Product References
On Immunological Studies at Sirius University of Science and Technology.
Molecular biology
Astrakhantseva IV,Krut' VG,Chuvpilo SA,Shevyrev DV,Shumeev AN,Rybtsov SA,Nedospasov SA
17-0088-42 was used in Flow cytometry/Cell sorting to summarize the results of recent immunological studies performed at new Sirius University of Science and Technology.
Wed May 03 00:00:00 EDT 2023
VLA-4 suppression by senescence signals regulates meningeal immunity and leptomeningeal metastasis.
eLife
Li J,Huang D,Lei B,Huang J,Yang L,Nie M,Su S,Zhao Q,Wang Y
17-0088-42 was used in Flow Cytometry to demonstrate that CD8+ T cell immunosenescence drives leptomeningeal metastasis.
Fri Dec 09 00:00:00 EST 2022
Immunometabolic analysis shows a distinct cyto-metabotype in Covid-19 compared to sepsis from other causes.
Heliyon
Trovato FM,Mujib S,Jerome E,Cavazza A,Morgan P,Smith J,Depante MT,O'Reilly K,Luxton J,Mare T,Napoli S,McPhail MJ
17-0088-42 was used in Flow cytometry/Cell sorting to support the hypothesis that IFN-γ -PD-L1 axis might be involved in the cytokine release syndrome typical of severe Covid-19 and the phenomenon persisted through multiple pandemic waves despite use of immunomodulation.
Wed Jun 01 00:00:00 EDT 2022
PRDM1/BLIMP1 induces cancer immune evasion by modulating the USP22-SPI1-PD-L1 axis in hepatocellular carcinoma cells.
Nature communications
Li Q,Zhang L,You W,Xu J,Dai J,Hua D,Zhang R,Yao F,Zhou S,Huang W,Dai Y,Zhang Y,Baheti T,Qian X,Pu L,Xu J,Xia Y,Zhang C,Tang J,Wang X
17-0088-42 was used in Flow cytometry/Cell sorting to demonstrate that the PRDM1-USP22-SPI1 axis regulates PD-L1 levels, resulting in infiltrated CD8+ T cell exhaustion.
Mon Dec 12 00:00:00 EST 2022
Distinct roles of programmed death ligand 1 alternative splicing isoforms in colorectal cancer.
Cancer science
Wang C,Weng M,Xia S,Zhang M,Chen C,Tang J,Huang D,Yu H,Sun W,Zhang H,Lai M
17-0088 was used in Flow cytometry/Cell sorting to explore the distinct functions of different PD-L1 alternative splicing isoforms in CRC.
Fri Jan 01 00:00:00 EST 2021
Severe T cell hyporeactivity in ventilated COVID-19 patients correlates with prolonged virus persistence and poor outcomes.
Nature communications
Renner K,Schwittay T,Chaabane S,Gottschling J,Müller C,Tiefenböck C,Salewski JN,Winter F,Buchtler S,Balam S,Malfertheiner MV,Lubnow M,Lunz D,Graf B,Hitzenbichler F,Hanses F,Poeck H,Kreutz M,Orsó E,Burkhardt R,Niedermair T,Brochhausen C,Gessner A,Salzberger B,Mack M
Published figure using CD8a monoclonal antibody (Product # 17-0088-42) in Flow Cytometry
Fri May 21 00:00:00 EDT 2021
Changes of immune cells in patients with hepatocellular carcinoma treated by radiofrequency ablation and hepatectomy, a pilot study.
Open life sciences
Yu Z,Li G,Yu H,Asakawa T
Published figure using CD8a monoclonal antibody (Product # 17-0088-42) in Immunohistochemistry
Fri Feb 18 00:00:00 EST 2022
Multipeptide stimulated PBMCs generate TEM/TCM for adoptive cell therapy in multiple myeloma.
Oncotarget
Vardam-Kaur T,Pathangey LB,McCormick DJ,Bergsagel PL,Cohen PA,Gendler SJ
Published figure using CD8a monoclonal antibody (Product # 17-0088-42) in Flow Cytometry
Tue Sep 28 00:00:00 EDT 2021
Human endoglin-CD3 bispecific T cell engager antibody induces anti-tumor effect in vivo.
