Product References
Fasudil-modified macrophages reduce inflammation and regulate the immune response in experimental autoimmune encephalomyelitis.
Neural regeneration research
Liu C,Guo S,Liu R,Guo M,Wang Q,Chai Z,Xiao B,Ma C
Published figure using CD40 monoclonal antibody (Product # 16-0401-82) in Flow Cytometry
Fri Mar 01 00:00:00 EST 2024
Germinal center expansion but not plasmablast differentiation is proportional to peptide-MHCII density via CD40-CD40L signaling strength.
Cell reports
Jing Z,McCarron MJ,Dustin ML,Fooksman DR
16-0401-82 was used in Functional assays to establish a caged OVA peptide, which is readily detected by OVA-specific TFH cells after photo-uncaging.
Tue May 03 00:00:00 EDT 2022
Prostaglandin E2 serves a dual role in regulating the migration of dendritic cells.
International journal of molecular medicine
Diao G,Huang J,Zheng X,Sun X,Tian M,Han J,Guo J
Published figure using CD40 monoclonal antibody (Product # 16-0401-82) in Flow Cytometry
Fri Jan 01 00:00:00 EST 2021
Myeloid and plasmacytoid dendritic cell combined vaccines loaded with heat-treated tumor cell lysates enhance antitumor activity in murine lung cancer.
Oncology letters
Chen H,Tan J,Li X,Li H,Wu W,Wu Y,Zhang J,Gu L
Published figure using CD40 monoclonal antibody (Product # 16-0401-82) in Flow Cytometry
Mon Feb 01 00:00:00 EST 2021
Neuroimmune Consequences of eIF4E Phosphorylation on Chemotherapy-Induced Peripheral Neuropathy.
Frontiers in immunology
Agalave NM,Mody PH,Szabo-Pardi TA,Jeong HS,Burton MD
Published figure using CD40 monoclonal antibody (Product # 16-0401-82) in Flow Cytometry
Mon Sep 20 00:00:00 EDT 2021
Modulation of lactate-lysosome axis in dendritic cells by clotrimazole potentiates antitumor immunity.
Journal for immunotherapy of cancer
Wang Z,Xu F,Hu J,Zhang H,Cui L,Lu W,He W,Wang X,Li M,Zhang H,Xiong W,Xie C,Liu Y,Zhou P,Liu J,Huang P,Qin XF,Xia X
Published figure using CD40 monoclonal antibody (Product # 16-0401-82) in Flow Cytometry
Sat May 01 00:00:00 EDT 2021
A Genetic Map of the Response to DNA Damage in Human Cells.
Cell
Olivieri M,Cho T,Álvarez-Quilón A,Li K,Schellenberg MJ,Zimmermann M,Hustedt N,Rossi SE,Adam S,Melo H,Heijink AM,Sastre-Moreno G,Moatti N,Szilard RK,McEwan A,Ling AK,Serrano-Benitez A,Ubhi T,Feng S,Pawling J,Delgado-Sainz I,Ferguson MW,Dennis JW,Brown GW,Cortés-Ledesma F,Williams RS,Martin A,Xu D,Durocher D
16-0401-82 was used in Flow Cytometry to provide a rich resource to study this fundamental cellular system and has implications for the development and use of genotoxic agents in cancer therapy.
Thu Jul 23 00:00:00 EDT 2020
E6‑regulated overproduction of prostaglandin E2 may inhibit migration of dendritic cells in human papillomavirus 16‑positive cervical lesions.
International journal of oncology
Huang J,Diao G,Zhang Q,Chen Y,Han J,Guo J
Published figure using CD40 monoclonal antibody (Product # 16-0401-82) in Flow Cytometry
Wed Apr 01 00:00:00 EDT 2020
Senolytics prevent mt-DNA-induced inflammation and promote the survival of aged organs following transplantation.
