Product References
A platinum@polymer-catechol nanobraker enables radio-immunotherapy for crippling melanoma tumorigenesis, angiogenesis, and radioresistance.
Bioactive materials
Li W,Yan J,Tian H,Li B,Wang G,Sang W,Zhang Z,Zhang X,Dai Y
Published figure using CD62L (L-Selectin) monoclonal antibody (Product # 25-0621-82) in Flow Cytometry
Sat Apr 01 00:00:00 EDT 2023
Microbiota-assisted iron uptake promotes immune tolerance in the intestine.
Nature communications
Zhu L,Li G,Liang Z,Qi T,Deng K,Yu J,Peng Y,Zheng J,Song Y,Chang X
25-0621-82 was used in Flow cytometry/Cell sorting to reveal an association between nutrient uptake and immune tolerance in the intestine.
Mon May 15 00:00:00 EDT 2023
Microbiota-assisted iron uptake promotes immune tolerance in the intestine.
Nature communications
Zhu L,Li G,Liang Z,Qi T,Deng K,Yu J,Peng Y,Zheng J,Song Y,Chang X
25-0621-82 was used in Flow cytometry/Cell sorting to reveal an association between nutrient uptake and immune tolerance in the intestine.
Mon May 15 00:00:00 EDT 2023
Lin28B-high breast cancer cells promote immune suppression in the lung pre-metastatic niche via exosomes and support cancer progression.
Nature communications
Qi M,Xia Y,Wu Y,Zhang Z,Wang X,Lu L,Dai C,Song Y,Xu K,Ji W,Zhan L
Published figure using CD62L (L-Selectin) monoclonal antibody (Product # 25-0621-82) in Flow Cytometry
Wed Feb 16 00:00:00 EST 2022
Amphiphile-CpG vaccination induces potent lymph node activation and COVID-19 immunity in mice and non-human primates.
NPJ vaccines
Seenappa LM,Jakubowski A,Steinbuck MP,Palmer E,Haqq CM,Carter C,Fontenot J,Villinger F,McNeil LK,DeMuth PC
Published figure using CD62L (L-Selectin) monoclonal antibody (Product # 25-0621-82) in Flow Cytometry
Fri Oct 28 00:00:00 EDT 2022
Foxo3a tempers excessive glutaminolysis in activated T cells to prevent fatal gut inflammation in the murine IL-10-/- model of colitis.
Cell death and differentiation
Hajjar S,Nathan N,Joseph J,Mottawea W,Ariana A,Pyatibrat S,Harper ME,Alain T,Blais A,Russell RC,Sad S
25-0621-82 was used in Flow cytometry/Cell sorting to show that Foxo3a restricts the abundance of colitogenic microbiota in IL-10-deficient mice.
Tue Mar 01 00:00:00 EST 2022
Liver X receptor beta deficiency attenuates autoimmune-associated neuroinflammation in a T cell-dependent manner.
Journal of autoimmunity
Bogie JFJ,Vanmierlo T,Vanmol J,Timmermans S,Mailleux J,Nelissen K,Wijnands E,Wouters K,Stinissen P,Gustafsson JÅ,Steffensen KR,Mulder M,Zelcer N,Hendriks JJA
25-0621-82 was used in Flow cytometry/Cell sorting to show that LXRα and LXRβ have an opposite impact on immune cell function and disease severity in the experimental autoimmune encephalomyelitis model, an experimental multiple sclerosis model.
Mon Nov 01 00:00:00 EDT 2021
Low immunogenicity of malaria pre-erythrocytic stages can be overcome by vaccination.
EMBO molecular medicine
Müller K,Gibbins MP,Roberts M,Reyes-Sandoval A,Hill AVS,Draper SJ,Matuschewski K,Silvie O,Hafalla JCR
Published figure using CD62L (L-Selectin) monoclonal antibody (Product # 25-0621-82) in Flow Cytometry
Fri Apr 09 00:00:00 EDT 2021
Low immunogenicity of malaria pre-erythrocytic stages can be overcome by vaccination.
EMBO molecular medicine
Müller K,Gibbins MP,Roberts M,Reyes-Sandoval A,Hill AVS,Draper SJ,Matuschewski K,Silvie O,Hafalla JCR
Published figure using CD62L (L-Selectin) monoclonal antibody (Product # 25-0621-82) in Flow Cytometry
Fri Apr 09 00:00:00 EDT 2021
DNA Methylation Patterns in T Cells of Naïve and Influenza A Virus-Infected Mice Developmentally Exposed to an Aryl Hydrocarbon Receptor Ligand.
Environmental health perspectives
Burke CG,Myers JR,Post CM,Boulé LA,Lawrence BP
25-0621-82 was used in Flow Cytometry to identify cellular mechanisms that drive impaired CD4+ T-cell responses later in life following maternal exposure to an exogenous aryl hydrocarbon receptor. ligand.
Fri Jan 01 00:00:00 EST 2021
Ageing promotes early T follicular helper cell differentiation by modulating expression of RBPJ.
Aging cell
Webb LMC,Fra-Bido S,Innocentin S,Matheson LS,Attaf N,Bignon A,Novarino J,Fazilleau N,Linterman MA
25-0621-82 was used in Flow Cytometry to show increased formation of Tfh precursors (pre-Tfh) but no associated increase in germinal centre (GC)-Tfh cells in aged mice, suggesting age-driven promotion of only early Tfh cell differentiation.
Fri Jan 01 00:00:00 EST 2021
Sirt6 Regulates the Development of Medullary Thymic Epithelial Cells and Contributes to the Establishment of Central Immune Tolerance.
Frontiers in cell and developmental biology
Zhang Q,Liang Z,Zhang J,Lei T,Dong X,Su H,Chen Y,Zhang Z,Tan L,Zhao Y
Published figure using CD62L (L-Selectin) monoclonal antibody (Product # 25-0621-82) in Flow Cytometry
Wed Apr 21 00:00:00 EDT 2021
Trichinella spiralis Paramyosin Induces Colonic Regulatory T Cells to Mitigate Inflammatory Bowel Disease.
Frontiers in cell and developmental biology
Hao C,Wang W,Zhan B,Wang Z,Huang J,Sun X,Zhu X
Published figure using CD62L (L-Selectin) monoclonal antibody (Product # 25-0621-82) in Flow Cytometry
Tue Aug 03 00:00:00 EDT 2021
CD8+ T cells in the central nervous system of mice with herpes simplex infection are highly activated and express high levels of CCR5 and CXCR3.
Journal of neurovirology
Lind L,Svensson A,Thörn K,Krzyzowska M,Eriksson K
Published figure using CD62L (L-Selectin) monoclonal antibody (Product # 25-0621-82) in Flow Cytometry
Mon Feb 01 00:00:00 EST 2021
cDC1 Dependent Accumulation of Memory T Cells Is Required for Chronic Autoimmune Inflammation in Murine Testis.