Theranostics
Zhong L,Shi W,Gan L,Liu X,Huo Y,Wu P,Zhang Z,Wu T,Peng H,Huang Y,Zhao Y,Yuan Y,Deng Z,Tang H
Published figure using CD8a monoclonal antibody (Product # 17-0088-42) in Flow Cytometry
Wed Jul 28 00:00:00 EDT 2021
TCR function analysis using a novel system reveals the multiple unconventional tumor-reactive T cells in human breast cancer-infiltrating lymphocytes.
European journal of immunology
Yamaguchi S,Hamana H,Shitaoka K,Sukegawa K,Nagata T,Hayee A,Kobayashi E,Ozawa T,Fujii T,Muraguchi A,Tobe K,Kishi H
17-0088-42 was used in Flow cytometry/Cell sorting to develop an efficient evaluation system for TCR function designated c-FIT (comprehensive functional investigation of TCRs) to analyze TCR reactivity.
Wed Sep 01 00:00:00 EDT 2021
Bispecific T-Cell Engaging Antibodies Against MUC16 Demonstrate Efficacy Against Ovarian Cancer in Monotherapy and in Combination With PD-1 and VEGF Inhibition.
Frontiers in immunology
Yeku OO,Rao TD,Laster I,Kononenko A,Purdon TJ,Wang P,Cui Z,Liu H,Brentjens RJ,Spriggs D
Published figure using CD8a monoclonal antibody (Product # 17-0088-42) in Flow Cytometry
Thu Oct 21 00:00:00 EDT 2021
Preventing ATP Degradation by ASO-Mediated Knockdown of CD39 and CD73 Results in A2aR-Independent Rescue of T Cell Proliferation.
Molecular therapy. Nucleic acids
Festag J,Thelemann T,Schell M,Raith S,Michel S,Jaschinski F,Klar R
Published figure using CD8a monoclonal antibody (Product # 17-0088-42) in Flow Cytometry
Fri Sep 04 00:00:00 EDT 2020
Preventing ATP Degradation by ASO-Mediated Knockdown of CD39 and CD73 Results in A2aR-Independent Rescue of T Cell Proliferation.
Molecular therapy. Nucleic acids
Festag J,Thelemann T,Schell M,Raith S,Michel S,Jaschinski F,Klar R
Published figure using CD8a monoclonal antibody (Product # 17-0088-42) in Flow Cytometry
Fri Sep 04 00:00:00 EDT 2020
Relationship between T cell receptor clonotype and PD-1 expression of tumor-infiltrating lymphocytes in colorectal cancer.
European journal of immunology
Sukegawa K,Shitaoka K,Hamana H,Kobayashi E,Miyahara Y,Fujii K,Tsuda K,Saeki S,Nagata T,Ozawa T,Saito S,Fujii T,Muraguchi A,Shiku H,Kishi H
Published figure using CD8a monoclonal antibody (Product # 17-0088-42) in Flow Cytometry
Thu Oct 01 00:00:00 EDT 2020
A Cross-Reactive Small Protein Binding Domain Provides a Model to Study Off-Tumor CAR-T Cell Toxicity.
Molecular therapy oncolytics
Hammill JA,Kwiecien JM,Dvorkin-Gheva A,Lau VWC,Baker C,Wu Y,Bezverbnaya K,Aarts C,Heslen CW,Denisova GF,Derocher H,Milne K,Nelson BH,Bramson JL
Published figure using CD8a monoclonal antibody (Product # 17-0088-42) in Flow Cytometry
Fri Jun 26 00:00:00 EDT 2020
NKG2Cpos NK Cells Regulate the Expansion of Cytomegalovirus-Specific CD8 T Cells.