Nature communications
Iske J,Seyda M,Heinbokel T,Maenosono R,Minami K,Nian Y,Quante M,Falk CS,Azuma H,Martin F,Passos JF,Niemann CU,Tchkonia T,Kirkland JL,Elkhal A,Tullius SG
Published figure using CD40 monoclonal antibody (Product # 16-0401-82) in Flow Cytometry
Thu Aug 27 00:00:00 EDT 2020
Vaccine elicitation of HIV broadly neutralizing antibodies from engineered B cells.
Nature communications
Huang D,Tran JT,Olson A,Vollbrecht T,Tenuta M,Guryleva MV,Fuller RP,Schiffner T,Abadejos JR,Couvrette L,Blane TR,Saye K,Li W,Landais E,Gonzalez-Martin A,Schief W,Murrell B,Burton DR,Nemazee D,Voss JE
16-0401 was used in Functional assays to show that HIV bnAb-engineered primary mouse B cells can be adoptively transferred and vaccinated in immunocompetent mice resulting in the expansion of durable bnAb memory and long-lived plasma cells.
Tue Nov 17 00:00:00 EST 2020
Tregitopes regulate the tolerogenic immune response and decrease the foetal death rate in abortion-prone mouse matings.
Scientific reports
Kedzierska AE,Lorek D,Slawek A,Chelmonska-Soyta A
Published figure using CD40 monoclonal antibody (Product # 16-0401-82) in Flow Cytometry
Mon Jun 29 00:00:00 EDT 2020
Polyanhydride Nanoparticles Induce Low Inflammatory Dendritic Cell Activation Resulting in CD8+ T Cell Memory and Delayed Tumor Progression.
International journal of nanomedicine
Darling R,Senapati S,Christiansen J,Liu L,Ramer-Tait AE,Narasimhan B,Wannemuehler M
Published figure using CD40 monoclonal antibody (Product # 16-0401-82) in Flow Cytometry
Mon Dec 07 00:00:00 EST 2020
cGAS/STING axis mediates a topoisomerase II inhibitor-induced tumor immunogenicity.
The Journal of clinical investigation
Wang Z,Chen J,Hu J,Zhang H,Xu F,He W,Wang X,Li M,Lu W,Zeng G,Zhou P,Huang P,Chen S,Li W,Xia LP,Xia X
Published figure using CD40 monoclonal antibody (Product # 16-0401-82) in Flow Cytometry
Tue Aug 13 00:00:00 EDT 2019
Polyamines Control eIF5A Hypusination, TFEB Translation, and Autophagy to Reverse B Cell Senescence.
Molecular cell
Zhang H,Alsaleh G,Feltham J,Sun Y,Napolitano G,Riffelmacher T,Charles P,Frau L,Hublitz P,Yu Z,Mohammed S,Ballabio A,Balabanov S,Mellor J,Simon AK
16-0401 was used in Flow cytometry/Cell sorting to reveal an unexpected autophagy regulatory mechanism mediated by eIF5A at the translational level, which can be harnessed to reverse immune senescence in humans.
Thu Oct 03 00:00:00 EDT 2019
Efficient oral vaccination by bioengineering virus-like particles with protozoan surface proteins.
Nature communications
Serradell MC,Rupil LL,Martino RA,Prucca CG,Carranza PG,Saura A,Fernández EA,Gargantini PR,Tenaglia AH,Petiti JP,Tonelli RR,Reinoso-Vizcaino N,Echenique J,Berod L,Piaggio E,Bellier B,Sparwasser T,Klatzmann D,Luján HD
Published figure using CD40 monoclonal antibody (Product # 16-0401-82) in Flow Cytometry
Mon Jan 21 00:00:00 EST 2019
Bryostatin-1 alleviates experimental multiple sclerosis.