Frontiers in immunology
Jing Y,Cao M,Zhang B,Long X,Wang X
Published figure using CD62L (L-Selectin) monoclonal antibody (Product # 25-0621-82) in Flow Cytometry
Fri Sep 24 00:00:00 EDT 2021
Evaluation of DNA-Launched Virus-Like Particle Vaccines in an Immune Competent Mouse Model of Chikungunya Virus Infection.
Vaccines
Rayner JO,Kim JH,Roberts RW,Wood RR,Fouty B,Solodushko V
25-0621-82 was used in Flow Cytometry to demonstrate the potential utility of DNA launched VLP vaccines in comparison to a live attenuated CHIKV vaccine and identify gender differences in viral RNA loads that impact interpretation of vaccine efficacy and may have important implications for future CHIKV vaccine development.
Fri Apr 02 00:00:00 EDT 2021
Evaluation of DNA-Launched Virus-Like Particle Vaccines in an Immune Competent Mouse Model of Chikungunya Virus Infection.
Vaccines
Rayner JO,Kim JH,Roberts RW,Wood RR,Fouty B,Solodushko V
25-0621-82 was used in Flow Cytometry to demonstrate the potential utility of DNA launched VLP vaccines in comparison to a live attenuated CHIKV vaccine and identify gender differences in viral RNA loads that impact interpretation of vaccine efficacy and may have important implications for future CHIKV vaccine development.
Fri Apr 02 00:00:00 EDT 2021
Aiduqing formula inhibits breast cancer metastasis by suppressing TAM/CXCL1-induced Treg differentiation and infiltration.
Cell communication and signaling : CCS
Li J,Wang S,Wang N,Zheng Y,Yang B,Wang X,Zhang J,Pan B,Wang Z
Published figure using CD62L (L-Selectin) monoclonal antibody (Product # 25-0621-82) in Immunocytochemistry
Mon Aug 30 00:00:00 EDT 2021
Aiduqing formula inhibits breast cancer metastasis by suppressing TAM/CXCL1-induced Treg differentiation and infiltration.
Cell communication and signaling : CCS
Li J,Wang S,Wang N,Zheng Y,Yang B,Wang X,Zhang J,Pan B,Wang Z
Published figure using CD62L (L-Selectin) monoclonal antibody (Product # 25-0621-82) in Immunocytochemistry
Mon Aug 30 00:00:00 EDT 2021
PI3Kδ coordinates transcriptional, chromatin, and metabolic changes to promote effector CD8+ T cells at the expense of central memory.
Cell reports
Cannons JL,Villarino AV,Kapnick SM,Preite S,Shih HY,Gomez-Rodriguez J,Kaul Z,Shibata H,Reilley JM,Huang B,Handon R,McBain IT,Gossa S,Wu T,Su HC,McGavern DB,O'Shea JJ,McGuire PJ,Uzel G,Schwartzberg PL
Published figure using CD62L (L-Selectin) monoclonal antibody (Product # 25-0621-82) in Flow Cytometry
Tue Oct 12 00:00:00 EDT 2021
Synchronous effects of targeted mitochondrial complex I inhibitors on tumor and immune cells abrogate melanoma progression.
iScience
AbuEid M,McAllister DM,McOlash L,Harwig MC,Cheng G,Drouillard D,Boyle KA,Hardy M,Zielonka J,Johnson BD,Hill RB,Kalyanaraman B,Dwinell MB
Published figure using CD62L (L-Selectin) monoclonal antibody (Product # 25-0621-82) in Flow Cytometry
Fri Jun 25 00:00:00 EDT 2021
Theranostic near-infrared-IIb emitting nanoprobes for promoting immunogenic radiotherapy and abscopal effects against cancer metastasis.
Nature communications
Li H,Wang M,Huang B,Zhu SW,Zhou JJ,Chen DR,Cui R,Zhang M,Sun ZJ
Published figure using CD62L (L-Selectin) monoclonal antibody (Product # 25-0621-82) in Flow Cytometry
Thu Dec 09 00:00:00 EST 2021
Targeting Phosphatidylserine Enhances the Anti-tumor Response to Tumor-Directed Radiation Therapy in a Preclinical Model of Melanoma.
Cell reports
Budhu S,Giese R,Gupta A,Fitzgerald K,Zappasodi R,Schad S,Hirschhorn D,Campesato LF,De Henau O,Gigoux M,Liu C,Mazo G,Deng L,Barker CA,Wolchok JD,Merghoub T
Published figure using CD62L (L-Selectin) monoclonal antibody (Product # 25-0621-82) in Flow Cytometry
Tue Jan 12 00:00:00 EST 2021
Type 1 Cytotoxic T Cells Increase in Placenta after Intrauterine Inflammation.
Frontiers in immunology
Liu J,Liu Y,Panda S,Liu A,Lei J,Burd I
Published figure using CD62L (L-Selectin) monoclonal antibody (Product # 25-0621-82) in Flow Cytometry
Fri Dec 17 00:00:00 EST 2021
Near-infrared photoimmunotherapy targeting human-EGFR in a mouse tumor model simulating current and future clinical trials.
EBioMedicine
Okada R,Furusawa A,Vermeer DW,Inagaki F,Wakiyama H,Kato T,Nagaya T,Choyke PL,Spanos WC,Allen CT,Kobayashi H
Published figure using CD62L (L-Selectin) monoclonal antibody (Product # 25-0621-82) in Flow Cytometry
Sat May 01 00:00:00 EDT 2021
Inhibition of TLR4 signaling protects mice from sensory and motor dysfunction in an animal model of autoimmune peripheral neuropathy.
Journal of neuroinflammation
Oladiran O,Shi XQ,Yang M,Fournier S,Zhang J
Published figure using CD62L (L-Selectin) monoclonal antibody (Product # 25-0621-82) in Flow Cytometry
Mon Mar 22 00:00:00 EDT 2021
STING Activated Tumor-Intrinsic Type I Interferon Signaling Promotes CXCR3 Dependent Antitumor Immunity in Pancreatic Cancer.
Cellular and molecular gastroenterology and hepatology
Vonderhaar EP,Barnekow NS,McAllister D,McOlash L,Eid MA,Riese MJ,Tarakanova VL,Johnson BD,Dwinell MB
Published figure using CD62L (L-Selectin) monoclonal antibody (Product # 25-0621-82) in Flow Cytometry
Mon Jan 24 00:00:00 EST 2022
A nanounit strategy reverses immune suppression of exosomal PD-L1 and is associated with enhanced ferroptosis.