Journal of immunology (Baltimore, Md. : 1950)
Grutza R,Moskorz W,Senff T,Bäcker E,Lindemann M,Zimmermann A,Uhrberg M,Lang PA,Timm J,Cosmovici C
17-0088-42 was used in Flow Cytometry to show that NKG2Cpos NK cells interact with HLA-Ehigh CD8 T cells, which may negatively regulate the expansion of CMV-specific CD8 T cells upon activation.
Mon Jun 01 00:00:00 EDT 2020
Mycoplasma Ocular Infection in Subretinal Graft Transplantation of iPS Cells-Derived Retinal Pigment Epithelial Cells.
Investigative ophthalmology & visual science
Makabe K,Sugita S,Hono A,Kamao H,Takahashi M
17-0088 was used in Flow cytometry/Cell sorting to study the immunopatholgical mechanisms of acute severe inflammation following surgical implantation of mycolplasma-infected induced pluripotent stem cell-derived RPE cells into the eyes of primates.
Mon Apr 01 00:00:00 EDT 2019
Immunological Properties of Neural Crest Cells Derived from Human Induced Pluripotent Stem Cells.
Stem cells and development
Fujii S,Yoshida S,Inagaki E,Hatou S,Tsubota K,Takahashi M,Shimmura S,Sugita S
Published figure using CD8a monoclonal antibody (Product # 17-0088-42) in Flow Cytometry
Tue Jan 01 00:00:00 EST 2019
CLEC10A Is a Specific Marker for Human CD1c+ Dendritic Cells and Enhances Their Toll-Like Receptor 7/8-Induced Cytokine Secretion.
Frontiers in immunology
Heger L,Balk S,Lühr JJ,Heidkamp GF,Lehmann CHK,Hatscher L,Purbojo A,Hartmann A,Garcia-Martin F,Nishimura SI,Cesnjevar R,Nimmerjahn F,Dudziak D
17-0088 was used in Flow cytometry/Cell sorting to identify CLEC10A as a specific marker for human CD1c+ dendritic cells and that this rapidly internalises into human CD1c dendritic cells upon binding of a monoclonal antibody directed against CLEC10A.
Thu Jun 13 00:00:00 EDT 2019
The Effects of High Mobility Group Box-1 Protein on Peripheral Treg/Th17 Balance in Patients with Atherosclerosis.
Acta Cardiologica Sinica
Ding JW,Zhou T,Zheng XX,Wang XA,Tong XH,Luo CY,Zhang ZQ,Yu B
17-0088 was used in Flow cytometry/Cell sorting to explore the mechanism of regulatory T cell/Th17 imbalance and the role of high mobility group box-1 protein on the balance in atherosclerosis.
Sat Sep 01 00:00:00 EDT 2018
Blocking the recruitment of naive CD4+ T cells reverses immunosuppression in breast cancer.
Cell research
Su S,Liao J,Liu J,Huang D,He C,Chen F,Yang L,Wu W,Chen J,Lin L,Zeng Y,Ouyang N,Cui X,Yao H,Su F,Huang JD,Lieberman J,Liu Q,Song E
Published figure using CD8a monoclonal antibody (Product # 17-0088-42) in Flow Cytometry
Sat Apr 01 00:00:00 EDT 2017
Using DR52c/Ni2+ mimotope tetramers to detect Ni2+ reactive CD4+ T cells in patients with joint replacement failure.
Toxicology and applied pharmacology
Zhang Y,Wang Y,Anderson K,Novikov A,Liu Z,Pacheco K,Dai S
Fri Sep 15 00:00:00 EDT 2017
Detection of Retinal Pigment Epithelium-Specific Antibody in iPSC-Derived Retinal Pigment Epithelium Transplantation Models.
Stem cell reports
Sugita S,Makabe K,Fujii S,Iwasaki Y,Kamao H,Shiina T,Ogasawara K,Takahashi M
Tue Nov 14 00:00:00 EST 2017
Follicular Regulatory CD8 T Cells Impair the Germinal Center Response in SIV and Ex Vivo HIV Infection.