Proceedings of the National Academy of Sciences of the United States of America
Kornberg MD,Smith MD,Shirazi HA,Calabresi PA,Snyder SH,Kim PM
Published figure using CD40 monoclonal antibody (Product # 16-0401-82) in Flow Cytometry
Tue Feb 27 00:00:00 EST 2018
FcεRI γ-Chain Negatively Modulates Dectin-1 Responses in Dendritic Cells.
Frontiers in immunology
Pan YG,Yu YL,Lin CC,Lanier LL,Chu CL
Published figure using CD40 monoclonal antibody (Product # 16-0401-82) in Flow Cytometry
Wed Nov 20 00:00:00 EST 2019
Discrimination of the heterogeneity of bone marrow‑derived dendritic cells.
Molecular medicine reports
Wang J,Dai X,Hsu C,Ming C,He Y,Zhang J,Wei L,Zhou P,Wang CY,Yang J,Gong N
Published figure using CD40 monoclonal antibody (Product # 16-0401-82) in Flow Cytometry
Wed Nov 01 00:00:00 EDT 2017
Batf3-dependent CD8α+ Dendritic Cells Aggravates Atherosclerosis via Th1 Cell Induction and Enhanced CCL5 Expression in Plaque Macrophages.
EBioMedicine
Li Y,Liu X,Duan W,Tian H,Zhu G,He H,Yao S,Yi S,Song W,Tang H
Published figure using CD40 monoclonal antibody (Product # 16-0401-82) in Flow Cytometry
Sat Apr 01 00:00:00 EDT 2017
Paeoniflorin Ameliorates Experimental Autoimmune Encephalomyelitis via Inhibition of Dendritic Cell Function and Th17 Cell Differentiation.
Scientific reports
Zhang H,Qi Y,Yuan Y,Cai L,Xu H,Zhang L,Su B,Nie H
Published figure using CD40 monoclonal antibody (Product # 16-0401-82) in Flow Cytometry
Mon Feb 06 00:00:00 EST 2017
Tumor-derived exosomes educate dendritic cells to promote tumor metastasis via HSP72/HSP105-TLR2/TLR4 pathway.
Oncoimmunology
Shen Y,Guo D,Weng L,Wang S,Ma Z,Yang Y,Wang P,Wang J,Cai Z
Published figure using CD40 monoclonal antibody (Product # 16-0401-82) in Flow Cytometry
Tue Jan 12 00:00:00 EST 2021
Combination immunotherapy with TLR agonists and checkpoint inhibitors suppresses head and neck cancer.
JCI insight
Sato-Kaneko F,Yao S,Ahmadi A,Zhang SS,Hosoya T,Kaneda MM,Varner JA,Pu M,Messer KS,Guiducci C,Coffman RL,Kitaura K,Matsutani T,Suzuki R,Carson DA,Hayashi T,Cohen EE
Published figure using CD40 monoclonal antibody (Product # 16-0401-82) in Flow Cytometry
Thu Sep 21 00:00:00 EDT 2017
N-glycosylation converts non-glycoproteins into mannose receptor ligands and reveals antigen-specific T cell responses in vivo.
Oncotarget
Kreer C,Kuepper JM,Zehner M,Quast T,Kolanus W,Schumak B,Burgdorf S
16-0401 was used in Flow cytometry/Cell sorting to analyse whether enforced N-glycosylation is a suited strategy to enhance the immunogenicity of non-glycosylated antigens for vaccination studies.
Tue Jan 24 00:00:00 EST 2017
Nuclear receptor expression atlas in BMDCs: Nr4a2 restricts immunogenicity of BMDCs and impedes EAE.
European journal of immunology
Saini A,Mahajan S,Gupta P
Published figure using CD40 monoclonal antibody (Product # 16-0401-82) in Flow Cytometry
Mon Aug 01 00:00:00 EDT 2016
Recruited monocytes modulate malaria-induced lung injury through CD36-mediated clearance of sequestered infected erythrocytes.