Nature communications
Wang G,Xie L,Li B,Sang W,Yan J,Li J,Tian H,Li W,Zhang Z,Tian Y,Dai Y
Published figure using CD62L (L-Selectin) monoclonal antibody (Product # 25-0621-82) in Flow Cytometry
Thu Sep 30 00:00:00 EDT 2021
Graded RhoA GTPase Expression in Treg Cells Distinguishes Tumor Immunity From Autoimmunity.
Frontiers in immunology
Kalim KW,Yang JQ,Modur V,Nguyen P,Li Y,Zheng Y,Guo F
Published figure using CD62L (L-Selectin) monoclonal antibody (Product # 25-0621-82) in Flow Cytometry
Tue Jan 11 00:00:00 EST 2022
Mitochondrial transcription factor A in RORγt+ lymphocytes regulate small intestine homeostasis and metabolism.
Nature communications
Fu Z,Dean JW,Xiong L,Dougherty MW,Oliff KN,Chen ZE,Jobin C,Garrett TJ,Zhou L
25-0621-82 was used in Flow Cytometry to show that IL-22, a cytokine produced by RORγt+ lymphocytes inhibits IL-13-induced tuft cell differentiation in vitro, and suppresses the tuft cell-type 2 immune circuit and small intestine lengthening in vivo, highlighting its key role in gut tissue remodeling.
Thu Jul 22 00:00:00 EDT 2021
Mesenteric Lymph Node Transplantation in Mice to Study Immune Responses of the Gastrointestinal Tract.
Frontiers in immunology
Shaikh H,Vargas JG,Mokhtari Z,Jarick KJ,Ulbrich M,Mosca JP,Viera EA,Graf C,Le DD,Heinze KG,Büttner-Herold M,Rosenwald A,Pezoldt J,Huehn J,Beilhack A
25-0621-82 was used in Flow Cytometry to provide a protocol of syngeneic mesenteric lymph node (mLN) transplantation and report assays to analyse effective mLN engraftment in congenic mouse recipients.
Wed Oct 27 00:00:00 EDT 2021
Analysis of T cells in mouse lymphoid tissue and blood with flow cytometry.
STAR protocols
Skordos I,Demeyer A,Beyaert R
Published figure using CD62L (L-Selectin) monoclonal antibody (Product # 25-0621-82) in Flow Cytometry
Fri Mar 19 00:00:00 EDT 2021
A Hyper-IgM Syndrome Mutation in Activation-Induced Cytidine Deaminase Disrupts G-Quadruplex Binding and Genome-wide Chromatin Localization.
Immunity
Yewdell WT,Kim Y,Chowdhury P,Lau CM,Smolkin RM,Belcheva KT,Fernandez KC,Cols M,Yen WF,Vaidyanathan B,Angeletti D,McDermott AB,Yewdell JW,Sun JC,Chaudhuri J
25-0621-82 was used in Flow cytometry/Cell sorting to indicate a crucial role for G4 binding in AID targeting and suggest that AID activity may extend beyond Ig loci to regulate the expression of genes relevant to the physiology and pathology of activated B cells.
Tue Nov 17 00:00:00 EST 2020
MEF2D sustains activation of effector Foxp3+ Tregs during transplant survival and anticancer immunity.
The Journal of clinical investigation
Di Giorgio E,Wang L,Xiong Y,Akimova T,Christensen LM,Han R,Samanta A,Trevisanut M,Bhatti TR,Beier UH,Hancock WW
25-0621 was used in Flow cytometry/Cell sorting to study the role played by MEF2D in sustaining effector Foxp3+ Treg functions without abrogating their basal actions suggests its suitability for drug discovery efforts in cancer therapy.
Tue Dec 01 00:00:00 EST 2020
B Cell Diversification Is Uncoupled from SAP-Mediated Selection Forces in Chronic Germinal Centers within Peyer's Patches.
Cell reports
Biram A,Winter E,Denton AE,Zaretsky I,Dassa B,Bemark M,Linterman MA,Yaari G,Shulman Z
Published figure using CD62L (L-Selectin) monoclonal antibody (Product # 25-0621-82) in Flow Cytometry
Tue Feb 11 00:00:00 EST 2020
Attenuation of TCR-induced transcription by Bach2 controls regulatory T cell differentiation and homeostasis.
Nature communications
Sidwell T,Liao Y,Garnham AL,Vasanthakumar A,Gloury R,Blume J,Teh PP,Chisanga D,Thelemann C,de Labastida Rivera F,Engwerda CR,Corcoran L,Kometani K,Kurosaki T,Smyth GK,Shi W,Kallies A
25-0621 was used in Flow cytometry/Cell sorting to show homeostasis of thymically-derived and peripherally-derived Treg cells is maintained through the balancing of TCR signaling induced transcriptional activity by Bach2.
Tue Jan 14 00:00:00 EST 2020
PTPN2 Deficiency Enhances Programmed T Cell Expansion and Survival Capacity of Activated T Cells.
Cell reports
Flosbach M,Oberle SG,Scherer S,Zecha J,von Hoesslin M,Wiede F,Chennupati V,Cullen JG,List M,Pauling JK,Baumbach J,Kuster B,Tiganis T,Zehn D
25-0621 was used in Flow cytometry/Cell sorting to show the therapeutic potential of targeting PTPN2 in T cell-based therapies to augment the number and survival capacity of antigen-specific T cells.
Tue Jul 28 00:00:00 EDT 2020
Ovarian granulosa cell tumor characterization identifies FOXL2 as an immunotherapeutic target.
JCI insight
Pierini S,Tanyi JL,Simpkins F,George E,Uribe-Herranz M,Drapkin R,Burger R,Morgan MA,Facciabene A
25-0621 was used in Flow cytometry/Cell sorting to study can serve as a foundation for trials testing immunotherapeutic approaches in patients with ovarian GCT.
Thu Aug 20 00:00:00 EDT 2020
Localized cocktail chemoimmunotherapy after in situ gelation to trigger robust systemic antitumor immune responses.
Science advances
Chao Y,Liang C,Tao H,Du Y,Wu D,Dong Z,Jin Q,Chen G,Xu J,Xiao Z,Chen Q,Wang C,Chen J,Liu Z
Published figure using CD62L (L-Selectin) monoclonal antibody (Product # 25-0621-82) in Flow Cytometry
Sun Mar 01 00:00:00 EST 2020
SLAMF6 deficiency augments tumor killing and skews toward an effector phenotype revealing it as a novel T cell checkpoint.
eLife
Hajaj E,Eisenberg G,Klein S,Frankenburg S,Merims S,Ben David I,Eisenhaure T,Henrickson SE,Villani AC,Hacohen N,Abudi N,Abramovich R,Cohen JE,Peretz T,Veillette A,Lotem M
25-0621-82 was used in Flow Cytometry to support the notion that SLAMF6 is an inhibitory immune receptor whose absence enables powerful CD8+ T cells to eradicate tumors.
