2 Vasopressin Receptor (V2R) Mutations Causing Partial Nephrogenic Diabetes Insipidus Highlights a Sustainable Signaling by a Non-peptide V2R Agonist.
The Journal of biological chemistry
Makita N,Sato T,Yajima-Shoji Y,Sato J,Manaka K,Eda-Hashimoto M,Ootaki M,Matsumoto N,Nangaku M,Iiri T
617400 was used in western blot to characterize a V2 vasopressin receptor mutation found in patient with partial nephrogenic diabetes insipidus
Fri Oct 21 00:00:00 EDT 2016
PARP targeting counteracts gliomagenesis through induction of mitotic catastrophe and aggravation of deficiency in homologous recombination in PTEN-mutant glioma.
Oncotarget
Majuelos-Melguizo J,Rodríguez MI,López-Jiménez L,Rodríguez-Vargas JM,Martí Martín-Consuegra JM,Serrano-Sáenz S,Gavard J,de Almodóvar JM,Oliver FJ
61-7400 was used in western blot to determine the action of PARP inhibition in different glioblastoma multiforme cell lines.
Tue Mar 10 00:00:00 EDT 2015
PARP targeting counteracts gliomagenesis through induction of mitotic catastrophe and aggravation of deficiency in homologous recombination in PTEN-mutant glioma.
Oncotarget
Majuelos-Melguizo J,Rodríguez MI,López-Jiménez L,Rodríguez-Vargas JM,Martí Martín-Consuegra JM,Serrano-Sáenz S,Gavard J,de Almodóvar JM,Oliver FJ
61-7400 was used in western blot to determine the action of PARP inhibition in different glioblastoma multiforme cell lines.
Tue Mar 10 00:00:00 EDT 2015
GPR30 activation is neither necessary nor sufficient for acute neuroprotection by 17β-estradiol after an ischemic injury in organotypic hippocampal slice cultures.
Brain research
Lamprecht MR,Morrison B
61-7400 was used in western blot to examine the role of GPR30 in 7β-estradiol-mediated neuroprotection after an ischemic injury in an organotypic hippocampal slice culture model.
Wed May 14 00:00:00 EDT 2014
CCL2-ethanol interactions and hippocampal synaptic protein expression in a transgenic mouse model.
Frontiers in integrative neuroscience
Gruol DL,Vo K,Bray JG,Roberts AJ
61-7400 was used in western blot to study the effect of ethanol exposure on CCL2 secretion and hippocampal synaptic protein expression
Mon Apr 28 00:00:00 EDT 2014
Increased astrocyte expression of IL-6 or CCL2 in transgenic mice alters levels of hippocampal and cerebellar proteins.
Frontiers in cellular neuroscience
Gruol DL,Vo K,Bray JG
61-7400 was used in western blot to study IL-6 and CCL2 in the central nervous system
Mon Sep 01 00:00:00 EDT 2014
Brain-derived neurotrophic factor protects against cardiac dysfunction after myocardial infarction via a central nervous system-mediated pathway.
Arteriosclerosis, thrombosis, and vascular biology
Okada S,Yokoyama M,Toko H,Tateno K,Moriya J,Shimizu I,Nojima A,Ito T,Yoshida Y,Kobayashi Y,Katagiri H,Minamino T,Komuro I
61-7400 was used in Western Blotting to suggest that brain-derived neurotrophic factor expression is upregulated by heart neural signals after myocardial infarction, protecting the myocardium against ischemic injury.
Wed Aug 01 00:00:00 EDT 2012
Neuroadaptive changes in cerebellar neurons induced by chronic exposure to IL-6.
Journal of neuroimmunology
Gruol DL,Puro A,Hao C,Blakely P,Janneke E,Vo K
61-7400 was used in western blot to study how elevated levels of IL-6 affect neurons.
Fri Oct 28 00:00:00 EDT 2011
Id-1 activates Akt-mediated Wnt signaling and p27(Kip1) phosphorylation through PTEN inhibition.