Journal of leukocyte biology
Lagassé HA,Anidi IU,Craig JM,Limjunyawong N,Poupore AK,Mitzner W,Scott AL
Published figure using CD40 monoclonal antibody (Product # 16-0401-82) in Flow Cytometry
Sun May 01 00:00:00 EDT 2016
Repulsive guidance molecule a blockade exerts the immunoregulatory function in DCs stimulated with ABP and LPS.
Human vaccines & immunotherapeutics
Xu X,Gao Y,Zhai Z,Zhang S,Shan F,Feng J
Published figure using CD40 monoclonal antibody (Product # 16-0401-82) in Flow Cytometry
Tue Aug 02 00:00:00 EDT 2016
MyD88/CD40 Genetic Adjuvant Function in Cutaneous Atypical Antigen-Presenting Cells Contributes to DNA Vaccine Immunogenicity.
PloS one
Collinson-Pautz MR,Slawin KM,Levitt JM,Spencer DM
Published figure using CD40 monoclonal antibody (Product # 16-0401-82) in Flow Cytometry
Wed May 31 00:00:00 EDT 2017
D-Alanylation of Teichoic Acids and Loss of Poly-N-Acetyl Glucosamine in Staphylococcus aureus during Exponential Growth Phase Enhance IL-12 Production in Murine Dendritic Cells.
PloS one
Lund LD,Ingmer H,Frøkiær H
Published figure using CD40 monoclonal antibody (Product # 16-0401-82) in Flow Cytometry
Thu Jul 14 00:00:00 EDT 2016
miR-150 regulates obesity-associated insulin resistance by controlling B cell functions.
Scientific reports
Ying W,Tseng A,Chang RC,Wang H,Lin YL,Kanameni S,Brehm T,Morin A,Jones B,Splawn T,Criscitiello M,Golding MC,Bazer FW,Safe S,Zhou B
16-0401 was used in Flow cytometry/Cell sorting to demonstrate a role for miR-150 in regulating B cell functions in adipose tissue.
Mon Feb 01 00:00:00 EST 2016
Clec4A4 is a regulatory receptor for dendritic cells that impairs inflammation and T-cell immunity.
Nature communications
Uto T,Fukaya T,Takagi H,Arimura K,Nakamura T,Kojima N,Malissen B,Sato K
16-0401 was used in Functional assays to investigate how Clec4A4 controls immune responses, showing that it is a regulatory receptor for dendritic cells that impairs inflammation and T-cell immunity.
Tue Apr 12 00:00:00 EDT 2016
CD19 and BAFF-R can signal to promote B-cell survival in the absence of Syk.
The EMBO journal
Hobeika E,Levit-Zerdoun E,Anastasopoulou V,Pohlmeyer R,Altmeier S,Alsadeq A,Dobenecker MW,Pelanda R,Reth M
16-0401 was used in Flow cytometry/Cell sorting to investigate pathways responsible for the maintenance and survival of mature Syk-deficient B cells.
Wed Apr 01 00:00:00 EDT 2015
The B-cell antigen receptor integrates adaptive and innate immune signals.
Proceedings of the National Academy of Sciences of the United States of America
Otipoby KL,Waisman A,Derudder E,Srinivasan L,Franklin A,Rajewsky K
16-0401 was used in Functional assays to suggest a model for integrating signals from the innate and the adaptive immune systems in control of B-cell immune response.
Tue Sep 29 00:00:00 EDT 2015
Adjuvants may reduce in vivo transfection levels for DNA vaccination in mice leading to reduced antigen-specific CD8+ T cell responses.
Human vaccines & immunotherapeutics
Rose AH,Hoffmann FW,Hara JH,Urschitz J,Moisyadi S,Hoffmann PR,Bertino P
Published figure using CD40 monoclonal antibody (Product # 16-0401-82) in Flow Cytometry
Mon May 16 00:00:00 EDT 2016
Critical role for syndecan-4 in dendritic cell migration during development of allergic airway inflammation.