PLoS pathogens
Miles B,Miller SM,Folkvord JM,Levy DN,Rakasz EG,Skinner PJ,Connick E
Published figure using CD8a monoclonal antibody (Product # 17-0088-42) in Flow Cytometry
Sat Oct 01 00:00:00 EDT 2016
Human Head and Neck Squamous Cell Carcinoma-Associated Semaphorin 4D Induces Expansion of Myeloid-Derived Suppressor Cells.
Journal of immunology (Baltimore, Md. : 1950)
Younis RH,Han KL,Webb TJ
Published figure using CD8a monoclonal antibody (Product # 17-0088-42) in Flow Cytometry
Mon Feb 01 00:00:00 EST 2016
Umbilical Cord-Derived Mesenchymal Stem Cells Suppress Autophagy of T Cells in Patients with Systemic Lupus Erythematosus via Transfer of Mitochondria.
Stem cells international
Chen J,Wang Q,Feng X,Zhang Z,Geng L,Xu T,Wang D,Sun L
Published figure using CD8a monoclonal antibody (Product # 17-0088-42) in Flow Cytometry
Thu Oct 01 00:00:00 EDT 2020
CD28 family of receptors on T cells in chronic HBV infection: Expression characteristics, clinical significance and correlations with PD-1 blockade.
Molecular medicine reports
Tang ZS,Hao YH,Zhang EJ,Xu CL,Zhou Y,Zheng X,Yang DL
17-0088 was used in Flow cytometry/Cell sorting to investigate the expression characteristics and clinical significance of CD28, PD-1, CTLA4 and BTLA on T-cells in patients with chronic HBV and the correlations among these receptors.
Mon Aug 01 00:00:00 EDT 2016
Lack of T Cell Response to iPSC-Derived Retinal Pigment Epithelial Cells from HLA Homozygous Donors.
Stem cell reports
Sugita S,Iwasaki Y,Makabe K,Kimura T,Futagami T,Suegami S,Takahashi M
Published figure using CD8a monoclonal antibody (Product # 17-0088-42) in Flow Cytometry
Tue Oct 11 00:00:00 EDT 2016
The upregulation of LAG-3 on T cells defines a subpopulation with functional exhaustion and correlates with disease progression in HIV-infected subjects.
Journal of immunology (Baltimore, Md. : 1950)
Tian X,Zhang A,Qiu C,Wang W,Yang Y,Qiu C,Liu A,Zhu L,Yuan S,Hu H,Wang W,Wei Q,Zhang X,Xu J
17-0088 was used in Flow cytometry/Cell sorting to study the role of LAG-3 on T cell functionality during persistent HIV-1 infection.
Wed Apr 15 00:00:00 EDT 2015
Durable complete responses off all treatment in patients with metastatic malignant melanoma after sequential immunotherapy followed by a finite course of BRAF inhibitor therapy.
Cancer biology & therapy
Wyluda EJ,Cheng J,Schell TD,Haley JS,Mallon C,Neves RI,Robertson G,Sivik J,Mackley H,Talamo G,Drabick JJ
17-0088 was used in Flow cytometry/Cell sorting to study the effectiveness of different therapy regimes on treating melanoma after failure of immunotherapy.
Tue Mar 01 00:00:00 EST 2016
Liposomal Glutathione Supplementation Restores TH1 Cytokine Response to Mycobacterium tuberculosis Infection in HIV-Infected Individuals.
Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research
Ly J,Lagman M,Saing T,Singh MK,Tudela EV,Morris D,Anderson J,Daliva J,Ochoa C,Patel N,Pearce D,Venketaraman V
Published figure using CD8a monoclonal antibody (Product # 17-0088-42) in Flow Cytometry
Sun Nov 01 00:00:00 EDT 2015
The TB-specific CD4(+) T cell immune repertoire in both cynomolgus and rhesus macaques largely overlap with humans.
Tuberculosis (Edinburgh, Scotland)
Mothé BR,Lindestam Arlehamn CS,Dow C,Dillon MBC,Wiseman RW,Bohn P,Karl J,Golden NA,Gilpin T,Foreman TW,Rodgers MA,Mehra S,Scriba TJ,Flynn JL,Kaushal D,O'Connor DH,Sette A
17-0088-42 was used in Flow Cytometry to reveal an unexpected general repertoire overlap between MHC class II epitopes recognized in both species of macaques and in humans, with general implications for the evaluation of new vaccines and diagnostics in NHPs.
