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Product Details
18343-1-AP
Species Reactivity
Published species
Host/Isotype
Class
Type
Immunogen
Conjugate
Form
Concentration
Purification
Storage buffer
Contains
Storage conditions
Shipping conditions
Product Specific Information
Immunogen sequence: RLKYENEVA LRQSVEADIN GLRRVLDELT LTKADLEMQI ESLTEELAYL KKNHEEEMKD LRNVSTGDVN VEMNAAPGVD LTQLLNNMRS QYEQLAEQNR KDAEAWFNEK SKELTTEIDN NIEQISSYKS EITELRRNVQ ALEIELQSQL ALKQSLEASL AETEGRYCVQ LSQIQAQISA LEEQLQQIRA ETECQNTEYQ QLLDIKIRLE NEIQTYRSLL EGEGSSGGGG RGGGSFGGGY GGGSSGGGSS GGGYGGGHGG SSGGGYGGGS SGGGSSGGGY GGGSSSGGHG GSSSGGYGGG SSGGGGGGYG GGSSGGGSSS GGGYGGGSSS GGHKSSSSGS VGESSSKGPR Y (235-584 aa encoded by BC034697)
Target Information
Cytokeratins (CK) are intermediate filaments of epithelial cells, both in keratinizing tissue (i.e., skin) and non-keratinizing cells (i.e. mesothelial cells). Although not a traditional marker for endothelial cells, cytokeratins have also been found in some microvascular endothelial cells. At least 20 different cytokeratins (CK) in the molecular range of 40-70 kDa and isoelectric points of 5-8. 5 can be identified using two dimensional gel electrophoresis. Biochemically, most members of the CK family fall into one of two classes, type I (acidic polypeptides) and type II (basic polypeptides). At least one member of the acidic family and one member of the basic family is expressed in all epithelial cells. Monoclonal antibodies to cytokeratin proteins can be useful markers for tumor identification and classification.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: 56 kDa cytokeratin; CK-10; cytokeratin 10; Cytokeratin-10; cytokeratin-17; epidermal keratin 10; intermediate filament protein; K10; keratin 10, type I; keratin complex 1, acidic, gene 10; Keratin, type I cytoskeletal 10; Keratin, type I cytoskeletal 59 kDa; Keratin-10; keratin-17; krt10 {ECO:0000250|UniProtKB:P13645}; suprabasal cytokeratin 10; type I keratin KA10
Gene Aliases: BCIE; BIE; CK10; D130054E02Rik; EHK; K10; K1C1; Ka10; KPP; Krt-1.10; Krt1-10; KRT10
UniProt ID: (Human) P13645, (Mouse) P02535
Entrez Gene ID: (Human) 3858, (Mouse) 16661, (Rat) 450225
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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