Oncogene
Lee JY,Kang MB,Jang SH,Qian T,Kim HJ,Kim CH,Kim Y,Kong G
61-7400 was used in western blot to report that Id-1 is a novel PTEN inhibitor
Thu Feb 12 00:00:00 EST 2009
Single and combined silencing of ERK1 and ERK2 reveals their positive contribution to growth signaling depending on their expression levels.
Molecular and cellular biology
Lefloch R,Pouysségur J,Lenormand P
61-7400 was used in western blot to examine the roles of ERK1 and ERK2 in cell proliferation and immediate-early gene expression
Tue Jan 01 00:00:00 EST 2008
Single and combined silencing of ERK1 and ERK2 reveals their positive contribution to growth signaling depending on their expression levels.
Molecular and cellular biology
Lefloch R,Pouysségur J,Lenormand P
61-7400 was used in western blot to examine the roles of ERK1 and ERK2 in cell proliferation and immediate-early gene expression
Tue Jan 01 00:00:00 EST 2008
Chronic CXCL10 alters the level of activated ERK1/2 and transcriptional factors CREB and NF-kappaB in hippocampal neuronal cell culture.
Journal of neuroimmunology
Bajova H,Nelson TE,Gruol DL
61-7400 was used in immunocytochemistry to assess the effects of chronic CXCL10 exposure on neuronal/glial cell cultures
Sat Mar 01 00:00:00 EST 2008
Chronic CXCL10 alters the level of activated ERK1/2 and transcriptional factors CREB and NF-kappaB in hippocampal neuronal cell culture.
Journal of neuroimmunology
Bajova H,Nelson TE,Gruol DL
61-7400 was used in immunocytochemistry to assess the effects of chronic CXCL10 exposure on neuronal/glial cell cultures
Sat Mar 01 00:00:00 EST 2008
Chronic CXCL10 alters the level of activated ERK1/2 and transcriptional factors CREB and NF-kappaB in hippocampal neuronal cell culture.
Journal of neuroimmunology
Bajova H,Nelson TE,Gruol DL
61-7400 was used in immunocytochemistry to assess the effects of chronic CXCL10 exposure on neuronal/glial cell cultures
Sat Mar 01 00:00:00 EST 2008
Inhibitor of DNA binding 1 activates vascular endothelial growth factor through enhancing the stability and activity of hypoxia-inducible factor-1alpha.
Molecular cancer research : MCR
Kim HJ,Chung H,Yoo YG,Kim H,Lee JY,Lee MO,Kong G
61-7400 was used in Western Blotting to provide the molecular mechanism of the cross talk between hypoxia-inducible factor-1alpha and Inhibitor of DNA binding 1, which may be critical in tumour angiogenesis.
Sun Apr 01 00:00:00 EDT 2007
In situ analysis of integrin and growth factor receptor signaling pathways in human glioblastomas suggests overlapping relationships with focal adhesion kinase activation.
The American journal of pathology
Riemenschneider MJ,Mueller W,Betensky RA,Mohapatra G,Louis DN
61-7400 was used in immunohistochemistry - paraffin section to study focal adhesion kinase and extracellular regulated kinases in glioblastomas
Tue Nov 01 00:00:00 EST 2005
A role for mitogen-activated protein kinase(Erk1/2) activation and non-selective pore formation in P2X7 receptor-mediated thymocyte death.
The Journal of biological chemistry
Auger R,Motta I,Benihoud K,Ojcius DM,Kanellopoulos JM
61-7400 was used in western blot to study P2X7 receptor-mediated thymocyte death and the role for mitogen-activated protein kinase (Erk1/2) activation and non-selective pore formation
Fri Jul 29 00:00:00 EDT 2005
Conditional, tissue-specific expression of Q205L Galphai2 in vivo mimics insulin activation of c-Jun N-terminal kinase and p38 kinase.
The Journal of biological chemistry
Guo JH,Wang HY,Malbon CC
61-7400 was used in western blot to use transgenic mice to study the effect of tissue-specific expression of the constitutively active mutant form (Q205L) of Galphai2.
Fri Jun 26 00:00:00 EDT 1998