Tue Dec 01 00:00:00 EST 2015
Follicular regulatory T cells impair follicular T helper cells in HIV and SIV infection.
Nature communications
Miles B,Miller SM,Folkvord JM,Kimball A,Chamanian M,Meditz AL,Arends T,McCarter MD,Levy DN,Rakasz EG,Skinner PJ,Connick E
Published figure using CD8a monoclonal antibody (Product # 17-0088-42) in Flow Cytometry
Tue Oct 20 00:00:00 EDT 2015
RSV-specific airway resident memory CD8+ T cells and differential disease severity after experimental human infection.
Nature communications
Jozwik A,Habibi MS,Paras A,Zhu J,Guvenel A,Dhariwal J,Almond M,Wong EHC,Sykes A,Maybeno M,Del Rosario J,Trujillo-Torralbo MB,Mallia P,Sidney J,Peters B,Kon OM,Sette A,Johnston SL,Openshaw PJ,Chiu C
Published figure using CD8a monoclonal antibody (Product # 17-0088-42) in Flow Cytometry
Mon Dec 21 00:00:00 EST 2015
Investigating the causes for decreased levels of glutathione in individuals with type II diabetes.
PloS one
Lagman M,Ly J,Saing T,Kaur Singh M,Vera Tudela E,Morris D,Chi PT,Ochoa C,Sathananthan A,Venketaraman V
Published figure using CD8a monoclonal antibody (Product # 17-0088-42) in Flow Cytometry
Wed Dec 30 00:00:00 EST 2015
Immune response to JC virus T antigen in patients with and without colorectal neoplasia.
Gut microbes
Butcher LD,Garcia M,Arnold M,Ueno H,Goel A,Boland CR
Published figure using CD8a monoclonal antibody (Product # 17-0088-42) in Flow Cytometry
Tue Jul 01 00:00:00 EDT 2014
CD4+CD25(high), CD8+CD28- cells and thyroid autoantibodies in breast cancer patients.
Central-European journal of immunology
Biylgi O,Karagöz B,Türken O,Gültepe M,Özgün A,Tunçel T,Emirzeoğlu L,Çelik S,Müftüoğlu T,Gökhan Kandemir E
Published figure using CD8a monoclonal antibody (Product # 17-0088-42) in Flow Cytometry
Thu Jul 09 00:00:00 EDT 2015
Inhibition of CXCR3-mediated chemotaxis by the human chemokine receptor-like protein CCX-CKR.
British journal of pharmacology
Vinet J,van Zwam M,Dijkstra IM,Brouwer N,van Weering HR,Watts A,Meijer M,Fokkens MR,Kannan V,Verzijl D,Vischer HF,Smit MJ,Leurs R,Biber K,Boddeke HW
17-0088 was used in Flow cytometry/Cell sorting to study the role of hCCX-CKR in hCXCR3-induced chemotaxis.
Fri Mar 01 00:00:00 EST 2013
Assessment of immune interference, antagonism, and diversion following human immunization with biallelic blood-stage malaria viral-vectored vaccines and controlled malaria infection.
Journal of immunology (Baltimore, Md. : 1950)
Elias SC,Collins KA,Halstead FD,Choudhary P,Bliss CM,Ewer KJ,Sheehy SH,Duncan CJ,Biswas S,Hill AV,Draper SJ
17-0088 was used in Flow cytometry/Cell sorting to study the effects of both controlled malaria infection, and human immunisation with biallelic blood-stage malaria viral-vectored vaccines, on the immune system.
Fri Feb 01 00:00:00 EST 2013
Ex vivo analysis of resident hepatic pro-inflammatory CD1d-reactive T cells and hepatocyte surface CD1d expression in hepatitis C.