Tue Mar 03 00:00:00 EST 2020
Cyclooxygenase-1 Regulates the Development of Follicular Th Cells via Prostaglandin E2.
Journal of immunology (Baltimore, Md. : 1950)
Liu T,Yang Q,Cao YJ,Yuan WM,Lei AH,Zhou P,Zhou W,Liu YD,Shi MH,Yang Q,Tang JY,Wang HK,Zhang H,Yu Y,Zhou J
25-0621-82 was used in Flow Cytometry to indicate that COX-1 plays an important role in the development of TFH cells.
Thu Aug 15 00:00:00 EDT 2019
ER stress-induced mediator C/EBP homologous protein thwarts effector T cell activity in tumors through T-bet repression.
Nature communications
Cao Y,Trillo-Tinoco J,Sierra RA,Anadon C,Dai W,Mohamed E,Cen L,Costich TL,Magliocco A,Marchion D,Klar R,Michel S,Jaschinski F,Reich RR,Mehrotra S,Cubillos-Ruiz JR,Munn DH,Conejo-Garcia JR,Rodriguez PC
Published figure using CD62L (L-Selectin) monoclonal antibody (Product # 25-0621-82) in Flow Cytometry
Wed Mar 20 00:00:00 EDT 2019
Pulsatile MEK Inhibition Improves Anti-tumor Immunity and T Cell Function in Murine Kras Mutant Lung Cancer.
Cell reports
Choi H,Deng J,Li S,Silk T,Dong L,Brea EJ,Houghton S,Redmond D,Zhong H,Boiarsky J,Akbay EA,Smith PD,Merghoub T,Wong KK,Wolchok JD
Published figure using CD62L (L-Selectin) monoclonal antibody (Product # 25-0621-82) in Flow Cytometry
Tue Apr 16 00:00:00 EDT 2019
Activated Peyer's patch B cells sample antigen directly from M cells in the subepithelial dome.
Nature communications
Komban RJ,Strömberg A,Biram A,Cervin J,Lebrero-Fernández C,Mabbott N,Yrlid U,Shulman Z,Bemark M,Lycke N
Published figure using CD62L (L-Selectin) monoclonal antibody (Product # 25-0621-82) in Flow Cytometry
Mon Jun 03 00:00:00 EDT 2019
A functional subset of CD8+ T cells during chronic exhaustion is defined by SIRPα expression.
Nature communications
Myers LM,Tal MC,Torrez Dulgeroff LB,Carmody AB,Messer RJ,Gulati G,Yiu YY,Staron MM,Angel CL,Sinha R,Markovic M,Pham EA,Fram B,Ahmed A,Newman AM,Glenn JS,Davis MM,Kaech SM,Weissman IL,Hasenkrug KJ
25-0621-82 was used in Flow Cytometry to demonstrate that even during exhaustion there is a subset of functional CD8+ T cells defined by surface expression of SIRPα.
Fri Feb 15 00:00:00 EST 2019
Sex Differences in Mouse Popliteal Lymph Nodes.
Scientific reports
Dill-Garlow R,Chen KE,Walker AM
25-0621 was used in Flow cytometry/Cell sorting to investigate the underlying sex differences that may contribute to differential footpad delayed-type hypersensitivity responses using wildtype and four core genotypes mice and popliteal lymphnode cellularity and gene expression.
Wed Jan 30 00:00:00 EST 2019
A chemical biology toolbox to study protein methyltransferases and epigenetic signaling.
Nature communications
Scheer S,Ackloo S,Medina TS,Schapira M,Li F,Ward JA,Lewis AM,Northrop JP,Richardson PL,Kaniskan HÜ,Shen Y,Liu J,Smil D,McLeod D,Zepeda-Velazquez CA,Luo M,Jin J,Barsyte-Lovejoy D,Huber KVM,De Carvalho DD,Vedadi M,Zaph C,Brown PJ,Arrowsmith CH
25-0621 was used in Flow cytometry/Cell sorting to present a collection of chemical probes and associated reagents and data to elucidate the function of human and murine protein methyltransferases in cellular studies.
Thu Jan 03 00:00:00 EST 2019
The Inhibitory T Cell Receptors PD1 and 2B4 Are Differentially Regulated on CD4 and CD8 T Cells in a Mouse Model of Non-alcoholic Steatohepatitis.
Frontiers in pharmacology
Hansel C,Erschfeld S,Baues M,Lammers T,Weiskirchen R,Trautwein C,Kroy DC,Drescher HK
25-0621 was used in Flow cytometry/Cell sorting to investigate the expression profile of inhibitory T cell receptors on CD4 and CD8 T cells in a mouse model of non-alcoholic steatohepatitis.
Wed Sep 30 00:00:00 EDT 2020
MTOR signaling is essential for the development of thymic epithelial cells and the induction of central immune tolerance.
Autophagy
Liang Z,Zhang L,Su H,Luan R,Na N,Sun L,Zhao Y,Zhang X,Zhang Q,Li J,Zhang L,Zhao Y
Published figure using CD62L (L-Selectin) monoclonal antibody (Product # 25-0621-82) in Flow Cytometry
Fri Mar 22 00:00:00 EDT 2019
De Novo Fatty Acid Synthesis During Mycobacterial Infection Is a Prerequisite for the Function of Highly Proliferative T Cells, But Not for Dendritic Cells or Macrophages.
Frontiers in immunology
Stüve P,Minarrieta L,Erdmann H,Arnold-Schrauf C,Swallow M,Guderian M,Krull F,Hölscher A,Ghorbani P,Behrends J,Abraham WR,Hölscher C,Sparwasser TD,Berod L
25-0621-82 was used in Flow Cytometry to reveal that acetyl-CoA carboxylase 1-dependent fatty acid synthesis is a crucial mechanism in T cells, but not dendritic cells or macrophages, to fight against mycobacterial infection.
Wed Apr 10 00:00:00 EDT 2019
C5aR1 regulates T follicular helper differentiation and chronic graft-versus-host disease bronchiolitis obliterans.
JCI insight
Verghese DA,Chun N,Paz K,Fribourg M,Woodruff TM,Flynn R,Hu Y,Xiong H,Zhang W,Yi Z,Du J,Blazar BR,Heeger PS
Published figure using CD62L (L-Selectin) monoclonal antibody (Product # 25-0621-82) in Flow Cytometry
Thu Dec 20 00:00:00 EST 2018
Helminth-induced IL-4 expands bystander memory CD8+ T cells for early control of viral infection.