Nature communications
Polte T,Petzold S,Bertrand J,Schütze N,Hinz D,Simon JC,Lehmann I,Echtermeyer F,Pap T,Averbeck M
16-0401 was used in Flow cytometry/Cell sorting to demonstrate that SDC4 plays an important role in asthma induction and indicate SDC4 as a possible target for therapeutic intervention in this disease.
Mon Jul 13 00:00:00 EDT 2015
Latent virus infection upregulates CD40 expression facilitating enhanced autoimmunity in a model of multiple sclerosis.
Scientific reports
Casiraghi C,Márquez AC,Shanina I,Horwitz MS
16-0401 was used in Flow cytometry/Cell sorting to investigate the cause of enhanced experimental autoimmune encephalomyelitis following infection with murine γ-herpesvirus 68.
Thu Sep 10 00:00:00 EDT 2015
The number of responding CD4 T cells and the dose of antigen conjointly determine the TH1/TH2 phenotype by modulating B7/CD28 interactions.
Journal of immunology (Baltimore, Md. : 1950)
Rudulier CD,McKinstry KK,Al-Yassin GA,Kroeger DR,Bretscher PA
16-0401 was used in Functional assays to show that a greater number of Ag-dependent CD4 T cell interactions are required to generate Th2 than Th1 cells.
Sun Jun 01 00:00:00 EDT 2014
Nizatidine, a small molecular compound, enhances killed H5N1 vaccine cell-mediated responses and protects mice from lethal viral challenge.
Human vaccines & immunotherapeutics
Wang S,Wu B,Xue J,Wang M,Chen R,Wang B
Published figure using CD40 monoclonal antibody (Product # 16-0401-82) in Flow Cytometry
Mon Jan 05 00:00:00 EST 2015
Deficiency of autophagy in dendritic cells protects against experimental autoimmune encephalomyelitis.
The Journal of biological chemistry
Bhattacharya A,Parillon X,Zeng S,Han S,Eissa NT
Published figure using CD40 monoclonal antibody (Product # 16-0401-82) in Flow Cytometry
Fri Sep 19 00:00:00 EDT 2014
Cancer immunotherapy employing an innovative strategy to enhance CD4+ T cell help in the tumor microenvironment.
PloS one
Song L,Yang MC,Knoff J,Wu TC,Hung CF
16-0401 was used in Flow cytometry/Cell sorting to investigate the effect of intratumoral injection of PADRE and the adjuvant CpG into HPV16 E7-expressing TC-1 tumours following cisplatin chemotherapy, showing potent antitumor effects and antigen-specific cell-mediated immune response.
Tue Dec 15 00:00:00 EST 2015
Agonistic anti-CD40 induces thyrocyte proliferation and promotes thyroid autoimmunity by increasing CD40 expression on thyroid epithelial cells.
Journal of immunology (Baltimore, Md. : 1950)
Kayes T,Fang Y,Yu S,Downey E,Wang S,Braley-Mullen H
16-0401 was used in Flow cytometry/Cell sorting to provide new information regarding the role of target tissue expression of CD40 in development of autoimmunity.
Mon Apr 15 00:00:00 EDT 2013
R-phycoerythrin-conjugated antibodies are inappropriate for intracellular staining of murine plasma cells.
Cytometry. Part A : the journal of the International Society for Analytical Cytology
Kim MS,Kim TS
16-0401-82 was used in Cell Culture to show that PE-conjugated antibodies are inappropriate for intracellular staining of murine plasma cells.
Wed May 01 00:00:00 EDT 2013
A new hypersensitive site, HS10, and the enhancers, E3' and Ed, differentially regulate Igκ gene expression.
Journal of immunology (Baltimore, Md. : 1950)
Zhou X,Xiang Y,Ding X,Garrard WT
16-0401 was used in Functional assays to conclude that the hypersensitive site, HS10, E3'', and Ed differentially regulate Igκ gene dynamics.