Journal of viral hepatitis
Yanagisawa K,Yue S,van der Vliet HJ,Wang R,Alatrakchi N,Golden-Mason L,Schuppan D,Koziel MJ,Rosen HR,Exley MA
Published figure using CD8a monoclonal antibody (Product # 17-0088-42) in Flow Cytometry
Thu Aug 01 00:00:00 EDT 2013
Myeloid suppressor cells induced by hepatitis C virus suppress T-cell responses through the production of reactive oxygen species.
Hepatology (Baltimore, Md.)
Tacke RS,Lee HC,Goh C,Courtney J,Polyak SJ,Rosen HR,Hahn YS
17-0088 was used in Flow cytometry/Cell sorting to examine the mechanism for HCV-mediated T-cell dysfunction.
Wed Feb 01 00:00:00 EST 2012
Calcineurin inhibitor treatment of intravenous immunoglobulin-resistant Kawasaki disease.
The Journal of pediatrics
Tremoulet AH,Pancoast P,Franco A,Bujold M,Shimizu C,Onouchi Y,Tamamoto A,Erdem G,Dodd D,Burns JC
17-0088 was used in Flow cytometry/Cell sorting to investigate treatment of refractory KD with a calcineurin inhibitor.
Sat Sep 01 00:00:00 EDT 2012
Upregulation of programmed death-1 on T cells and programmed death ligand-1 on monocytes in septic shock patients.
Critical care (London, England)
Zhang Y,Li J,Lou J,Zhou Y,Bo L,Zhu J,Zhu K,Wan X,Cai Z,Deng X
17-0088 was used in Flow cytometry/Cell sorting to demonstrate that lymphocyte apoptosis is markedly increased in septic shock patients, and suggest an essential role for the PD-1/PD-L1 pathway in sepsis-induced immunosuppression.
Wed Dec 07 00:00:00 EST 2011
Memory T-cells and characterization of peripheral T-cell clones in acute Kawasaki disease.
Autoimmunity
Franco A,Shimizu C,Tremoulet AH,Burns JC
17-0088 was used in Flow cytometry/Cell sorting to provide insight into the nature and kinetics of the adaptive immune response in Kawasaki disease.
Tue Jun 01 00:00:00 EDT 2010
Sepsis-induced human lymphocyte apoptosis and cytokine production in "humanized" mice.
Journal of leukocyte biology
Unsinger J,McDonough JS,Shultz LD,Ferguson TA,Hotchkiss RS
Published figure using CD8a monoclonal antibody (Product # 17-0088-42) in Flow Cytometry
Sat Aug 01 00:00:00 EDT 2009
B cells and monocytes from patients with active multiple sclerosis exhibit increased surface expression of both HERV-H Env and HERV-W Env, accompanied by increased seroreactivity.
Retrovirology
Brudek T,Christensen T,Aagaard L,Petersen T,Hansen HJ,Møller-Larsen A
Published figure using CD8a monoclonal antibody (Product # 17-0088-42) in Flow Cytometry
Mon Nov 16 00:00:00 EST 2009
The proapoptotic factors Bax and Bak regulate T Cell proliferation through control of endoplasmic reticulum Ca(2+) homeostasis.
Immunity
Jones RG,Bui T,White C,Madesh M,Krawczyk CM,Lindsten T,Hawkins BJ,Kubek S,Frauwirth KA,Wang YL,Conway SJ,Roderick HL,Bootman MD,Shen H,Foskett JK,Thompson CB
17-0088 was used in Flow cytometry/Cell sorting to establish the role of Bax and Bak in viable T cell function.
Wed Aug 01 00:00:00 EDT 2007
Specific recruitment of CC chemokine receptor 4-positive regulatory T cells in Hodgkin lymphoma fosters immune privilege.
Cancer research
Ishida T,Ishii T,Inagaki A,Yano H,Komatsu H,Iida S,Inagaki H,Ueda R
17-0088 was used in Flow cytometry/Cell sorting to investigate the contribution of nontumour cells to Hodgkin lymphoma pathogenesis.
Thu Jun 01 00:00:00 EDT 2006