Nature communications
Rolot M,Dougall AM,Chetty A,Javaux J,Chen T,Xiao X,Machiels B,Selkirk ME,Maizels RM,Hokke C,Denis O,Brombacher F,Vanderplasschen A,Gillet L,Horsnell WGC,Dewals BG
Published figure using CD62L (L-Selectin) monoclonal antibody (Product # 25-0621-82) in Flow Cytometry
Tue Oct 30 00:00:00 EDT 2018
The immunocytokine L19-IL2: An interplay between radiotherapy and long-lasting systemic anti-tumour immune responses.
Oncoimmunology
Rekers NH,Olivo Pimentel V,Yaromina A,Lieuwes NG,Biemans R,Zegers CML,Germeraad WTV,Van Limbergen EJ,Neri D,Dubois LJ,Lambin P
25-0621 was used in Flow cytometry/Cell sorting to show that radiotherapy and L19-IL2 can activate a curative abscopal effect, with a long-lasting immunological memory.
Tue Jan 12 00:00:00 EST 2021
Stability and function of regulatory T cells expressing the transcription factor T-bet.
Nature
Levine AG,Mendoza A,Hemmers S,Moltedo B,Niec RE,Schizas M,Hoyos BE,Putintseva EV,Chaudhry A,Dikiy S,Fujisawa S,Chudakov DM,Treuting PM,Rudensky AY
Published figure using CD62L (L-Selectin) monoclonal antibody (Product # 25-0621-82) in Flow Cytometry
Thu Jun 15 00:00:00 EDT 2017
Antibody Tumor Targeting Is Enhanced by CD27 Agonists through Myeloid Recruitment.
Cancer cell
Turaj AH,Hussain K,Cox KL,Rose-Zerilli MJJ,Testa J,Dahal LN,Chan HTC,James S,Field VL,Carter MJ,Kim HJ,West JJ,Thomas LJ,He LZ,Keler T,Johnson PWM,Al-Shamkhani A,Thirdborough SM,Beers SA,Cragg MS,Glennie MJ,Lim SH
Published figure using CD62L (L-Selectin) monoclonal antibody (Product # 25-0621-82) in Flow Cytometry
Mon Dec 11 00:00:00 EST 2017
Excessive expression of miR-27 impairs Treg-mediated immunological tolerance.
The Journal of clinical investigation
Cruz LO,Hashemifar SS,Wu CJ,Cho S,Nguyen DT,Lin LL,Khan AA,Lu LF
Published figure using CD62L (L-Selectin) monoclonal antibody (Product # 25-0621-82) in Flow Cytometry
Wed Feb 01 00:00:00 EST 2017
Egr2 and 3 control adaptive immune responses by temporally uncoupling expansion from T cell differentiation.
The Journal of experimental medicine
Miao T,Symonds ALJ,Singh R,Symonds JD,Ogbe A,Omodho B,Zhu B,Li S,Wang P
Published figure using CD62L (L-Selectin) monoclonal antibody (Product # 25-0621-82) in Flow Cytometry
Mon Jun 05 00:00:00 EDT 2017
Culling of APCs by inflammatory cell death pathways restricts TIM3 and PD-1 expression and promotes the survival of primed CD8 T cells.
Cell death and differentiation
Patel R,Kim K,Shutinoski B,Wachholz K,Krishnan L,Sad S
25-0621 was used in Flow cytometry/Cell sorting to evaluate the impact of premature cell death of antigen-presenting cells by Caspase-1- and RipK3-signalling pathways on CD8+ T-cell priming during infection of mice with Salmonella typhimurium.
Wed Nov 01 00:00:00 EDT 2017
Peripheral administration of the soluble TNF inhibitor XPro1595 modifies brain immune cell profiles, decreases beta-amyloid plaque load, and rescues impaired long-term potentiation in 5xFAD mice.
Neurobiology of disease
MacPherson KP,Sompol P,Kannarkat GT,Chang J,Sniffen L,Wildner ME,Norris CM,Tansey MG
25-0621 was used in Flow cytometry/Cell sorting to assess the translational potential of soluble TNF inhibitors to modulate brain immune cell infiltration, dampen neuroinflammation and prevent or delay neuronal dysfunction in Alzheimer's disease.
Thu Jun 01 00:00:00 EDT 2017
Toll like Receptor 2 engagement on CD4+ T cells promotes TH9 differentiation and function.
European journal of immunology
Karim AF,Reba SM,Li Q,Boom WH,Rojas RE
25-0621 was used in Flow cytometry/Cell sorting to study the role of T-cell expressed TLR2 on CD4+ T-cell differentiation and function.
Fri Sep 01 00:00:00 EDT 2017
Differential Inhibitory Receptor Expression on T Cells Delineates Functional Capacities in Chronic Viral Infection.
Journal of virology
Teigler JE,Zelinskyy G,Eller MA,Bolton DL,Marovich M,Gordon AD,Alrubayyi A,Alter G,Robb ML,Martin JN,Deeks SG,Michael NL,Dittmer U,Streeck H
25-0621 was used in Flow cytometry/Cell sorting to determine and compare inhibitory receptor expression patterns on virus-specific CD4 and CD8 T cells in relation to their functional T cell profile.
Fri Dec 01 00:00:00 EST 2017
The Ox40/Ox40 Ligand Pathway Promotes Pathogenic Th Cell Responses, Plasmablast Accumulation, and Lupus Nephritis in NZB/W F1 Mice.
Journal of immunology (Baltimore, Md. : 1950)
Sitrin J,Suto E,Wuster A,Eastham-Anderson J,Kim JM,Austin CD,Lee WP,Behrens TW
Published figure using CD62L (L-Selectin) monoclonal antibody (Product # 25-0621-82) in Flow Cytometry
Tue Aug 15 00:00:00 EDT 2017
Batf3-dependent CD8α+ Dendritic Cells Aggravates Atherosclerosis via Th1 Cell Induction and Enhanced CCL5 Expression in Plaque Macrophages.
EBioMedicine
Li Y,Liu X,Duan W,Tian H,Zhu G,He H,Yao S,Yi S,Song W,Tang H
Published figure using CD62L (L-Selectin) monoclonal antibody (Product # 25-0621-82) in Flow Cytometry
Sat Apr 01 00:00:00 EDT 2017
Extrafollicular CD4+ T-B interactions are sufficient for inducing autoimmune-like chronic graft-versus-host disease.
Nature communications
Deng R,Hurtz C,Song Q,Yue C,Xiao G,Yu H,Wu X,Muschen M,Forman S,Martin PJ,Zeng D
Published figure using CD62L (L-Selectin) monoclonal antibody (Product # 25-0621-82) in Flow Cytometry
Tue Oct 17 00:00:00 EDT 2017
The somatically generated portion of T cell receptor CDR3α contributes to the MHC allele specificity of the T cell receptor.
eLife
Marrack P,Krovi SH,Silberman D,White J,Kushnir E,Nakayama M,Crooks J,Danhorn T,Leach S,Anselment R,Scott-Browne J,Gapin L,Kappler J
25-0621-82 was used in Flow Cytometry to study how the positive selection-induced major histocompatibility complex protein bias of T cell receptors is affected by both germline and non-germline elements.