Thu Mar 15 00:00:00 EDT 2012
CD204 suppresses large heat shock protein-facilitated priming of tumor antigen gp100-specific T cells and chaperone vaccine activity against mouse melanoma.
Journal of immunology (Baltimore, Md. : 1950)
Qian J,Yi H,Guo C,Yu X,Zuo D,Chen X,Kane JM,Repasky EA,Subjeck JR,Wang XY
16-0401 was used in Western Blotting to propose that selective scavenger receptor interactions with heat shock proteinss may lead to highly distinct immunological consequences.
Thu Sep 15 00:00:00 EDT 2011
Involvement of calcitonin gene-related peptide and CCL2 production in CD40-mediated behavioral hypersensitivity in a model of neuropathic pain.
Neuron glia biology
Malon JT,Maddula S,Bell H,Cao L
16-0401 was used in Flow cytometry/Cell sorting to study the contribution of CGRP and CCL2 in CD40 mediated behavioral hypersensitivity in neuropathic pain.
Sun May 01 00:00:00 EDT 2011
Involvement of RhoH GTPase in the development of B-cell chronic lymphocytic leukemia.
Leukemia
Sanchez-Aguilera A,Rattmann I,Drew DZ,Müller LU,Summey V,Lucas DM,Byrd JC,Croce CM,Gu Y,Cancelas JA,Johnston P,Moritz T,Williams DA
16-0401 was used in Functional assays to investigate the function of RhoH in the B-cell lineage, showing that RhoH is involved in the development of B-cell chronic lymphocytic leukemia.
Fri Jan 01 00:00:00 EST 2010
Langerin+ CD8alpha+ dendritic cells are critical for cross-priming and IL-12 production in response to systemic antigens.
Journal of immunology (Baltimore, Md. : 1950)
Farrand KJ,Dickgreber N,Stoitzner P,Ronchese F,Petersen TR,Hermans IF
16-0401 was used in Flow cytometry/Cell sorting to investigate the role of langerin(+)CD8alpha(+) dendritic cells in priming T cells, showing that they are critical for cross-priming and IL-12 production in response to systemic antigens.
Tue Dec 15 00:00:00 EST 2009
The rap GTPases regulate B cell morphology, immune-synapse formation, and signaling by particulate B cell receptor ligands.
Immunity
Lin KB,Freeman SA,Zabetian S,Brugger H,Weber M,Lei V,Dang-Lawson M,Tse KW,Santamaria R,Batista FD,Gold MR
16-0401 was used in Binding experiments to show that Rap might play a key role in the activation of B cells by particulate and cell-associated antigens.
Tue Jan 01 00:00:00 EST 2008
Identification of regulatory functions for 4-1BB and 4-1BBL in myelopoiesis and the development of dendritic cells.
Nature immunology
Lee SW,Park Y,So T,Kwon BS,Cheroutre H,Mittler RS,Croft M
Published figure using CD40 monoclonal antibody (Product # 16-0401-82) in Flow Cytometry
Fri Aug 01 00:00:00 EDT 2008
Dynamics of lung macrophage activation in response to helminth infection.
Journal of leukocyte biology
Siracusa MC,Reece JJ,Urban JF,Scott AL
Published figure using CD40 monoclonal antibody (Product # 16-0401-82) in Flow Cytometry
Mon Dec 01 00:00:00 EST 2008
17beta-Estradiol's salutary effects on splenic dendritic cell functions following trauma-hemorrhage are mediated via estrogen receptor-alpha.
Molecular immunology
Kawasaki T,Choudhry MA,Suzuki T,Schwacha MG,Bland KI,Chaudry IH
16-0401 was used in Flow cytometry/Cell sorting to investigate the effect of 17beta-estradiol on splenic dendritic cell function, showing that beneficial effects occur via estrogen receptor-alpha.
Tue Jan 01 00:00:00 EST 2008