Fri Nov 17 00:00:00 EST 2017
The cryo-thermal therapy eradicated melanoma in mice by eliciting CD4+ T-cell-mediated antitumor memory immune response.
Cell death & disease
He K,Liu P,Xu LX
25-0621 was used in Flow cytometry/Cell sorting to demonstrate the therapeutic efficacy in other aggressive tumor models and further investigate the mechanism of long-term survival induced.
Thu Mar 23 00:00:00 EDT 2017
Metabolic maintenance of cell asymmetry following division in activated T lymphocytes.
Nature
Verbist KC,Guy CS,Milasta S,Liedmann S,Kamiński MM,Wang R,Green DR
25-0621 was used in Flow cytometry/Cell sorting to investigate the mechanisms that sustain differential cell fates in daughter T cells after activation by an antigen-presenting cell.
Thu Apr 21 00:00:00 EDT 2016
Blood pressure regulation by CD4+ lymphocytes expressing choline acetyltransferase.
Nature biotechnology
Olofsson PS,Steinberg BE,Sobbi R,Cox MA,Ahmed MN,Oswald M,Szekeres F,Hanes WM,Introini A,Liu SF,Holodick NE,Rothstein TL,Lövdahl C,Chavan SS,Yang H,Pavlov VA,Broliden K,Andersson U,Diamond B,Miller EJ,Arner A,Gregersen PK,Backx PH,Mak TW,Tracey KJ
25062182 was used in flow cytometry to elucidate how CD4 positive T cells help regulate blood pressure
Sat Oct 01 00:00:00 EDT 2016
NKT sublineage specification and survival requires the ubiquitin-modifying enzyme TNFAIP3/A20.
The Journal of experimental medicine
Drennan MB,Govindarajan S,Verheugen E,Coquet JM,Staal J,McGuire C,Taghon T,Leclercq G,Beyaert R,van Loo G,Lambrecht BN,Elewaut D
25-0621 was used in Flow cytometry/Cell sorting to show that negative regulation of TCR signalling during NKT development controls the differentiation and survival of NKT1 and NKT2 cells.
Mon Sep 19 00:00:00 EDT 2016
CD4 T Helper Cells Instruct Lymphopenia-Induced Memory-Like CD8 T Cells for Control of Acute LCMV Infection.
Frontiers in immunology
Schmitt ME,Sitte S,Voehringer D
25-0621 was used in Flow cytometry/Cell sorting to determine whether memory-like T cells can efficiently respond to foreign antigen and participate in antiviral immunity.
Wed Nov 20 00:00:00 EST 2019
IL-12 and IL-4 activate a CD39-dependent intrinsic peripheral tolerance mechanism in CD8(+) T cells.
European journal of immunology
Noble A,Mehta H,Lovell A,Papaioannou E,Fairbanks L
25-0621 was used in Flow cytometry/Cell sorting to study the upregulation of CD39 on CD8(+) T cells and identify a novel pathway of peripheral tolerance.
Wed Jun 01 00:00:00 EDT 2016
Dendritic Cells Are Dispensable for T Cell Priming and Control of Acute Lymphocytic Choriomeningitis Virus Infection.
Journal of immunology (Baltimore, Md. : 1950)
Hilpert C,Sitte S,Matthies A,Voehringer D
25-0621 was used in Flow cytometry/Cell sorting to study the role of dendritic cells as antigen presenting cells and a source of type I interferons in acute lymphocytic choriomeningitis virus infection.
Sat Oct 01 00:00:00 EDT 2016
Premature thymic involution is independent of structural plasticity of the thymic stroma.
European journal of immunology
Franckaert D,Schlenner SM,Heirman N,Gill J,Skogberg G,Ekwall O,Put K,Linterman MA,Dooley J,Liston A
25-0621 was used in Flow cytometry/Cell sorting to investigate thymic involution in FVB/N mice, showing that disruption of the epithelial-endothelial relationship and a progressive loss of pro-T cells precedes involution, and loss of pro-T cells is sufficient to drive premature involution, suggesting that pro-T cells are the main driver of involution.
Fri May 01 00:00:00 EDT 2015
Promiscuous Foxp3-cre activity reveals a differential requirement for CD28 in Foxp3⁺ and Foxp3⁻ T cells.
Immunology and cell biology
Franckaert D,Dooley J,Roos E,Floess S,Huehn J,Luche H,Fehling HJ,Liston A,Linterman MA,Schlenner SM
25-0621 was used in Flow cytometry/Cell sorting to investigate the functional requirement for CD28 during peripheral regulatory T cell post thymic selection.
Wed Apr 01 00:00:00 EDT 2015
Unexpected Role for Adaptive αβTh17 Cells in Acute Respiratory Distress Syndrome.
Journal of immunology (Baltimore, Md. : 1950)
Li JT,Melton AC,Su G,Hamm DE,LaFemina M,Howard J,Fang X,Bhat S,Huynh KM,O'Kane CM,Ingram RJ,Muir RR,McAuley DF,Matthay MA,Sheppard D
Published figure using CD62L (L-Selectin) monoclonal antibody (Product # 25-0621-82) in Flow Cytometry
Wed Jul 01 00:00:00 EDT 2015
Continuous Antigenic Stimulation of DO11.10 TCR Transgenic Mice in the Presence or Absence of IL-1β: Possible Implications for Mechanisms of T Cell Depletion in HIV Disease.
Journal of immunology (Baltimore, Md. : 1950)
Ladell K,Hazenberg MD,Fitch M,Emson C,McEvoy-Hein Asgarian BK,Mold JE,Miller C,Busch R,Price DA,Hellerstein MK,McCune JM
25-0621 was used in Flow cytometry/Cell sorting to partially implicate chronic Ag exposure for the depleted adaptive immune response observed in HIV patients.
Sun Nov 01 00:00:00 EDT 2015
Targeted Mutation of Nuclear Bone Morphogenetic Protein 2 Impairs Secondary Immune Response in a Mouse Model.
BioMed research international
Olsen DS,Goar WA,Nichols BA,Bailey KT,Christensen SL,Merriam KR,Reynolds PR,Wilson E,Weber KS,Bridgewater LC
Published figure using CD62L (L-Selectin) monoclonal antibody (Product # 25-0621-82) in Flow Cytometry
Mon Aug 01 00:00:00 EDT 2016
Lymph node stromal cells constrain immunity via MHC class II self-antigen presentation.
eLife
Baptista AP,Roozendaal R,Reijmers RM,Koning JJ,Unger WW,Greuter M,Keuning ED,Molenaar R,Goverse G,Sneeboer MM,den Haan JM,Boes M,Mebius RE
25-0621 was used in Flow cytometry/Cell sorting to investigate the role of MHC-II in lymph node stromal cells, showing that stromal cells constrain immunity through MHC-II expression.
Wed Nov 19 00:00:00 EST 2014
TLR2 engagement on CD4(+) T cells enhances effector functions and protective responses to Mycobacterium tuberculosis.
European journal of immunology
Reba SM,Li Q,Onwuzulike S,Ding X,Karim AF,Hernandez Y,Fulton SA,Harding CV,Lancioni CL,Nagy N,Rodriguez ME,Wearsch PA,Rojas RE
25-0621-82 was used in Flow cytometry/Cell sorting to examine the role of CD4(+) T-cell-expressed TLR2 in Mycobacterium tuberculosis (MTB) Ag-specific T-cell priming and in protection against MTB infection in vivo.
Thu May 01 00:00:00 EDT 2014
Prophylaxis with a respiratory syncytial virus (RSV) anti-G protein monoclonal antibody shifts the adaptive immune response to RSV rA2-line19F infection from Th2 to Th1 in BALB/c mice.
Journal of virology
Boyoglu-Barnum S,Chirkova T,Todd SO,Barnum TR,Gaston KA,Jorquera P,Haynes LM,Tripp RA,Moore ML,Anderson LJ
25-0621 was used in Flow cytometry/Cell sorting to suggest that the RSV G protein not only contributes to disease, but also dampens the host immune response to infection.
Mon Sep 01 00:00:00 EDT 2014
Myelin-specific T helper 17 cells promote adult hippocampal neurogenesis through indirect mechanisms.
F1000Research
Niebling J,E Rünker A,Schallenberg S,Kretschmer K,Kempermann G
Published figure using CD62L (L-Selectin) monoclonal antibody (Product # 25-0621-82) in Flow Cytometry
Fri Mar 06 00:00:00 EST 2020
STAT4 is required for IL-23 responsiveness in Th17 memory cells and NKT cells.
JAK-STAT
Glosson-Byers NL,Sehra S,Kaplan MH
Published figure using CD62L (L-Selectin) monoclonal antibody (Product # 25-0621-82) in Flow Cytometry
Mon Sep 28 00:00:00 EDT 2015
Autophagy is a critical regulator of memory CD8(+) T cell formation.
eLife
Puleston DJ,Zhang H,Powell TJ,Lipina E,Sims S,Panse I,Watson AS,Cerundolo V,Townsend AR,Klenerman P,Simon AK
25-0621 was used in Flow cytometry/Cell sorting to show that mice lacking the autophagy gene Atg7 in T cells failed to establish CD8(+) T cell memory to influenza and MCMV infection.
Tue Nov 11 00:00:00 EST 2014
Antiapoptotic Mcl-1 is critical for the survival and niche-filling capacity of Foxp3⁺ regulatory T cells.
Nature immunology
Pierson W,Cauwe B,Policheni A,Schlenner SM,Franckaert D,Berges J,Humblet-Baron S,Schönefeldt S,Herold MJ,Hildeman D,Strasser A,Bouillet P,Lu LF,Matthys P,Freitas AA,Luther RJ,Weaver CT,Dooley J,Gray DH,Liston A
25-0621 was used in Flow cytometry/Cell sorting to study the regulation of the Foxp3+ T cell pool by proliferation and apoptosis, and specifically the role of antiapoptoic Mcl-1 in T cell survival.
Sun Sep 01 00:00:00 EDT 2013
A disease-associated PTPN22 variant promotes systemic autoimmunity in murine models.
The Journal of clinical investigation
Dai X,James RG,Habib T,Singh S,Jackson S,Khim S,Moon RT,Liggitt D,Wolf-Yadlin A,Buckner JH,Rawlings DJ
Published figure using CD62L (L-Selectin) monoclonal antibody (Product # 25-0621-82) in Flow Cytometry
Wed May 01 00:00:00 EDT 2013
IL-21 is a double-edged sword in the systemic lupus erythematosus-like disease of BXSB.Yaa mice.
Journal of immunology (Baltimore, Md. : 1950)
McPhee CG,Bubier JA,Sproule TJ,Park G,Steinbuck MP,Schott WH,Christianson GJ,Morse HC,Roopenian DC
25-0621 was used in Flow cytometry/Cell sorting to indicate that IL-21 has both disease-promoting and disease-suppressive effects in the autoimmune disease of BXSB.Yaa mice.
Fri Nov 01 00:00:00 EDT 2013
Prolonged apoptotic cell accumulation in germinal centers of Mer-deficient mice causes elevated B cell and CD4+ Th cell responses leading to autoantibody production.
Journal of immunology (Baltimore, Md. : 1950)
Khan TN,Wong EB,Soni C,Rahman ZS
25-0621 was used in Flow cytometry/Cell sorting to study the effect of Mer receptor tyrosine kinase deficiency on the clearance of apoptotic cells.
Fri Feb 15 00:00:00 EST 2013
Loss of T cell microRNA provides systemic protection against autoimmune pathology in mice.
Journal of autoimmunity
Tian L,De Hertogh G,Fedeli M,Staats KA,Schonefeldt S,Humblet-Baron S,Van Den Bosch L,Dellabona P,Dooley J,Liston A
25-0621 was used in Flow cytometry/Cell sorting to elucidate the dominant effects of the T cell microRNA expression network and explore it as a potential therapeutic target for autoimmune diseases.
Wed Feb 01 00:00:00 EST 2012
IL-10 limits parasite burden and protects against fatal myocarditis in a mouse model of Trypanosoma cruzi infection.
Journal of immunology (Baltimore, Md. : 1950)
Roffê E,Rothfuchs AG,Santiago HC,Marino AP,Ribeiro-Gomes FL,Eckhaus M,Antonelli LR,Murphy PM
25-0621 was used in Flow cytometry/Cell sorting to investigate the mechanism by which IL-10 protects against fatal myocarditis in a mouse model of Trypanosoma cruzi infection.
Sun Jan 15 00:00:00 EST 2012
Hepatocyte-specific S100a8 and S100a9 transgene expression in mice causes Cxcl1 induction and systemic neutrophil enrichment.
Cell communication and signaling : CCS
Wiechert L,Németh J,Pusterla T,Bauer C,De Ponti A,Manthey S,Marhenke S,Vogel A,Klingmüller U,Hess J,Angel P
Published figure using CD62L (L-Selectin) monoclonal antibody (Product # 25-0621-82) in Flow Cytometry
Sat Dec 15 00:00:00 EST 2012
The transcriptional regulators Id2 and Id3 control the formation of distinct memory CD8+ T cell subsets.
Nature immunology
Yang CY,Best JA,Knell J,Yang E,Sheridan AD,Jesionek AK,Li HS,Rivera RR,Lind KC,D'Cruz LM,Watowich SS,Murre C,Goldrath AW
25-0621 was used in Flow cytometry/Cell sorting to elucidate the mechanisms of regulation of terminal differentiation of CD8(+) T cells.
Sun Nov 06 00:00:00 EDT 2011
CCR3 Blockade Attenuates Eosinophilic Ileitis and Associated Remodeling.
The American journal of pathology
Masterson JC,McNamee EN,Jedlicka P,Fillon S,Ruybal J,Hosford L,Rivera-Nieves J,Lee JJ,Furuta GT
25-0621 was used in Flow cytometry/Cell sorting to demonstrate an association between ileitis progression and remodeling over the course of 40 weeks.
Tue Nov 01 00:00:00 EDT 2011
MHC class I family proteins retard systemic lupus erythematosus autoimmunity and B cell lymphomagenesis.
Journal of immunology (Baltimore, Md. : 1950)
McPhee CG,Sproule TJ,Shin DM,Bubier JA,Schott WH,Steinbuck MP,Avenesyan L,Morse HC,Roopenian DC
25-0621 was used in Flow cytometry/Cell sorting to investigate the extent to which processes controlled by MHC class I proteins impact autoimmune and neoplastic disorders.
Tue Nov 01 00:00:00 EDT 2011
Graft-versus-host disease is independent of innate signaling pathways triggered by pathogens in host hematopoietic cells.
Journal of immunology (Baltimore, Md. : 1950)
Li H,Matte-Martone C,Tan HS,Venkatesan S,McNiff J,Demetris AJ,Jain D,Lakkis F,Rothstein D,Shlomchik WD
25-0621 was used in Flow cytometry to investigate antigen-presenting cell activation in graft-versus-host disease.
Sat Jan 01 00:00:00 EST 2011
Role for MyD88, TLR2 and TLR9 but not TLR1, TLR4 or TLR6 in experimental autoimmune encephalomyelitis.
Journal of immunology (Baltimore, Md. : 1950)
Miranda-Hernandez S,Gerlach N,Fletcher JM,Biros E,Mack M,Körner H,Baxter AG
25-0621 was used in Flow cytometry/Cell sorting to examine the effects of targeted deletions of specific TLRs on the induction of toxin-induced autoimmune encephalomyelitis.
Fri Jul 15 00:00:00 EDT 2011
Modeling Sjögren's syndrome with Id3 conditional knockout mice.
Immunology letters
Guo Z,Li H,Han M,Xu T,Wu X,Zhuang Y
Published figure using CD62L (L-Selectin) monoclonal antibody (Product # 25-0621-82) in Flow Cytometry
Wed Mar 30 00:00:00 EDT 2011
IL-7 promotes T cell viability, trafficking, and functionality and improves survival in sepsis.
Journal of immunology (Baltimore, Md. : 1950)
Unsinger J,McGlynn M,Kasten KR,Hoekzema AS,Watanabe E,Muenzer JT,McDonough JS,Tschoep J,Ferguson TA,McDunn JE,Morre M,Hildeman DA,Caldwell CC,Hotchkiss RS
Published figure using CD62L (L-Selectin) monoclonal antibody (Product # 25-0621-82) in Flow Cytometry
Thu Apr 01 00:00:00 EDT 2010
Mycobacterium tuberculosis cell wall glycolipids directly inhibit CD4+ T-cell activation by interfering with proximal T-cell-receptor signaling.
Infection and immunity
Mahon RN,Rojas RE,Fulton SA,Franko JL,Harding CV,Boom WH
25-0621 was used in Flow cytometry/Cell sorting to investigate whether M. tuberculosis could directly inhibit CD4(+) T-cell activation.
Thu Oct 01 00:00:00 EDT 2009
Dicer-dependent microRNA pathway safeguards regulatory T cell function.
The Journal of experimental medicine
Liston A,Lu LF,O'Carroll D,Tarakhovsky A,Rudensky AY
25-0621 was used in Flow cytometry/Cell sorting to study regulatory T cell-mediated tolerance, showing that it is dependent on the Dicer-controlled microRNA pathway.
Mon Sep 01 00:00:00 EDT 2008
Activated CD8 T cells redistribute to antigen-free lymph nodes and exhibit effector and memory characteristics.
Journal of immunology (Baltimore, Md. : 1950)
Brinkman CC,Sheasley-O'Neill SL,Ferguson AR,Engelhard VH
25-0621 was used in Flow cytometry/Cell sorting to characterise the activation and differentiation of CD8 T cells in individual lymphoid compartments over time, and their migration between compartments.
Fri Aug 01 00:00:00 EDT 2008
The surprising kinetics of the T cell response to live antigenic cells.
Journal of immunology (Baltimore, Md. : 1950)
Tyznik AJ,Bevan MJ
25-0621 was used in Flow cytometry/Cell sorting to demonstrate dramatic differences in host T cell responses to noninflammatory Ags compared with responses to pathogens.
Mon Oct 15 00:00:00 EDT 2007
Modulation of naive CD4+ T-cell responses to an airway antigen during pulmonary mycobacterial infection.
Infection and immunity
Anis MM,Fulton SA,Reba SM,Harding CV,Boom WH
25-0621 was used in Flow cytometry/Cell sorting to demonstrate that infection alters lung DCs for activation of antigen-specific lung T cells in response to airway antigen challenge.
Tue May 01 00:00:00 EDT 2007
Toll-like receptor 2 regulates CXC chemokine production and neutrophil recruitment to the cornea in Onchocerca volvulus/Wolbachia-induced keratitis.
Infection and immunity
Gillette-Ferguson I,Daehnel K,Hise AG,Sun Y,Carlson E,Diaconu E,McGarry HF,Taylor MJ,Pearlman E
25-0621 was used in Flow cytometry/Cell sorting to determine the role of Toll-like receptors in neutrophil recruitment and activation.
Sat Dec 01 00:00:00 EST 2007
Cytosolic entry controls CD8+-T-cell potency during bacterial infection.
Infection and immunity
Bahjat KS,Liu W,Lemmens EE,Schoenberger SP,Portnoy DA,Dubensky TW,Brockstedt DG
25-0621 was used in Flow cytometry/Cell sorting to investigate microbial invasion of the cytosol as a key factor in inducing CD8+- T cell-mediated protection against L.monocytogenes.
Wed Nov 01 00:00:00 EST 2006
